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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/OrderedList.html
An R / bioconductor package for detecting similarity in ordered gene lists. Thereby, either simple lists can be compared or gene expression data can be used to deduce the lists. Significance of similarities is evaluated by shuffling lists or by resampling in microarray data, respectively.
Proper citation: OrderedList (RRID:SCR_001834) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowClust.html
A Bioconductor software package for automated gating of flow cytometry data that implements a robust model-based clustering approach based on multivariate t mixture models with the Box-Cox transformation.
Proper citation: flowClust (RRID:SCR_001807) Copy
http://www.bioconductor.org/packages/release/bioc/html/COMPASS.html
Software for combinatorial polyfunctionality analysis of single cells. It is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. It uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.
Proper citation: COMPASS (RRID:SCR_001801) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowUtils.html
Software that provides utilities for flow cytometry data.
Proper citation: flowUtils (RRID:SCR_001879) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowTrans.html
Software for profile maximum likelihood estimation of parameters for flow cytometry data transformations.
Proper citation: flowTrans (RRID:SCR_002093) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMap.html
Software package that quantifies the similarity of cell populations across multiple flow cytometry samples using a nonparametric multivariate statistical test. The algorithm allows the users to specify a reference sample for comparison or to construct a reference sample from the available data. The output of the algorithm is a set of text files where the cell population labels are replaced by a metaset of population labels, generated from the matching process.
Proper citation: flowMap (RRID:SCR_002269) Copy
https://scicrunch.org/resolver/SCR_002250
THIS RESOURCE IS NO LONGER IN SERVICE. Documented Jul 19, 2024. Metadatabase manually curated that provides web accessible tools related to genomics, transcriptomics, proteomics and metabolomics. Used as informative directory for multi-omic data analysis.
Proper citation: OMICtools (RRID:SCR_002250) Copy
https://www.bioconductor.org/packages//2.13/bioc/html/shinyTANDEM.html
Software package that provides a GUI interface for rTANDEM, an R/Bioconductor package for MS/MS protein identification. The GUI is primarily designed to visualize rTANDEM result object or result xml files. But it will also provides an interface for creating parameter objects, launching searches or performing conversions between R objects and xml files.
Proper citation: shinyTANDEM (RRID:SCR_002169) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMatch.html
Software for matching cell populations and building meta-clusters and templates from a collection of flow cytometry (FC) samples.
Proper citation: flowMatch (RRID:SCR_002283) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMeans.html
Software that identifies cell populations in Flow Cytometry data using non-parametric clustering and segmented-regression-based change point detection.
Proper citation: flowMeans (RRID:SCR_002275) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMerge.html
Software for merging of mixture components for model-based automated gating of flow cytometry data using the flowClust framework.
Proper citation: flowMerge (RRID:SCR_002224) Copy
https://bioconductor.org/packages/2.11/bioc/html/flowPhyto.html
An R package that performs aggregate statistics on virtually unlimited collections of raw flow cytometry files and provides a memory efficient, parallelized solution for analyzing high-throughput flow cytometric data.
Proper citation: flowPhyto (RRID:SCR_002183) Copy
http://www.bioconductor.org/packages/devel/bioc/html/BEAT.html
Software that implements all bioinformatics steps required for the quantitative, high-resolution analysis of DNA methylation patterns from bisulfite sequencing data.
Proper citation: BEAT (RRID:SCR_002387) Copy
http://r3cseq.genereg.net/Site/index.html
An R/Bioconductor package to identify chromosomal interaction regions generated by chromosome conformation capture (3C) coupled to next-generation sequencing (NGS), a technique termed 3C-seq. It performs data analysis for a number of different experimental designs, as it can analyze 3C-seq data with or without a control experiment and it can be used to facilitate data analysis for experiments with multiple replicates. The r3Cseq package provides functions to perform data normalization, statistical analysis for cis/trans interactions and visualization in order to help scientists identify genomic regions that physically interact with the given viewpoints of interest. This tool greatly facilitates hypothesis generation and the interpretation of experimental results.
Proper citation: r3Cseq (RRID:SCR_003198) Copy
http://www.bioconductor.org/packages/release/bioc/html/EasyqpcR.html
Software package for low-throughput real-time quantitative PCR data analysis. The package allows you to import easily qPCR data files. Thereafter, you can calculate amplification efficiencies, relative quantities and their standard errors, normalization factors based on the best reference genes choosen (using the SLqPCR package), and then the normalized relative quantities, the NRQs scaled to your control and their standard errors.
Proper citation: EasyqpcR (RRID:SCR_003406) Copy
http://www.bioconductor.org/packages/release/bioc/html/NormqPCR.html
Software package providing functions for the selection of optimal reference genes and the normalization of real-time quantitative PCR data.
Proper citation: NormqPCR (RRID:SCR_003388) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/minfi.html
Software that improves the results from the Illumina infinium HumanMethylation450 BeadChips by reducing technical variation within and between arrays. SWAN is available in the minfi Bioconductor package.
Proper citation: SWAN (RRID:SCR_003455) Copy
http://www.bioconductor.org/packages/release/bioc/html/CAMERA.html
A Bioconductor package integrating algorithms to extract compound spectra, annotate isotope and adduct peaks, and propose the accurate compound mass even in highly complex data.
Proper citation: CAMERA - Collection of annotation related methods for mass spectrometry data (RRID:SCR_002466) Copy
http://www.bioconductor.org/packages/devel/bioc/html/MethylAid.html
Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored.
Proper citation: MethylAid (RRID:SCR_002659) Copy
http://www.bioconductor.org/packages/devel/bioc/html/CGHnormaliter.html
Software for normalization and centralization of array comparative genomic hybridization (aCGH) data with imbalanced aberrations. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).
Proper citation: CGHnormaliter (RRID:SCR_002936) Copy
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