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https://github.com/broadinstitute/pilon/

Software tool to automatically improve draft assemblies and find variation among strains, including large event detection. FASTA files of genome along with one or more BAM files of reads aligned as input. Read alignment analysis is used to identify inconsistencies between input genome and evidence in reads, then attempts to make improvements to genome.

Proper citation: Pilon (RRID:SCR_014731) Copy   

•   Source: SciCrunch Registry

https://heal.nih.gov/

Project to help to end opioid addiction. Addiction Long-term Initiative or NIH HEAL Initiative, to speed scientific solutions to stem national opioid public health crisis. Initiative is funding hundreds of projects nationwide. Researchers are taking variety of approaches to tackle opioid epidemic through understanding, managing, and treating pain, and also through improving prevention and treatment for opioid misuse and addiction.

Proper citation: NIH Heal Project (RRID:SCR_022808) Copy   

•   Source: SciCrunch Registry

http://neurosynth.org

Platform for large-scale, automated synthesis of functional magnetic resonance imaging (fMRI) data extracted from published articles. It''s a website wrapped around a set of open-source Python and JavaScript packages. Neurosynth lets you run crude but useful analyses of fMRI data on a very large scale. You can: * Interactively visualize the results of over 3,000 term-based meta-analyses * Select specific locations in the human brain and view associated terms * Browse through the nearly 10,000 studies in the database Their ultimate goal is to enable dynamic real-time analysis, so that you''ll be able to select foci, tables, or entire studies for analysis and run a full-blown meta-analysis without leaving your browser. You''ll also be able to do things like upload entirely new images and obtain probabilistic estimates of the cognitive states most likely to be associated with the image.

Proper citation: NeuroSynth (RRID:SCR_006798) Copy   

•   Source: SciCrunch Registry

http://flashx.io/

A collection of big data analytics tools. FlashX performs data analytics in the form of graphs and matrices and utilize solid-state drives (SSDs) to scale to large datasets in a single machine. It has three main components: FlashGraph, FlashMatrix, and FlashR. FlashGraph is a general-purpose programming framework with a vertex-centric programming interface for large-scale graph analysis. FlashMatrix is a matrix computation engine that provides a small set of generalized matrix operations to express varieties of data mining and machine learning algorithms. FlashR is an extension of the R programming framework to process datasets at a scale of terabytes with the speed of optimized parallel C code.

Proper citation: FlashX (RRID:SCR_014536) Copy   

•   Source: SciCrunch Registry

https://github.com/frothga/n2a

An object-oriented language for modeling large-scale neural systems, along with an IDE for writing and simulating models. N2A represents neural systems in a parts-relations framework combined with dynamics where each part has as set of equations that define its state variables and how they evolve over time. Each part is a pattern for a population of instances, and each instance has its own unique copy of the state variables.

Proper citation: N2A (RRID:SCR_014702) Copy   

•   Source: SciCrunch Registry

https://github.com/yongchao/flowPeaks

Software for fast and automatic clustering to classify the cells into subpopulations based on finding the peaks from the overall density function generated by K-means.

Proper citation: flowPeaks (RRID:SCR_000407) Copy   

•   Source: SciCrunch Registry

https://github.com/SciLifeLab/facs

Software for classification of Sequences using Bloom filters that can accurately and rapidly align sequences to a reference sequence.

Proper citation: FACS (RRID:SCR_000055) Copy   

•   Source: SciCrunch Registry

https://cran.r-project.org/web/packages/phytools/index.html

Software R package for phylogenetic comparative biology. The package contains various functions for phylogenetic analysis of comparative data from species.

Proper citation: phytools (RRID:SCR_015502) Copy   

•   Source: SciCrunch Registry

http://sun.aei.polsl.pl/gdc/

A C++ application designed for compression of genome collections from the same species.

Proper citation: GDC (RRID:SCR_001007) Copy   

•   Source: SciCrunch Registry

http://compbio.berkeley.edu/proj/juncbase/Home.html

Software used to identify and classify alternative splicing events from RNA-Seq data. JuncBASE also uses read counts to quantify the relative expression of each isoform and identifies splice events that are significantly differentially expressed across two or more samples.

Proper citation: JuncBASE (RRID:SCR_003103) Copy   

•   Source: SciCrunch Registry

http://deweylab.biostat.wisc.edu/rsem/

Software package for quantifying gene and isoform abundances from single end or paired end RNA Seq data. Accurate transcript quantification from RNA Seq data with or without reference genome. Used for accurate quantification of gene and isoform expression from RNA-Seq data.

Proper citation: RSEM (RRID:SCR_000262) Copy   

•   Source: SciCrunch Registry

https://github.com/princelab/mspire-simulator

A free, open-source shotgun proteomic simulator that goes beyond previous simulation attempts by generating LC-MS features with realistic m/z and intensity variance along with other noise components.

Proper citation: Mspire-Simulator (RRID:SCR_001431) Copy   

•   Source: SciCrunch Registry

http://www.re3data.org/

Global registry of research data repositories from all academic disciplines that allows the easy identification of appropriate research data repositories, both for data producers and users. Information icons display principal attributes of a repository that can be used for multi-faceted searches. Repository operators can suggest their infrastructures to be listed via a simple application form. A repository is indexed when the minimum requirements are met, i.e. mode of access to the data and repository, as well as the terms of use.

Proper citation: re3data.org (RRID:SCR_006782) Copy   

•   Source: SciCrunch Registry

http://www.evoio.org/wiki/MIAPA

Central hub for resources related to developing and deploying a Minimal Information for a Phylogenetic Analysis (MIAPA) standard.

Proper citation: MIAPA (RRID:SCR_003777) Copy   

•   Source: SciCrunch Registry

http://cbcb.umd.edu/software/metAMOS

A modular and open source metagenomic assembly and analysis pipeline.

Proper citation: MetAMOS (RRID:SCR_011914) Copy   

•   Source: SciCrunch Registry

https://pythonhosted.org/eelbrain/

Statistical analysis toolbox for MEG and EEG. There are three primary data-objects: Factor for categorical variables, Var for scalar variables, and NDVar for multidimensional data. Factor is a container for one-dimensional, categorial data – each case is described by a string label. Var is a container to associate one-dimensional numpy.ndarray objects with a name. NDVars offer numpy functionality that takes into account the dimensions. There is also a Dataset class which acts as a vessel for variable objects (Factor, Var and NDVar) describing the same cases.

Proper citation: Eelbrain (RRID:SCR_014661) Copy   

•   Source: SciCrunch Registry

https://github.com/marcel-goldschen-ohm/SingleMoleculeImageAnalysis

MATLAB software tool collection for data acquisition and image analysis from zero mode waveguides.

Proper citation: Zero Mode Waveguide Imaging and Analysis package tools (RRID:SCR_014660) Copy   

•   Source: SciCrunch Registry

http://cole-trapnell-lab.github.io/cufflinks/cuffmerge/

Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality.

Proper citation: Cufflinks (RRID:SCR_014597) Copy   

•   Source: SciCrunch Registry

http://visionegg.org/

A programming library that uses standard graphics cards to produce 2D and 3D visual stimuli for vision research experiments.

Proper citation: Vision Egg (RRID:SCR_014589) Copy   

•   Source: SciCrunch Registry

https://github.com/galaxyproject/bioblend

A Python library which provides Python access to and interaction with Galaxy's API and CloudMan. The library allows users to create a CloudMan compute cluster via an API and directly from a local machine, reconnect to an existing CloudMan instance and manipulate it, and interact with Galaxy via a straightforward API and an object-oriented API. The library itself can be used with either service irrespective of the other.

Proper citation: BioBlend Library (RRID:SCR_014557) Copy   

•   Source: SciCrunch Registry