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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.miltenyibiotec.com/US-en/products/myelin-removal-beads-ii-human-mouse-rat.html#2x4-ml
Developed for specific removal of myelin debris from single cell suspensions. Myelin Removal Beads II work without determination of cell number or myelin debris cell ratio.
Proper citation: Miltenyi Human, Mouse, Rat Myelin Removal Beads II Removal Reagent (RRID:SCR_020279) Copy
https://www.miltenyibiotec.com/US-en/products/whole-skin-dissociation-kit-human.html#130-101-540
Enables generation of single cell suspensions from human skin tissue without separating dermis and epidermis. Kit has been developed for isolation of fibroblasts from diverse human skin biopsies as well as for phenotyping or enumeration of human skin cell populations by flow cytometry.
Proper citation: Miltenyi Human Whole Skin Dissociation Kit (RRID:SCR_020277) Copy
https://www.bio-rad.com/en-us/product/t100-thermal-cycler?ID=LGTWGIE8Z
Small compact 96well thermal cycler. PCR system features intuitive touch screen and thermal gradient technology to optimize reaction in single run.
Proper citation: Bio-Rad: T100 Thermal Cycler (RRID:SCR_021921) Copy
https://www.visualsonics.com/product/imaging-systems/vevo-3100
Vevo 3100 micro ultrasound imaging system reduces speckle noise and artifacts while preserving and enhancing critical information for small animal in vivo studies. System helps you visualize your data at high resolution.
Proper citation: Fujifilm: Vevo 3100 Imaging System (RRID:SCR_022152) Copy
Designed to eliminate complexities of microscopy, EVOS XL Core system captures high-quality brightfield cell images right at your benchtop within minute. Instrument for monitoring cell cultures, either within hood or in cell culture room.
Proper citation: Thermo Fisher: EVOS XL Core Imaging System (RRID:SCR_022190) Copy
https://jwst.nasa.gov/content/observatory/instruments/nircam.html
Instrument aboard the James Webb Space Telescope. It has two major tasks, as imager from 0.6 to 5 micron wavelength, and as wavefront sensor to keep 18-section mirrors functioning as one. Imager covers infrared wavelength range 0.6 to 5 microns. NIRCam detects light from the earliest stars and galaxies in process of formation, population of stars in nearby galaxies, as well as young stars in Milky Way and Kuiper Belt objects. NIRCam is equipped with coronagraphs, instruments that allow astronomers to take pictures of very faint objects around central bright object, like stellar systems.
Proper citation: Near Infrared Camera (RRID:SCR_022113) Copy
https://mass-spec.stanford.edu/instruments
System includes Thermo Orbitrap Eclipse Tribid mass spectrometer and Waters M-Class Acquity nanoUPLC. This platform features sequential acquisition capabilities and multiple fragmentation types, enabling complex, in depth proteomic experiments.
Proper citation: Thermo Fisher: Orbitrap Eclipse nanoLC/MS system (RRID:SCR_022212) Copy
https://www.olympus-lifescience.com/data/olympusmicro/brochures/pdfs/ix71.pdf?rev=EABE
Research inverted system microscope. Olympus IX2 inverted microscope combined with UIS2 optical system. Used for live cell experiments.
Proper citation: Olympus: IX71 Microscope (RRID:SCR_022185) Copy
http://www.pstnet.com/software.cfm?ID=96
Designed for use in an MRI simulator, MoTrak software uses Ascension Technology?s Flock of Birds. The sensor attaches to the subject?s head and determines the position of the head in space relative to the transmitter. The sensor records angular rotations as well as positional displacements from an initially calibrated position. This information is displayed and logged by the program in real-time, allowing observation of head motion in an MRI simulator. In the simulator, the participant can simultaneously be habituated to the MRI environment, while being trained to remain still via feedback from the MoTrak system.
Proper citation: MoTrak Head Motion Tracking System (RRID:SCR_009607) Copy
http://jsu.eagle-i.net/i/0000012b-00bd-5152-3984-bcfb80000000
A research laboratory and facility which supports research on environmental toxicology at Jackson State University.
Proper citation: JSU Environmental Toxicology Core Lab (RRID:SCR_000884) Copy
http://edboyden.org/05.09.boyden.html
Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells.
Proper citation: Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) Copy
https://www.thermofisher.com/order/catalog/product/CHROMELEON7
Software system to support chromatography operations, to ensure data quality and manage all the analytical processes from instrument control, to raw data storage and processing, through to generating the final results.
Proper citation: Chromeleon Chromatography Data System (CDS) Software (RRID:SCR_016874) Copy
https://www.rankinbiomed.com/product/refurbished-american-optical-860-sliding-micrtome/
THIS REOURCE IS NO LONGER IN SERVICE. Documented on September 29,2023. Sliding microtome used for cutting hard objects such as bone, wood, frozen celloidin, and paraffin preparations. Cutting thickness is adjustable from 1 to 40 microns.
Proper citation: American Optical: 860 Sliding Microtome (RRID:SCR_018434) Copy
https://atagousa.corecommerce.com/PAL-10S-p358.html
Digital hand held pocket refractometer that measures urine specific gravity. It has measurement temperature of 10 to 35 C and sample volume of 0.3ml.
Proper citation: Atago: PAL-10S Pocket Refractometer (RRID:SCR_018439) Copy
https://www.sutter.com/manuals/P-2000_OpMan.pdf
Microprocessor controlled, CO2 laser based micropipette puller.Default configuration allows fabrication of micropipettes for intracellular recording, patch clamping, microinjection and microperfusion.Can store up to 100 separate programs, each consisting of up to 8 command lines. The five parameters set in each command line allow exquisite control of the micropipette taper geometry. Allows the use of wide range of glass diameters from 0.125 to 1.2 mm.
Proper citation: Sutter: P-2000 Laser Micropipette Puller (RRID:SCR_018640) Copy
https://github.com/PIEFoundry/Microfabrication/wiki/Parylene-MEA-Fabrication
Parylene MEA Fabrication is related to SPARC. Repository for standard fabrication procedure for Parylene C microelectrode arrays and similar devices.
Proper citation: HORNET CENTER FOR AUTONOMIC NERVE RECORDING AND STIMULATION SYSTEMS (RRID:SCR_023681) Copy
Benchtop genetic analyzer. Electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow.
Proper citation: Agilent: 4200 TapeStation System (RRID:SCR_018435) Copy
http://tools.thermofisher.com/content/sfs/manuals/cms_040970.pdf
Automated PCR instrument for automated amplification of nucleic acids with Polymerase Chain Reaction. It has reaction volumes of up to 50 uL and sample temperature range of 4 to 99.9 C.
Proper citation: Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System (RRID:SCR_018436) Copy
https://docplayer.net/37250096-Fei-philips-cm120-tem.html
Transmission electron microscope with maximum acceleration voltage of 120 kv.Microscope primarily used for sample screening.
Proper citation: Philips: FEI CM120 BioTwin Transmission Electron Microscope (RRID:SCR_024709) Copy
https://www.emerson.com/en-us/catalog/branson-sfx250
Branson Sonifier ultrasonic cell disruptor / homogenizers are versatile laboratory units suitable for broad range of liquid processing applications. Digital sonifier to disrupt cells, bacteria, spores, or tissue. Ideal for initiating and accelerating chemical, biochemical, and physical reactions, and for degassing liquids. Used to prepare emulsion to 0.01 micron, homogenize immiscible liquids, polymerize some materials, and depolymerize others.
Proper citation: Emerson: Branson Digital Sonifier SFX250 (RRID:SCR_024710) Copy
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