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http://tumormetrics.org/

Core facility that provides the following services: Reporting and database management service of radiological data for clinical trials, Radiologic exam quality control service.

The mission of the Tumor Imaging Metrics Core (TIMC) is to provide standardized, consistent, longitudinal radiological measurements to evaluate therapeutic response for DF/HCC clinical trials. The TIMC - * Makes reliable, quantitative, longitudinal measurements (such as RECIST, WHO, SWOG, standardized uptake value (SUV) etc.) of lesions from serial MRI, CT, PET, and PET/CT scan images * Presents results of analyses on a password-protected secure web-based report * Provides an independent service, with verifiable measurement of treatment response for patients enrolled in cancer center trials * Serves as a centralized, computerized resource to facilitate efficient internal or external auditing Reliable tracking of changes in lesion size or metabolism is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Imaging Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.

Proper citation: DF/HCC Tumor Imaging Metrics Core Facility (RRID:SCR_009744) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5de9-9aff-55da-381e80000000

Core facility that provides the following services: Histopathology analysis service, Histopathologic diagnosis training service, Cryosectioning service, Rodent necropsy service, Paraffin sectioning service, Bacteria, fungi, and inclusion bodies histological staining service, Rodent tissue processing, Carbohydrate and mucoproteins histological staining service, Connective tissue and muscle histological staining service, Cytoplasmic granules histological staining service, Fats and lipids histological staining service, Hematologic and nuclear elements histological staining service, Nerve cells and fibers histological staining service, Equipment training service, Equipment access service.

The Rodent Histopathology Core was founded in 1999 as one of the pathology cores within the Dana-Farber/Harvard Cancer Center. The Core was established to provide high quality professional, technical, and educational pathology services. The ultimate goal of the facility has been to support investigator research that leads to the identification of pathologic processes in mice and can be directly translatable to human disease. The core provides an essential and unique service to the many Center members and labs invested in mouse research. While many commercial and academic histology services are available, no other service is available that offers comparable high quality service with rapid turn around time and highly experienced professional supervision. The educational mission of the Core also adds an important dimension.

Proper citation: DF/HCC Rodent Histopathology Core Facility (RRID:SCR_009742) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-9c6c-06ee-55da-381e80000000

PSL is a consultative Core with components in each of the five DF/HCC hospitals. We have established a web-based network of autonomous, distributed, searchable databases, which contain de-identified, coded, pathologic information on post-diagnostic, excess human materials (including frozen or paraffin-embedded tissues and bodily fluids). Standardized specimen core dataset includes age, gender, anatomic location, tissue type, and diagnoses. Access to the PSL is through the password-protected Harvard eCommons. Two types of generic PSL uses are envisioned: (1) Center members with eCommons accounts can quickly retrieve aggregated tissue availability information to determine the feasibility of a proposed study. (2) Approved investigators can discover and review materials from suitable, de-identified and coded cases online and then request the samples they want.

Proper citation: DF/HCC Pathology Specimen Locator (RRID:SCR_009741) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c3-845c-db6e-7a3f80000000

Core facility that provides the following services: Soft-lithography service, Soft-lithography training and consultation.

The HMS Microfluidics Facility aims to make the tools of Microfabrication and Microfluidics available to all HMS users.

Proper citation: HMS Microfluidics Core Facility (RRID:SCR_009801) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-0219-d555-b2b9-4d8780000000

Core facility that provides the following services: Clinical diagnosis services, Genomic sequencing service, ABI capillary sequencing service, Illumina next generation sequencing service, shRNA library sequencing service, High throughput genome sequencing, PCR to detection service, Plasmid sequencing service, Sequencing, Chip-Seq service, Digital Gene Expression Service, Nucleic acid library construction service, Next gen seq bioinformatics support service, Transcriptome and RNA-Seq service.

Proper citation: Harvard PCPGM DNA Sequencing Facility (RRID:SCR_009858) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000135-5ed7-550c-be1e-73c480000000

The Small Molecule Mass Spectrometry Facility at the FAS Center for Systems Biology offers support for the analysis of a wide variety of analytes using mass spectrometry based techniques. We are located in the second basement (B2) level of the Northwest Laboratory building at 52 Oxford Street, Cambridge, MA 02138. We provide services for molecular formula confirmation (accurate mass measurement), structural elucidation (MS/MS) and quantitation of small molecules. In addition, we can assist you in the mass analysis of a wide variety of non-proteomics samples including metabolites, medium sized proteins and oligonucleotides. Please contact us and tell us about your samples prior to submission or use of our Open Access laboratory.

Proper citation: Harvard FAS Small Molecule Mass Spectrometry Facility (RRID:SCR_009845) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a1a6-4291-55da-381e80000000

Core facility that provides the following services: Progamming and sequencing classes and training. Research Computing (RC) facilitates the advancement of complex research by providing leading edge computing services across the Faculty of Arts & Sciences (FAS). RC staff maintain expertise in constantly changing computing technologies, while ''speaking the language'' of the FAS researchers, to help them use computing more effectively.

Proper citation: Harvard FAS Research Computing Core (RRID:SCR_009844) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9eb-c410-de5a-673e80000000

The Neuroimaging facility has a 3-Tesla magnetic resonance imaging scanner for non-invasive human brain imaging. Our aim is to: * Provide functional and anatomic magnetic resonance imaging (MRI) to scientists studying human cognition, brain development and aging, and individual differences * Provide training for undergraduate and graduate students destined to become the next generation of neuroscientists * Pioneer innovative ways of imaging the human brain and is a first adopter of new neuroimaging technology, tools and applications * Develop and make available the data processing and visualization tools demanded by advancing neuroimaging technologies.

Proper citation: Harvard FAS Center for Brain Science - Neuroimaging Core Facility (RRID:SCR_009842) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9ed-31bd-de5a-673e80000000

CBS hosts an optical imaging facility that houses advanced devices for widespread use by neuroscientists and is developing the next generation of optical techniques. The optical imaging is intended to be an extension of individual labs, housed in shared space. By pooling equipment, highly skilled technical management of the tools is available, allowing for routine technological upgrades, quicker troubleshooting, and expert advice. In addition, the joint space leads to camaraderie amongst users, and allows new technical advances in one lab to spread rapidly to other labs. This core facility also frees up space in individual labs that can be used in other ways. Finally, the shared equipment lowers barriers to adoption of the latest technology. This core facility provides: * Laser scanning microscopes with motorized stages for high throughput reconstructions of the nervous system * A histology suite for brain sectioning and tissue preparation * Stereo fluorescence macroscopes * The newest tools for high-resolution optical microscopy * Ultra-fast optical scanning microscopes

Proper citation: Harvard FAS Center for Brain Science - Imaging Core Facility (RRID:SCR_009840) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9f0-3cf3-de5a-673e80000000

CBS houses a core facility with a transmission electron microscope (TEM) and several scanning electron microscopes. The SEMs are part of ongoing research that will lead to a three-dimensional electron microscopy facility, to image neural circuits with the highest possible resolution.

Proper citation: Harvard FAS Center for Brain Science - Electron Microscopy Core Facility (RRID:SCR_009838) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5e6d-9119-55da-381e80000000

The Flow and Imaging Cytometry Resource provides research flow and imaging cytometry services to all investigators in the PCIMM at Children''s Hospital, Boston and Immune Disease Institute, HMS and the local scientific community on a case-by-case basis. With state of the art instrumentation, such as the standard configuration 3-lasers FACSAria located in BL2+-facility, 20-parameters 4-lasers FACSAria SORP and DIVA FACSVantage SE TurboSort?, the facility offers high speed cell sorting and complex analytical services, development of collaborative projects as well as consulting on design and development of new protocols and methods.

Proper citation: Harvard PCMM Flow and Imaging Cytometry Resource (RRID:SCR_009839) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-0220-1cee-b2b9-4d8780000000

Core facility that provides the following services: Illumina Gene Expression, Affymetrix gene expression. The Partners HealthCare Center for Personalized Genetic Medicine Microarray Facility is a full service facility dedicated to providing analysis for DNA or RNA samples. We provide support for high density microarrays to the Harvard Partners research community, including Harvard medical School, hospitals in the Partners Healthcare network, investigators in the Dana-Farber/Harvard Cancer Center, and the Harvard School of Public Health. Our services are open to both the PHS and non-PHS community.

Proper citation: Harvard PCPGM Microarray Facility (RRID:SCR_009860) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu/core-b

Core facility that provides service for paraffin embedding, sectioning, staining, and frozen sectioning; shared equipment and service for confocal, widefield, photodocumentation, electron microscopy, and digital image processing; and an immunostaining service.

Proper citation: Harvard Digestive Diseases Center Biomedical CORE B: Microscopy and Histopathology (RRID:SCR_009836) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c2-c99a-db6e-7a3f80000000

Core facility that provides the following services: Use of instruments service, Training service. The Harvard Center for Biological Imaging (HCBI) has been created to foster collaborative research in the most state-of-the-art facility available. To do this, we have set up a unique partnership with Carl Zeiss International in which our microscopy systems are continually replaced every 2-3 years ensuring we always have the most up-to-date equipment possible. The facility is open 24 hours/day, 7 days/week and access to the facility is open to all Harvard investigators as well as to affiliates and investigators from collaborating institutions.

Proper citation: Harvard Center for Biological Imaging (RRID:SCR_009834) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000130-7571-ee45-1971-4f2080000000

Center for Nanoscale Systems facility dealing with FIB, XPS, AFM, Optical Microscopy and Spectroscopy, Biomaterials, Soft Lithography, Microfluidics, Nano Particles, Chemical Nanotechnology, etc.

Proper citation: Harvard CNS Nanomaterial Facility (RRID:SCR_009833) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000139-928e-36d0-f016-703c80000000

The Biostatistics Core serves the needs of the HIV/AIDS researchers within the Ragon Institute and its affiliates. In particular, members of the Biostatistics Core provide expertise in the planning, conduct and analysis of research with the goal of enhancing the scientific quality of HIV-related research at the institute. The primary objective of the core is to ensure that studies are well designed, correctly analyzed, clearly presented, and correctly interpreted.

Proper citation: Ragon Institute Biostatistics Core (RRID:SCR_010055) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5eed-e0fd-55da-381e80000000

Core facility that provides the following services: Coulter XL flow analysis, Cytomation MoFlo cell sorting, LaserScan Cytometry, BD Biosciences LSR II flow cytometry analysis, Flow cytometry data analysis. The Flow Cytometry Facility is a core facility of Schepens Eye Research Institute that provides fluorescent-based cell analysis and sorting to Boston area biomedical researchers.

Proper citation: SERI Flow Cytometry Core Facility (RRID:SCR_010059) Copy   

•   Source: SciCrunch Registry

https://www.tissue-atlas.org/

Gathers together imaging and omic datasets into molecular maps of normal and diseased tissue from human and animal models, with emphasis on cancer. Used to access datasets, educational curriculum and talks, and recommended methods and software.

Proper citation: Harvard Tissue Atlas (RRID:SCR_022829) Copy   

•   Source: SciCrunch Registry

https://www.dfhcc.harvard.edu/research/core-facilities/tumor-imaging-metrics

Core provides centralized, standardized, accurate, consistent, and timely longitudinal, multimodality anatomic, volumetric and functional tumor metrics including CT, MR, PET/CT and other nuclear medicine imaging studies to evaluate therapeutic response for patients enrolled in DF/HCC oncologic clinical trials. TIMC supports more than 30 tumor response assessment criteria including but not limited to RECIST 1.1, iRECIST, Lugano, LYRIC, IWCLL and RANO. Results of tumor metric analyses are offered on password-protected secure web-based report.

Proper citation: Harvard Tumor Imaging Metrics Core Facility (RRID:SCR_012298) Copy   

•   Source: SciCrunch Registry

http://www.schepens.harvard.edu/graphics

Core facility that provides the following services: Web and graphic services, Web design and content management service, Photography service. Peter Mallen is a designer and illustrator who manages a full-service web and graphics studio in a moderately sized scientific research facility, Schepens Eye Research Institute. He provides a full range of graphic design, scientific illustration, web design and development, content management, and general design and production services. His products are utilized by: faculty and scientific staff (books, scientific publications, slide shows, grant applications); professional staff (Administration, Development & Public Affairs; brochures, books, pamphlets); the general public (Institute websites) as well as clients of our 250-seat state-of-the-art conference center, Starr Center for Scientific Communications.

Proper citation: Harvard SERI Graphic Services Core (RRID:SCR_012309) Copy   

•   Source: SciCrunch Registry