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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) data analysis software, data processing software, sequence analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka, https://sources.debian.org/src/prokka/, https://sources.debian.org/src/prokka/ SCR_014732 2026-09-19 12:53:01 4882
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) data analysis software, data processing software, sequence analysis software, software application, software resource Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-09-19 12:53:03 1
DOGMA
 
Resource Report
Resource Website
100+ mentions
DOGMA (RRID:SCR_015060) software resource, web application Web-based annotation tool for plant chloroplasts and animal mitochondrial genomes. DOGMA allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. chloroplast, mitochondria, genome annotation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
PMID:15180927 Freely available biotools:DOGMA https://bio.tools/DOGMA SCR_015060 Dual Organellar GenoMe Annotator, Dual Organellar GenoMe Annotator (DOGMA) 2026-09-19 12:53:05 428
Online Resource for Community Annotation of Eukaryotes
 
Resource Report
Resource Website
10+ mentions
Online Resource for Community Annotation of Eukaryotes (RRID:SCR_014989) OrcAE, ORCAE data or information resource, narrative resource, wiki Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community. genome annotation, gene validation, community driven, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Bioinformatics Gent
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:23132114 Free, Account required, The research community can contribute to this resource biotools:orcae https://bio.tools/orcae SCR_014989 Online Resource for Community Annotation of Eukaryotes (OrcAE) 2026-09-19 12:53:04 17
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) data analysis software, data processing software, data visualization software, sequence analysis software, software application, software resource Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview, https://sources.debian.org/src/seaview/ SCR_015059 2026-09-19 12:53:06 1817
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) data analysis software, data processing software, sequence analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX, https://bio.tools/MeroX, https://bio.tools/MeroX SCR_014956 2026-09-19 12:53:04 74
BUSCO
 
Resource Report
Resource Website
5000+ mentions
BUSCO (RRID:SCR_015008) algorithm resource, data analysis software, data processing software, software application, software resource Software tool to quantitatively measure genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. genome assembly, annotation completeness, quantitative method, bio.tools is used by: rnaQUAST
is recommended by: CEGMA
is listed by: Debian
is listed by: bio.tools
is related to: CEGMA
works with: BUSCOMP
Marie Curie International Outgoing Fellowship ;
Swiss National Science Foundation
DOI:10.1093/bioinformatics/btv351 Free, Available for download, Freely available biotools:busco https://gitlab.com/ezlab/busco, https://bio.tools/busco, https://sources.debian.org/src/busco/ SCR_015008 BUSCO v2, Benchmarking Universal Single-Copy Orthologs (BUSCO), Benchmarking Universal Single-Copy Orthologs, BUSCO v1 2026-09-19 12:53:05 8320
PARASAIL
 
Resource Report
Resource Website
1+ mentions
PARASAIL (RRID:SCR_021805) alignment software, data processing software, image analysis software, software application, software resource Software tool as multiple sequence alignement for global, local and semi global alignments. multiple sequence alignement, global alignments, local alignments, semi global alignments, is listed by: Debian Pacific Northwest National Laboratory DOI:10.1186/s12859-016-0930-z Free, Available for download, Freely available https://sources.debian.org/src/libparasail-dev/ SCR_021805 Pairwise Sequence Alignment Library 2026-09-19 12:54:58 4
ToppCluster
 
Resource Report
Resource Website
100+ mentions
ToppCluster (RRID:SCR_001503) ToppCluster analysis service resource, data analysis service, production service resource, resource, service resource A tool for performing multi-cluster gene functional enrichment analyses on large scale data (microarray experiments with many time-points, cell-types, tissue-types, etc.). It facilitates co-analysis of multiple gene lists and yields as output a rich functional map showing the shared and list-specific functional features. The output can be visualized in tabular, heatmap or network formats using built-in options as well as third-party software. It uses the hypergeometric test to obtain functional enrichment achieved via the gene list enrichment analysis option available in ToppGene. term enrichment, gene, analysis, gene enrichment analysis, connectivity, heatmap, ortholog, microarray, function, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GenitoUrinary Development Molecular Anatomy Project
is related to: ToppGene Suite
NIDDK 1U01DK70219;
NIDDK P30DK078392;
NCRR U54 RR025216;
NIDCR U01DE020049
PMID:20484371 Free OMICS_02225, nlx_152801, biotools:toppcluster https://bio.tools/toppcluster SCR_001503 ToppCluster: A multiple gene list feature analyzer for the dissection of biological systems 2026-09-19 12:55:04 152
StatAlign
 
Resource Report
Resource Website
1+ mentions
StatAlign (RRID:SCR_001892) data analysis software, data processing software, sequence analysis software, software application, software resource Software package for Bayesian analysis of protein, DNA and RNA sequences. It utilizes multiple alignments, phylogenetic trees and evolutionary parameters to quantify uncertainty in these analyses. It is written in Java. software package, bayesian, protein, dna, rna, sequencing, java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
PMID:23335014 Free, Available for download, Freely available biotools:StatAlign, OMICS_03743 https://bio.tools/StatAlign SCR_001892 StatAlign 2.0 2026-09-19 12:55:04 1
FACTA+.
 
Resource Report
Resource Website
1+ mentions
FACTA+. (RRID:SCR_001767) FACTA+ data access protocol, service resource, software resource, web service Text mining tool to discover associations between biomedical concepts from MEDLINE articles. Use the service from your browser or via a Web Service. The whole MEDLINE corpus containing more than 20 million articles is indexed with an efficient text search engine, and it allows you to navigate such associations and their textual evidence in a highly interactive manner - the system accepts arbitrary query terms and displays relevant concepts immediately. A broad range of important biomedical concepts are covered by the combination of a machine learning-based term recognizer and large-scale dictionaries for genes, proteins, diseases, and chemical compounds. There is also a FACTA+ visualization service that can be found here: http://www.nactem.ac.uk/facta-visualizer/ text mining, gene, protein, disease, symptom, drug, enzyme, compound, biomedical, association, machine learning, chemical, text-mining software, bio.tools is listed by: OMICtools
is listed by: FORCE11
is listed by: bio.tools
is listed by: Debian
is related to: MEDLINE
has parent organization: National Centre for Text Mining
JISC PMID:18772154 Free, Freely available biotools:facta_plus, nif-0000-10272, OMICS_01181 http://refine1-nactem.mc.man.ac.uk/facta/, https://bio.tools/facta_plus SCR_001767 Finding Associated Concepts with Text Analysis 2026-09-19 12:55:04 2
FusionCatcher
 
Resource Report
Resource Website
1+ mentions
FusionCatcher (RRID:SCR_000060) data analysis software, data processing software, sequence analysis software, software application, software resource Software that searches for novel/known fusion genes, translocations, and chimeras in RNA-seq data (paired-end reads from Illumina NGS platforms like Solexa and HiSeq) from diseased samples. fusion gene, known fusion gene, translocation, chimera, rna-seq data, hiseq, solexa, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1101/011650 Free, Available for download, Freely available biotools:fusioncatcher, OMICS_01348 https://github.com/ndaniel/fusioncatcher/blob/master/doc/manual.md, https://bio.tools/fusioncatcher http://code.google.com/p/fusioncatcher/ SCR_000060 2026-09-19 12:55:03 9
Dissect
 
Resource Report
Resource Website
Dissect (RRID:SCR_000058) Dissect alignment software, data processing software, image analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software transcriptome-to-genome alignment tool, which can identify and characterize transcriptomic events such as duplications, inversions, rearrangements and fusions. Structural events containing transcripts, transcriptome-to-genome alignment, identify and characterize transcriptomic events, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Simon Fraser University; British Columbia; Canada
PMID:22689759 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01346, biotools:dissect https://bio.tools/dissect SCR_000058 Dissect: DIScovery of Structural Events Containing Transcripts, DIScovery of Structural Events Containing Transcripts 2026-09-19 12:55:03 0
fgsea
 
Resource Report
Resource Website
100+ mentions
fgsea (RRID:SCR_020938) data analysis software, data processing software, software application, software resource Software R package for fast preranked gene set enrichment analysis. Allows to make more permutations and get more fine grained p-values, which allows to use accurate stantard approaches to multiple hypothesis correction. Gene set enrichment analysis, preranked gene set, multiple hypothesis correction, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
DOI:10.1101/060012 Free, Available for download, Freely available biotools:fgsea https://github.com/ctlab/fgsea/, https://bio.tools/fgsea SCR_020938 fast gene set enrichment analysis, Fast Gene Set Enrichment Analysis, FGSEA 2026-09-19 12:54:46 237
Bs-Seeker2
 
Resource Report
Resource Website
1+ mentions
Bs-Seeker2 (RRID:SCR_020948) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool as versatile aligning pipeline for bisulfite sequencing data. Used for mapping bisulfite sequencing data and generating DNA methylomes. Improves mappability over existing aligners by using local alignment. Maps reads from RRBS library by building special indexes with improved efficiency and accuracy. Provides additional function for filtering out reads with incomplete bisulfite conversion, which is useful in minimizing overestimation of DNA methylation levels. Versatile aligning pipeline, bisulfite sequencing data, mapping bisulfite sequencing data, generating DNA methylomes, DNA methylation level, reads mapping, Reduced Represented Bisulfite Sequencing library, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: BS Seeker
has parent organization: University of California at Los Angeles; California; USA
China Scholarship Council ;
Institute of Genomics and Proteomics at UCLA ;
NBRPC 2012CB316503
PMID:24206606 Free, Available for download, Freely available biotools:bs-seeker2 http://pellegrini.mcdb.ucla.edu/BS_Seeker2/, https://bio.tools/bs-seeker2 SCR_020948 Bisulfite Sequencing Seeker2, BS Seeker2 2026-09-19 12:54:46 2
GraBCas
 
Resource Report
Resource Website
GraBCas (RRID:SCR_000205) GraBCas software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software tool for predicting granzyme B and caspase cleavage sites. matlab, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:15980455 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01674, biotools:grabcas https://bio.tools/grabcas SCR_000205 2026-09-19 12:49:18 0
riboPicker
 
Resource Report
Resource Website
1+ mentions
riboPicker (RRID:SCR_000360) software resource Software to automatically identify and efficiently remove rRNA-like sequences from metatranscriptomic and metagenomic datasets. standalone software, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:22155869 Free, Available for download, Freely available OMICS_02618, biotools:ribopicker https://bio.tools/ribopicker SCR_000360 2026-09-19 12:49:21 2
ARACHNE
 
Resource Report
Resource Website
1+ mentions
ARACHNE (RRID:SCR_000351) ARACHNE software resource A software for genome assembly, and is specifically designed to analyze long Sanger-chemistry reads. genome, sequencing, analysis, sanger, chemistry, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Broad Institute
PMID:11779843 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01812, biotools:arachne https://bio.tools/arachne SCR_000351 ARACHNE: a whole-genome shotgun assembler, ARACHNE (Unsupported) 2026-09-19 12:49:21 3
PSCBS
 
Resource Report
Resource Website
PSCBS (RRID:SCR_000417) data analysis software, data processing software, sequence analysis software, software application, software resource Software R package for segmentation of allele-specific DNA copy number data and detection of regions with abnormal copy number within each parental chromosome. Both tumor-normal paired and tumor-only analyses are supported. abnormal copy number regions detection, allele specific DNA copy number data segmentation, is listed by: OMICtools
is listed by: Debian
is related to: CRAN
has parent organization: University of California at San Francisco; California; USA
PMID:21666266
DOI:10.1093/bioinformatics/btr329
Free, Available for download, Freely available OMICS_05545 https://sources.debian.org/src/r-cran-pscbs/ SCR_000417 PSCBS: Analysis of Parent-Specific DNA Copy Numbers 2026-09-19 12:49:23 0
NucleoFinder
 
Resource Report
Resource Website
1+ mentions
NucleoFinder (RRID:SCR_000368) NucleoFinder software resource A software for a statistical approach for the detection of nucleosome positions in a cell population. The software identifies important features of nucleosome organization such as the spacing downstream of active promoters and the enrichment and depletion of GC/AT dinucleotides of in vitro nucleosomes. nucleusome, position, promoter, analysis, downstream, nucleotide, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23297036 THIS RESOURCE IS NO LONGER IN SERVICE biotools:nucleofinder, OMICS_00510 https://omictools.com/nucleofinder-tool, https://bio.tools/nucleofinder SCR_000368 2026-09-19 12:49:21 1

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