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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Experimental Conditions Ontology
 
Resource Report
Resource Website
1+ mentions
Experimental Conditions Ontology (RRID:SCR_003306) XCO controlled vocabulary, data or information resource, ontology An ontology designed to represent the conditions under which physiological and morphological measurements are made both in the clinic and in studies involving humans or model organisms. obo, clinical, physiology, morphology, measurement is listed by: BioPortal
is listed by: OBO
has parent organization: Medical College of Wisconsin; Wisconsin; USA
PMID:22654893 Free, Available for download, Freely available nlx_157401 ftp://rgd.mcw.edu/pub/ontology/experimental_condition/experimental_condition.obo, http://sourceforge.net/projects/phenoonto/ SCR_003306 Experimental condition ontology 2026-09-12 12:55:55 1
Sage Bionetworks
 
Resource Report
Resource Website
100+ mentions
Sage Bionetworks (RRID:SCR_003384) nonprofit organization Non-profit biomedical research organization developing predictors of disease and accelerating health research through creation of open systems, incentives, and standards. Formed to coordinate and link academic and commercial biomedical researchers through Commons that represents new paradigm for genomics intellectual property, researcher cooperation, and contributor evolved resources. bionetwork, medical, research, human, treatment, disease, biological, biomedical, genomic, development, diagnostic, therapeutic, molecular, meta-data, model, clinical, bioinformatics, drug, consortium, data sharing, software is listed by: Consortia-pedia
is parent organization of: CommonMind Consortium
is parent organization of: Sage Bionetworks Podcasts
is parent organization of: Key Driver Analysis
is parent organization of: Synapse
Free, Freely available Wikidata: Q891621, nif-0000-32903, grid.430406.5, SCR_004425, ISNI: 0000 0004 6023 5303, nlx_42820 https://ror.org/049ncjx51 http://sagebase.org/commons/repository.php SCR_003384 2026-09-12 12:55:57 119
VISN 4 MIRECC
 
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VISN 4 MIRECC (RRID:SCR_001970) VISN 4 MIRECC data or information resource, funding resource, organization portal, portal, training resource The mission of the VISN 4 MIRECC is the treatment and prevention of comorbid medical, mental health, and/or substance use disorders, with the aim of improving the health, quality of life, and outcomes of healthcare services for veterans with mental illness. This is accomplished through the integration of basic, clinical, and services research and educational and clinical programs. The objectives of this MIRECC are: * Develop new empirical knowledge that can be directly applied to improve the clinical care of veterans * Provide education to providers and trainees to enhance the delivery of high quality healthcare to veterans * Impact public health in terms of veterans' mental health and quality of life * Serve as a national resource in education, research, and treatment of patients with comorbidity, and as a replicable model of excellence in clinical and educational programs Examine causal factors in the development of comorbid conditions. Assess impact of comorbidity on: * the identification and classification of disorders * the development and implementation of treatments * access to treatment and the impact of treatments on outcomes Sponsors: This work is supported by the US Department of Veterans Affairs educational, clinical, comorbidity, disorder, medical, mental health, prevention, substance use disorder, treatment nif-0000-10541 SCR_001970 The Stars and Stripes Healthcare Network (VISN 4) Mental Illness Research, Education and Clinical Center 2026-09-12 12:55:35 0
WebPath - The Internet Pathology Laboratory for Medical Education
 
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WebPath - The Internet Pathology Laboratory for Medical Education (RRID:SCR_002033) data or information resource, narrative resource, training material This popular web resource includes over 1900 images along with text, tutorials, laboratory exercises, and examination items for self-assessment that demonstrate gross and microscopic pathologic findings associated with human disease conditions. Content includes pathology cases (surgical pathology, autopsy, cytopathology, forensic pathology, clinical pathology) at the University of Utah Health Sciences Center and affiliated hospitals and laboratories, and from contributors at other institutions worldwide. The content at this web site will assist a medical student in achievement of an important goal: passing step 1 of the USMLE examination required to become licensed as a physician. This site was conceived from the necessity to create useful multimedia teaching resources for medical students at the University of Utah for use in the pathology courses given in the second year of the curriculum. examinations, general, aids, anatomy, clinical, disease, histology, human, images, laboratory exercises, medical education, pathology, systemic, text, tutorials Free, Freely available nif-0000-11854 SCR_002033 WebPath 2026-09-12 12:55:36 0
DMET-Analyzer
 
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1+ mentions
DMET-Analyzer (RRID:SCR_002030) DMET-Analyzer software resource Software tool for the automatic association analysis among the variation of the patient genomes and the clinical conditions of patients, i.e. the different response to drugs. The system allows: (i) to automatize the workflow of analysis of DMET (drug metabolism enzymes and transporters)-SNP (Single Nucleotide Polymorphism) data avoiding the use of multiple tools; (ii) the automatic annotation of DMET-SNP data and the search in existing databases of SNPs (e.g. dbSNP), (iii) the association of SNP with pathway through the search in PharmaKGB, a major knowledge base for pharmacogenomic studies. It has a simple graphical user interface that allows users (doctors/biologists) to upload and analyze DMET files produced by Affymetrix DMET-Console in an interactive way. drug, metabolism, enzyme, transporter, affymetrix, variation, genome, clinical, affymetrix dmet, single nucleotide polymorphism, annotation, analysis, pharmacogenomic, pathway is listed by: OMICtools
has parent organization: SourceForge
PMID:23035929 Free, Available for download, Freely available OMICS_01920 SCR_002030 DMETANALYZER, DMETANALYZER - A tool for supporting pharmacogenomics data analysis 2026-09-12 12:55:36 1
NIDA Data Share
 
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10+ mentions
NIDA Data Share (RRID:SCR_002002) catalog, data or information resource, data repository, database, service resource, storage service resource Website which allows data from completed clinical trials to be distributed to investigators and public. Researchers can download de-identified data from completed NIDA clinical trial studies to conduct analyses that improve quality of drug abuse treatment. Incorporates data from Division of Therapeutics and Medical Consequences and Center for Clinical Trials Network. drug of abuse, clinical, data, data sharing, human, clinical trial, experimental protocol, addiction, drug, addiction, data set, substance abuse is used by: NIF Data Federation
is used by: Integrated Datasets
is used by: NIH Heal Project
is recommended by: National Library of Medicine
is recommended by: BRAIN Initiative
is listed by: re3data.org
is related to: NIDA Networking Project: Facilitating information exchange and research collaboration
is related to: Integrated Manually Extracted Annotation
has parent organization: National Drug Abuse Treatment Clinical Trials Network
NIDA Restricted nif-0000-21981 http://www.ctndatashare.org/ SCR_002002 NIDA Clinical Trials Data Share, CTN database, CTN Data Share, NIDA CTN Data Share 2026-09-12 12:55:35 25
University of California at San Diego, School of Medicine: Graduate Opportunities & Dual Degree Programs
 
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1+ mentions
University of California at San Diego, School of Medicine: Graduate Opportunities & Dual Degree Programs (RRID:SCR_001942) data or information resource, degree granting program, medical school program resource, organization portal, portal, training resource The UCSD School of Medicine are dedicated to producing future leaders in all areas of medicine. As such, the School promotes the pursuit of dual degrees, either in the Medical School's own graduate degree programs or programs offered in other disciplines in the institution. In addition to the study of medicine, the School of Medicine actively encourages its student body to explore broadly in various scholarly areas related to the biomedical sciences. The goal of this additional training is to produce graduates who will bring fresh, innovative ideas to the research laboratory, the public health sector, the humanities and the social sciences, and the business environment. Students may elect to obtain advanced degrees in the following areas: * Biomedical Sciences * Masters in Bioengineering * Masters in Public Health * Masters in Leadership of Health Care Organizations * Masters of Advanced Studies in Clinical Research * Ph.D. Program in the Humanities and Social Sciences * Independent Ph.D. programs Opportunities for enrollment in research or degree programs outside of UCSD are also available, and students are encouraged to investigate these, if interested. Sponsors: This program is supported by the University of California at San Diego. dual degree program, bioengineering, biomedical science, business, clinical, graduate program, health care, humanity, medicine, public health, social science nif-0000-10519 http://cybermed.ucsd.edu/asa/goddp/ SCR_001942 UCSD Graduate Programs 2026-09-12 12:55:34 1
International Neuroinformatics Coordinating Facility
 
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50+ mentions
International Neuroinformatics Coordinating Facility (RRID:SCR_002282) INCF nonprofit organization Independent international facilitator catalyzing and coordinating global development of neuroinformatics aiming to advance data reuse and reproducibility in global brain research. Integrates and analyzes diverse data across scales, techniques, and species to understand brain function and positively impact the health and well being of society. neuroinformatics, neuroscience, neuroimaging, clinical, brain, data, sharing, reuse, global is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Spike Sorting Evaluation Project
is related to: Allen Brain Atlas API
is related to: SenseLab
has parent organization: Karolinska Institute; Stockholm; Sweden
has parent organization: Royal Institute of Technology; Stockholm; Sweden
is parent organization of: INCF Dataspace
is parent organization of: Waxholm Space
is parent organization of: MUlti SImulation Coordinator
is parent organization of: INCF Software Center
is parent organization of: Program on Ontologies of Neural Structures
is parent organization of: Common Upper Mammalian Brain Ontology
is parent organization of: INCF Training in Neuroinformatics
is parent organization of: INCF Funding
is parent organization of: INCF Blog
is parent organization of: INCForg - YouTube
is parent organization of: INCF Swiss Node
is parent organization of: INCF Newsroom
is parent organization of: INCF Japan Node
is parent organization of: Scalable Brain Atlas
is parent organization of: INCF Job Board
is parent organization of: INCF Neuroimaging Data Sharing
is parent organization of: Waxholm Space
is parent organization of: NeuroLex
is parent organization of: Neuroimaging Data Model
is parent organization of: Neuron Registry Curator Interface
is parent organization of: INCF-Neurobot
NSF ;
Swedish Foundation for Strategic Research ;
Swedish Research Council
ISNI: 0000 0004 6107 939X, grid.498423.0, nif-0000-00365 https://ror.org/02y5xjh56 SCR_002282 INCF, International Neuroinformatics Coordinating Facility, The International Neuroinformatics Coordinating Facility 2026-09-12 12:55:39 63
Washington University School of Medicine Neuroscience Tutorial
 
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Washington University School of Medicine Neuroscience Tutorial (RRID:SCR_002271) Neuroscience Tutorial curriculum material, data or information resource, image collection, narrative resource, training material An illustrated guide to the essential basics of clinical neuroscience created in conjunction with the first-year course for medical students.
Topics covered:
* Coronal and horizontal sections
* Basic visual pathway
* Basic somatosensory pathway
* Basic motor pathway
* Eye and retina
* Central visual pathways
* Auditory and vestibular systems
* Somatosensory pathways from the body
* Somatosensory pathways from the face
* Spinal motor structures
* Brainstem nuclei of cranial nerves
* Basal ganglia and cerebellum
* Hypothalamus and autonomic nervous system
* Medial temporal lobe and memory
* Sleep and language
* Where is...?
clinical neuroscience, clinical, neuroscience, brain, neuroanatomy, coronal, horizontal, visual pathway, somatosensory pathway, motor pathway, eye, retina, auditory system, vestibular system, spinal motor, brainstem nuclei of cranial nerve, basal ganglia, cerebellum, hypothalamus, autonomic nervous system, medial temporal lobe, memory, sleep, language has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA nif-0000-00113 http://thalamus.wustl.edu/course SCR_002271 2026-09-12 12:55:38 0
Autosomal Recessive Polycystic Kidney Disease Mutation Database
 
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10+ mentions
Autosomal Recessive Polycystic Kidney Disease Mutation Database (RRID:SCR_002290) data or information resource, data repository, database, service resource, storage service resource Catalog of all changes detected in PKHD1 (Polycystic Kidney and Hepatic Disease 1) in a locus specific database. Investigators are invited to submit their novel data to this database. These data should be meaningful for clinical practice as well as of relevance for the reader interested in molecular aspects of polycystic kidney disease (PKD). There are also some links and information for ARPKD patients and their parents. Autosomal recessive polycystic kidney disease (ARPKD/PKHD1) is an important cause of renal-related and liver-related morbidity and mortality in childhood. This study reports mutation screening in 90 ARPKD patients and identifies mutations in 110 alleles making up a detection rate of 61%. Thirty-four of the detected mutations have not been reported previously. Two underlying mutations in 40 patients and one mutation in 30 cases are disclosed, and no mutation was detected on the remaining chromosomes. Mutations were found to be scattered throughout the gene without evidence of clustering at specific sites. PKHD1 mutation analysis is a powerful tool to establish the molecular cause of ARPKD in a given family. Direct identification of mutations allows an unequivocal diagnosis and accurate genetic counseling even in families displaying diagnostic challenges. clinical, gene, genetic, mutation, protein, recessive, renal has parent organization: RWTH Aachen University; Aachen; Germany Autosomal recessive polycystic kidney disease, Polycystic kidney disease PMID:16199545
PMID:11919560
Permission required, Terms of use nif-0000-21038 http://www.humgen.rwth-aachen.de/index.asp?subform=database.html&nav=database_nav.html SCR_002290 Mutation Database Autosomal Recessive Polycystic Kidney Disease (ARPKD/PKHD1) 2026-09-12 12:55:39 14
College on Problems of Drug Dependence
 
Resource Report
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College on Problems of Drug Dependence (RRID:SCR_002618) CPDD data or information resource, journal article, meeting resource, narrative resource, portal, service resource, topical portal, training material, training resource, training service resource The College on Problems of Drug Dependence (CPDD) is an interdisciplinary research society whose members address problems of drug dependence in the broadest range of scientific disciplines, including chemistry, basic biology, pharmacology, behavioral science, clinical research, sociology, psychology, anthropology, and history. CPDD serves as an interface among governmental, industrial and academic communities maintaining liaisons with regulatory and research agencies as well as educational, treatment, and prevention facilities in the drug abuse field. It also functions as a collaborating center of the World Health Organization. The Annual Scientific Meeting: Since 1938, a major focus of the CPDD's activities has been its sponsorship of an annual scientific meeting. This conference serves as a forum bringing together basic scientists and clinical investigators from industry, academia, and government. Representatives of regulatory agencies, as well as scientists and professionals in a number of diverse disciplines interested in the biochemical, behavioral, and public health aspects of drug dependence participate. Special Conferences: Periodically, the College sponsors conferences focused on timely topics of interest to researchers, government, industry, and the public. In recent years, CPDD has organized meetings on Abuse Liability Assessment of CNS Drugs; Drug Formulation and Abuse Liability; Pre-Clinical Abuse Liability Testing; Women and Smoking: Understanding Socioeconomic Influences; and Risk Management and Post-Marketing Surveillance for CNS-Acting Drugs. Consultation Activities: The CPDD provides consulting expertise in the area of epidemiology, treatment, prevention, and all the basic and clinical sciences related to drug dependence, drug abuse, and their behavioral and medical consequences. Sponsorship of Drug and Alcohol Dependence: The CPDD sponsors the journal Drug and Alcohol Dependence, published by Elsevier. A principal goal of the journal is to provide a source of quality, timely reports of scientific advances in substance abuse research. The journal is international in scope and interdisciplinary in coverage. The CPDD invites contributors. Donations Tax-deductible donations can be made to CPDD to support the Annual Scientific Meeting, testing facilities, drug assessment activities and Awards for Excellence. drug, drug abuse, drug dependence, educational opportunity, epidemiology, fact sheets, fellowship, funding, alcohol, animal, anthropology, basic, basic biology, behavioral, behavioral science, biochemical, chemistry, clinical, clinical research, consulting, history, job, medical consequences, opioids, pharmacology, pharmacotherapy, prevention, psychology, public health, research, society, sociology, substance abuse, tobacco, treatment has parent organization: Virginia Commonwealth University; Virginia; USA Free nif-0000-21909 SCR_002618 Committee on Problems of Drug Dependence 2026-09-12 12:55:43 0
Grinder
 
Resource Report
Resource Website
1+ mentions
Grinder (RRID:SCR_000168) Grinder software resource An open-source bioinformatic tool to create simulated omic shotgun and amplicon sequence libraries for all main sequencing platforms. The tool is available through multiple interfaces like GUI, CLI and API. It is useful for simulating clinical or environmental microbial communities and complements the use of in vitro mock communities. simulation, amplicon, shotgun, genomic sequencing, clinical, metagenomic, transcriptomic and metatranscriptomic is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
PMID:22434876
DOI:10.1093/nar/gks251
Free, Available for download, Freely available OMICS_01508 https://sources.debian.org/src/grinder/ SCR_000168 2026-09-12 12:55:04 3
World Health Organization: The Global Health Library
 
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1+ mentions
World Health Organization: The Global Health Library (RRID:SCR_000391) bibliography, data or information resource, portal, topical portal The Global Health Library assembles health data, readable in many languages. The GHL aims to: * point to reliable information collections and systems, in which different users and user groups (ministries of health, policy makers, health workers, information providers, patients and their families, general public) can focus on the knowledge that best meets their health information needs; * act as a facilitator enabling access to information contents produced by numerous key providers - be they commercial companies, government institutions, civil society, not-for-profit organizations, and regional or international bodies; and * strive for universality, with focus on developing countries, and will act as a resource locator for print materials essential to areas that do not have access to electronic content. clinical, health, human, people has parent organization: World Health Organization THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10556 http://www.who.int/ghl/en/ SCR_000391 GHL 2026-09-12 12:55:08 2
ALS Association
 
Resource Report
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10+ mentions
ALS Association (RRID:SCR_000442) ALS Association nonprofit organization Established in 1985, The ALS Association is the only national non-profit organization fighting Lou Gehrig's Disease on every front. By leading the way in global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships, The Association builds hope and enhances quality of life while aggressively searching for new treatments and a cure. As the preeminent ALS organization, The Association leads the way in research, care services, public education, and public policy giving help and hope to those facing the disease. The Association's nationwide network of chapters provides comprehensive patient services and support to the ALS community. The mission of The ALS Association is to lead the fight to treat and cure ALS through global research and nationwide advocacy, while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support. The ALS Association has committed more than $58 million to find effective treatments and a cure for Lou Gehrig's Disease. Our global research effort has helped increase the number of scientists working on ALS, advanced new discoveries and treatments, and has shed light on the complex genetic and environmental factors involved in ALS. Diversity exemplifies The ALS Association's research philosophy. The Association spearheads investigator-initiated projects that originate from the minds of scientists. It also has ALS Association-initiated projects in which research ideas come from a small, blue ribbon committee of scientists who reach out with specific projects for designated scientists in the field. The ALS Association offers multi-year grants to established investigators, as well as one-year starter research awards. The Association is proud to administer The Milton Safenowitz Post-Doctoral Fellowship for ALS Research, which is the only post-doctoral fellowship for ALS research. In addition, The ALS Association's Sheila Essey Award, the premier ALS award, recognizes achievement in research. The ALS Association holds workshops each year that bring together scientists researching ALS and other neurodegenerative diseases to generate new research suggestions and fresh insight. In addition, our TREAT ALS (Transitional Research Advancing Therapy for ALS) initiative combines efficient new drug discovery with priorities set for existing drug candidates to accelerate clinical testing of compounds with promise for the disease. Our Clinical Management Research Program focuses on managing the care of people with ALS in such areas as nutrition, respiration, mobility and psychosocial needs. Since 1998, The Association has funded 21 clinical management research projects representing a total commitment of $750,000. The Association produces a series of manuals and videos as well as a DVD, called Living with ALS, that educate patients about all aspects of the disease. research, clinical care center, treatment, cure, care service, public education, public policy, post-doctoral fellowship, clinical, grant, award Amyotrophic Lateral Sclerosis nif-0000-00449, Wikidata: Q4652439, grid.430438.8, ISNI: 0000 0004 0590 7963, Crossref funder ID: 100000971 https://ror.org/00mwp5989 SCR_000442 Amyotrophic Lateral Sclerosis Association, ALS Association - Fighting Lou Gehrig's Disease, ALS Association 2026-09-12 12:55:09 11
Jefferson Hospital for Neuroscience Alzheimers Disease and Dementia Center
 
Resource Report
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Jefferson Hospital for Neuroscience Alzheimers Disease and Dementia Center (RRID:SCR_000579) Jefferson Alzheimer's Disease and Dementia Center data or information resource, disease-related portal, patient-support portal, portal, topical portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 6,2023. If you or someone you love has been diagnosed with dementia caused by Alzheimer's disease, you'll be in good hands at Jefferson. Our neurologists and psychiatrists are dedicated to: Compassionate care for individuals with Alzheimer's disease; Supporting families; Advancing care through research into the epidemiology and treatment of neurodegenerative diseases. We interact with patients very early in the disease progression, when impairment is typically mild; deliver state-of-the-art care; provide information; build care-giving skills; and help caregivers connect with community support and plan for the future. alzheimer's disease, late adult human, neurodegenerative disease, dementia, brain bank, clinical trial, clinical has parent organization: Thomas Jefferson University; Pennsylvania; USA THIS RESOURCE IS NO LONGER IN SERVICE nlx_144497 http://www.jeffersonhospital.org/departments-and-services/alzheimers-disease-dementia-center.aspx SCR_000579 Jefferson Hospital for Neuroscience Alzheimers Disease Dementia Center, Jefferson Hospital for Neuroscience Alzheimer's Disease Dementia Center, Jefferson Hospital for Neuroscience Alzheimer's Disease and Dementia Center 2026-09-12 12:55:11 0
VariantMaster
 
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VariantMaster (RRID:SCR_000569) VariantMaster software resource Software program that extracts causative variants in familial and sporadic genetic diseases. The algorithm takes into account predicted variants (SNPs and indels) in affected individuals or tumor samples and utilizes the row (BAM) data to robustly estimate the conditional probability of segregation in a family, as well as the probability of it being de novo or somatic. In familial cases, various modes of inheritance are considered: X-linked, autosomal dominant, and recessive (homozygosity or compound heterozygosity). Moreover, it integrates phenotypes and genotypes, and employs Annovar to produce additional information as allelic frequencies in general population and damaging scores. unix/linux, clinical, genetics, high throughput sequencing, monogenic disease, variant, snp, indel is listed by: OMICtools
has parent organization: SourceForge
Genetic disease, Tumor PMID:24389049 Free, Available for download, Freely available, OMICS_02261 SCR_000569 VariantMaster - Extract causative variants for monogenic and sporadic genetic diseases 2026-09-12 12:55:11 0
Cystic Fibrosis Mutation Database
 
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10+ mentions
Cystic Fibrosis Mutation Database (RRID:SCR_000685) CFTR1, CFMDB data or information resource, data repository, database, service resource, storage service resource Collection of mutations in CFTR gene for international cystic fibrosis genetics research community. Provides up to date information about individual mutations in CFTR gene. All known CFTR mutations and sequence variants have been converted to standard nomenclature recommended by Human Genome Variation Society. On line process for submission of new mutations has been added.While they continue to ensure quality of data, they urge international community to give them feedback and suggestions. Clinical information in this database relates only to details of discovery of specific mutations. As part of 2010 upgrade, CFTR1 joined new project called CFTR2 - Clinical and Functional TRanslation of CFTR. Links to CFTR2 for many mutations in CFTR1 will provide up-to-date summaries of genotype-phenotype information from patient registries around the world. Gene, genetic, amino acid, clinical, cystic fibrosis, mutation, phenotype, genotype-phenotype, genotype, dna sequence, mouse, sequence, genetic variation, polymorphism, translation, function, sequence variation, metadata standard, cftr2, FASEB list is related to: CFTR2 Cystic fibrosis Free, Freely available nif-0000-21105, r3d100012093 https://doi.org/10.17616/R38356 SCR_000685 2026-09-12 12:55:13 42
NIH - Rapid Access to Interventional Development
 
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1+ mentions
NIH - Rapid Access to Interventional Development (RRID:SCR_000713) analysis service resource, biomaterial analysis service, biomaterial manufacture, funding resource, material analysis service, material service resource, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 14, 2025.NIH-RAID makes available at no cost to researchers and organizations certain critical resources needed for the development of new therapeutic agents. This program, part of the Translational Research component of Reengineering the Clinical Research Enterprise, uses resources of NCI's Developmental Therapeutics Program and the National Heart Lung and Blood Institutes (NHLBI) Gene Therapy Resource Program. The services provided will depend upon the stage of the project and the strength of the preliminary data. Services available include: production, bulk supply, GMP manufacturing, formulation, development of an assay suitable for pharmacokinetic testing, and animal toxicology. Assistance also will be provided in the regulatory process, through access to independent product development planning expertise. Proposals in support of animal efficacy studies or synthesis and formulation of recombinant proteins or monoclonal antibodies will not be accepted. NIH-RAID is not a grant program. Successful projects will gain access to the governments contract resources, as well as the assistance of the NIH in establishing and implementing a product development plan. Funds to support individual projects will come both from the Roadmap and from individual Institutes, with Institutes assuming the bulk of support in the specific disease areas germane to their mission. This co-sponsorship is critical because of the resource and expertise needs and because NIH-RAID cannot support the full developmental pipeline; an Institute partnership may therefore be important for subsequent translational efforts. To obtain access to NIH-RAID resources, applications must be submitted electronically through Grants.gov using SF424. Applications are initially screened to determine whether the resources requested are appropriate for this program. Then they are reviewed by the NIH Center for Scientific Research. The results of that evaluation along with supplemental information from the lead investigator will guide final Institute and Roadmap resource allocation. The services provided will depend upon the stage of the project and the strength of the preliminary data. When a lead therapeutic agent has been selected and proposed for preclinical development, the following services are available: For small molecules, natural products, peptides, oligonucleotides, and gene vectors: Synthesis, Scale-up production, Development of analytical methods, Development of suitable formulations, Isolation and purification of natural products, Pharmacokinetic/ADME studies including bioanalytical method development, Range-finding initial toxicology, IND-directed toxicology, Manufacture of clinical trial supplies, Product development planning and advice in IND preparation For recombinant proteins and monoclonal antibodies: Pharmacokinetic/ADME studies including bioanalytical method development, Range-finding initial toxicology, IND-directed toxicology, Product development planning and advice in IND preparation When a lead therapeutic agent has not yet been selected and proposed for preclinical development, the following services are available: For small molecules, natural products, peptides, oligonucleotides, and gene vectors: Synthesis, Development of analytical methods, Isolation and purification of natural products, Preliminary Pharmacokinetic/ADME studies, including bioanalytical method development, Preliminary toxicology For recombinant proteins and monoclonal antibodies, Preliminary Pharmacokinetic/ADME studies, including bioanalytical method development, Preliminary toxicology In some cases the NIH-RAID program will support only one or two key steps for preclinical development, while in other cases it may be possible to provide assistance with most of the development tasks needed to file an Investigational New Drug (IND) application to the Food and Drug Administration (FDA). When the NIH-RAID program does not provide all of the remaining services required for IND submission, it is expected that other resources will be in place to complete development steps not supported by NIH-RAID. Funding Resource,. adme, applied, biomaterial method development, clinical, pharmacology, student, toxicology THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00543 http://nihroadmap.nih.gov/raid/ SCR_000713 NIH-RAID 2026-09-12 12:55:14 1
Online Education for the International Research Community: AboutIntroduction to Clinical Drug and Substance Abuse Research Methods
 
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Online Education for the International Research Community: AboutIntroduction to Clinical Drug and Substance Abuse Research Methods (RRID:SCR_000802) certificate program, continuing medical education, short course, training resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on November 07, 2012. Decemeber 15, 2011 - Thank you for your interest in DrugAbuseResearchTraining.org. The site, courses, and resources are no longer available. Please send an email to inquiry (at) md-inc.com if you would like to be notified if the site or courses become available again. Introduction to Clinical Drug and Substance Abuse Research Methods is an online training program intended to introduce clinicians and substance abuse professionals to basic clinical research methods. The program is divided into four modules. Each module covers an entire topic and includes self-assessment questions, references, and online resources: * The Neurobiology of Drug Addiction * Biostatistics for Drug and Substance Abuse Research * Evaluating Drug and Substance Abuse Programs * Designing and Managing Drug and Substance Abuse Clinical Trials The learning objectives of this program are to help you: * Evaluate the benefits of alternative investigative approaches for answering important questions in drug abuse evaluation and treatment. * Define the proper levels of measurement and appropriate statistical methods for a clinical study. * Address common problems in data collection and analysis. * Anticipate key human subjects and ethical issues that arise in drug abuse studies. * Interpret findings from the drug abuse research literature and prepare a clinical research proposal. * Prepare research findings for internal distribution or publication in the peer reviewed literature. * Recognize drug addiction as a cyclical, chronic disease. * Understand and describe the brain circuits that are affected by addicting drugs, and explain to others the effects of major classes of addicting drugs on brain neurotransmitters. * Utilize new pharmacologic treatments to manage persons with drug addiction. Physicians can earn AMA PRA Category 1 Credit and purchase a high resolution printable electronic CME certificate(view sample); non-physicians can purchase high resolution printable electronic certificate of course participation that references AMA PRA Category 1 credit (view sample). This program does not offer printed certificates. clinical, drug, substance abuse, research, course, clinician, neurobiology, addiction, literature, disease, brain, circuit, neurotransmitter, pharmacologic, treatment, education, training NIDA THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-37940 SCR_000802 Neurobiology of Addiction Online Course 2026-09-12 12:55:15 0
Viral Immunology Center
 
Resource Report
Resource Website
Viral Immunology Center (RRID:SCR_001089) data or information resource, disease-related portal, laboratory portal, organization portal, portal, research forum portal, topical portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2025. The National B Virus Resource Center is located in the Viral Immunology Center of Georgia State Universitys Department of Biology. Their laboratory is studying viruses that directly affect the central nervous system of infected hosts. Current projects in the laboratory are focused on the molecular biology of human and nonhuman primate alphaherpesviruses and the diseases they cause, immune response characterization, antiviral strategies, including drug discovery and high-throughput drug screening within unique, high containment laboratory suites. They are also actively engaged in the study of unique reoviruses that have the capacity to infect the central nervous systems of non human primates, langur viruses, and a newly isolated mangaby herpesvirus. Alphaherpesviruses target the central nervous system of susceptible hosts, and subsequently establish latent infections generally without severely damaging the host. There may be an initial acute phase when the virus successfully replicates in peripheral tissue of the host. This replication, when it occurs, induces a series of specific immune functions that can serve as markers of infection. We use these markers to design, develop and implement diagnostic assays that will be useful during the management of clinical disease. Each herpesvirus coexists peacefully with the natural host in which it has co-evolved, but when the viruses for any reason find themselves no longer in the natural host, the usual host:parasite relationship may change dramatically. In some closely related hosts the virus can replicate and, in some cases, pathogenesis of the infection is radically more severe than that which occurs in the natural host. For example, this can be seen when New World monkeys are infected with humans herpesviruses, e.g., HSV-1 or HSV-2, or when humans are infected with B virus from a macaque, a member of the Old World monkey family. Their studies focus on the mechanisms by which virus kills the host and how that process can be circumvented with early identification, appropriate antiviral drugs, and in the future, effective vaccines. We continually screen the efficacy of existing as well as novel antiviral agents to inhibit the growth of viruses that can potentially cross into the human population, either through occupational exposure or through more subtle contact. Their laboratory provides a global resource funded by National Institutes of Healths National Center for Research Resources to assist in the identification of zoonotic disease transmissions and develop enhanced strategies to detect virus in macaques. They particularly focus on the transmission of B virus from Asian monkeys to humans who come in contact with them. Members of the genus Macaca include rhesus monkeys, cynomolgus macaques, snow macaques, as well as all other macaques. If the macaque is in the midst of the acute or recurrent infection with B, virus can be transmitted to people who handle these monkeys through cuts, scratches, splashes, bites, or even contaminated equipment or surfaces, i.e., fomites. To counter the effects of this virus, the NIH and Centers for Disease Control and Prevention have instituted a critical set of guidelines for institutions to follow in the event of exposures. Their laboratory provides immediate support to these cases to assist in the rapid diagnosis of B virus infections and to determine the efficacy of selected treatment. Lifetime patient monitoring is provided to identify possible reactivation disease and to better track this unique herpesvirus as it has begun its existence in the human populations. Sponsors: The viral immunology center is funded by National Institutes of Healths National Center for Research Resources. drug, acute, agent, alphaherpesvirus, antiviral, biology, b virus, center, central, clinical, cynomolgus, disease, herpes, host, hsv-1, hsv-2, human, immune, immunology, infect, infection, langur, macaque, mangaby, molecular, monkey, nervous system, nonhuman, parasite, pathogenesis, population, primate, reovirus, replicate, response, screening, snow, viral, virus THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-24367 SCR_001089 Viral Immunology Center 2026-09-12 12:55:19 0

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