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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SimpleITK
 
Resource Report
Resource Website
50+ mentions
SimpleITK (RRID:SCR_024693) software library, software resource, software toolkit Open source software library for multi dimensional image analysis in Python, R, Java, C#, Lua, Ruby, TCL and C++. New interface to Insight Segmentation and Registration Toolkit (ITK) designed to facilitate rapid prototyping, education and scientific activities via high level programming languages. Provides easy to use and simplified interface to ITK's algorithms. multi dimensional image analysis, Insight Segmentation and Registration Toolkit, is related to: Insight Segmentation and Registration Toolkit NLM PMID:24416015 Free, Available for download, Freely available https://github.com/SimpleITK/SimpleITK SCR_024693 Simple Insight Segmentation and Registration Toolkit 2026-08-29 11:29:13 69
MedGen
 
Resource Report
Resource Website
1+ mentions
MedGen (RRID:SCR_000111) MedGen data or information resource, database A database of organized information related to human medical genetics, such as attributes of conditions with a genetic contribution. medical genetics, medical, genetics, disease, clinical is listed by: OMICtools
is listed by: Genetic Testing Registry
has parent organization: NCBI
NLM 1ZIHLM200888-05 PMID:32329672 nlx_156941, OMICS_01549 SCR_000111 2026-08-29 11:29:04 6
Automated Microarray Pipeline
 
Resource Report
Resource Website
Automated Microarray Pipeline (RRID:SCR_001219) AMP analysis service resource, data analysis service, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented November 4, 2015. Web application based on the TM4 Microarray Software Suite to provide a means of normalization and analysis of microarray data. Users can upload data in the form of Affymetrix CEL files, and define an analysis pipeline by selecting several intuitive options. It performs data normalization (eg RMA), basic statistical analysis (eg t-test, ANOVA), and analysis of annotation using gene classification (eg Gene Ontology term assignment). The analysis are performed without user intervention and the results are presented in a web-based summary that allows data to be downloaded in a variety of formats compatible with further directed analysis. microarray, normalization is listed by: OMICtools
is related to: Gene Ontology
has parent organization: TM4
NLM R01-LM008795 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02125 http://www.tm4.org/amp.html SCR_001219 TM4 AMP, AMP: Automated Microarray Pipeline, AMP (TM4 Microarray Software Suite), TM4 Microarray Software Suite: Automated Microarray Pipeline, TM4 Microarray Software Suite: AMP 2026-08-29 11:29:09 0
Alignable Tight Genomic Cluster
 
Resource Report
Resource Website
1+ mentions
Alignable Tight Genomic Cluster (RRID:SCR_001894) ATGC data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. ATGC stands for Alignable Tight Genomic Cluster, which is cluster of closely related prokaryotic genomes. ATGC is the principal notion of this web resource. The purpose of this web resource is to prepare ATGC-derived data sets for a variety of research projects in functional and evolutionary genomics. Unique features of ATGC include: * Reliable identification of orthologs (high degree of similarity between the genomes in the set allow an extensive use of synteny in ortholog identification); * Fine granularity of protein classification (in comparisons of more distant genomes, proteins belonging to families of paralogs are often lumped into a singlegroup; under the ATGC approach, comparison of genomic sequences from highly similar genomes allows one to track each set of orthologs separately); * Relative rarity of changes of any kind (in sequence, genome organization and gene content) allows the use of parsimony-related methods of analysis. gene, genomic cluster, genomic sequence, ortholog, paralog, prokaryotic genomic, protein, protein classification has parent organization: Lawrence Berkeley National Laboratory Department of Energy Joint Genome Institute ;
NLM ;
DOE DE-AC02-05CH11231
PMID:28053163
PMID:18845571
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02581 SCR_001894 2026-08-29 11:29:14 1
UniProt
 
Resource Report
Resource Website
10000+ mentions
UniProt (RRID:SCR_002380) UniProt data or information resource, database Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB. collection, protein, sequence, annotation, data, functional, information is used by: LIPID MAPS Proteome Database
is used by: ChannelPedia
is used by: Open PHACTS
is used by: DisGeNET
is used by: Smart Dictionary Lookup
is used by: MitoMiner
is used by: Cytokine Registry
is used by: MobiDB
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is used by: Phospho.ELM
is used by: GEROprotectors
is used by: SwissLipids
is recommended by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: LabWorm
is related to: Clustal W2
is related to: UniProt DAS
is related to: UniParc at the EBI
is related to: ProDom
is related to: LegumeIP
is related to: Pathway Commons
is related to: NIH Data Sharing Repositories
is related to: FlyMine
is related to: IMEx - The International Molecular Exchange Consortium
is related to: 3D-Interologs
is related to: Biomine
is related to: EBIMed
is related to: STOP
is related to: Coremine Medical
is related to: BioExtract
is related to: STRAP
is related to: GOTaxExplorer
is related to: GoAnnotator
is related to: IT-GOM: Integrated Tool for IC-based GO Semantic Similarity Measures
is related to: Whatizit
is related to: MOPED - Model Organism Protein Expression Database
is related to: Polbase
is related to: PredictSNP
is related to: PSICQUIC Registry
is related to: IntAct
is related to: p300db
is related to: UniProt Proteomes
is related to: SARS-CoV-2 mutation effects and 3D structure prediction from sequence covariation
has parent organization: European Bioinformatics Institute
has parent organization: SIB Swiss Institute of Bioinformatics
has parent organization: Protein Information Resource
is parent organization of: UniProtKB
is parent organization of: NEWT
is parent organization of: UniParc
is parent organization of: UniProt Chordata protein annotation program
is parent organization of: UniRef
works with: Genotate
works with: CellPhoneDB
works with: MOLEonline
works with: MiMeDB
ARUK ;
British Heart Foundation ;
EMBL ;
NCI ;
NCRR P20 RR016472;
NEI ;
NHGRI P41 HG02273;
NHGRI U24 HG007722;
NHGRI U41 HG006104;
NHLBI ;
NIAID ;
NIA ;
NIDDK ;
NIGMS 5R01GM080646;
NIGMS R01 GM080646;
NIMH ;
NLM G08 LM010720;
NSF DBI-0850319;
PDUK
PMID:19843607
PMID:18836194
PMID:18045787
PMID:17142230
PMID:16381842
PMID:15608167
PMID:14681372
nif-0000-00377, SCR_018750, r3d100010357 http://www.ebi.uniprot.org, http://www.uniprot.org/uniprot/, http://www.pir.uniprot.org, ftp://ftp.uniprot.org, https://doi.org/10.17616/R3BW2M SCR_002380 , The Universal Protein Resource, Universal Protein Resource, UNIPROT Universal Protein Resource 2026-08-29 11:29:17 19823
Directory of Health Organizations Online
 
Resource Report
Resource Website
1+ mentions
Directory of Health Organizations Online (RRID:SCR_002331) DIRLINE data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE, documented July 15, 2016. Database containing location and descriptive information about a wide variety of information resources including organizations, research resources, projects, and databases concerned with health and biomedicine. This information may not be readily available in bibliographic databases. Each record may contain information on the publications, holdings, and services provided. These information resources fall into many categories including federal, state, and local government agencies; information and referral centers; professional societies; self-help groups and voluntary associations; academic and research institutions and their programs; information systems and research facilities. Topics include HIV/AIDS, maternal and child health, most diseases and conditions including genetic and other rare diseases, health services research and technology assessment. DIRLINE can be searched using subject words (such as disease or condition) including Medical Subject Headings (MeSH) or for the name or location of a resource. It now offers an A to Z list of over 8,500 organizations. genetic, aids, biomedicine, child, condition, disease, health, hiv, maternal, medicine, public health has parent organization: National Library of Medicine NLM N01LM023524 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21122 SCR_002331 Directory of Information Resources Online 2026-08-29 11:29:23 1
DP-Bind: a web server for sequence-based prediction of DNA-binding residues in DNA-binding proteins
 
Resource Report
Resource Website
10+ mentions
DP-Bind: a web server for sequence-based prediction of DNA-binding residues in DNA-binding proteins (RRID:SCR_003039) DP-Bind analysis service resource, data analysis service, production service resource, service resource This web-server takes a user-supplied sequence of a DNA-binding protein and predicts residue positions involved in interactions with DNA. Prediction can be performed using a profile of evolutionary conservation of the input sequence automatically generated by the web-server or the input sequence alone. Three prediction methods are run for each input sequence and consensus prediction is generated. dna binding has parent organization: University at Albany; New York; USA NLM 1R03LM009034-01 PMID:17237068
PMID:16568445
Free, Freely available nif-0000-30426 SCR_003039 2026-08-29 11:29:26 20
Distant Regulatory Elements
 
Resource Report
Resource Website
10+ mentions
Distant Regulatory Elements (RRID:SCR_003058) DiRE analysis service resource, data analysis service, production service resource, service resource Web server based on the Enhancer Identification (EI) method, to determine the chromosomal location and functional characteristics of distant regulatory elements (REs) in higher eukaryotic genomes. The server uses gene co-expression data, comparative genomics, and combinatorics of transcription factor binding sites (TFBSs) to find TFBS-association signatures that can be used for discriminating specific regulatory functions. DiRE's unique feature is the detection of REs outside of proximal promoter regions, as it takes advantage of the full gene locus to conduct the search. DiRE can predict common REs for any set of input genes for which the user has prior knowledge of co-expression, co-function, or other biologically meaningful grouping. The server predicts function-specific REs consisting of clusters of specifically-associated TFBSs, and it also scores the association of individual TFs with the biological function shared by the group of input genes. Its integration with the Array2BIO server allows users to start their analysis with raw microarray expression data. regulatory element, enhancer identification, genome, prediction, transcription factor binding site, gene, co-expression, co-function, function, transcription factor, comparative genomics, regulatory function, gene locus, chromosome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: NCBI
NLM ;
Intramural Research Program
PMID:18487623 Free, Freely available nif-0000-30448, biotools:dire https://bio.tools/dire SCR_003058 Distant Regulatory Elements of co-regulated genes 2026-08-29 11:29:18 25
EVidenceModeler
 
Resource Report
Resource Website
1000+ mentions
EVidenceModeler (RRID:SCR_014659) EVM data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for automated eukaryotic gene structure annotation that reports eukaryotic gene structures as weighted consensus of all available evidence. Used to combine ab intio gene predictions and protein and transcript alignments into weighted consensus gene structures. Inputs include genome sequence, gene predictions, and alignment data (in GFF3 format). sequence analysis software, framework, ab intio gene, gene prediction, protein alignment, transcript alignment, consensus gene structure NIAID N01 AI30071;
NLM R01 LM006845
PMID:18190707 Free, Available for download, Freely available SCR_017649 SCR_014659 2026-08-29 11:27:39 1283
GLIMMPSE
 
Resource Report
Resource Website
1+ mentions
GLIMMPSE (RRID:SCR_016297) data analysis software, data processing software, software application, software resource Web based software tool that calculates power and sample size for study designs with normally distributed outcomes. Permits power calculations for clinical trials, randomized experiments, and observational studies with clustering, repeated measures, and both, and almost any testable hypothesis. GLIMMPSE Version 3 release back end has been refactored in Python, interface has been simplified, requiring user decisions about only one topic per screen, new menu improves specification of both between-participant and within-participant hypothese, recursive algorithm permits computing covariances for up to ten levels of clustering., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. power, multivariate, linear, models, Gaussian, error, Java, web, calculate NIGMS R01 GM121081;
NIGMS R25 GM111901;
NLM G13 LM011879
PMID:24403868
PMID:40901910
THIS RESOURCE IS NO LONGER IN SERVICE SCR_016297 , GLIMMPSE Version 3 2026-08-29 11:28:07 9
Anne O'Tate
 
Resource Report
Resource Website
1+ mentions
Anne O'Tate (RRID:SCR_023086) software resource, web application Web search tool to gain overview of set of articles retrieved by PubMed query. Used to support user driven summarization, drill down and browsing of PubMed search results. Value-added PubMed search engine for analysis and text mining. Value added PubMed search engine, analysis and text mining has parent organization: University of Illinois at Chicago; Illinois; USA NLM LM 007292;
NLM LM 08364
PMID:18279519
PMID:33684153
Free, Freely available SCR_023086 2026-08-29 11:28:14 1
RobotReviewer
 
Resource Report
Resource Website
1+ mentions
RobotReviewer (RRID:SCR_021064) software application, software resource, text-mining software, web application Open source web based system that uses machine learning and NLP to semi automate biomedical evidence synthesis, to aid practice of Evidence Based Medicine. Processes full text journal articles describing randomized controlled trials. Designed to automatically extract key data items from reports of clinical trials. Data automatic extraction, clinical trial reports, automatically extract key data, Evidence Based Medicine, text journal articles processing, randomized controlled trials is related to: Northeastern University; Massachusetts; USA
is related to: University of Texas at Austin; Texas; USA
Medical Research Council UK ;
NCI UH2 CA203711;
NLM R01 LM012086
PMID:29093610
DOI:10.1093/jamia/ocv044
Free, Available for download, Freely available https://github.com/ijmarshall/robotreviewer, https://robotreviewer.vortext.systems/ SCR_021064 Automating Biomedical Evidence Synthesis 2026-08-29 11:27:03 1
NCBI BioSample
 
Resource Report
Resource Website
100+ mentions
NCBI BioSample (RRID:SCR_004854) BioSample data or information resource, database Database containing descriptions of biological source materials used in experimental assays. Sources include: GenBank, Sequence Read Archive (SRA), Coriell, ATCC. Submissions are supported by a web-based Submission Portal that guides users through a series of forms for input of rich metadata describing their samples. As the capacity and complexity of biological data sets expands, databases face new challenges in ensuring that the information is adequately organized and described. The NCBI BioSample database is being developed to help address the challenges by providing the means by which data generators can organize and describe a broad range of sample types, and link to corresponding sets of experimental data in archival databases. RIN, Resource Information Network, dna, rna, cell, cell line, stem cell, biomaterial, gold standard, RRID Community Authority is listed by: OMICtools
is listed by: Resource Information Network
is related to: GenBank
is related to: BioSample Database at EBI
is related to: ATCC
is related to: NCBI Sequence Read Archive (SRA)
is related to: Coriell Cell Repositories
is related to: CannSeek Database of Cannabis sativa SNPs
has parent organization: NCBI
NLM PMID:22139929 The community can contribute to this resource nlx_143929, r3d100012828, OMICS_01024 https://doi.org/10.17616/R31NJME4 SCR_004854 BioSample Database, NCBI BioSample Database 2026-08-29 11:29:29 432
MUMmerGPU
 
Resource Report
Resource Website
1+ mentions
MUMmerGPU (RRID:SCR_001200) MUMmerGPU data processing software, software application, software resource Software tool as high throughput DNA sequence alignment program that runs on nVidia G80-class GPUs. Aligns sequences in parallel on video card to accelerate widely used serial CPU program MUMmer. parallel computation 4, high-throughput sequencing, sequence alignment, dna, graphics processing unit is listed by: OMICtools
is related to: MUMmer
has parent organization: SourceForge
has parent organization: University of Maryland; Maryland; USA
NIGMS R01 GM083873;
NLM R01 LM006845
PMID:20161021 Free, Available for download, Freely available OMICS_02151 SCR_001200 High-throughput sequence alignment using Graphics Processing Units 2026-08-29 11:28:32 5
NCBI Resource List
 
Resource Report
Resource Website
NCBI Resource List (RRID:SCR_005628) NCBI Resources data or information resource, organization portal, portal The National Center for Biotechnology Information''s listing of resources. Sort by alphabetical character, Databases, Downloads, Submissions, Tools and How-To; or by Topic: Chemicals & Bioassays; Data & Software; DNA & RNA; Domains & Structures; Genes & Expression; Genetics & Medicine; Genomes & Maps; Homology; Literature; Proteins; Sequence Analysis; Taxonomy; Training & Tutorials; Variation. database, download, submission, tool, chemical, bioassay, data, software, dna, rna, domain, structure, gene, expression, genetics, medicine, genomes, map, homology, literature, protein, sequence analysis, taxonomy, training, tutorial, variation, gold standard has parent organization: NCBI NLM nlx_146242 SCR_005628 NCBI Resource Guide, NCBI Resource List (A-Z) 2026-08-29 11:28:36 0
iPOP
 
Resource Report
Resource Website
10+ mentions
iPOP (RRID:SCR_008991) iPOP data or information resource, data set Data set generated by personal omics profiling of Dr. Michael Snyder at Stanford University. It combines genomic, transcriptomic, proteomic, metabolomic, and autoantibody profiles from a single individual over a 14 month period. The analysis revealed various medical risks, including type II diabetes. It also uncovered extensive, dynamic changes in diverse molecular components and biological pathways across healthy and diseased conditions. genomics, proteomics, transcriptional profiling, saliva, blood, maternal data, metabolomics, personalized medicine, adult human, genetics, transcriptome, male has parent organization: Stanford University; Stanford; California Healthy Breetwor Family Foundation ;
Korber Foundation ;
Fundacion Marcelino Botin ;
Fundacion Lilly ;
NLM T15-LM007033;
NIGMS R24-GM61374;
NHLBI T32 HL094274;
NHLBI KO8 HL083914;
NIH New Investigator DP2 award OD004613;
Spanish Ministry of Science and Innovation Projects ;
Spanish Ministry of Science and Innovation Projects ;
European Union FP7 Genica ;
European Union FP7 TELOMARKER ;
European Research Council Advanced Grant
PMID:22424236 Free for personal, Non-exclusive, Non-transferable, Non-commercial access., Please cite. nlx_152492 SCR_008991 Snyderome, Integrated Personal Omics Profiling 2026-08-29 11:31:55 14
SpikeHunter
 
Resource Report
Resource Website
1+ mentions
SpikeHunter (RRID:SCR_024831) data analysis software, data processing software, sequence analysis software, software application, software resource Software deep learning tool for identifying phage tailspike proteins. Used to identify phage tailspike proteins. identifying phage tailspike proteins, phage tailspike protein, deplolymerase, right-handed beta-helix, NLM ;
NSF
PMID:37503040 Free, Available for download, Freely available SCR_024831 2026-08-29 11:33:34 1
Penn machine learning benchmark repository
 
Resource Report
Resource Website
Penn machine learning benchmark repository (RRID:SCR_017138) PMLB data or information resource, data set Python wrapper for Penn Machine Learning Benchmark data repository. Large, curated repository of benchmark datasets for evaluating supervised machine learning algorithms. Part of PyPI https://pypi.org/ benchmark, suite, machine, learning, evaluation, comparison, repository, curated, dataset NCATS TR001263;
NEI EY022300;
NHLBI HL134015;
NIAID AI116794;
NIDDK DK112217;
NIEHS ES013508;
NLM LM009012;
NLM LM010098;
NLM LM011360;
Warren Center for Network and Data Science
PMID:29238404 Free, Restricted https://github.com/EpistasisLab/penn-ml-benchmarks SCR_017138 Penn Machine Learning Benchmark 2026-08-29 11:33:15 0
ReBATE
 
Resource Report
Resource Website
ReBATE (RRID:SCR_017139) software resource, software toolkit Open source software Python package to compare relief based feature selection algorithms used in data mining. Used for feature selection in any bioinformatics problem with potentially predictive features and target outcome variable, to detect feature interactions without examination of all feature combinations, to detect features involved in heterogeneous patterns of association such as genetic heterogeneity . compare, relief, feature, algorithm, data, mining, variable, heterogeneous, pattern, genetic has parent organization: University of Pennsylvania; Philadelphia; USA NCATS TR001263;
NEI EY022300;
NHLBI HL134015;
NIAID AI116794;
NIDDK DK112217;
NIEHS ES013508;
NLM LM009012;
NLM LM010098;
NLM LM011360;
Warren Center for Network and Data Science
PMID:30030120 Free, Available for download, Freely available https://epistasislab.github.io/ReBATE/ SCR_017139 Relief Based Algorithm Training Environment 2026-08-29 11:31:21 0
Unified Medical Language System
 
Resource Report
Resource Website
10+ mentions
Unified Medical Language System (RRID:SCR_006363) UMLS data access protocol, data or information resource, database, international standard specification, narrative resource, software resource, standard specification, web service Database of key terminology, classification and coding standards, and associated resources to promote creation of more effective and interoperable biomedical information systems and services, including electronic health records. This set of files and software brings together many health and biomedical vocabularies and standards to enable interoperability between computer systems. Users can use the UMLS to enhance or develop applications, such as electronic health records, classification tools, dictionaries and language translators. The UMLS has three tools, which we call the Knowledge Sources: * Metathesaurus: Terms and codes from many vocabularies, including CPT, ICD-10-CM, LOINC, MeSH, RxNorm, and SNOMED CT * Semantic Network: Broad categories (semantic types) and their relationships (semantic relations) * SPECIALIST Lexicon and Lexical Tools: Natural language processing tools We use the Semantic Network and Lexical Tools to produce the Metathesaurus. Metathesaurus production involves: * Processing the terms and codes using the Lexical Tools * Grouping synonymous terms into concepts * Categorizing concepts by semantic types from the Semantic Network * Incorporating relationships and attributes provided by vocabularies * Releasing the data in a common format Although we integrate these tools for Metathesaurus production, you can access them separately or in any combination according to your needs. The UMLS Terminology Services (UTS) provides three ways to access the UMLS: Web Browsers, Local Installation, and Web Services APIs. interoperability, electronic health record, classification tool, dictionary, language translator, classification, terminology, semantic, metathesaurus, vocabulary, thesaurus, natural language processing is used by: DisGeNET
is related to: MeSH
is related to: ConceptWiki
has parent organization: National Library of Medicine
NLM License required and only issued to individuals, Not to groups or organizations - no charge for licensing the UMLS from NLM. nlx_152104 SCR_006363 Unified Medical Language System (UMLS) 2026-08-29 11:27:50 47

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