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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
MDQC
 
Resource Report
Resource Website
MDQC (RRID:SCR_001352) MDQC software resource A multivariate quality assessment software for microarrays based on quality control (QC) reports. The Mahalanobis distance of an array's quality attributes is used to measure the similarity of the quality of that array against the quality of the other arrays. Then, arrays with unusually high distances can be flagged as potentially low-quality. microarray, quality control is listed by: OMICtools
has parent organization: Bioconductor
PMID:17933854 Free, Available for download, Freely available OMICS_01987 SCR_001352 SciCrunch Registry Mahalanobis Distance Quality Control for microarrays 2026-10-17 01:24:53 0
MACAT
 
Resource Report
Resource Website
MACAT (RRID:SCR_001350) MACAT software resource Software library that contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. It is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions. differential expression, microarray, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:15572464 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01989, biotools:macat https://bio.tools/macat SCR_001350 SciCrunch Registry MicroArray Chromosome Analysis Tool 2026-10-17 01:24:58 0
nnNorm
 
Resource Report
Resource Website
nnNorm (RRID:SCR_001354) nnNorm software resource Software package that allows to detect and correct for spatial and intensity biases with two-channel microarray data. The normalization method implemented in this package is based on robust neural networks fitting. microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01985 SCR_001354 SciCrunch Registry nnNorm - Spatial and intensity based normalization of cDNA microarray data based on robust neural nets 2026-10-17 01:24:58 0
maCorrPlot
 
Resource Report
Resource Website
1+ mentions
maCorrPlot (RRID:SCR_001348) maCorrPlot software resource Software that graphically displays correlation in microarray data that is due to insufficient normalization. microarray, preprocessing, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:15799785 Free, Available for download, Freely available OMICS_01991 SCR_001348 SciCrunch Registry maCorrPlot - Visualize artificial correlation in microarray data 2026-10-17 01:24:53 2
lapmix
 
Resource Report
Resource Website
lapmix (RRID:SCR_001347) lapmix software resource Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes. differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:lapmix, OMICS_01992 https://bio.tools/lapmix SCR_001347 SciCrunch Registry Laplace Mixture Model in Microarray Experiments 2026-10-17 01:25:08 0
OCplus
 
Resource Report
Resource Website
1+ mentions
OCplus (RRID:SCR_001342) OCplus software resource Software package that allows to characterize the operating characteristics of a microarray experiment, i.e. the trade-off between false discovery rate and the power to detect truly regulated genes. The package includes tools both for planned experiments (for sample size assessment) and for already collected data (identification of differentially expressed genes). differential expression, microarray, multiple comparison is listed by: OMICtools
has parent organization: Bioconductor
PMID:16368770 Free, Available for download, Freely available OMICS_01999 SCR_001342 SciCrunch Registry Ocplus - Operating characteristics plus sample size and local fdr for microarray experiments 2026-10-17 01:24:58 1
bridge
 
Resource Report
Resource Website
100+ mentions
bridge (RRID:SCR_001343) bridge software resource Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space. cdna microarray, affymetrix chip, differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:16542223 Free, Available for download, Freely available OMICS_01996, biotools:bridge http://www.bioconductor.org/packages/release/bioc/html/bridge.html SCR_001343 SciCrunch Registry Bayesian Robust Inference for Differential Gene Expression 2026-10-17 01:25:08 157
CALIB
 
Resource Report
Resource Website
100+ mentions
CALIB (RRID:SCR_001338) CALIB software resource Software package that contains functions for normalizing spotted microarray data, based on a physically motivated calibration model. The model parameters and error distributions are estimated from external control spikes. microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
PMID:17485432 Free, Available for download, Freely available OMICS_02003 http://www.bioconductor.org/packages/release/bioc/html/CALIB.html SCR_001338 SciCrunch Registry 2026-10-17 01:24:58 141
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 SciCrunch Registry vsn - Variance stabilization and calibration for microarray data 2026-10-17 01:25:00 6
LPE
 
Resource Report
Resource Website
LPE (RRID:SCR_001364) LPE software resource Software library used to do significance analysis of microarray data with small number of replicates. It uses resampling based FDR adjustment, and gives less conservative results than traditional "BH" or "BY" procedures. Data accepted is raw data in txt format from MAS4, MAS5 or dChip. Data can also be supplied after normalization. LPE library is primarily used for analyzing data between two conditions. differential expression, microarray is listed by: OMICtools
has parent organization: Bioconductor
PMID:18450812 Free, Available for download, Freely available OMICS_01978 SCR_001364 SciCrunch Registry Local Pooled Error 2026-10-17 01:24:59 0
aroma.light
 
Resource Report
Resource Website
1+ mentions
aroma.light (RRID:SCR_001312) aroma.light software resource Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes. infrastructure, microarray, preprocessing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
DOI:10.1186/1471-2105-11-245 Free, Available for download, Freely available OMICS_01998, biotools:aroma.light https://bio.tools/aroma.light, https://sources.debian.org/src/r-bioc-aroma.light/ SCR_001312 SciCrunch Registry 2026-10-17 01:25:06 1
BeadDataPackR
 
Resource Report
Resource Website
BeadDataPackR (RRID:SCR_001310) BeadDataPackR software resource Software that provides functionality for the compression and decompression of raw bead-level data from the Illumina BeadArray platform. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:20981138 Free, Available for download, Freely available biotools:beaddatapackr, OMICS_02023 https://bio.tools/beaddatapackr SCR_001310 SciCrunch Registry BeadDataPackR - Compression of Illumina BeadArray data 2026-10-17 01:24:57 0
OLIN
 
Resource Report
Resource Website
10+ mentions
OLIN (RRID:SCR_001304) OLIN software resource Software functions for normalization of two-color microarrays by optimised local regression and for detection of artifacts in microarray data. r, normalization, visualization, quality control, two-channel, microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:15585527 Free, Available for download, Freely available biotools:olin, OMICS_02029 http://itb.biologie.hu-berlin.de/~futschik/software/R/OLIN/index.html SCR_001304 SciCrunch Registry Optimised Local Intensity-dependent Normalisation 2026-10-17 01:24:52 18
qcmetrics
 
Resource Report
Resource Website
1+ mentions
qcmetrics (RRID:SCR_001303) qcmetrics software resource Software package that provides a framework for generic quality control of data. It permits to create, manage and visualise individual or sets of quality control metrics and generate quality control reports in various formats. mass spectrometry, microarray, proteomics, quality control, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02032, biotools:qcmetrics, BioTools:qcmetrics https://bio.tools/qcmetrics, https://bio.tools/qcmetrics, https://bio.tools/qcmetrics SCR_001303 SciCrunch Registry qcmetrics - A Framework for Quality Control 2026-10-17 01:25:06 1
DEXUS
 
Resource Report
Resource Website
1+ mentions
DEXUS (RRID:SCR_001309) DEXUS software resource Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power. classification, differential expression, gene expression, hapmap, quality control, rna-seq, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24049071 Free, Available for download, Freely available biotools:dexus, OMICS_02024 http://www.bioconductor.org/packages/release/bioc/html/dexus.html SCR_001309 SciCrunch Registry DEXUS - Identifying Differential Expression in RNA-Seq Studies with Unknown Conditions or without Replicates 2026-10-17 01:24:52 1
HEM
 
Resource Report
Resource Website
HEM (RRID:SCR_000194) HEM software resource Software package that fits heterogeneous error models for analysis of microarray data differential expression, microarray is listed by: OMICtools
has parent organization: Bioconductor
has parent organization: University of Virginia; Virginia; USA
PMID:15044230 Free, Available for download, Freely available OMICS_01970 SCR_000194 SciCrunch Registry HEM - Heterogeneous error model for identification of differentially expressed genes under multiple conditions 2026-10-17 01:24:34 0
DESeq
 
Resource Report
Resource Website
500+ mentions
DESeq (RRID:SCR_000154) DESeq data analysis software, data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression. gene expression, binomial, differential, negative binomial distribution, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is hosted by: Bioconductor
PMID:20979621
DOI:10.1186/s13059-014-0550-8
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01306, biotools:deseq https://bio.tools/deseq, https://sources.debian.org/src/r-bioc-deseq2/ SCR_000154 SciCrunch Registry 2026-10-17 01:24:33 529
MIMOSA
 
Resource Report
Resource Website
MIMOSA (RRID:SCR_000184) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software for modeling count data using Dirichlet-multinomial and beta-binomial mixtures with applications to single-cell assays. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23887981 THIS RESOURCE IS NO LONGER IN SERVICE biotools:mimosa, OMICS_05642 https://bio.tools/mimosa SCR_000184 SciCrunch Registry MIMOSA - Mixture Models for Single-Cell Assays, MIMOSA: Mixture Models For Single Cell Assays 2026-10-17 01:24:34 0
iASeq
 
Resource Report
Resource Website
iASeq (RRID:SCR_000420) software resource Software that uses a Bayesian hierarchical mixture model to learn correlation patterns of allele-specificity among multiple proteins. software package, unix/linux, mac os x, windows, r, chip-seq, rna-seq, snp is listed by: OMICtools
has parent organization: Bioconductor
PMID:23194258 Free, Available for download, Freely available OMICS_05505 SCR_000420 SciCrunch Registry iASeq: integrating multiple sequencing datasets for detecting allele-specific events 2026-10-17 01:24:43 0
rTANDEM
 
Resource Report
Resource Website
rTANDEM (RRID:SCR_000409) software resource An R/Bioconductor package that interfaces the X!Tandem protein identification algorithm. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics is used by: shinyTANDEM
is listed by: OMICtools
has parent organization: Bioconductor
PMID:24700319 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_03516 SCR_000409 SciCrunch Registry rTANDEM - Interfaces the tandem protein identification algorithm in R 2026-10-17 01:24:40 0

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