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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.scienceexchange.com/facilities/mass-spectrometry-laboratory
The UTHSCSA Mass Spectrometry Laboratory provides state-of-the-art expertise and services in mass spectrometry and gel electrophoresis for identification, characterization and/or quantification of molecules of biomedical importance. The Mass Spectrometry Laboratory assists faculty members in their research endeavors and by promoting interdisciplinary and inter-institutional research. The activities of the Mass Spectrometry Laboratory continue to benefit the institution by enhancing ongoing research, by facilitating the acquisition of new research funding and by assisting with recruitment of new faculty members.
Proper citation: UTHSCSA Mass Spectrometry Laboratory (RRID:SCR_012240) Copy
Core is a fully automated, high-throughput genomic Center equipped with next generation sequencing and microarray platforms. TCGB provides genomics technologies, comprehensive services, specialized expertise and a wide range of trainings, enabling these services to serve basic science and translational/clinical research. In addition, TCGB provides pre-experiment consultation and post-experiment support, including preparation of grant applications, publications, and strategic planning for additional research steps. TCGB also provides educational training to faculty, staff, and students to raise awareness of new directions and major discoveries in the areas of genomics and bioinformatics.
Proper citation: University of California Los Angeles Technology Center for Genomics and Bioinformatics Core Facility (RRID:SCR_012204) Copy
http://www.scienceexchange.com/facilities/keck-biophysics-facility-northwestern
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 31,2025. The award-wining Keck Biophysics Facility at Northwestern University has a comprehensive set of state of the art instruments for biophysical and biochemical characterization of macromolecules and their interactions. We provide staff-service, technical expertise and assistance to investigators and companies in the continental US and Canada. The Facility has 15 years of experience with a broad array of biophysical techniques and has generated over 500 publications in top-tier journals.
Proper citation: Northwestern University Keck Biophysics Facility (RRID:SCR_012203) Copy
http://www.scienceexchange.com/facilities/affina-biotechnologies-inc
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Affina Biotechnologies is dedicated to excellence in helping our customers develop measurements of activities, kinetics and affinities of interactions and concentrations of biomolecules. We offer a unique mix of label-free and label-dependent assay technologies supported by scientific and technical expertise and a wide range of instrumentation.
Proper citation: Affina Biotechnologies (RRID:SCR_012207) Copy
http://www.scienceexchange.com/facilities/east-quad-nmr-facility-hms-harvard
Formerly the NERCE NMR Resource. Nuclear magnetic resonance spectroscopy is a powerful tool for studying structural and conformational parameters of molecules. This tool is vital for the chemical analysis of both small molecules (like those discovered in small-molecule screens) and large molecules, such as carbohydrates and proteins found to have potential biologic importance. This is a user-based NMR facility; users run their own experiments on the NMR spectrometer.
Proper citation: HMS East Quad NMR Facility (RRID:SCR_012295) Copy
http://nextgen.mgh.harvard.edu
Core facility that provides the following services: NextGen sequencing, Data Analysis. The NextGen Core is a collaboration between the Department of Molecular Biology, the Center for Human Genetics Research, the Center for Computational Biology, and the Executive Committee on Research (ECOR). Currently, the Core operates using a single Ilumina HiSeq instrument, accompanied by Illumina''''s cBot for cluster generation. This upgrade from our Genome Analyzer II doubled our capacity and greatly increased the data amount, quality, and stability over extra-long reads. The Core is located in the state-of-the-art Richard Simches Research Center on Cambridge St. as part of the MGH main campus in Boston. The many multi-investigator groups in the building - including those that study human genetics, stem cells, genomics, and more - make it the perfect location for the Core to service the researchers in those groups. The majority of customers come from MGH, but they also service customers at other academic medical centers and industry.
Proper citation: MGH NextGen Sequencing Core (RRID:SCR_012294) Copy
http://www.scienceexchange.com/facilities/ips-core
The new iPSC Core generates custom-designed iPSCs from mouse and human cells, including disease-specific human iPSCs. iPSCs from other species are currently under development. The Core is currently using both lentiviral- and sendai viral vector systems to deliver reprogramming factors to cells. Both systems are efficient, with the latter system having the advantage to generate iPSCs with a non-DNA-integrating vector system.
Proper citation: CU Denver iPSC Core (RRID:SCR_012176) Copy
http://www.scienceexchange.com/facilities/university-of-colorado-denver
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility
Proper citation: University of Colorado Denver Labs and Facilities (RRID:SCR_012175) Copy
http://www.scienceexchange.com/facilities/transgenic-and-gene-targeting-core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Transgenic and Gene Targeting Core is a full-service facility designed to assist you in generating genetically engineered mouse models for biomedical research. Our services include gene targeting in embryonic stem cells, the generation of ES cell-derived knockout and knockin mice, transgenic mice (conventional and BAC transgenic mice) and the cryo-preservation of mouse lines. The latter service is of particular importance for investigators that have long-term projects with non-commercial mouse lines. Changes in the genetic make-up of your mouse lines that occur spontaneously over time (gene drift) and disease outbreaks can significantly affect the outcome of your research. It is therefore advisable to preserve your mouse lines, providing you with a backup of your valuable research tools. We currently offer both embryo cryopreservation as well as sperm cryopreservation for this purpose.
Proper citation: CU Denver Transgenic and Gene Targeting Core (RRID:SCR_012177) Copy
http://www.mmc.edu/research/centers/research-centers/metrc/core-facilities.html
Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.
Proper citation: Meharry Proteomics Core (RRID:SCR_012179) Copy
https://www.monash.edu/researchinfrastructure/micromon
Provides complete sequencing and data analysis service based around second generation Illumina Genome Analyzer (GAIIx) and Illumina MiSeq sequencing platform. They also offer Agilent Bioanalyzer RNA and DNA analysis, Covaris focussed acoustic shearing of nucleic acids and tissues, qPCR assay design, execution and analysis, oligonucleotide synthesis and capillary electrophoresis (CE/Sanger) sequencing. Offers expertise in advanced DNA and RNA technologies.
Proper citation: Monash University Micromon Core Facility (RRID:SCR_012170) Copy
http://www.scienceexchange.com/facilities/yale-pathology-tissue-services
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Mission- Developmental Histology The mission of the Developmental Histology unit is to provide 1. Timely high quality histology services to the Yale community 2. Access to tissue services from Yale Pathology archives 3. To maximize the value of the resources in the Yale Pathology Tissue Archive. 4. To provide Tissue Microarrays to assess multiple tissue samples Mission- Yale Pathology Tissue Services To provide the maximum amount and quality of human tissue for research at Yale University without impacting diagnostic quality, accuracy and safety in anatomic pathology.
Proper citation: Yale Pathology Tissue Services (RRID:SCR_012290) Copy
https://lsom.uthscsa.edu/dcsa/research/cores-facilities/optical-imaging/
Service resource which makes imaging technology available to investigators on UTHSCSA campus and neighboring scientific community. Core Optical Imaging Facility offers access to technology for imaging of living cells, tissues, and animals, consultation, education and assistance regarding theory and application of optical imaging techniques, technical advice on specimen preparation techniques and probe selection.
Proper citation: Texas University Health Science Center at San Antonio Long School of Medicine Department of Cell Systems and Anatomy Optical Imaging Core Facility (RRID:SCR_012171) Copy
http://www.scienceexchange.com/facilities/cardiovascular-physiology-core-facility
The Cardiovascular Physiology Core Facility provides University of Wisconsin (UW) and non-UW researchers with a central resource for creating and studying animal models of disease on a fee-for-service basis. While the central focus of the facility is cardiovascular research, the techniques employed are often useful to investigators in other fields. Currently, the facility is conducting studies into diabetes, bone growth, drug toxicology, and gene therapy in liver and skeletal muscle, as well as cardiovascular disease. One of the most popular services provided by the facility is evaluation of the cardiovascular phenotype of transgenic mice.
Proper citation: UW-Madison Cardiovascular Physiology Core Facility (RRID:SCR_012214) Copy
http://www.scienceexchange.com/facilities/afm-imaging-group-k-state
We specialize in atomic force microscopy (AFM). We offer: 1. Various AFM imaging assays in air, water, and biological buffers. 2. Single molecule force spectroscopy (FX-AFM and FC-AFM) on proteins and other biomolecules. 3. Hot-tip AFM surface modifications and imaging.
Proper citation: KSU AFM Imaging Group (RRID:SCR_012216) Copy
http://www.scienceexchange.com/facilities/proteomics-shared-resource-facility-brown
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Proteomics Shared Resource Facility's mission is to provide well-maintained, state-of-the-art instrumentation and fundamental proteomics expertise to the Brown University and Rhode Island-EPSCoR scientific communities. It aims to be a focal point of intellectual activity in proteomics by enabling nationally recognized proteomics research within Rhode Island. As an NSF EPSCoR funded laboratory, the Proteomics Facility has a broadly-inclusive philosophy to ensure rapid and equal access to the facility's services for the entire Rhode Island research community. In addition to the acquisition of instrumentation, the Proteomics Core Facility will undertake the training of research in emerging proteomic techniques, a component that is essential to maintaining a productive and professional level of service. The Proteomics Facility has a strong commitment to be at the leading edge of current and developing technologies and provides consultation on their application.
Proper citation: Brown Proteomics Shared Resource Facility (RRID:SCR_012219) Copy
http://www.scienceexchange.com/facilities/high-throughput-and-high-content-screening-core-facility
The High Throughput and High Content Screening (HTS/HCS) Core Facility specializes in chemical biology as it relates to drug discovery, biological probe discovery, and phenotypic characterization of small-molecule effects on cellular systems. In addition to housing the instrumentation and robotics required for traditional HTS, the Core houses a cutting-edge High Content image-based system for next-generation small-molecule discovery research and analysis in fixed or live cells and cellular systems.
Proper citation: CU Denver High Throughput and High Content Screening Core Facility (RRID:SCR_012218) Copy
http://www.scienceexchange.com/facilities/dna-analysis-facility-yale
We are an academic Core Facility that supports the applications of DNA Sequencing and Fragment Analysis of Microsatellites and AFLP''''s. Our Facility was founded in 2003 and expanded in 2005 with funds from NSF Instrumentation Development Grant (#0500993). In 2008 a generous gift from the Yale Provost allowed us to upgrade our Applied Biosystems Genetic Analyzer from a 48 to a 96-capillary. In 2010, with funds from NIH Equipment Grant (1S10RR025478-01) we upgraded additional equipment to ensure that we are a an efficient throughput Core. We are housed in the Yale Institute for Biospheric Studies Molecular Systematics and Conservation Genetics Center both under the Direction of Dr. Adalgisa Caccone. The presence of our Core within this setting enhances training within the MSCG Center by allowing students to obtain genetic information from large data sets in a time frame that is appropriate to their academic schedules, and to do so within the budget available for training. Our services are utilized by over 600 users from Yale, other academic institutions and private companies from across the United States and around the world. By promoting access to our equipment we enhance cost effectiveness, reducing idle time and avoid wasting consumables. This in turn allows us to reduce rates and have our services available to users that could otherwise not afford it. While our user base continues to expand our focus remains the same: to offer high quality services at prices affordable to small and medium sized laboratories.
Proper citation: Yale DNA Analysis Facility (RRID:SCR_012187) Copy
http://www.scienceexchange.com/facilities/integrated-technology-enterprise-inc
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. We will design and produce DNA constructs for any purpose: Mutations/Deletions Knockout/Transgenic constructs Epitope tags & Fusion proteins Protein expression constructs Viral gene delivery constructs RNAi & related constructs Cost is generally about $300 per construct Turnaround time usually 5 business days
Proper citation: Integrated Technology Enterprise Inc (RRID:SCR_012186) Copy
http://www.scienceexchange.com/facilities/electron-microscopy-and-histology-core-facility-cornell
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. The EM & H Core Facility functions as a merger of the facility at WCMC and the Analytical Microscopy Facility at HSS. The microscopes are located at WCMC in the Department of Cell & Developmental Biology. The HSS facility staff performs the TEM specimen preparation for their clients and then comes to WCMC to use the TEM. SEM sample preps for both client groups may be performed in the facility at WCMC.
Proper citation: WCMC Electron Microscopy and Histology Core Facility (RRID:SCR_012222) Copy
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