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https://www.lerner.ccf.org/cores/engineering/

Core provides mechanical and biomedical engineering expertise and services. Specializes in early-stage development and proof-of-concept prototypes. Utilizes 3D modeling, 3D printing, nitinol shape setting, and laser cutting to design and fabricate custom medical devices, test fixtures, and CT/MRI-based anatomy models.

Proper citation: Cleveland Clinic Lerner Research Institute Engineering Core Facility (RRID:SCR_026816) Copy   

•   Source: SciCrunch Registry

https://markerdb.ca/

Database that attempts to consolidate information on known clinical and selected set of pre-clinical biomarkers into single resource. Database includes five major types of biomarkers (condition specific, protein, chemical, karyotypic and genetic) and six biomarker categories (diagnostic, risk, prognostic, safety, monitoring, and response). Provides information such as: biomarker names and synonyms, associated conditions or pathologies, detailed disease descriptions, detailed biomarker descriptions, biomarker specificity, sensitivity and ROC curves, standard reference values (for protein and chemical markers), variants (for SNP or genetic markers), sequence information (for genetic and protein markers), molecular 2D and 3D structures (for protein and chemical markers), tissue or biofluid sources (for protein and chemical markers), chromosomal location and structure (for genetic and karyotype markers), clinical approval status and relevant literature references. Users can browse the data by conditions, condition categories, biomarker types, biomarker categories or search by sequence similarity through the advanced search function.

Proper citation: MarkerDB (RRID:SCR_026817) Copy   

•   Source: SciCrunch Registry

http://pl64.com

Software versatile all-purpose image and graphics editor for Windows, macOS, and Linux (via Wine) that combines raster (bitmap) and vector editing, making it a strong, affordable alternative to Adobe Photoshop, with features like layers, masks, color management (CMYK, Lab, 16-bit), batch processing, and web tools, presented in a comprehensive yet sometimes retro-looking interface . You can edit images or optimize them for the web, but you can also prepare print-ready PDF data.

Proper citation: Photoline (RRID:SCR_027878) Copy   

•   Source: SciCrunch Registry

https://camera.niehs.nih.gov/

Interactive database and user interface providing online access to validated alternative methods for U.S. regulatory and other contexts of use. Central hub and unified resource of validated alternative methods that enhances accessibility to validation study reports, data, protocols / SOPs, and information on regulatory guidance.Users can filter searches by alternative method types, defined approaches, Test Method Endpoint, and regulatory guidance.

Proper citation: Collection of Alternative Methods for Regulatory Application (CAMERA) (RRID:SCR_027893) Copy   

•   Source: SciCrunch Registry

https://icv.institutducerveau.org/service/overview-celis-ips/

As part of the cellular engineering and vectorology core facility (ICV), the iPSC core facility (ICV-iPS) proposes the generation and the genetic engineering of human induced pluripotent stem cells to internal research teams, external academic teams, and industrial partners. Services include generation of human iPSc with Sendai virus, full molecular and functional characterization of iPSc clones, genetic engineering of human iPSc with CRISPR/Cas9 system and theoretical and practical learning sessions on human iPSc culture. The core facility provides also access to L2 cell culture box dedicated to human iPSc culture.

Proper citation: Paris Brain Institute iPSC Core Facility (RRID:SCR_027891) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/integrated-genomics-operation-igo

Core provides services and expertise to Center investigators interested in evaluating gene expression, chromosome structure, and nucleotide sequence on a broad scale. Enables basic, clinical, and translational research projects across the Center. Through its production group, the Core enables genomic and transcriptomic analyses and has the expertise to process challenging samples from all origins (tissue, dissociated single cells and cell pellets, paraffin curls, blood, serum, etc.). Bulk DNA/RNA assays operate in highly automated environment, from sample reception to sequencing library preparation.

Proper citation: Memorial Sloan Kettering Cancer Center Integrated Genomics Operation Core Facility (RRID:SCR_027801) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/nuclear-magnetic-resonance-analytical

Core provides analytical services, access and education for analytical instrumentation and related shared scientific resources. Instrumentation includes high field nuclear magnetic resonance, mass spectrometry and optical spectroscopic instruments. Facility offers investigators the ability to monitor chemical reactions, analysis for determination of molecular structure, chemical mechanisms, purity, stability, biological uptake and other properties of chemical compounds.

Proper citation: Memorial Sloan Kettering Cancer Center Nuclear Magnetic Resonance (Analytical) Core Facility (RRID:SCR_027804) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/mouse-genetics

Core facilitates the use of mouse molecular genetics at MSK for in vivo studies of gene functions germane to cancer. Provides expertise in generation and effective use of genetically engineered mouse (GEM) models—namely, molecular and cell biology, embryo micromanipulation, and reproductive biology. Molecular and cellular biology services cover design and assembly of genome engineering reagents, such as donor transgenes and CRISPR/Cas9; performing all aspects of gene targeting in mouse embryonic stem (ES) cells; identification and verification of alleles carried by a generated GEM model; and establishment of new ES cells from a variety of GEM lines. Provides consultation and training for the design and production of GEM models, ES cell culture and manipulation, and mouse reproduction and genetic crosses.

Proper citation: Memorial Sloan Kettering Cancer Center Mouse Genetics Core Facility (RRID:SCR_027803) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/pro-cel

Core supports MSK investigators who wish to capture self-reported information from culturally diverse patients, caregivers, clinical staff, and community members. The faculty of the PRO-CEL Core are nationally recognized social and behavioral scientists and community engagement experts who provide technical assistance to all users throughout multiple stages of research, including grant and protocol development, research study assistant and support staff training, and result dissemination. Provides methodological support for clinical trial, behavioral, and population-based research that seeks to engage community or minority populations.

Proper citation: Memorial Sloan Kettering Cancer Center Patient- Reported Outcomes, Community Engagement, and Language Core Core Facility (RRID:SCR_027805) Copy   

•   Source: SciCrunch Registry

https://github.com/janclemenslab/glm_utils

Software tools for fitting Generalized Linear Models (GLMs) with time dependence (a.k.a. filters).

Proper citation: GLM utilities (RRID:SCR_027862) Copy   

•   Source: SciCrunch Registry

https://www.vai.org/research/core-services/spatial-collaborative-services/

Spatial Collaborative Services combines expertise and technology from VAIs Genomics Core and Optical Imaging Core to offer investigators a seamless pipeline for spatial imaging. Services include consultation, histology preparation, sequencing and imaging based spatial platforms.

Proper citation: Van Andel Institute Spatial Collaborative Services Core Facility (RRID:SCR_027861) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/research/core/medical-sculpture.php

Department of Medical Illustration’s Medical Sculpture Core advances education and research capabilities in medical sculpture. The space serves as an AU Core Research Lab to provide expertise in medical sculpture, volumetric visualization, and 3D printing. This lab space will offer educational and research opportunities for students to develop medical models such as surgical simulation models and patient education models. The research will improve surgical and medical training and provide insight into materials and technology to improve patient care.

Proper citation: Augusta University Medical Sculpture Core Facility (RRID:SCR_027863) Copy   

•   Source: SciCrunch Registry

https://docs.gspread.org/en/latest/

Software python library for working with Google Sheets allowing users to open spreadsheet by title, key or URL. It also allows to read, write, and format cell ranges and more.

Proper citation: gspread (RRID:SCR_027866) Copy   

•   Source: SciCrunch Registry

https://mic.massgeneralbrigham.org

Core facility that provides microscopy training, imaging solutions, image processing and analysis services, and consultation. Offers imaging techniques and expertise, including spinning disc confocal microscopy, two-photon confocal microscopy, super resolution microscopy, total internal reflection microscopy, wide field microscopy, fluorescence spectroscopy, photo-manipulation techniques (e.g. FRAP, photoablation, optogenetics, and optical tweezers) and live cell imaging.

Proper citation: Massachusetts General Hospital Brigham Center of Excellence for Molecular Imaging Core Facility (RRID:SCR_027865) Copy   

•   Source: SciCrunch Registry

https://mcity.umich.edu/

Core for building and testing mobility innovation is part of the University of Michigan Transportation Research Institute. Helps advance safe and efficient transportation and mobility solutions. Makerspace for mobility and transportation innovators. Offers open-source tools, remote or on-site testing.

Proper citation: University of Michigan MCity Core Facility (RRID:SCR_027857) Copy   

•   Source: SciCrunch Registry

https://github.com/NOW-Lab/STICR

Code to conduct combinatorial barcoding. scRNA-seq-compatible tracer for identifying clonal relationships.

Proper citation: STICR (RRID:SCR_027856) Copy   

•   Source: SciCrunch Registry

https://github.com/blaserlab/blaseRtools/tree/v0.0.0.9202

Software R tools for Blaser Lab Data Analysis. Package includes commonly used functions for R analysis in the Blaser Lab.

Proper citation: blaseRtools (RRID:SCR_027871) Copy   

•   Source: SciCrunch Registry

http://www.mtu.edu/mcff

Core facility provides tools for imaging, analysis, environmental testing, and micro/nanofabrication. Offers data, expertise, and hands-on training. From advanced materials to environmental systems, MCFF is the hub where discovery meets precision.

Proper citation: Michigan Technological University Materials Characterization and Fabrication Core Facility (RRID:SCR_027872) Copy   

•   Source: SciCrunch Registry

https://sourceforge.net/projects/sivic/

Software framework and application suite for processing and visualization of DICOM MR Spectroscopy data. Through the use of DICOM, SIVIC aims to facilitate the application of MRS in medical imaging studies.

Proper citation: Spectroscopic Imaging, VIsualization, and Computing (SIVIC) (RRID:SCR_027875) Copy   

•   Source: SciCrunch Registry

https://purr.purdue.edu

Provides online, collaborative working space and data-sharing platform. Provides services with data management planning, boilerplate text for proposal, sample plans and individual consultation. Each dataset gets DOI. PURR publishes and archives digital datasets from researchers across campus and welcomes all kinds of open data from images and videos to spreadsheets and source code.

Proper citation: Purdue University Research Repository (PURR) (RRID:SCR_027877) Copy   

•   Source: SciCrunch Registry