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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
spliceR
 
Resource Report
Resource Website
10+ mentions
spliceR (RRID:SCR_002280) software resource An easy-to-use R package for classification of alternative splicing and prediction of coding potential from RNA-seq data. standalone software, unix/linux, mac os x, windows, c, r, differential expression, high throughput sequencing, rna-seq, rna-seq, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:24655717 GNU General Public License, v2 or greater OMICS_03514 SCR_002280 spliceR - Classification of alternative splicing and prediction of coding potential from RNA-seq data 2026-09-05 06:24:46 25
flowPlots
 
Resource Report
Resource Website
flowPlots (RRID:SCR_002177) software resource Software for analysis plots and data class for gated flow cytometry data. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, data representation, visualization is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_05608 SCR_002177 flowPlots: analysis plots and data class for gated flow cytometry data 2026-09-05 06:24:44 0
metaRNASeq
 
Resource Report
Resource Website
10+ mentions
metaRNASeq (RRID:SCR_002174) software resource Software package for meta-analysis of RNA-seq data. This package implements two p-value combination techniques (inverse normal and Fisher methods). It also provides a vignette explaining how to combine data from multiple RNA-seq experiments. standalone software, unix/linux, mac os x, windows, r is listed by: OMICtools
is related to: SMAGEXP
has parent organization: CRAN
PMID:24678608 Free, Available for download, Freely available OMICS_03527 SCR_002174 metaRNASeq: Meta-analysis of RNA-seq data 2026-09-05 06:24:44 35
DEMI
 
Resource Report
Resource Website
1+ mentions
DEMI (RRID:SCR_002291) software resource R package for estimating differential expression from multiple indicators that capitalizes on the high number of concurrent measurements. It extends to various experimental designs and target categories (transcripts, genes, genomic regions) as well as small sample sizes. standalone software, affymetrix, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:24586062 Free, Available for download, Freely available, Acknowledgement requested OMICS_03438 http://cran.r-project.org/web/packages/demi/ SCR_002291 demi: Differential Expression from Multiple Indicators, Differential Expression from Multiple Indicators 2026-09-05 06:24:46 6
flowCore
 
Resource Report
Resource Website
100+ mentions
flowCore (RRID:SCR_002205) software resource A Bioconductor software package for high throughput flow cytometry that provides S4 data structures and basic functions. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, infrastructure is used by: flowBeads
is listed by: OMICtools
has parent organization: Bioconductor
PMID:19358741 Artistic License, v2 OMICS_05596 SCR_002205 flowCore: Basic structures for flow cytometry data 2026-09-05 06:24:45 376
flowBeads
 
Resource Report
Resource Website
flowBeads (RRID:SCR_002440) software resource Software package for the analysis of flow cytometry bead data. It extends flowCore to provide functionality specific to bead data. One of the goals of this package is to automate analysis of bead data for the purpose of normalization. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, infrastructure uses: flowCore
is listed by: OMICtools
has parent organization: Bioconductor
Free, Freely available OMICS_05592 SCR_002440 flowBeads: Analysis of flow bead data 2026-09-05 06:24:48 0
flowCyBar
 
Resource Report
Resource Website
1+ mentions
flowCyBar (RRID:SCR_002319) software resource A software package to analyze flow cytometric data using gate information to follow population / community dynamics. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, clustering, visualization is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 OMICS_05597 SCR_002319 flowCyBar - Analyze flow cytometric data using gate information 2026-09-05 06:24:46 7
MBASED
 
Resource Report
Resource Website
10+ mentions
MBASED (RRID:SCR_002584) software resource Software package containing functions for allele-specific gene expression (ASE) analysis using meta-analysis based allele-specific expression detection. software package, unix/linux, mac os x, windows, r, gene expression, sequencing, transcription is listed by: OMICtools
has parent organization: Bioconductor
PMID:25315065 Free, Available for download, Freely available OMICS_05502 http://www.bioconductor.org/packages/release/bioc/html/MBASED.html SCR_002584 Meta-analysis Based Allele-Specific Expression Detection, MBASED - Package containing functions for ASE analysis using Meta-analysis Based Allele-Specific Expression Detection 2026-09-05 06:24:50 17
DSS
 
Resource Report
Resource Website
1+ mentions
DSS (RRID:SCR_002754) software library, software resource, software toolkit Software R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions. standalone software, unix/linux, mac os x, windows, r, differential expression, rna-seq, chip-seq, dna methylation, differential expression, sequencing is listed by: OMICtools
has parent organization: Bioconductor
PMID:24561809 Free, Freely available, Available for download OMICS_03273 SCR_002754 Dispersion Shrinakge for Sequencing data, DSS - Dispersion shrinakge for sequencing data 2026-09-05 06:24:53 9
rBiopaxParser
 
Resource Report
Resource Website
1+ mentions
rBiopaxParser (RRID:SCR_002744) software resource A software package that provides a comprehensive set of functions for parsing, viewing and modifying BioPAX pathway data within R. At the moment BioPAX level 2 and level 3 are supported. software package, mac os x, unix/linux, windows, data representation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23274212 Free, Freely available, Available for download biotools:rbiopaxparser, OMICS_05211 https://github.com/frankkramer/rBiopaxParser, https://bio.tools/rbiopaxparser SCR_002744 rBiopaxParser - Parses BioPax files and represents them in R 2026-09-05 06:24:53 4
DMRforPairs
 
Resource Report
Resource Website
1+ mentions
DMRforPairs (RRID:SCR_005702) software resource Software for identifying differentially methylated regions between unique samples using array based methylation profiles. It allows researchers to compare n greater than or equal to 2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishesit from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance. standalone software, mac os x, unix/linux, windows, r, annotation, dna methylation, differential methylation, microarray, report writing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24884391 GNU General Public License, v2 or greater biotools:dmrforpairs, OMICS_04059 https://bio.tools/dmrforpairs SCR_005702 DMR2+, DMRforPairs: identifying Differentially Methylated Regions between unique samples using array based methylation profiles 2026-09-05 06:25:40 4
Staden Package
 
Resource Report
Resource Website
50+ mentions
Staden Package (RRID:SCR_005629) software resource A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows. c, unix/linux, sequence assembly, dna/protein analysis, spin, sequence alignment, genome, genome viewer, c++, fortran, tcl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:20513662
DOI:10.1093/bioinformatics/btq268
BSD License OMICS_00894, biotools:staden https://bio.tools/staden, https://sources.debian.org/src/staden/ SCR_005629 Staden Package 2026-09-05 06:25:39 87
MetaQC
 
Resource Report
Resource Website
10+ mentions
MetaQC (RRID:SCR_006000) software resource Software for quality control and diagnosis for microarray meta-analysis. Quantitative quality control measures include: (1) internal homogeneity of co-expression structure among studies (internal quality control; IQC); (2) external consistency of co-expression structure correlating with pathway database (external quality control; EQC); (3) accuracy of differentially expressed gene detection (accuracy quality control; AQCg) or pathway identification (AQCp); (4) consistency of differential expression ranking in genes (consistency quality control; CQCg) or pathways (CQCp). For each quality control index, the p-values from statistical hypothesis testing are minus log transformed and PCA biplots were applied to assist visualization and decision. Results generate systematic suggestions to exclude problematic studies in microarray meta-analysis and potentially can be extended to GWAS or other types of genomic meta-analysis. The identified problematic studies can be scrutinized to identify technical and biological causes (e.g. sample size, platform, tissue collection, preprocessing etc) of their bad quality or irreproducibility for final inclusion / exclusion decision. standalone software, mac os x, unix/linux, windows, r, FASEB list is listed by: OMICtools
has parent organization: CRAN
PMID:22116060 GNU General Public License, v2 OMICS_04032 https://github.com/donkang34/MetaQC SCR_006000 MetaQC: Objective Quality Control and Inclusion/Exclusion Criteria for Genomic Meta-Analysis, MetaQC: Objective Quality Control and Inclusion / Exclusion Criteria for Genomic Meta-Analysis 2026-09-05 06:25:45 40
aCGH.Spline
 
Resource Report
Resource Website
aCGH.Spline (RRID:SCR_002927) software resource An R package for array comparative genomic hybridization (aCGH) dye bias normalization. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:21357574 Free, Available for download, Freely available OMICS_02607 http://cran.r-project.org/web/packages/aCGH.Spline/ SCR_002927 2026-09-05 06:24:55 0
Basic4Cseq
 
Resource Report
Resource Website
1+ mentions
Basic4Cseq (RRID:SCR_002836) software resource An R/Bioconductor package for basic filtering, analysis and subsequent near-cis visualization of 4C-seq data. Virtual fragment libraries can be created for any BSGenome package, and filter functions for both reads and fragments and basic quality controls are included. Fragment data in the vicinity of the experiment's viewpoint can be visualized as a coverage plot based on a running median approach and a multi-scale contact profile. software package, unix/linux, mac os x, windows, r, quality control, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:25078398 Free, Freely available, Available for download OMICS_05202 SCR_002836 Basic4Cseq: an R/Bioconductor package for analyzing 4C-seq data 2026-09-05 06:24:54 6
mzR
 
Resource Report
Resource Website
1+ mentions
mzR (RRID:SCR_002856) software resource Software that provides a unified API to the common file formats and parsers available for mass spectrometry data. It comes with a wrapper for the ISB random access parser for mass spectrometry mzXML, mzData and mzML files. standalone software, mac os x, unix/linux, windows, r, data import, infrastructure, mass spectrometry, metabolomics, proteomics is listed by: OMICtools
has parent organization: Bioconductor
Free, Freely available, Available for download OMICS_02654 SCR_002856 mzR - parser for netCDF mzXML mzData and mzML and mzIdentML files 2026-09-05 06:24:54 1
BiGGR
 
Resource Report
Resource Website
BiGGR (RRID:SCR_002854) software resource Software package that provides an interface to simulate metabolic reconstruction from the BiGG database and other metabolic reconstruction databases. The package facilitates flux balance analysis (FBA) and the sampling of feasible flux distributions. Metabolic networks and estimated fluxes can be visualized with hypergraphs. standalone software, mac os x, unix/linux, windows, r, metabolomics, network, visualization, metabolic reconstruction, model uses: BiGG Database
is listed by: OMICtools
has parent organization: Bioconductor
PMID:25806817 Free, Freely available, Available for download OMICS_02655 SCR_002854 BiGGR - Constraint based modeling in R using metabolic reconstruction databases 2026-09-05 06:24:54 0
PAPi
 
Resource Report
Resource Website
50+ mentions
PAPi (RRID:SCR_002857) software resource An R package for predicting the activity of metabolic pathways based solely on a metabolomics data set containing a list of metabolites identified and their respective abundances in different biological samples. PAPi generates hypothesis that improves the final biological interpretation. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics is listed by: OMICtools
has parent organization: Bioconductor
PMID:20929912 Free, Freely available, Available for download OMICS_02653 SCR_002857 PAPi - Predict metabolic pathway activity based on metabolomics data, Pathway Activity Profiling 2026-09-05 06:24:54 56
CNVassoc
 
Resource Report
Resource Website
1+ mentions
CNVassoc (RRID:SCR_002901) software resource Software package that carries out association analysis of common copy number variants in population-based studies. It includes functions for analysing association under a series of study designs (case-control, cohort, etc), using several dependent variables (class status, censored data, counts) as response, adjusting for covariates and considering various inheritance models. It also includes functions for inferring copy number (CNV genotype calling). Various classes and methods for generic functions (print, summary, plot, anova, ... ) have been created to facilitate the analysis. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:21609482 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02609 SCR_002901 CNVassoc: Association analysis of CNV data 2026-09-05 06:24:55 1
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-09-05 06:24:57 4

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