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http://hawaii.eagle-i.net/i/0000012b-1c5f-99ef-06c2-9c7f80000000

Core facility that provides the following services: Training and advice for general imaging techniques, Histology processing service, Hematoxylin and eosin staining service, Training and advice for general histology techniques. This lab provides routine histology processing, specialized histochemical and immunohistological techniques, and access to several microscopic platforms. The core also provides technical assistance, training, and consultation in histological and imaging techniques to investigators throughout the University on a cost-recovery basis.

Proper citation: UH Manoa RCMI Histology and Imaging Core Facility (RRID:SCR_010109) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-c5d0-1c3d-a53f-a15a80000000

Core facility that provides the following services: Protein separation service, 2D gel production, Analysis of protein distribution of 2D gel, Standardized imaging of 2D gel, Mass spectrometry analysis service, Desalting, Trypsin Digestion. The mission of the UCC Biomedical Proteomic Facility is to accelerate discovery by giving UCC investigators access to cutting edge mass spectrometry are rapidly advancing and requires considerable technical expertise and expensive equipments. To keep UCC scientists competitive, new technologies will be incorporated into the facility as soon as possible to meet the needs. The facility is open to all investigators on collaboration or a fee-for-service basis. User fees will be adjusted depending on demand and to keep costs competitive.

Proper citation: UCC Biomedical Proteomic Facility (RRID:SCR_010073) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-aaee-9c0e-a272-8ee780000000

Core facility that provides the following services: HIV and HCV viral load extraction, Amplification and detection of HCV and HIV viral load, HIV-1 and HCV drug resistance genotyping, Neurotoxicity and neuroprotection assays, PBMC antiviral assay, MAGI antiviral assay, HIV-1 Tat inhibition assay, HIV p24 measurement service, Cytokine/Chemokine measurement, Hormone measurement, NF-kB expression induction assay, Detection of TH1, TH2, Treg, and TH17 cytokine profiles in T lymphocytes subsets, Immunophenotyping, intracellular cytokines/chemokines and apoptosis assay service, B and T cell immune activation, function, proliferation and differentiation assays, Macrophage function assay, Cell viability, cell proliferation and cytotoxicity, Cell cycle analysis, Inflammation and oxidative stress Calcium mobilization, kinase activation, and signal transduction, Gene expression service, Apoptosis test, In vivo/in vitro cytotoxicity measurement, Plaque and colony formation counting, Inflammation antibody array service, Apoptosis antibody array service, Angiogenesis antibody array, Protein and gene expression study, Standardized imaging of 2D gel. The laboratory supports research in the areas of HIV/AIDS and substances of abuse. Specialized facilities are made available to researchers for scientific studies in fields of immunology, drugs of abuse, HIV/AIDS and related infectious diseases. The core lab provides researchers with assays for nucleic acids detection, virus genotyping, flow cytometric phenotyping, lymphocyte proliferation, cytotoxic and non-cytotoxic activity, cytokine and chemokine determinations, and drugs of abuse quantification.

Proper citation: UCC HIV and Substance of Abuse Laboratory Core (RRID:SCR_010076) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-cb34-a797-a53f-a15a80000000

Core facility that provides the following services: Immunocytochemistry service. The immunocytochemistry laboratory specializes in the qualitative identification and localization of cells bearing selective markers by employing specific antibodies to these molecules.

Proper citation: UCC Immunocytochemistry Laboratory (RRID:SCR_010077) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-ca9b-b63c-a53f-a15a80000000

Core facility that provides the following services: Qualitative measure of neuronal death, Computerized image analysis. The goal of the facility is to assist UCC investigators in the use of cultured neurons, glias and organotypic cultures. The cultures are used for patch clamping after in vitro treatments with drugs of addiction or inhibitors and for in vitro models of neurodegenerative diseases. The core facility consists of a coordinator and a technician. Neuronal cultures are prepared from fetal cortex, hippocampus or astrocytes from cerebral cortex.

Proper citation: UCC Neuronal Glia Culture Facility (RRID:SCR_010078) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-2c98-3564-5b95-f21080000000

Core facility that provides the following services: Necropsy and tissue collection, Blood chemistries service, Bronchoalveolar lavage service, Cerebro-spinal tap service. The Animal Resources Center (ARC) is a part of the Unit of Comparative Medicine at the Medical Sciences Campus (MSC) of the University of Puerto Rico (UPR), committed to offer quality services to the university community and private entities, which through an accredited and properly regulated facility, and highly qualified personnel, provides care and maintenance of animals to be used in research.

Proper citation: UPR Animal Resources Center (RRID:SCR_010111) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-d046-71cb-a53f-a15a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. The facility offers microscope-based systems that allow the assessment of cellular responses, such as calcium signaling with fast temporal resolution. The facility offers 1) Confocal imaging services; 2) Brightfield, darkfield, phase contrast, Nomarski and epi-fluorescence imaging; 3) High spatial and temporal resolution imaging, 4) Collection of serial sections (Deconvolution capabilities) and 5) Morphometric analysis.

Proper citation: UCC Optical Imaging Facility (RRID:SCR_010079) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-469c-06c2-9c7f80000000

Core facility that provides the following services: Scanning electron microscopy service, Conventional and energy-filtering transmission electron microscopy service, Laser scanning confocal microscopy service, Fluorescence microscopy service, Laser microdissection and laser tweezing service. The Biological Electron Microscope Facility (BEMF) at the University of Hawai''i is a multi-user/service facility, administered by the Pacific Biosciences Research Center (PBRC). The mission of the BEMF is to provide biological-biomedical researchers with state-of-the-art instrumentation, training and services for high-resolution scanning electron microscopy, conventional and energy-filtering transmission electron microscopy, optical, fluorescence, and laser scanning confocal microscopy, and image analysis on a recharge basis. The facility receives partial support from the Pacific Biosciences Research Center and the UH Manoa Chancellor''s Office. Includes the Richard Allen Image Collection, a unique set of images taken with electron microscopes (http://www5.pbrc.hawaii.edu/allen/).

Proper citation: UH Manoa Biological Electron Microscope Facility (RRID:SCR_010087) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-b257-d364-2f73-b43980000000

The Biostatistics Shared Resource (BSR) provides statistical consultation and support to the research enterprise of the University of Hawai?i Cancer Center. The primary goal of the resource is to improve the quality of the research through sound statistical principles. The resource was established in 1995 and provides access to statistical support to all Center members on all aspects of research. The BSR provides short-term as well as long-term support for research projects. Support is provided to scientists in epidemiology, health behavior and quality of life research, and molecular and clinical oncology. The members of the Shared Resource often serve as co-investigators on epidemiology and cancer prevention and control projects. Consultation is available in the following areas: design, data collection, data analysis, statistical programming, interpretation and dissemination of results, and protocol review. The members of the resource have contributed to the publication of many peer-reviewed manuscripts from Center research projects. In addition, the statisticians work on methodological issues important to the research ongoing at UH Cancer Center. One area of interest is measurement error models that correct for bias in model parameter estimates when the exposure variable is measured with error. The role of dietary intake and sunlight exposure in cancer etiology are of interest at the Center, and these variables are measured with error. Another interest is in how susceptibility genes affect cancer risk, in combination with exposure data. Therefore, statistical techniques for the investigation of genes and lifestyle-gene interactions in cancer models are also studied.

Proper citation: UH Manoa Biostatistics Shared Resources (RRID:SCR_010088) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-0387-c99c-aef680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides access to high speed computer hardware and bioinformatics consultation. Research at the facility includes studying of evolutionary change in emergent dengue viruses associated with increasingly severe epidemics and confirm the impact of these changes in experimental models.

Proper citation: University of Hawaii at Manoa Centers of Biomedical Research Excellence Bioinformatics Core Facility (RRID:SCR_010089) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-e488-f75c-a272-8ee780000000

Core facility that provides the following services: Nucleic acid sequencing service, Real-Time PCR services, Cell culture service, Protein quantitation assay, Nucleic acid estimation service, Fusion protein purification and expression service, Transfection service, Site-directed mutagenesis service, Primer design service, Gel electrophoresis service, Polymerase chain reaction service. The Protein and Nucleic Acid Core Facility (PNACF) aids in the transition from classical to molecular analysis of the problems being addressed by faculty members. PNACF focuses on faculty training, seminars, training on specialized molecular biology techniques, protein expression and protein purification and characterization.

Proper citation: UCC Protein and Nucleic Acid Core Facility (RRID:SCR_010080) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-36a1-152c-2f73-b43980000000

Core facility that provides the following services: Solid state studies service.

Proper citation: UH Manoa NMR Lab (RRID:SCR_010082) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000134-ed9a-ccf6-77e4-a45080000000

The Major Instrumentation Core has been established to provide technical services and consumable supplies necessary for the operation and maintenance of a variety of major instruments that support biomedical research at Xavier University. The long term goal of the Major Instrumentation Core is to enhance the overall biomedical research capabilities at Xavier University by making available essential instrument-based platforms for various research projects. To achieve this goal the Major Instrumentation Core has set the following specific aims: 1). support biomedical research projects on campus by providing essential analytical instrumentation, 2). maintain and operate existing instruments, 3). acquire new instruments, and 4). provide technical support for user community of the core.

Proper citation: XULA Major Instrumentation Core (RRID:SCR_010209) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a1a9-3071-b4bd-8a1180000000

Core facility that provides the following services: Hematology Services, Parasitology Services, Chemistry Analysis Services, Cell Line Testing, Customizable Chemistry Analysis, Phenotyping Services, Infertility evaluation in male mice, Veterinary Pathologist Consultation. Access to consented and de-identified human tissue specimens; Comprehensive, state of the art diagnostic, necropsy and comparative pathology services for animal model systems with specific expertise and focus on mouse models; Research histology including advanced techniques, immunohistochemistry, immunofluorescence, laser capture micro-dissection and tissue micro-array preparation; Access to experts in veterinary and human pathology.

Proper citation: Vanderbilt Translational Pathology Shared Resource (RRID:SCR_010201) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-362c-e975-dacb-da6080000000

The Chemical Synthesis Core was established within the Vanderbilt Institute of Chemical Biology with the goal of supporting the organic and medicinal chemistry needs of investigators. The primary focus of the core is to facilitate biology-orientated projects within the medical center and the university by assisting with the chemistry aspect of the project. The core works independently or in collaboration with the VICB High Throughput Screening Center on the synthesis of literature-cited compounds (including patented ones) as well as full scale lead optimization of a compound.

Proper citation: Vanderbilt Chemical Synthesis Core Laboratory (RRID:SCR_010169) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-1107-96fa-dacb-da6080000000

The current zebrafish facility is composed of approximately 100 research tanks available for short and long-term studies, and a significant expansion project is underway. The facility enables investigator access to the unique advantages of the zebrafish model, which provides hundreds of mutant and transgenic zebrafish with unique properties suited for specific experiments. This core?s essential mission is to provide a reliable mechanism for incorporation and propagation of new and existing zebrafish lines into the core.

Proper citation: Vanderbilt Zebrafish Aquatic Facility (RRID:SCR_010202) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/genomics-facility/

Core facility that provides the following services: Microarray services, RNA amplification service, ABI 7900 Real-time qPCR service, Capillary DNA sequencing and microsatellite analysis, Illumina HiSeq 2000 sequencing service, Illumina Genome Analyzer services. The Wistar Genomics Facility serves as a hub for consultation and scientific interactions relating to nucleic-acid based methods and provides expertise and support to insure the best possible use of emerging nucleic-acid technologies. In addition to consultation and collaboration with Wistar Cancer Center members, the Facility provides services to the greater scientific community. The establishment of this facility was supported in part by an NCI Cancer Center Support Grant and equipment grants from the Commonwealth of Pennsylvania, The Pew Charitable Trusts and the National Cancer Institute.

Proper citation: Wistar Genomics Core Facility (RRID:SCR_010205) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/biomedical-research-support-facility/histotechnology/

Core facility that provides the following services: Paraffin sectioning service, Frozen sectioning service, Histology staining services. This facility provides basic histology services. These include fixing, processing and paraffin embedding of all types of tissues for light microscopy (i.e. routine stains, immunohistochemistry or in situ hybridization). Routine hematoxylin and eosin staining as well as special staining is done in the lab. Slides are prepared for immunohistochemistry and in situ and immunohistochemistry. Frozen sectioning is also available. It is advisable to contact the facility about freezing techniques so the best sections can be obtained.

Proper citation: Wistar Histotechnology Core Facility (RRID:SCR_010206) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/imaging-facility/

Core facility that provides the following services: Live-cell time-lapse microscopy, Low magnification and photomacrography? service, Confocal microscopy service, Two-photon microscopy, Small animal whole body luminescence and fluorescence imaging?, 2, 3, 4, and 5D image analysis, Imaging consultation service, Imaging equipment, image processing, and image analysis training, In-lab microscopy assistance and maintenance service, Imaging Facility instrument access. The Imaging Facility is a shared resource with the primary goal of providing exceptional microscopy and imaging services, as well as individual access to a variety of state-of-the-art imaging resources for members of the Wistar research community. The imaging systems have been designed to be extremely flexible to reflect a broad range of challenging scientific questions and specimens. Each system provides a combination of illumination, optics and image capture options. Diverse subjects ranging from fluorescently tagged live cell cultures and stained tissue sections, to 3D tumor spheroids and low magnification explanted tissues, can be accommodated with available systems. Current equipment includes standard upright and inverted fluorescence microscopes, a customized live-cell time lapse microscope capable of 6D imaging, a laser scanning confocal microscope, a 2-photon microscope designed for in vivo imaging, a small animal, whole body luminescence and fluorescence imager, special low magnification (photomacrography) systems as well as a variety of traditional photographic cameras, lenses and lighting equipment. Users of the facility may be trained for unassisted use of all core assets, or they may elect assisted service with the facility staff performing the imaging. The Imaging staff also provides assistance to researchers with additional aspects of their imaging requirements. Ideal approaches to specimen documentation are often unique to the experiment and the staff can help design the most effective imaging protocols to answer a particular question. On-site assistance is available to help investigators get the most out of their own systems. Image analysis and specialized Photoshop training, creative imaging for journal covers, and guidance on digital imaging ethics help to round out the services available from the facility.

Proper citation: Wistar Imaging Core Facility (RRID:SCR_010207) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c643-b905-b341-4bb480000000

An Core facility

Proper citation: Vanderbilt Clinical Trials Center (RRID:SCR_010171) Copy   

•   Source: SciCrunch Registry