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https://rtsf.natsci.msu.edu/genomics/gene-expression-analysis/index.aspx

RTSF Genomics Core offers services for investigators looking to utilize gene expression for their research. Our range of applications includes solutions for quantifying gene expression levels in nearly any species regardless of sample size. Services include Next Generation Sequencing using Illumina instruments, qPCR using the ABI QuantStudio 7 Flex Real-Time PCR System, and gene expression using NanoString nCounter system.

Proper citation: Michigan State University RTSF Genomics Core Facility (RRID:SCR_012406) Copy   

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http://www.scienceexchange.com/facilities/division-of-comparative-pathology-miami

The Division of Comparative Pathology is a full service veterinary pathology laboratory with both clinical pathology and histology services. Routine hematology and serum biochemistry testing is available for multiple species; we work well with low volume samples. Specialized testing is available or can be implemented as needed. Routine histology services including processing, embedding, and sectioning are available with many routine and special staining options.

Proper citation: UM Miller School of Medicine Division of Comparative Pathology (RRID:SCR_012492) Copy   

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http://www.scienceexchange.com/facilities/institute-for-behavioral-genetics

The Institute for Behavioral Genetics (IBG) is an organized research unit of the University of Colorado Graduate School dedicated to conducting and facilitating research on the genetic and environmental bases of individual differences in behavior. Founded in 1967, IBG is one of the top research facilities in the world for genetic research on behavior. Data collection and analysis is ongoing for several internationally renowned studies including the Colorado Adoption Project, the Colorado Twin Registry, the National Youth Survey Family Study, the Colorado Learning Disabilities Research Center, and the National Longitudinal Study of Adolescent Health. IBG is home to one of the nation''''s largest DNA repositories for research on human behavior, as well as housing a wide array of behaviorally and genetically defined lines of selected, recombinant inbred, transgenic, and knockout-gene mice. Current research includes studies of aging ( The Johnson Lab, The Link Lab), psychopathology, reading disability, cognition, substance abuse, behavioral development, and evolution. In addition to our research, we provide training opportunities for graduate students in affiliated programs at the University of Colorado campuses in Boulder and Denver. IBG receives funding from several federal agencies, principally through the National Institutes of Health, as well as a broad spectrum of Associations, Foundations and Programs. Welcome to our site, please feel free to contact us with any questions about our research or programs.

Proper citation: CU Boulder Institute for Behavioral Genetics (RRID:SCR_012495) Copy   

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http://www.scienceexchange.com/facilities/experimental-pathology-core-laboratory-uark

The Experimental Pathology Shared Resource Laboratory is a non-profit laboratory that provides investigators with centralized, comprehensive histological services. The laboratory currently works with over 70 investigators at the University of Arkansas, regionally, and nationally. By providing a centralized laboratory, we offer convenient access to all services within one facility, save costs for investigators and the institution, increase efficiency of sample processing, eliminate duplication of services and equipment, and maintain stringent quality control standards. The laboratory director, consultants, and technicians have extensive experience in routine histology and immunohistochemistry involving both human and animal tissues.

Proper citation: UAMS Experimental Pathology Core Laboratory (RRID:SCR_012373) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genoseq-core-facility-ucla

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 23, 2019. Core is involved in a broad range of scientific research. Medical research performed at the GenoSeq Core includes studies of human neurological disorders, such as: autism, bipolar disorder, and epilepsy; cancers of breast, colon, lung, and prostate; cardiac disease; and digestive disorders. Core also carries out studies of the genetics of non-human organisms. The GenoSeq Core is closely linked to the UCLA Bioinformatics Core in Gonda Center, which provides the computing power and sophisticated software needed to analyze and interpret the unprecedented volume of genetic data being generated with modern laboratory automation.

Proper citation: University of California Los Angeles GenoSeq Core Facility (RRID:SCR_012411) Copy   

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http://www.scienceexchange.com/facilities/genomics-and-epigenomics-shared-resource-gesr-georgetown

The Genomics & Epigenomics Shared Resource (GESR) provides services for various high throughput experiments including gene expression profiling, SNP genotyping, CNV analysis, DNA methylation, microRNA expression profiling, siRNA screening, DNA/RNA isolation, RNA quality assessment, DNA plating and assay preparation, DNA sequencing, and fragment analysis. GESR uses state-of-the-art instruments and assays to provide these services. These include Affymetrix Microarray System, Agilent Microarray System, Applied Biosystems TaqMan assays, Illumina BeadXpress, Qiagen PyromarkMD, Qiagen Qiacube, Agilent Bioanalyzer, Beckman Multimek NXP Robotic Liquid Handling System, and Applied Biosystems Sequence Analyzer. In addition, GESR houses several user-operated specialized instruments for which the shared resource personnel provide technical support and training.

Proper citation: Georgetown Genomics and Epigenomics Shared Resource (RRID:SCR_012498) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/microarray-resource-core-bu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Microarray Resource Core offers the full line of microarray products available from Affymetrix. This includes expression profiling, miRNA, exon, genotyping, resequencing, and tiling arrays. As part of our standard service, the resource provides assistance with experimental design and data analysis. Arrays for other organisms are available; please contact us for with specific requests.

Proper citation: Boston University Microarray Resource Core (RRID:SCR_012491) Copy   

•   Source: SciCrunch Registry

https://genomics.umn.edu/

Provides genomic technologies and services to researchers and clinicians. Services include Next Generation Sequencing, Epigenomics, SARS-CoV-2 services, GBS, Third Generation Sequencing, NGS Library Creation, Sanger Sequencing, DNA and RNA Extraction, Gene Expression.

Proper citation: University of Minnesota Genomics Center Core Facility (RRID:SCR_012413) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/animal-and-food-sciences-department-udel

We offer a wide range of disciplines including virology, physiology, nutrition, microbiology, immunology, molecular biology, engineering, and genomics. Our research addresses contemporary and future scientific challenges by using cutting edge technologies with the goal of assisting stakeholders in the poultry, livestock, and food industries.

Proper citation: UD Animal and Food Sciences Department (RRID:SCR_012415) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-of-biomedical-analysis-tsinghua-university

The center of biomedical analysis (CBA) is a multiple discipline platform. CBA is bound to provide the best services and support to our investigators in all research fields. We welcome any suggestions and recommendations. In consultation with the Advisory Committee for each facility, the facility manager sets up the fee structures and makes decision on equipment purchase and upgrade.

Proper citation: Tsinghua University Center of Biomedical Analysis (RRID:SCR_012382) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-biophysical-sciences-and-engineering-cbse

Since 1986, The Center for Biophysical Sciences and Engineering (CBSE) has integrated our strengths to become a leading structural biology center capable of embracing the _������������_genes to drug_���� paradigm. We are one of the world''''s largest Structure Based Drug Discovery facilities with over 110 employees, including 15 Ph.D. level crystallographers. The CBSE is centered on a suite of integrated high throughput laboratories allowing us to offer a cost-effective platform of discovery services designed to increase the efficiency and success for drug discovery projects with industry, academic and government partners.

Proper citation: UAB Center for Biophysical Sciences and Engineering (RRID:SCR_012509) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-core-facility-uchicago

Flow Cytometry Facility at the University of Chicago is committed to providing the highest quality services to all its investigators.

Proper citation: UChicago Flow Cytometry Core Facility (RRID:SCR_012508) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-microarray-core-facility-duke

The Duke Microarray Facility provides services for the analysis of gene expression. The facility is operated jointly with the Duke Cancer Institute and provides: Affymetrix Microarrays Agilent Microarrays Real-Time PCR RNA Quality Check with Agilent Bioanalyzer The Microarray Facility also maintains a comprehensive database server to manage the massive amounts of data generated by microarray analysis. The facility provides data analysis support through various software packages as well as gene annotation support.

Proper citation: Duke DNA Microarray Core Facility (RRID:SCR_012629) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/w-m-keck-biomedical-mass-spectrometry-laboratory-virginia

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. W.M. Keck Biomedical Mass Spectrometry Laboratory within the Biomolecular Research Facility identifies and analyzes proteins from gels and solution using current mass spectrometry techniques. There are techniques to compare samples which have different amounts of the same proteins. Analyses available: - Protein identification and sequencing from gel or solution by either peptide mass fingerprinting or ESI-LC/MS/MS at the low femtomole level. - Analysis of protein mixtures such as tissue and media analysis of tissue samples prepared by Laser Capture Microdissection - Proteomics, comparison of proteins in tissue samples using chemical/isotopic labels or label free analysis - Absolute quantitation of proteins using labeled peptides and selective reaction monitoring - Identification of phosphorylation sites using titanium dioxide enrichment - Identification of post-translational modifications (deamination, ubiquitination, etc) - De Novo (manual) sequence analysis of novel proteins to obtain sufficient sequence data for cloning - High resolution, high mass accuracy measurements of peptides and small proteins - Confirmation of peptide identity by MALDI mass measurements - Identification of binding partners Equipment Our current mass spectrometers: - Thermo Scientific LTQ Orbitrap Velos for high accuracy, high sensitivity analysis - Bruker Microflex for mass analysis by MALDI - Thermo Scientific TSQ Quantum Access MAX triple quadrupole instrument Sample types analyzed: - gel bands, stained with Coomassie, silver, fluorescent stains - proteins in solution - tissue samples - media - Laser Capture Microdissection tissue samples.

Proper citation: UVa W.M. Keck Biomedical Mass Spectrometry Laboratory (RRID:SCR_012589) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/advanced-optical-microscopy-facility

The Advanced Optical Microscopy Facility (AOMF) is centrally located in the Discovery District in Toronto, Ontario, serving University Health Network as well as external academic and industrial users. It is the largest microscopy facility in Canada with instruments at Princess Margaret Hospital and Toronto General Hospital. With over 30 instruments and 4 staff members, the AOMF is equipped to help you with nearly any optical microscopy application including: confocal, multiphoton, FRAP, FRET, live-cell, timelapse, spectral unmixing, in-vivo bioluminescence and fluorescence, whole-slide scanning, 3D rendering, colocalization and more. We offer: Free consultations to determine which microscopes would best suit your application Comprehensive training and support on our various instruments Full-service image capture and analysis (a great way to get started quickly) High-resolution whole slide scanning service for histology slides Practical courses on microscopy, including one-on-one hands-on sessions (eg: Fundamentals of Microscopy) and larger workshops tailored to your group''''s applications Software and training for image processing and quantification

Proper citation: UHN Advanced Optical Microscopy Facility (RRID:SCR_012622) Copy   

•   Source: SciCrunch Registry

https://www.umassmed.edu/MSF/Proteomics/

The University of Massachusetts Medical School Proteomics and Mass Spectrometry Facility is an analytical laboratory resource offering state-of-the-art proteomic, lipid, and small molecule mass spectrometric analyses to both the academic and external scientific community. This includes resources for study design, sample preparation and cleanup, sample fractionation, instrumentation, informatics, data interpretation, and publication assistance.

Proper citation: UMMS Proteomics and Mass Spectrometry Facility (RRID:SCR_012500) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-microarray-core-facility-ualbany

Core provides microarray services for Affymetrix GeneChip arrays, Agilent microarrays, NimbleGen microarrays and custom-produced spotted cDNA microarrays. Projects developed through DNA Microarray Center have made use of arrays from variety of genomes, eukaryotic, prokaryotic, and plant. Core services includes RNA/DNA isolation, gene expression, miRNA, Chip-chip, Rip-chip and DNA methylation services. Provides bioinformatics tools for further analysis of results of expression experiments.

Proper citation: University at Albany Center for Functional Genomics DNA Microarray Core Facility (RRID:SCR_012502) Copy   

•   Source: SciCrunch Registry

https://www.mcgill.ca/cian/

Core facility at Biology Department in McGill Faculty of Science. Expertise in Light Microscopy and Image Analysis. Provides light microscopes, ranging from Point Scanning and Spinning Disc Confocals to Multi-Photon, TIRF, Light Sheet and Super-Resolution microscopes. Provides services in Automation/High throughput screening (liquid handler, pinning robot), Protein expression and antibody production. Users get training.

Proper citation: McGill Cell Imaging and Analysis Network Core Facility (RRID:SCR_012623) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cellular-and-molecular-biology-core-uvm

This is a free facility for everyone at the University of Vermont; however, preference will be given to the principle investigators listed on the COBRE grant, followed by members of the neuroscience community and finally, the university as a whole. Check in advance when planning experiments to determine space and equipment availability.

Proper citation: UVM Cellular and Molecular Biology Core (RRID:SCR_012505) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/stem-cell-core-facility-usc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2024. USC Stem Cell Core facility is a CIRM funded comprehensive support center and central hub for the provision of knowledge, resources and state of the art technology to researchers working with stem cells. Our primary aims are to facilitate stem cell and biomedical research at USC and the LA area and to develop new technologies for working with pluripotent stem cells. We offer a wide range of services in the following areas: Cells and Reagents Reproducibility in experimental science is dependent on homogeneity and consistency. One of the primary aims of the USC Stem Cell Core is to standardize stem cell research by providing quality controlled cells and reagents. Equipment The USC Stem Cell Core is a shared laboratory space housing communal cell culture workstations, a state of the art imaging core, spectral karyotyping facilities, a Q-PCR machine, fully equipped molecular biology work stations and a variety of equipment for performing histological analysis. Flow cytometry and high content screening equipment are made available through the FACS core. Laboratory Space As a shared research facility we offer communal laboratory space for investigators to conduct collaborative or start up research involving stem cells. Our goal is to expand stem cell research in the LA area and to encourage collaboration between novice and seasoned researchers. Technical Assistance The USC Stem Cell Core is staffed with a team of highly experienced technicians, boasting a combined technical expertise of over 60 years. We provide comprehensive assistance, which includes a biobanking and histology service. Training and Education Training and education are pivotal to the advancement of Stem Cell Research. The USC Stem Cell Core offers a broad range of educational services including technical protocols, one on one customized training and a week long course covering human pluripotent stem cell culture techniques. Research and Development The USC Stem Cell Core Research and Development program was established with two main aims: 1) to develop and centralize new technologies for working with human pluripotent stem cells, 2) to support researchers embarking on collaborative and pilot projects.

Proper citation: USC Stem Cell Core Facility (RRID:SCR_012628) Copy   

•   Source: SciCrunch Registry