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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://upr.eagle-i.net/i/0000012c-2bf2-d33a-5b95-f21080000000
Core facility that provides the following services: RNA extraction, Immunofluoresence assay, Dendritic cell immunophenotyping, ELISA, Polymerase chain reaction service, Florescence activated cell sorting service, Western blot analysis service. Research interests include: immunogenicity and protective efficacy of multi-clade consensus ENV SHIV virus-like particle vaccine, cellular innate activation as a tactic to prevent HIV-1 transmission, molecular changes after serial DV infections in macaques, and immunization of rhesus macaques with a dengue vaccine candidate based on a Venezuelan Equine Encephalitis (VEE) replicon vector.
Proper citation: UPR Virology Laboratory (RRID:SCR_010136) Copy
http://utep.eagle-i.net/i/00000134-aa21-2db4-bfc0-fe9780000000
Core facility that provides the following services: Confocal microscope access, Flow cytometry analyzer access, FACS Cell Sorting, Cell culture technique training, Cryopreservation of cultured cells, Cell culture analysis assistance, Preparation of high titer viral stock, Flow cytometry for cytotoxicity assay, Viral plaque assay, Real-time imaging of cell cultures, Mycoplasma testing, Treatment of cell lines contaminated with mycoplasma, Provide SF-9 cell suspension, Establishment of seed stocks, AnnexinV-FITC/PI assay. The Cell Culture and High Throughput Screening (HTS) Core Facility is a comprehensive research cell-culturing and cytometry facility established in 2007, as part of the Border Biomedical Research Center (BBRC). This facility was conceived to provide investigators, students and other researchers access to state-of-the-art technology for conducting experiments related to cellular, immune and physiological responses to stress, infectious agents, and toxicants. The laboratory also provides assistance and training related to cell culture techniques and equipment operation . The 1,756 sq ft core facility includes 6 individual cell culture suites that are available 24/7 to any researchers that have completed in-house training. The core also provides customized project support for experimental design and data analysis. The integration of the Cell Culture and HTS Core Laboratories has allowed investigators to screen a large number of compounds for their therapeutic potential against pathogens, cancer, and other diseases.
Proper citation: UTEP Cell Culture and High Throughput Screening Core Facility (RRID:SCR_010140) Copy
http://utep.eagle-i.net/i/00000134-aa23-3d2b-bfc0-fe9780000000
Core facility that provides the following services: DNA Sequencing Service, DNA/protein microarray printing. The DNA Analysis Core Facility supports researchers in their nucleic acid-based research studies on a 24/7 basis. The facility provides access to a wide range of genomic research tools including: DNA sequencing; microsatellite and fragment length polymorphism analysis; quantitative and real-time PCR; microarray analysis; and sophisticated nucleic acid analysis software. The DNA Analysis Core Facility services are available to external researchers from the RCMI program and other institutions for a nominal fee.
Proper citation: UTEP DNA Analysis Core Facility (RRID:SCR_010141) Copy
http://utep.eagle-i.net/i/00000134-aa24-006d-bfc0-fe9780000000
The long-term goal of the Statistical Consulting Laboratory (SCL) is to be a regional resource for the statistical support of basic science research, clinical or population based research, and evaluation of interventions designed to address issues of health and health disparities in the region''s population. As a major component of the Border Biomedical Research Center (BBRC), the Statistical Consulting Lab will continue to serve as a focal point from which all BBRC participants may obtain statistical and computing support for both their research and for the education of students in the graduate programs of the Biological Sciences Department. Statistical support is provided by a Ph.D. level staff statistician and five resource statisticians (counting the SCL core director) in the Department of Mathematical Sciences.
Proper citation: UTEP Statistical Consulting Laboratory (RRID:SCR_010142) Copy
http://utsa.eagle-i.net/i/00000135-783e-3187-d7c8-cf3780000000
The new Biophysics facility is committed towards providing computational biology tools and software designed to study the physical phenomena underlying the behavior of biological systems. Shortly, this facility will be furnished with a 6-quadcore server and 4 workstations with high resolution graphics capabilities and support for many simultaneous remote users. All these computing resources will be linked via 10GB optical wires. On the other hand, the Departmental network provides high speed access to the University Computer Center main-ports and Internet. As an extension of its functionality and performance, this facility will also share resources with the Computational Biology innovative at the Biology Department. A major goal is devoted to establishing the connection between this facility and the supercomputers at the Texas Advanced Computing Center (TACC) at 10GB data rate. This facility is currently used by the computational and theoretical biophysics researchers at the Department of Physics to study the properties of biomolecules that are strongly affected by their surrounding aqueous and ionic environment.
Proper citation: UTSA Biophysics Facility (RRID:SCR_010143) Copy
http://utsa.eagle-i.net/i/00000135-5d41-3cac-d7c8-cf3780000000
These laboratories are dedicated to ''Cellular and Tissue Engineering'' research activities which focus on in vitro studies of mammalian cell and protein interactions with material substrates, biomaterials (including nanostructured ones), biocompatibility, and the effect of select biochemical and biophysical (specifically, sustained and cyclic pressure and electrical) stimuli on mammalian cell function pertinent to new tissue formation and regeneration.
Proper citation: UTSA Cellular and Tissue Engineering Laboratory (RRID:SCR_010144) Copy
http://utsa.eagle-i.net/i/00000135-f9b6-93ba-3c2e-1e5380000000
The High Performance Computing Center/Computational Biology Initiative (HPC/CBI) is a new interdisciplinary initiative at the University of Texas Health Science Center at San Antonio (UTHSCSA) and the University of Texas at San Antonio (UTSA) which was launched in January 2005. The overall goal of the initiative is to build infrastructure to significantly advance collaborative interdisciplinary bioscience research in San Antonio.
Proper citation: UTSA Computational Biology Initiative (RRID:SCR_010145) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-2ff7-d10c-dacb-da6080000000
The objectives of the physiology core are to establish average values and normal ranges for physiologic parameters of renal function in mice, and to develop novel assays of mouse kidney structure and function. Our goal is to provide valuable institutional and national shared resources to facilitate better understanding of kidney diseases and treatments.
Proper citation: Vanderbilt Mouse Kidney Physiology Core Lab (RRID:SCR_010193) Copy
https://www.wistar.org/resources/flow-cytometry-facility/
Core facility that provides the following services: Immunophenotyping, Fluorescent protein expression analysis, Cell-cycle analysis, Functional assay service, Non-infectious cell sorting, BSL2+ biohazardous cell sorting, Flow cytometry consultation service, Flow cytometry training and ongoing advice, Flow cytometry data management service, Flow cytometry collaboration facilitation, Flow cytometer access. The Wistar Institute Flow Cytometry Shared Resource provides flow cytometric services, training, advice, and support for the use of flow cytometric techniques by Wistar Cancer Center investigators, as well as the greater basic research community.
Proper citation: Wistar Flow Cytometry Core Facility (RRID:SCR_010195) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-1120-feb3-dacb-da6080000000
The Rat Neurobehavioral Core provides equipment, training and consulting for Vanderbilt personnel who are interested in studying rat models of both neurological and psychiatric disorders. Examples of assays available for research in rats include models of anxiety, depression, drug abuse, learning and memory, cognition, attention, social interaction, pain, motor activity and coordination. Investigators can employ the latest technology in video capture and software-based analysis of behavior. Additionally, the facility offers a 24 hr/day home cage monitoring system that includes measurement of sleep EEG and core body temperature. A surgical suite is available, outfitted with a wide variety of equipment such as standard rat stereotaxic frames and a stereo-microscope, as well as various perfusion tables. Housing takes place inside the facility?s vivarium, which is Virus-Antibody free.
Proper citation: Vanderbilt Rat Neurobehavioral Laboratory (RRID:SCR_010196) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-a23d-093e-b4bd-8a1180000000
The Tissue Core laboratory provides direct proteome profiling and protein imaging of intact tissues by MALDI-MS. The Core also provides proteome profiling of biofluids by MALDI-MS as they pertain to a specific disease.
Proper citation: Vanderbilt Tissue Core Laboratory (RRID:SCR_010199) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-10e8-f177-dacb-da6080000000
Core facility that provides the following services: Simple Protein Identification, Multidimensional Protein Identification Technology, 2D Difference Gel Electrophoresis (2D-DIGE). The Proteomics Laboratory provides state-of the-art MS instrumentation and analytical methods to analyze proteins and proteomes.
Proper citation: Vanderbilt Mass Spectrometry Research Center Proteomics Laboratory (RRID:SCR_010190) Copy
https://labnodes.vanderbilt.edu/community/profile/id/1133
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides training and expertise in nutrition/diet methodology to obtain valid and reliable assessment and analyses of dietary intakes, nutritional status, body composition and metabolism.
Proper citation: Vanderbilt Diabetes Research and Training Center Vanderbilt Diet Body Composition and Metabolism Core Facility (RRID:SCR_010191) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-2ffc-7399-dacb-da6080000000
The overall goal of the Histology and Morphometry Core is 1) to provide a common facility and expertise for the broad spectrum of morphologic studies that may be required for interpretation of studies of various models of kidney disease and their response to interventions; 2) to provide tissue samples from existing archival specimens from various mouse and rat kidney disease models that may be used for exploration and characterization of expression patterns of various novel target molecules; and 3) to develop and enhance existing morphologic techniques to improve the ability of center investigators to localize specific molecules and tissue sections, and to interpret their significance based on the spatial localization and relationship to patterns of injury.
Proper citation: Vanderbilt Mouse Kidney Histology and Morphometry Core (RRID:SCR_010192) Copy
http://hawaii.eagle-i.net/i/0000012b-3599-5885-2f73-b43980000000
Core facility that provides the following services: Construction and validation of random-sheared DNA fragment libraries, DNA sequencing (Sanger) service, 96-well plasmid preparation service, Genotyping/fragment analysis, BAC end sequencing, Plasmid library construction service, Genome sequencing project. The ASGPB genome infrastructure currently consists of several state-of-the-art capillary-based DNA sequencers and accessory equipment to deal with large sample volumes. The facility can process up to 9000 samples per day with a projected sequence output of 6.75 Million bases. Several prokaryotic and one eukaryotic genome project are currently in progress. The facility offers DNA sequencing services for a wide range of templates including plasmid DNA, PCR fragments, cosmid DNA, and Bacterial Artificial Chromosomes (BACs). Sequencing reactions are performed using Applied Biosystems BigDye terminator chemistry and are run on ABI 3730XL capillary-based DNA sequencers.
Proper citation: UH Manoa Sequencing Facility (RRID:SCR_010114) Copy
http://upr.eagle-i.net/i/0000012b-00bf-6765-9e37-5ded80000000
Core facility that provides the following services: Sequencing service, Genotyping service. We are a low cost, fee-for-service facility designed to provide students and researchers in Puerto Rico with access to state-of-the-art equipment for collecting sequence and genotype data. We offer full service sequencing (reaction set-up, clean up, run and delivery) and fragment analysis data generation and offer personalized support to our users.
Proper citation: UPR AABRE Program: Sequencing and Genotyping Facility (RRID:SCR_010118) Copy
http://upr.eagle-i.net/i/0000012a-f732-79cc-6bbe-6fcf80000000
THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core aims to enhance biomedical research in Puerto Rico by providing resources for research, education and training. These resources will work to advance these specific aims: 1. enhance biomedical research in PR by providing researchers with the bioinformatics tools and technical support they require to perform cutting-edge biomedical research; 2. enhance the computational biology research environment in Puerto Rico by establishing research collaborations with biomedical, computational and mathematics researchers; 3. enhance multidisciplinary research by developing new courses and educational materials in computational biology, statistics and bioinformatics in collaboration with research faculty and the Science and Technology Competency Enhancement (STCE) Core; 4. enhance research by promoting advanced networking between PRAABRE member institutions, to enable collaborative research on and off the island; 5. enhance biomedical research by promoting effective access to scientific literature and databases for the biomedical researchers in PRAABRE; and 6. enhance biomedical research by enabling effective management of bibliographic information by fostering the use of bibliographic software and applying it to literature searches, articles and references management and manuscript writing.
Proper citation: University of Puerto Rico Biomedical Informatics Research Core (RRID:SCR_010119) Copy
http://upr.eagle-i.net/i/0000012d-1479-c6f4-bc92-16e380000000
Cayo Santiago is one of the world''s most renowned field sites for short term and longitudinal non-human primate studies. Its unique research value consists of:a stable and minimally disrupted long-term population management policy which allows investigators to plan and conduct longitudinal studies, an extensive and detailed computerized demographic database on the colony that provides information on individuals dating back to 1957, and DNA fingerprinting which is applied to confirm maternal and paternal relatedness of individuals.
Proper citation: UPR Cayo Santiago Caribbean Primate Research Center (RRID:SCR_010120) Copy
http://upr.eagle-i.net/i/0000012a-250a-2ace-43fb-601a80000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Oligonucleotide synthesis service, Automated DNA sequencing, Genotyping analysis service, Analysis of DNA, RNA or proteins, Microarray service. The long-term goal of the Center for Genomics in Health Disparities and Rare Diseases (CGHDRD) is to provide the critical environment that will enable high quality translational and biomedical research in pharmacogenomics, human genetics and genomics, molecular biology. We aim to develop and strengthen a collaborative research environment by providing research infrastructure that supports the focal areas of research at the University of Puerto Rico Medical Sciences Campus (UPR-MSC), which encompass common diseases such as cancer, neurological and cardiovascular disorders as well as rare disorders, by improving the human and physical resources. The Center focuses these initiatives on externally funded, interdisciplinary, collaborative projects which enhance the quality of translational, biomedical and clinical research at the Medical Sciences Campus linked to health disparities and rare disorders in Puerto Rico and nationally. Collaborations with researchers at institutions outside of Puerto Rico or other RCMI institutions, as well as other academic units in the island and in the UPR system are encouraged. The Center provides the necessary expertise to apply high throughput genotyping, expression profiling and sequencing technologies at the UPR-MSC. Specialized technical staff trains researchers at different levels of their scientific careers in supported technologies. Novel DNA and RNA isolation methodologies are applied to a diverse group of organisms and biological samples for nucleic acids sequence analysis in general.
Proper citation: UPR Center for Genomics in Health Disparities and Rare Disorders (RRID:SCR_010122) Copy
http://www.med.upenn.edu/genetics/dnaseq/index.shtml
Core facility that provides the following services: Large sequencing project support, Sanger sequencing service, High throughput DNA sequencing, Ion Torrent Personal Genome Machine sequencing, Template preparation and purification, Roche 454 sequencing, Sequence analysis and database search support, Construction of targeting vector for gene targeting, Genotyping and Fragment Analysis service, Molecular biology services, Mouse genotyping, and Ion Personal Genome Machine sequencing data analysis. The DNA Sequencing Facility provides long read, automated Sanger sequencing; microsatellite-based genotyping and fragment analysis; plasmid and BAC DNA preparation and purification; and related molecular biological services including PCR, cloning, sub-cloning, site-directed mutagenesis, and preparation of targeting vectors for gene targeting in mice. Core also provides services and support for analysis and interpretation of sequence data as well as the design of approaches to complex sequencing projects. For the last four years the facility has been providing Roche 454 sequencing service that includes library preparation, emulsion PCR and pyrosequencing for both genomic DNA and amplicons.
Proper citation: University of Pennsylvania Genomics Analysis Core (RRID:SCR_011061) Copy
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