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Center for advancing scientific understanding and improving the health and well-being of humans and nonhuman primates. The Center conducts research in microbiology and immunology, neurologic diseases, neuropharmacology, behavioral, cognitive and developmental neuroscience, and psychiatric disorders.
Proper citation: Yerkes National Primate Research Center (RRID:SCR_001914) Copy
http://hendrix.ei.dtu.dk/software/mriwarp/mriwarp.html
Warping tool for intersubject registration of brain images consisting of C functions for Unix systems plus Matlab visualization utility functions. Apart from warping there are also (command line) functions for ANALYZE header information, mirroring, translation, subsampling. The package cannot only be used as a preprocessing step in function neuroimaging but also as a step in deformation-based morphometry.
Proper citation: MRIWarp (RRID:SCR_002072) Copy
Computational neuroscience center that observes and models how functional activities in multiple brain areas interact dynamically to support human cognition, creativity and social interaction. Center research involves development computational methods and software, experimental methods and equipment, collection and analysis of human cognitive experiments, and collaborations to analyze data collected by other groups in such experiments. The Center has a 72-channel EEG recording system customized for use in the fMRI environment, and a very-high density Biosemi Active Two active-electrode EEG system, rapidly configurable either as a 256-channel system for a single subject or as two 136-channel systems for recording from two subjects simultaneously. In addition, UCSD now has a 306-channel MEG plus 128-channel EEG system (Neuromag/Elektra). Projects in the Center include studies of human cognitive processes including attention and memory, role of the anterior/posterior cingulate, time perception and emotional expression. Data acquisition includes high-density EEG, concurrent EEG and fMRI recording and analysis, and face video processing. Current analysis approaches include independent component and time-frequency analysis.
Proper citation: Swartz Center for Computational Neuroscience (RRID:SCR_001933) Copy
http://www.pc.rhul.ac.uk/staff/J.Larsson/software.html
Set of programs and Tk/Tcl scripts, with a GUI wrapper, for extracting the inner and outer cortical surfaces from a T1-weighted MR image of the human brain. It is based on the TFI C++ library and is written for a Unix-based environment (specifically 64-bit and 32-bit versions of Ubuntu). As a courtesy to Apple users a version for Apple/X11 is maintained but the OS X version will always lag the Linux version; also, because some of the third-party libraries SurfRelax relies on may not be supported in or compatible with future versions of OS X, there is no guarantee that the OS X version will be supported indefinitely. Although in principle SurfRelax could be run under Windows (using Cygwin), because of the difficulties of maintaining multiple platforms and the limited support libraries available under Cygwin, there will no longer be support for SurfRelax on this platform. The surfaces are guaranteed to be topologically equivalent to a sphere, thereby obviating the need for handle removal. SurfRelax requires no user intervention, although minor manual editing is recommended for optimal results (normally less than 10 minutes per hemisphere). SurfRelax has several properties that compare favorably with other software packages for surface reconstruction: * Free software - The binaries (written in C++ and Tcl/Tk) are in the public domain. The source code will be released once legacy code issues have been resolved (i.e. replacing with GPL code). * Uses standard public file formats: Analyze file format (SPM/FSL-compatible) for volumes and OOGL OFF binary format for surfaces (see www.geomview.org (http://www.geomview.org/docs/html/geomview_26.html#OOGLRef)) * Combines advantages of volumetric and surface-based methods for surface generation * Correct topology of output surface guaranteed * Requires little or no user intervention - no need for manual handle removal * Relatively robust to noise - multi-scale method compensates for partial volume effects and intensity inhomogeneities * Relatively fast (an entire brain is segmented, extracted and unfolded in less than 2 hours of CPU time) * Powerful editing and visualization tools for volumes and surfaces * Readily extendable - for instance for use with monkey brains or children's brains * Can be used to visualize functional data from SPM or FSL * Includes tools for integration with Stanford's VISTASOFT tools for FMRI data analysis (white.stanford.edu)
Proper citation: SurfRelax (RRID:SCR_002139) Copy
Independent international facilitator catalyzing and coordinating global development of neuroinformatics aiming to advance data reuse and reproducibility in global brain research. Integrates and analyzes diverse data across scales, techniques, and species to understand brain function and positively impact the health and well being of society.
Proper citation: International Neuroinformatics Coordinating Facility (RRID:SCR_002282) Copy
http://www.bioon.com/bioline/neurosci/course/index.htm
An illustrated guide to the essential basics of clinical neuroscience created in conjunction with the first-year course for medical students.
Topics covered:
* Coronal and horizontal sections
* Basic visual pathway
* Basic somatosensory pathway
* Basic motor pathway
* Eye and retina
* Central visual pathways
* Auditory and vestibular systems
* Somatosensory pathways from the body
* Somatosensory pathways from the face
* Spinal motor structures
* Brainstem nuclei of cranial nerves
* Basal ganglia and cerebellum
* Hypothalamus and autonomic nervous system
* Medial temporal lobe and memory
* Sleep and language
* Where is...?
Proper citation: Washington University School of Medicine Neuroscience Tutorial (RRID:SCR_002271) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 28,2025. Project mapping whole mouse brain connectivity using serial block face scanning electron microscopy (SBF-SEM) with a specially-designed whole-brain microtome (WBM). With any luck, the whole mouse brain will be mapped ultrastructurally in the near term, which will then open the door to more serious problems; reliable automated segmentation and circuit reconstruction. These will undoubtedly require advances in machine learning methods and their application. Connectomics Software and a Multiresolution Image Viewer (MIV) is also available.
Proper citation: Connectomes.org (RRID:SCR_002243) Copy
http://www.kumc.edu/instruction/medicine/anatomy/histoweb/nervous/nervous.htm
Histology atlas of different parts of the nervous system that corresponds with the laboratory exercises of the Cell & Tissue Biology course of the School of Medicine of the University of Kansas. Succinct explanations of the tissues to guide the first-year medical student in the use of their microscope is provided and subsequently serves as a permanent histology resource for all medical students and physicians. Sections of the brain that are included are: * Spinal Cord * Central Canal * White Matter * Gray Matter * Dorsal Root Ganglion * Cerebellum * Cerebrum * Astrocytes * Nerve * Node of Ranvier * Pacinian Corpuscle
Proper citation: HistoWeb: Nervous System (RRID:SCR_002369) Copy
A network for supporting resting-state fMRI (R-fMRI) related studies. It connects R-fMRI researchers (as nodes) by their sharings (as edges). Through the network, ideas, comments, resources, tools, experiences, and data can be shared. Researchers (nodes) with basic neuroscience, methodological, or clinical backgrounds can connect with each other in the network. It also contains a preprint server that allows neuroscientists to share their preprints, comment on each others research and get back valuable information about their experiments from their colleagues. This is based on the arXiv model. Ultimately, the network aims to enhance collaborations among researchers, especially to translate knowledge of basic neuroscience and methodology to clinical applications (bench to bedside).
Proper citation: RFMRI.ORG (RRID:SCR_004042) Copy
The Center for Interdisciplinary Brain Sciences Research (CIBSR) at the Stanford University School of Medicine is dedicated to research that will improve the lives and well-being of individuals with disorders of the brain and improve knowledge of healthy brain and behavioral development. CIBSR research staff are dedicated to identifying biological and environmental risk factors, understanding disease pathophysiology and developmental outcomes, and developing new treatments for neurodevelopmental, neurogenetic and neuropsychiatric disorders of childhood onset. Our research studies are truly multi/interdisciplinary as they bring together experts from the fields of psychiatry, neurology, psychology, computer science, biostatistics and genetics to explore and seek answers for complex questions related to brain-behavior relationships. Active research at CIBSR includes: * Mutlimodal imaging of the brain utilizing anatomical and functional magnetic resonance imaging (MRI), diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS). * Behavioral, cognitive, and physiological assessment to address questions concerning the influence of biological and environmental factors on outcome. * The development of new biological and cognitive-behavioral treatments. * Development of brain image analysis methods and software.
Proper citation: Stanford University, Center for Interdisciplinary Brain Sciences Research (RRID:SCR_004134) Copy
Cre expressing mice under the control of promoters with a design focus on the brain. Each promoter is derived from human sequence, but the resulting expression is assessed in the mouse for the activation of a LacZ reporter gene by the Cre activity. Promoters tested as large MaxiPromoters (BACs inserted into the mouse genome) and MiniPromoters (plasmid-based sequences inserted either into the mouse genome or introduced within AAV viruses). The Cre-related project continues from the Pleiades Promoter Project. Here is the list of genes for which icre/ERT2 mice are currently in development: AGTR1, CARTPT, CLDN5, CLVS2, CRH, GABRA6, HTR1A, HTR1B, KCNA4, KDM5C, MKI67, NEUROD6, NKX6-1, NOV, NPY2R, NR2E1, OLIG2, POU4F2, SLITRK6, SOX1, SOX3, SOX9,, SPRY1, VSX2
Proper citation: CanEuCre (RRID:SCR_004159) Copy
https://www.uab.edu/medicine/alzheimers/
The UAB Alzheimer's Disease Center provides comprehensive treatment for Alzheimer's patients while also promoting research for the prevention and cure of Alzheimer's disease and related disorders. The ADC is an interdisciplinary program of scientists working in areas including neurology, psychiatry, genetics, and psychology. The Center provides comprehensive treatment and promotes research for the prevention and/or cure of Alzheimer's disease and other related disorders with memory loss and impaired cognition. A major emphasis of research is the maintenance of a clinical research database comprised of neurological, medical, and neuropsychological test data from participants seen in the ADRC Clinical study since 1999, many of whom have been followed for several years in the study.
Proper citation: UAB Alzheimer's Disease Center (RRID:SCR_004305) Copy
http://www.brainnet-europe.org/
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 7, 2022. Consortium of 19 brain banks across Europe with an aim to harmonize neuropathological diagnostic criteria and develop gold standards for quality, safety and ethics standards for brain banking. BrainNet Europe also contributes to research on rare diseases, such as: Pick''s disease or other rare forms of dementia, as well as to questions after the events in the aging brain. Anyone can be a donor - irrespective of disease of the central nervous system or not, because for research purposes, one does not only need tissue samples from ill donors, but also from healthy ones for comparison.
Proper citation: BrainNet Europe (RRID:SCR_004461) Copy
http://www.epilepsy.ie/index.cfm/spKey/research.html
Epilepsy Research Ireland is a non-profit organization (Charity CHY17527), run by a group of volunteers, who are dedicated to find cure for epilepsy by raising awareness and money for research. We can say cure now with much more confidence than we could even 10 years ago because recent advances in genetics, brain imaging and drug therapy, all hold out the promise of that holy grail the cure. We can also say with confidence that you can be part of that push by participating in this new foundation since we have collaborations with doctors and scientists all over Europe, the US and Australia, all of whom share the same goal. Epilepsy research, conducted by Epilepsy Research Ireland, is essential and will deliver benefits across the board. Research planned and already underway by Epilepsy Research Ireland will help develop and improve clinical skills; it will provide a knowledge base to develop new ways to manage and treat epilepsy; it will help in the evaluation of new medical advances. Ultimately we can improve the quality of care and provide greater understanding, better and more accurate diagnosis and more tailored treatments. Ireland is uniquely well-positioned, given its relatively homogenous population to make the goal, of making real discoveries in epilepsy research that will directly improve the lives of people with epilepsy, a realistic one.
Proper citation: Epilepsy Research Ireland (RRID:SCR_004448) Copy
Children''s Brain Tumor Foundation, a non-profit organization, was founded in 1988 by dedicated parents, physicians and friends. Our mission is to improve the treatment, quality of life and the long term outlook for children with brain and spinal cord tumors through research, support, education, and advocacy to families and survivors. Knowledge is critical for families to access expert care and ensure quality of life. Our free publication A Resource Guide for Parents of Children with Brain and Spinal Cord Tumors is now in its fourth edition, and is full of practical information to sort out the complexities of medical procedures, interruptions in school and social life, and uncertainty about the future. CBTF co-sponsors conferences for families, survivors and health care professionals, offering the latest information about research, treatments and strategies for living. Only scientific research will identify the causes and lead to effective treatments for brain tumors in children. CBTF funds cutting-edge research by scientists at top academic medical centers. Their discoveries hold the promise of improving the lives of affected children today and discovering the means of prevention for future generations. CBTF has awarded over $5 million in grants for basic and clinical research related to pediatric brain and spinal cord tumors. Also, over $625,000 has been given out in Quality of Life Grants.
Proper citation: Childrens Brain Tumor Foundation (RRID:SCR_004422) Copy
http://caintegrator-info.nci.nih.gov/rembrandt
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 28,2023. REMBRANDT is a data repository containing diverse types of molecular research and clinical trials data related to brain cancers, including gliomas, along with a wide variety of web-based analysis tools that readily facilitate the understanding of critical correlations among the different data types. REMBRANDT aims to be the access portal for a national molecular, genetic, and clinical database of several thousand primary brain tumors that is fully open and accessible to all investigators (including intramural and extramural researchers), as well as the public at-large. The main focus is to molecularly characterize a large number of adult and pediatric primary brain tumors and to correlate those data with extensive retrospective and prospective clinical data. Specific data types hosted here are gene expression profiles, real time PCR assays, CGH and SNP array information, sequencing data, tissue array results and images, proteomic profiles, and patients'''' response to various treatments. Clinical trials'''' information and protocols are also accessible. The data can be downloaded as raw files containing all the information gathered through the primary experiments or can be mined using the informatics support provided. This comprehensive brain tumor data portal will allow for easy ad hoc querying across multiple domains, thus allowing physician-scientists to make the right decisions during patient treatments., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Repository of molecular brain neoplasia data (RRID:SCR_004704) Copy
http://www.ukmstissuebank.imperial.ac.uk/news3d.html
Procures brain, spinal cord and other tissues bequeathed by donors and makes them available to scientists investigating the cause and treatment of multiple sclerosis. The Tissue Bank achieves this aim by addressing the following objectives: # Increasing the awareness of the importance of human tissue to research amongst the MS and scientific communities. # Being sensitive to the needs of the tissue donor and responsive to the requirements of scientists when collecting and processing donated tissue. # Making available high quality, well-documented samples of tissue to research scientists working to better understand MS. There are approximately 85 000 people with multiple sclerosis in the United Kingdom. The varied symptoms experienced by all these people result from damage taking place within their brain and spinal cord. Understanding the exact nature of this damage is essential if we are to better treat the condition. Vital information about how the brain and spinal cord are damaged in multiple sclerosis can be obtained by using a multitude of experimental approaches to study the affected tissue from people with MS and ''control'' tissue from people without the disease. The donation of tissue for research is therefore fundamental to furthering our understanding of the causes of multiple sclerosis and to developing more effective treatments for the disease. The UK Multiple Sclerosis Tissue Bank welcomes requests for tissue samples for use in research into the cause and treatment of multiple sclerosis. It has available post mortem, cryopreserved brain and spinal cord tissue both fixed and unfixed, and cerebrospinal fluid from patients with and without a history of multiple sclerosis. Freshly dissected tissue samples, or those preserved using unconventional techniques may also be made available by prior arrangement.
Proper citation: UK Multiple Sclerosis Tissue Bank (RRID:SCR_004609) Copy
Central repository of information on neuronal cell types mainly accumulating information on: Genetically labeled cell types in mouse brain and genetically engineered mouse lines for cell type research. Mouse lines are annotated with * Atlas for examining transgene expression patterns * Information on construct used to generate transgene * Associated publications * Anatomical regions where transgene is expressed (based on Atlas) * Information on where to obtain the animals Currently, the mouse lines in the database are mostly generated at Cold Spring Harbor Lab, Scripps Research Institute, Baylor College of Medicine and Brandeis University with few other exceptions. In the future, they will incorporate more mouse lines useful for neuronal cell type research. Cell types are annotated with * Anatomical region * Properties (frequently used terms in neuroscience research) * Mouse line used to define the cell type * Genome wide transcriptome data (if available) * Specific (marker) genes (if available) * Marker immunostaining data (if available) * Associated publications * Electrophysiological characterizations (when available) * Morphological characterizations (when available)
Proper citation: celltypes.org (RRID:SCR_004545) Copy
At Brain Injury Alliance of Kentucky (BIAK), a 501(c)(3) non-profit agency, our sole mission is to serve Kentucky citizens whose lives have been affected by brain injury. We do this through advocacy, education, prevention, research, service and support. BIAK links survivors of brain injury and their families to support from others with similar experience; provides them with education and information about living and coping with brain injury; assists them in locating resources for financial assistance; and seeks to connect people with sources of emotional support. BIAK began as an outgrowth of a Lexington area support group in the early 1980s. Family members, medical staff and others felt the need to expand the services and support to reach statewide. The state office was moved to Louisville and incorporated in 1986. BIAK now has offices and staff in Louisville and Lexington. BIAK seeks to share its philosophy, experience and skills with survivors, family members, students, caregivers, administrators, health professionals, legislators, the lay community and all those who desire to make a difference in the life of individuals with brain injuries and their families. At BIAK you will find information about brain injury. We define brain injury as any injury to the brain including injury received from a fall, a stroke, trauma, anoxia, infection, and tumors or other illnesses. Each year, a growing number of Kentucky citizens are affected by brain tumors. These may range from benign tumors to aggressive cancers. The Michael Quinlan Brain Tumor program recently joined BIAK to provide service and support to individuals and families who have been affected by brain tumors. There is always help available to you and your family.
Proper citation: Brain Injury Alliance of Kentucky (RRID:SCR_004764) Copy
The Pediatric Low Grade Astrocytoma (PLGA) Foundation is the largest, and only, non-profit organization dedicated to providing hope to children, parents, and families fighting Pediatric Low Grade Astrocytomas (PLGAs). We were founded in August 2007, as a 501(c)(3) foundation made up of families and friends dedicated to helping children who are struggling with brain tumors. To date, families associated with the Pediatric Low Grade Astrocytoma (PLGA) Foundation have raised over $6 million for DEDICATED PLGA research and funded over a dozen new research projects targeted specifically at children''s brain tumors or PLGA''s. These funds have supported the launch of the Dana Farber Cancer Institute''s PLGA Research Program as well as numerous grants distributed by the Brain Tumor Society, and other fine institutions. The PLGA Foundation awards 100% of funds to education and research in the search for more effective, less toxic treatment options for this potentially devastating childhood brain tumor. The PLGA Foundation actively promotes partnerships with other non-profit organizations, private individuals and government entities and has collaborated on fund raising, education and grant allocations in order to leverage resources and funds. Our goal at the Pediatric Low Grade Astrocytoma (PLGA) Foundation, also known as Fight Juvenile Pilocytic Astrocytoma (FightJPA.org), is to UNITE families around the country and around the world in the FIGHT for the lives of our children who suffer from PLGAs - childhood brain tumors. We can defeat childhood brain tumors through a united effort on all fronts to increase awareness, education, fundraising and research of pediatric low grade astrocytomas.
Proper citation: Pediatric Low Grade Astrocytoma Foundation (RRID:SCR_004758) Copy
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