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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PLEXdb - Plant Expression Database
 
Resource Report
Resource Website
10+ mentions
PLEXdb - Plant Expression Database (RRID:SCR_006963) PLEXdb analysis service resource, data analysis service, data or information resource, data repository, database, portal, production service resource, service resource, storage service resource, topical portal PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets. gene expression, plant, plant pathogen, genotype, phenotype, genetic, physical, pathway, plant biology, compare, functional genomics, expression profiling, expression atlas, pathogen, genome, anova, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: FuncExpression
has parent organization: Iowa State University; Iowa; USA
UniNSF DBI-0543441;
NSF IOS-0922746;
USDA 3625-21000-049-00D
PMID:22084198 biotools:plexdb, r3d100011516, nlx_149236 https://bio.tools/plexdb, https://doi.org/10.17616/R39D13 SCR_006963 PLEXdb - Gene expression resources for plants and plant pathogens, Plant Expression Database 2026-09-12 01:00:12 21
PASA
 
Resource Report
Resource Website
1000+ mentions
PASA (RRID:SCR_014656) data analysis software, data processing software, sequence analysis software, software application, software resource Gene structure annotation and analysis tool that uses spliced alignments of expressed transcript sequences to automatically model gene structures. It also incorporates gene structures based on transcript alignments into existing gene structure annotations. It is one component of a larger eukayotic annotation pipeline implemented at the Broad Institute. gene structure, annotation, gene structure analysis tool, spliced alignment, transcript sequence, bio.tools is used by: BRO_annotation
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/nar/gkg770 Available for download biotools:PASA https://bio.tools/PASA SCR_014656 Program to Assemble Spliced Alignments (PASA), Program to Assemble Spliced Alignments 2026-09-12 01:00:17 1123
Molecular Dynamics Workflow (BioKepler)
 
Resource Report
Resource Website
1+ mentions
Molecular Dynamics Workflow (BioKepler) (RRID:SCR_014389) data processing software, software application, software resource, workflow software A workflow for running molecular dynamics simulations. It can be used for all-atom molecular dynamic simulations, which involve five steps of minimization, one step of heating, three steps of equilibration, and one or more instances of production. The input is a set of directories that include the MD simulation input scripts, system topology and coordinate files. Output files are list of plots, simulation trajectories, intermediate files, restart files, and the like. workflow, MD, molecular dynamics, simulation, software, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: bioKepler
has parent organization: University of California at San Diego; California; USA
NIGMS P41GM103426 Requires Linux biotools:ambergpumdsimulation http://nbcr.ucsd.edu/data/downloads/workflows/, https://bio.tools/ambergpumdsimulation SCR_014389 Molecular Dynamics Workflow, AmberGPUMDSimulation, Molecular Dynamics Workflow Software, Amber GPUMD Simulation 2026-09-12 01:00:17 1
PLINK/SEQ
 
Resource Report
Resource Website
50+ mentions
PLINK/SEQ (RRID:SCR_013193) software application, software library, software resource, software toolkit An open-source C/C++ library for working with human genetic variation data. The specific focus is to provide a platform for analytic tool development for variation data from large-scale resequencing projects, particularly whole-exome and whole-genome studies. However, the library could in principle be applied to other types of genetic studies, including whole-genome association studies of common SNPs. (entry from Genetic Analysis Software) gene, genetic, genomic, c/c++, r, macos, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: PLINK
has parent organization: Harvard University; Cambridge; United States
Open unspecified license nlx_154213, biotools:plink-seq https://bio.tools/plink-seq SCR_013193 2026-09-12 01:00:16 77
HiC-Pro
 
Resource Report
Resource Website
100+ mentions
HiC-Pro (RRID:SCR_017643) data processing software, software application, software resource, workflow software Software tool as optimized and flexible pipeline for Hi-C data processing. Used to process Hi-C data, from raw fastq files, paired end Illumina data, to normalized contact maps. Hi-C, data, raw, fastq, file, paired, Illumina, normalized, contact, map, bio.tools is listed by: Debian
is listed by: bio.tools
ABS4NGS project ;
ERC Advanced Investigator award ;
European Commission ;
European Research Coucil ;
France Genomique National infrastructure ;
Howard Hughes Medical Institute ;
Labex Deep ;
National Human Genome Research Institute ;
Paris Alliance of Cancer Research Institutes
PMID:26619908 Free, Available for download, Freely available biotools:hic-pro https://bio.tools/hic-pro SCR_017643 2026-09-12 01:00:20 238
OrthoFinder
 
Resource Report
Resource Website
1000+ mentions
OrthoFinder (RRID:SCR_017118) data analysis software, data processing software, software application, software resource Software Python application for comparative genomics analysis. Finds orthogroups and orthologs, infers rooted gene trees for all orthogroups and identifies all of gene duplcation events in those gene trees, infers rooted species tree for species being analysed and maps gene duplication events from gene trees to branches in species tree, improves orthogroup inference accuracy. Runs set of protein sequence files, one per species, in FASTA format. comparative, genomic, analysis, find, orthogroup, ortholog, infer, gene, tree, duplicate, accuracy, protein, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Bill and Melinda Gates Foundation ;
UKAID
PMID:26243257
DOI:10.1101/466201
Free, Available for download, Freely available biotools:OrthoFinder, OMICS_09733, BioTools:OrthoFinder https://bio.tools/OrthoFinder, https://bio.tools/OrthoFinder, https://bio.tools/OrthoFinder SCR_017118 OrthoFinder2, OrthoFinder 2026-09-12 01:00:20 3413
tximport
 
Resource Report
Resource Website
100+ mentions
tximport (RRID:SCR_016752) data analysis software, data processing software, software application, software resource Software R package for importing pseudoaligned reads into R for use with downstream differential expression analysis. Used for import and summarize transcript level estimates for transcript and gene level analysis. pseudoaligned, reads, R, differential, expression, analysis, gene, transcript, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
works with: edgeR
works with: DESeq2
European Commission ;
NCI T32 CA009337;
SNSF 143883
DOI:10.12688/f1000research.7563.1 Free, Available for download, Freely available biotools:tximport https://bioconductor.org/packages/tximport/, https://bioconductor.org/packages/devel/bioc/vignettes/tximport/inst/doc/tximport.html, https://github.com/F1000Research/tximport, https://bio.tools/tximport https://zenodo.org/record/35123#.W_w3behKiM8 SCR_016752 tximport v1.4.0 2026-09-12 01:00:19 100
Nephele
 
Resource Report
Resource Website
10+ mentions
Nephele (RRID:SCR_016595) analysis service resource, data analysis service, production service resource, service resource, software resource, web application Cloud based platform for simplified, standardized and reproducible microbiome data analysis. Allows users to process microbiome datasets through pipelines of existing software tools. microbiome, datasets, process, analyze, metagenome, sequencing, data, bio.tools uses: mothur
uses: QIIME
uses: biobakery
uses: A5-miseq
is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
has parent organization: OCICB
NIH Department of Health and Human Services GS35F0373X PMID:29028892 Free, Available for download, Freely available biotools:nephele https://github.com/niaid/Nephele, https://bio.tools/nephele SCR_016595 2026-09-12 01:00:19 36
scanpy
 
Resource Report
Resource Website
100+ mentions
scanpy (RRID:SCR_018139) data analysis software, data processing software, software application, software resource Software Python tool for large scale single cell gene expression data analysis. Integrates analysis possibilities of established R-based frameworks, provides pre processing, visualization, graph-drawing and diffusion maps, clustering, identification of marker genes for clusters via differential expression tests and pseudo temporal ordering via diffusion pseudo time. Large scale, single cell, gene expression, data analysis, R, pre processing, visualization, graph drawing, diffusion map, clustering, marker gene, differential expression test, bio.tools uses: BBKNN
is used by: triku
is used by: MUON
is listed by: Debian
is listed by: bio.tools
is related to: Anndata
has plug in: infercnvpy
German Research Foundation ;
Helmholtz Postdoc Programme
PMID:29409532 Free, Available for download, Freely available biotools:scanpy, BioTools:scanpy https://icb-scanpy.readthedocs-hosted.com/en/stable/, https://bio.tools/scanpy, https://bio.tools/scanpy, https://bio.tools/scanpy SCR_018139 Single Cell Analysis in Python 2026-09-12 01:00:20 256
Epigenomics Workflow on Galaxy and Jupyter
 
Resource Report
Resource Website
1+ mentions
Epigenomics Workflow on Galaxy and Jupyter (RRID:SCR_017544) data analysis software, data or information resource, data processing software, narrative resource, software application, software resource, training material, workflow Software tool as epigenomics analysis pipeline for analysis of ChIP-Seq and RNA-Seq data using Docker images containing Galaxy and Jupyter. Epigenomic, analysis, pipeline, ChIP-Seq, RNA-Seq, data, Galaxy, Jupyter, bio.tools is listed by: bio.tools
is listed by: Debian
Agencia Estatal de Investigación of Spain SEV-2016-0672 (2017-2021) Free, Available for download, Freely available biotools:Epigenomics_Workflow_on_Galaxy_and_Jupyter https://zenodo.org/record/3298029, https://bio.tools/Epigenomics_Workflow_on_Galaxy_and_Jupyter SCR_017544 REA pipeline 2026-09-12 01:00:20 2
ngsRelate
 
Resource Report
Resource Website
1+ mentions
ngsRelate (RRID:SCR_016588) data analysis software, data processing software, software application, software resource Software tool for estimating pairwise relatedness from next-generation sequencing data. estimating, pairwise, relatedness, next, generation, sequencing, data, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
Danish Council for Independent Research ;
Danish National Research Foundation
PMID:26323718 Free, Available for download, Freely available biotools:ngsRelateV2, biotools:ngsrelate https://bio.tools/ngsRelateV2, https://bio.tools/ngsrelate http://www.popgen.dk/software/index.php?title=NgsRelate&oldid=694 SCR_016588 ngsRelateV2 2026-09-12 01:00:19 6
ComplexHeatmap
 
Resource Report
Resource Website
1000+ mentions
ComplexHeatmap (RRID:SCR_017270) data analysis software, data processing software, data visualization software, software application, software resource Software package to arrange multiple heatmaps and support various annotation graphics. Used to visualize associations between different sources of data sets and to reveal potential patterns. arrange, multiple, heatmap, visualize, data, pattern, genomic, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
BMBF ;
German Cancer Research Center-Heidelberg Center for Personalized Oncology
PMID:27207943 Free, Available for download, Freely available biotools:complexheatmap https://github.com/jokergoo/ComplexHeatmap, https://bio.tools/complexheatmap SCR_017270 2026-09-12 01:00:20 3949
SWISS-MODEL
 
Resource Report
Resource Website
1000+ mentions
SWISS-MODEL (RRID:SCR_018123) data access protocol, data or information resource, service resource, software resource, web service Software tool as fully automated protein structure homology modeling server, accessible via ExPASy web server, or from program DeepView Swiss Pdb-Viewer. Structural bioinformatics web-server dedicated to homology modeling of 3D protein structures. Used to make protein modelling accessible to all biochemists and molecular biologists. 3D protein structure, homology modeling server, protein modeling, structural bioinformatics, automated comparative modeling, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
is related to: Swiss-PdbViewerDeepViewv4.0
has parent organization: University of Basel; Basel; Switzerland
provides: SWISS-MODEL Repository
PMID:12824332 Free, Freely available biotools:swiss-model_workspace, biotools:swiss_model https://bio.tools/swiss_model, https://bio.tools/swiss-model_workspace SCR_018123 2026-09-12 01:00:20 4218
DrivAER
 
Resource Report
Resource Website
1+ mentions
DrivAER (RRID:SCR_019076) data analysis software, data processing software, software application, software resource Software tool as method for identification of driving transcriptional programs based on AutoEncoder derived Relevance scores. Infers relevance scores for transcriptional programs with respect to specified outcomes of interest in single-cell RNA sequencing data, such as psuedotemporal ordering or disease status.Used for manifold interpretation in scRNA-seq data. Manifold interpretation, scRNAseq data, relevance scores infering, transcriptional program, psuedotemporal ordering, disease status, data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:drivaer https://bio.tools/drivaer SCR_019076 Driving transcriptional programs using AutoEncoder based Relevance scores 2026-09-12 01:00:21 1
IMGT HighV-QUEST
 
Resource Report
Resource Website
10+ mentions
IMGT HighV-QUEST (RRID:SCR_018196) alignment software, analysis service resource, data or information resource, data processing software, image analysis software, portal, production service resource, service resource, software application, software resource Next generation B and T cell sequence alignment and characterization online surface by IMGT. Web portal for immunoglobulin (IG) or antibody and T cell receptor (TR) analysis from NGS high throughput and deep sequencing. Next generation sequencing, B cell, T cell, sequence alignment, immunoglobulin, antibody, T cell receptor, analysis, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
CNRS ;
GENCI ;
MESR ;
NHMRC ;
Université Montpellier 2 ;
France
PMID:22647994
PMID:23995877
PMID:22665256
Restricted biotools:IMGt_HighV-QUESt https://bio.tools/IMGT_HighV-QUEST SCR_018196 IMGT/HighV QUEST, IMGT/HighV-QUEST, IMGT web portal 2026-09-12 01:00:21 15
PM4NGS
 
Resource Report
Resource Website
1+ mentions
PM4NGS (RRID:SCR_019164) data analysis software, data management software, data processing software, software application, software resource, software toolkit, workflow software Software tool to generate standard organizational structure for Next Generation Sequencing data analysis. Includes directory structure for project, several Jupyter notebooks for data management and CWL workflows for pipeline execution. NGS workflow, standard organizational structure generation, Next Generation Sequencing data, NGS data analysis, NGS data analysis workflow, data integration, Jupyter notebook, CWL format, bio.tools is listed by: bio.tools
is listed by: Debian
Intramural Research Program of the National Library of Medicine NIH DOI:10.7490/f1000research.1117155.1 Free, Freely available biotools:pm4ngs https://bio.tools/pm4ngs SCR_019164 Project Manager for Next Generation Sequencing 2026-09-12 01:00:21 1
SIGNOR
 
Resource Report
Resource Website
50+ mentions
SIGNOR (RRID:SCR_018485) data or information resource, data repository, database, service resource, storage service resource Software application to organize and store in structured format signaling information published in scientific literature. Information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. Each relationship is linked to literature reporting experimental evidence. Each node is annotated with chemical inhibitors that modulate its activity. Signaling information is mapped to human proteome. SIGNOR 2.0 stores manually annotated causal relationships between proteins and other biologically relevant entities including chemicals, phenotypes, complexes, etc with compliance to FAIR data principles. Signal transduction data, signaling information, published data collection, activity flow, chemical inhibitor, human proteome, manually annotated data, protein, protein relationship, FAIR data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: REDIportal
ELIXIR-IIB ;
EMBL-EBI ;
Italian Association for Cancer Research ;
Italian Node of the European ELIXIR infrastructure
PMID:31665520 Free, Available for download, Freely available biotools:signor https://bio.tools/signor SCR_018485 SIGnaling Network Open Resource, SIGNOR 2.0 2026-09-12 01:00:21 61
EvidenceFinder
 
Resource Report
Resource Website
1+ mentions
EvidenceFinder (RRID:SCR_013764) software resource, web application A web application to assist in the identification of articles and research related to literature search terms. The search covers full text articles in the Europe PMC repository. Relevant papers are suggested to users based on the scientific term searched and the selection of questions, generated by the application, relevant to term searched. web application, software resource, literature search, bio.tools is used by: Europe PubMed Central
is listed by: Connected Researchers
is listed by: Debian
is listed by: bio.tools
is related to: Connected Researchers
is related to: Europe PubMed Central
has parent organization: Europe PubMed Central
Wellcome Trust 098231 DOI:10.1093/nar/gku1061 Free, Public biotools:evidence_finder https://bio.tools/evidence_finder SCR_013764 2026-09-12 01:00:32 3
MRIcron
 
Resource Report
Resource Website
1000+ mentions
MRIcron (RRID:SCR_002403) MRIcron data processing software, data visualization software, software application, software resource Software tool as a cross-platform NIfTI format image viewer. Used for viewing and exporting of brain images. MRIcroGL is a variant of MRIcron. NIfTI, format, image, viewer, exporting, brain, image, processing, data, bio.tools is used by: XFSL: An FSL toolbox
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is listed by: neurodebian
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Colour maps for brain imaging
has parent organization: University of South Carolina; South Carolina; USA
PMID:17583985
PMID:11568431
BSD License biotools:MRIcron, nif-0000-00122 https://sources.debian.org/src/mricron/, http://www.mccauslandcenter.sc.edu/mricro/, http://www.nitrc.org/projects/mricron, http://neuro.debian.net/pkgs/mricron.html, https://bio.tools/MRIcron SCR_002403 mricron - magnetic resonance image conversion viewing and analysis 2026-09-12 01:00:35 2312
fgsea
 
Resource Report
Resource Website
100+ mentions
fgsea (RRID:SCR_020938) data analysis software, data processing software, software application, software resource Software R package for fast preranked gene set enrichment analysis. Allows to make more permutations and get more fine grained p-values, which allows to use accurate stantard approaches to multiple hypothesis correction. Gene set enrichment analysis, preranked gene set, multiple hypothesis correction, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
DOI:10.1101/060012 Free, Available for download, Freely available biotools:fgsea https://github.com/ctlab/fgsea/, https://bio.tools/fgsea SCR_020938 fast gene set enrichment analysis, Fast Gene Set Enrichment Analysis, FGSEA 2026-09-12 12:59:48 237

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