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http://www.mayo.edu/research/centers-programs/translational-polycystic-kidney-disease-pkd-center/overview

Center that concentrates on the common, adult form of the disease, autosomal dominant PKD (ADPKD). The services provided focus on understanding the genetic basis of disease, more accurately monitoring disease progression and improving prognostics, and employing model systems to explore pathogenesis and conduct preclinical testing.

Proper citation: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester (RRID:SCR_015313) Copy   

•   Source: SciCrunch Registry

https://www.niddk.nih.gov/research-funding/research-programs/kidney-disease-centers

Research program whose aim is to make state-of-the art technologies and resources accessible to a broad spectrum of investigators pursuing studies in kidney research areas.

Proper citation: O'Brien Kidney Centers (RRID:SCR_015270) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/drtc

University-affiliated center that facilitates the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.

Proper citation: Vanderbilt Diabetes Research and Training Center (RRID:SCR_015153) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/

Imaging center which provides renal and urological researchers access to intravital optical microscopy and 3-dimensional quantitative digital image analysis.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis (RRID:SCR_015271) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/

Research center that maintains core facilities available for studies of cell biology, ion transport, and translational aspects of cystic fibrosis research.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center (RRID:SCR_015392) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/diabetes/

University-affiliated center to support both basic and clinical research in diabetes and related metabolic disorders with the ultimate purpose of translating findings into opportunities to prevent these diseases and to improve clinical care and outcomes.

Proper citation: University of Washington Diabetes Research Center (RRID:SCR_015126) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/cfrtc/

Research center that aims to provide resources and expertise to expedite development of potential new therapeutic approaches to correct dysfunctional CFTR and its secondary consequences, enhance understanding of evolving bacterial ecosystems and resultant host response in CF gastrointestinal and respiratory tracts, and how these interactions impact health. It also aims to develop improved assays, new drug screening assays, biomarkers and improved clinical outcome measures, as well as to better understand the metabolic and inflammatory consequences of CFTR dysfunction.

Proper citation: Cystic Fibrosis Center - University of Washington (RRID:SCR_015401) Copy   

•   Source: SciCrunch Registry

http://mmpc.med.umich.edu/

Research center which aims to contribute to a national database of metabolic phenotyping data in wild-type mouse strains and a broad range of mouse models relevant to the pathogenesis and treatment of diabetes, obesity and associated metabolic disorders. It also aims to foster continued technical development, refinement of assay sensitivity and specificity, data reproducibility, and transmission of best research practices within the areas of fundamental and applied diabetes and obesity research.

Proper citation: MMPC-University of Michigan Medical School (RRID:SCR_015373) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu

Community of scientists focused on the study of epithelial cell function and mucosal biology including inflammation and host defense of the gastrointestinal tract. It focuses on the intestinal and inflammatory bowel diseases; gut microbiology; and stem cell and developmental biology of the intestine and liver in organ physiology, regenerative medicine, and metabolism.

Proper citation: Harvard Digestive Disease Center (RRID:SCR_015587) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/idom/

NIDDK center that serves diabetes-oriented investigators from University of Pennsylvania as well as additional institutions from the mid-Atlantic region. The Penn DRC represents many basic science and clinical departments at Penn and the other institutions, and supports research in diabetes and obesity via Scientific Cores, a Pilot and Feasibility Grant Program, and a series of seminars, retreats, and other academic enrichment activities.

Proper citation: University of Pennsylvania Diabetes Research Center (RRID:SCR_015732) Copy   

•   Source: SciCrunch Registry

http://www.cidr.jhmi.edu/

Next generation sequencing and genotyping services provided to investigators working to discover genes that contribute to disease. On-site statistical geneticists provide insight into analysis issues as they relate to study design, data production and quality control. In addition, CIDR has a consulting agreement with the University of Washington Genetics Coordinating Center (GCC) to provide statistical and analytical support, most predominantly in the areas of GWAS data cleaning and methods development. Completed studies encompass over 175 phenotypes across 530 projects and 620,000 samples. The impact is evidenced by over 380 peer-reviewed papers published in 100 journals. Three pathways exist to access the CIDR genotyping facility: * NIH CIDR Program: The CIDR contract is funded by 14 NIH Institutes and provides genotyping and statistical genetic services to investigators approved for access through competitive peer review. An application is required for projects supported by the NIH CIDR Program. * The HTS Facility: The High Throughput Sequencing Facility, part of the Johns Hopkins Genetic Resources Core Facility, provides next generation sequencing services to internal JHU investigators and external scientists on a fee-for-service basis. * The JHU SNP Center: The SNP Center, part of the Johns Hopkins Genetic Resources Core Facility, provides genotyping to internal JHU investigators and external scientists on a fee-for-service basis. Data computation service is included to cover the statistical genetics services provided for investigators seeking to identify genes that contribute to human disease. Human Genotyping Services include SNP Genome Wide Association Studies, SNP Linkage Scans, Custom SNP Studies, Cancer Panel, MHC Panels, and Methylation Profiling. Mouse Genotyping Services include SNP Scans and Custom SNP Studies.

Proper citation: Center for Inherited Disease Research (RRID:SCR_007339) Copy   

•   Source: SciCrunch Registry

https://sdrc.stanford.edu/

University-affiliated center that promotes research in diabetes and related metabolic and endocrine disorders at Stanford University.

Proper citation: Stanford Diabetes Research Center (RRID:SCR_015856) Copy   

•   Source: SciCrunch Registry

https://hirnetwork.org/consortium/ctar

Consortium that is an independent research initiative of the Human Research Information Network (HIRN). It is investigating methods to increase or maintain functional beta cell mass in T1D through targeted manipulation of islet plasticity or engineered protection of beta cells from immune-mediated destruction.

Proper citation: HIRN Consortium on Targeting and Regeneration (RRID:SCR_016201) Copy   

•   Source: SciCrunch Registry

http://bioplex.hms.harvard.edu/

Database of cell lines with each expressing a tagged version of a protein from the ORFeome collection. The overarching project goal is to determine protein interactions for every member of the collection.

Proper citation: BioPlex (RRID:SCR_016144) Copy   

•   Source: SciCrunch Registry

https://hirnetwork.org/consortium/chib

Consortium that is an independent research initiative of the Human Research Information Network (HIRN). It is combining advances in beta cell biology and cell biology with tissue engineering technologies to develop microdevices that support functional human islets.

Proper citation: HIRN Consortium on Human Islet Biomimetics (RRID:SCR_016199) Copy   

•   Source: SciCrunch Registry

https://hirnetwork.org/consortium/cbds

Consortium that is an independent research initiative of the Human Research Information Network (HIRN). It is using human tissues to discover highly specific biomarkers of beta cell injury in asymptomatic T1D and developing strategies to stop beta cell destruction early in the disease process.

Proper citation: HIRN Consortium on Beta Cell Death and Survival (RRID:SCR_016198) Copy   

•   Source: SciCrunch Registry

https://hirnetwork.org/project/hirncc

Consortium that provides infrastructure to promote communication and collaboration among current and future HIRN participants, facilitating scientific advances and the sharing of data, tools, and reagents among HIRN members and the research community at large.

Proper citation: HIRN Coordinating Center (RRID:SCR_016395) Copy   

•   Source: SciCrunch Registry

http://toppgene.cchmc.org/

ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis.

Proper citation: ToppGene Suite (RRID:SCR_005726) Copy   

•   Source: SciCrunch Registry

http://www.cure.med.ucla.edu/

Center whose interests and activities encompass several facets of gastrointestinal regulatory physiology and cell biology. It provides an infrastructure to support basic, translational and clinical research and to facilitate interdisciplinary research and training activities in digestive diseases.

Proper citation: CURE - Digestive Diseases Research Center (RRID:SCR_004238) Copy   

•   Source: SciCrunch Registry

http://dkcoin.org/

THIS RESOURCE IS NO LONGER IN SERVICE, documented October 13, 2014. The resource has moved to the NIDDKInformation Network (dkNET) project. Contact them at info_at_dknet.org with any questions. Database of large pools of data relevant to the mission of NIDDKwith the goal of developing a community-based network for integration across disciplines to include the larger DKuniverse of diseases, investigators, and potential users. The focus is on greater use of this data with the objective of adding value by breaking down barriers between sites to facilitate linking of different datasets. To date (2013/06/10), a total of 1,195 resources have been associated with one or more genes. Of 11,580 total genes associated with resources, the ten most represented are associated with 359 distinct resources. The main method by which they currently interconnect resources between the providers is via EntrezGene identifiers. A total of 780 unique genes provide the connectivity between 3,159 resource pairs across consortia. To further increase interconnectivity, the groups have been further annotating their data with additional gene identifiers, publications, and ontology terms from selected Open Biological and Biomedical Ontologies (OBO).

Proper citation: dkCOIN (RRID:SCR_004438) Copy   

•   Source: SciCrunch Registry