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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://cran.r-project.org/web/packages/isopat/
Software function that calculates the isotopic pattern (fine structures) for a given chemical formula.
Proper citation: Isopat (RRID:SCR_003025) Copy
http://cran.r-project.org/web/packages/ptw/
Software that aligns patterns, i.e. it aims to put corresponding features at the same locations. The algorithm searches for an optimal polynomial describing the warping. It is possible to align one sample to a reference, several samples to the same reference, or several samples to several references. One can choose between calculating individual warpings, or one global warping for a set of samples and one reference. Two optimization criteria are implemented: RMS (Root Mean Square error) and WCC (Weighted Cross Correlation).
Proper citation: Parametric Time Warping (RRID:SCR_003053) Copy
http://cran.r-project.org/web/packages/neuRosim/
Software package that allows users to generate fMRI time series or 4D data. Some high-level functions are created for fast data generation with only a few arguments and a diversity of functions to define activation and noise. For more advanced users it is possible to use the low-level functions and manipulate the arguments.
Proper citation: neuRosim (RRID:SCR_002154) Copy
https://cran.r-project.org/src/contrib/Archive/PurBayes/
An MCMC-based algorithm that uses next-generation sequencing data to estimate tumor purity and clonality for paired tumor-normal data.
Proper citation: PurBayes (RRID:SCR_002068) Copy
http://cran.r-project.org/web/packages/metaRNASeq/
Software package for meta-analysis of RNA-seq data. This package implements two p-value combination techniques (inverse normal and Fisher methods). It also provides a vignette explaining how to combine data from multiple RNA-seq experiments.
Proper citation: metaRNASeq (RRID:SCR_002174) Copy
https://cran.r-project.org/src/contrib/Archive/demi/
R package for estimating differential expression from multiple indicators that capitalizes on the high number of concurrent measurements. It extends to various experimental designs and target categories (transcripts, genes, genomic regions) as well as small sample sizes.
Proper citation: DEMI (RRID:SCR_002291) Copy
http://cran.r-project.org/src/contrib/Archive/postgwas/
A comprehensive software toolkit for post-processing, visualization and advanced analysis of GWAS results.
Proper citation: Postgwas (RRID:SCR_000156) Copy
http://cran.r-project.org/web/packages/circlize/
Software package that implements and enhances circular visualization in R. Due to natural born feature of R to draw statistical graphics, this package can provide more general and flexible way to visualize huge information in circular style.
Proper citation: circlize (RRID:SCR_002141) Copy
http://cran.r-project.org/web/packages/VennDiagram/
Software providing a set of functions to generate high-resolution Venn and Euler plots. Includes handling for several special cases, including two-case scaling, and extensive customization of plot shape and structure.
Proper citation: VennDiagram (RRID:SCR_002414) Copy
http://cran.r-project.org/web/packages/muma/
Software that provides guidelines for the whole process of metabolomic data interpretation, from data pre-processing, to dataset exploration and visualization, to identification of potentially interesting metabolites. Guidelines outline the following processes: preprocessing of high-throughput data (normalization and scalings); principal component analysis with help tool for choosing best-separating principal components and automatic testing for outliers; automatic univariate analysis for parametric and non-parametric data, with generation of specific reports (volcano and box plots); partial least square discriminant analysis (PLS-DA); orthogonal partial least square discriminant analysis (OPLS-DA); Statistical Total Correlation Spectroscopy (STOCSY); and Ratio Analysis Nuclear Magnetic Resonance (NMR) Spectroscopy (RANSY).
Proper citation: MUMA (RRID:SCR_002412) Copy
http://cran.r-project.org/web/packages/enviPick/
Software for sequential partitioning, clustering and peak detection of centroided LC-MS mass spectrometry data (.mzXML). Interactive result and raw data plot.
Proper citation: enviPick (RRID:SCR_003059) Copy
https://cran.r-project.org/src/contrib/Archive/sybil/
A Systems Biology Library for R, implementing algorithms for constraint based analyses of metabolic networks (e.g. flux-balance analysis (FBA), minimization of metabolic adjustment (MOMA), regulatory on/off minimization (ROOM), robustness analysis and flux variability analysis). This is an implementation of COBRA toolbox in R language.
Proper citation: sybil - Efficient Constrained Based Modelling in R (RRID:SCR_000457) Copy
http://www.bioconductor.org/packages/release/data/annotation/html/RmiR.Hs.miRNA.html
Software package for various databases of microRNA Targets.
Proper citation: RmiR.Hs.miRNA (RRID:SCR_000101) Copy
http://cran.r-project.org/web/packages/PSCBS/
Software R package for segmentation of allele-specific DNA copy number data and detection of regions with abnormal copy number within each parental chromosome. Both tumor-normal paired and tumor-only analyses are supported.
Proper citation: PSCBS (RRID:SCR_000417) Copy
http://cran.r-project.org/web/packages/CpGassoc/index.html
Software R package to test association between methylation at CpG sites across genome and phenotype of interest, adjusting for any relevant covariates. Can perform standard analyses of large datasets without need to manually input data. Can handle mixed effects models with chip or batch entering model as random intercept. Includes tools to apply quality control filters, perform permutation tests, and create QQ plots, manhattan plots, and scatterplots for individual CpG sites.
Proper citation: CpGassoc (RRID:SCR_000320) Copy
https://github.com/facebook/prophet
Open source software package for producing forecasts for time series data that has multiple seasonality with linear or non linear growth. Implemented in R or Phyton.
Proper citation: Prophet (RRID:SCR_017083) Copy
https://samuel-marsh.github.io/scCustomize/
Software R package for custom visualizations and functions for streamlined analyses of single cell sequencing.
Proper citation: scCustomize (RRID:SCR_024675) Copy
https://CRAN.R-project.org/package=emmeans
Software R package to obtain estimated marginal means for linear, generalized linear, and mixed models. Compute contrasts or linear functions of EMMs, trends, and comparisons of slopes. Plots and other displays.
Proper citation: emmeans (RRID:SCR_018734) Copy
https://cran.r-project.org/web/packages/factoextra/index.html
R package from CRAN to extract and visualize the results of multivariate data analysis.
Proper citation: factoextra (RRID:SCR_016692) Copy
http://jefferis.github.io/nat/
Software R package for the (3D) visualisation and analysis of biological image data, especially tracings of single neurons in the context of 3D brain structures.
Proper citation: NeuroAnatomy Toolbox (RRID:SCR_016716) Copy
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