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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://harvard.eagle-i.net/i/0000012e-3517-ac53-550e-f59280000000
Core facility that provides metals analytical capabilities to biomedical and non-biomedical researchers and serves as a source for study design consultation and sample QA/QC requirements. The transport, fate, exposure, and toxic effects of heavy metals is a primary focus of research at the Center. It operates as a modified fee-for-service laboratory. Researchers have the option of having the samples run by the Service staff, or of receiving instruction (for themselves or a doctoral or post doctoral trainee) on how to operate the analytical equipment and analyze their own samples. Both options have associated fees and, as with other services, facility access funds can be requested internal or external services when individual grant support is not yet available.
Proper citation: HSPH Trace Metals Laboratory (RRID:SCR_002819) Copy
http://harvard.eagle-i.net/i/00000137-e19e-59a0-d807-77a880000000
Microscopists at Weld Hill will find a range of tools from the simple hand lens to the confocal microscope for 3-D reconstructions.
Proper citation: Arnold Arboretum of Harvard University: Weld Hill Microscopy Lab (RRID:SCR_004485) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-c61a-a13e-b341-4bb480000000
Core facility that provides the following services: Energy Expenditure Assessment, Body Composition Assessment, Physical Activity Assessment. This component of the core utilizes existing institutional resources for measurement of energy balance and provides personnel support that permit assessment of research in energy balance and nutrition assessment.
Proper citation: Vanderbilt Energy Balance Core Laboratory (RRID:SCR_006665) Copy
http://dartmouth.eagle-i.net/i/0000012a-24fd-6cc0-d8a1-249280000000
Core facility that provides the following services: 7500 fast Q-PCR service, MALDI MS service, Agilent 2100 bioanalyzer service, NanoDrop 1000 service.
Proper citation: Dartmouth Shared Instruments Core Laboratory (RRID:SCR_006415) Copy
http://harvard.eagle-i.net/i/0000012c-60c2-395c-c437-ff0b80000000
Core facility that provides the following services: Cell immortalization through retroviral or lentiviral vectors service, Microscopy training, User-based microscopy service.
Proper citation: BWH Cell Culture and Microscopy Core (RRID:SCR_005562) Copy
https://www.ohsu.edu/transgenic-mouse-models-core
Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.
Proper citation: OHSU Animal Model Support Core Facility (RRID:SCR_009994) Copy
http://www.scienceexchange.com/facilities/specimen-bank-bwh-harvard
Core facility that provides the following services: Open repositories service, Sample processing service, Medical/pathology informatics support service, BWH tissue repository service.
The Specimen Bank provides materials to investigators with IRB-approved protocols. Staff are available to assist with selection of samples appropriate for downstream applications, development of processing protocols or preparation of derivatives from clinical materials. IT Staff are also available to assist researchers with creation of queries for prospective sample collection or queries to select samples from specific cohorts. Their goal is to drive quality research in an efficient and cost-effective manner. Each year they provide tens of thousands of samples to area researchers. Getting started: Partners investigators and study staff may request a Crimson user account to help manage studies and collected materials.
Proper citation: BWH Specimen Bank (RRID:SCR_012316) Copy
http://www.scienceexchange.com/facilities/microarray-and-bioinformatics-core-mmc
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Core facility that provides the following services: RNA quality analysis service, qRT-PCR service, Microarray service, Bioinformatics data analysis service. The Core provides state of the art training, instrumentation, services and bioinformatics-driven data analysis to the Meharry Community in microarray experimental design, manipulation, and gene expression analysis. They also aid investigators and trainees in validation of microarray results using RNA QA/QC and real time PCR results. Finally, this Core Resource aids Meharry investigators and trainees with high performance computation in proteomics as well as genomics. Gene and protein pathways analysis and shotgun proteomics (mass spectrometry) analysis are just two more of the services that we provide. It is their aim to keep this facility up to date computationally and intellectually with state of the art Omics services to support education and research in microarray, genomics and proteomics data analysis, computational biology, and systems biology.
Proper citation: Meharry Microarray and Bioinformatics Core (RRID:SCR_012229) Copy
Core facility that provides the following services: Positron emission tomography service.
The Martinos Center''''s dual mission includes translational research and technology development. The core technologies being developed and used at the center are magnetic resonance imaging (MRI) and spectroscopy (MRS), magnetoencephalography (MEG) and electroencephalograpy (EEG), near infra-red spectroscopy (NIRS) and diffuse optical tomography (DOT), Positron Emission Tomography (PET), electrophysiology, molecular imaging, and computational image analysis. A particular area of innovation at the Center is Multimodal Functional Neuroimaging which involves the integration of imaging technologies. They are also world leaders in the development of primate neuroimaging techniques. Major areas of research at the center include, psychiatric, neurologic and neurovascular disorders, basic and cognitive neuroscience, cardiovascular disease, cancer and more. With an extensive and expanding inventory of state-of-the-art imaging facilities, a world class team of investigators and collaborators, and important government, industry and private supporters, the Martinos Center is leading the way to new advances and applications in biomedical imaging.
Proper citation: MGH Martinos Center for Biomedical Imaging Core Facility (RRID:SCR_012324) Copy
https://www.joslin.org/islet-isolation-core.html
Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.
Proper citation: Joslin Diabetes Center Islet Isolation Core (RRID:SCR_012299) Copy
http://www.schepens.harvard.edu/graphics
Core facility that provides the following services: Web and graphic services, Web design and content management service, Photography service. Peter Mallen is a designer and illustrator who manages a full-service web and graphics studio in a moderately sized scientific research facility, Schepens Eye Research Institute. He provides a full range of graphic design, scientific illustration, web design and development, content management, and general design and production services. His products are utilized by: faculty and scientific staff (books, scientific publications, slide shows, grant applications); professional staff (Administration, Development & Public Affairs; brochures, books, pamphlets); the general public (Institute websites) as well as clients of our 250-seat state-of-the-art conference center, Starr Center for Scientific Communications.
Proper citation: Harvard SERI Graphic Services Core (RRID:SCR_012309) Copy
http://www.massgeneral.org/psychiatry/research/pngu_home.aspx
Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.
Proper citation: MGH Psychiatric and Neurodevelopmental Genetics Unit Core Lab (RRID:SCR_012301) Copy
http://www.neurodiscovery.harvard.edu/resources/atrc.html
Core facility that provides provides state-of-the-art molecular pathology resources to the Harvard community including laser capture microscopy, DNA/RNA/miRNA quality/expression analysis, Luminex FlexMap 3D multiplex bead cytometry, and real-time PCR. The ATRC is a fee-for-use facility. For NeuroDiscovery members, the first 10 hours of training, consultation and instrument use is free. This initial period is intended to provide a first time user with preliminary data/proof of concept regarding their project, and is generally sufficient when investigators work under the aegis of ATRC staff. Thereafter, the base fee varies depending on activity and the extent of your proposed work. Project-based charge-back agreements for large projects can be negotiated with the ATRC Director, Dr. Charles Vanderburg. Although priority is given to NeuroDiscovery members investigating neurodegenerative diseases and the CNS, the facility is also available to any academic investigators within the Harvard medical community and the greater-Boston research community. Under special arrangements the facility may also be made available to the commercial sector. Please contact ATRC Director, Dr. Charles Vanderburg, for details.
Proper citation: HNDC Advanced Tissue Resource Center (RRID:SCR_012670) Copy
http://bioinformatics.hms.harvard.edu/
Core facility that offers consultations on basic questions in research computing, bioinformatics and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise. Core has experience in large-scale data management, database design and software development. Staff members can provide assistance in quality assurance and analysis of gene expression arrays, genome-wide SNP arrays, CNV studies and different aspects of second-generation sequencing technologies such as ChIP-seq, RNA-Seq or resequencing efforts. Services also include provision of external information generated from public database, data curation and assistance on choosing the right data format and annotation standard to ensure best practices in data management and submission are being maintained.
Proper citation: Harvard Chan Bioinformatics Core (RRID:SCR_012655) Copy
http://flowcytometry.sysbio.med.harvard.edu/
Core facility that provides the following services: Sorting and analysis services. The facility houses two state-of-the-art BD analyzers with high-throughput capability, a Stratedigm benchtop analyzer, a high-speed BD cell sorter, and both Mac and PC workstations for data analysis. Sorting services are offered through the facility, as well as instrument and software training.
Proper citation: HMS Systems Biology Flow Cytometry Facility (RRID:SCR_012696) Copy
http://ohsu.eagle-i.net/i/0000012a-24ff-653a-d994-629180000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Confocal and epi-fluorescence imaging, Image processing and analysis, Stereology measurement service, Laser Capture Microdissection service, Live cell imaging service. The Imaging and Morphology Support Core of the ONPRC is designed to meet the imaging needs of ONPRC scientists and of the OHSU scientific community by providing state-of-the-art facilities, expertise, assistance and training in the use of advanced light microscopy, image analysis, processing and printing, and laser capture microdissection. Special emphasis is placed on quantitative evaluation of imaging experiments using both stereology and automated image analysis.
Proper citation: OHSU Imaging and Morphology Support Core Laboratory (RRID:SCR_009978) Copy
http://ohsu.eagle-i.net/i/0000012b-00cb-8534-79a3-373680000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Sterols assay, Mevalonic acid assay. The OHSU Lipid Lab offers precise determination of lipids and specialized lipid metabolites not routinely available in general hospital clinical labs or elsewhere in Oregon. Currently, the OHSU Lipid Lab is the only laboratory on the West Coast that does sterols.
Proper citation: OHSU Lipid-Atherosclerosis Laboratory (RRID:SCR_009976) Copy
http://ohsu.eagle-i.net/i/0000012b-00c9-392d-79a3-373680000000
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6, 2022.Core facility that provides the following services: 17-hydroxyprogesterone (17a-P)-RIA, Androstenedioine (A4)-Ext-Chrom-RIA, b-Endorphin (bEP)-Iodination-RIA, Cholecystokinin (CCK)-Iodination-RIA, Corticosterone-Ext-RIA, Corticotropin-releasing factor (CRF)-Iodination-RIA, Dehydrocorticosterone (DOC)-Ext-RIA, Dihydrotestosterone (DHT)-Ext-Chrom-RIA, Estradiol-17b (E2)-Ext-RIA, Estradiol-17b (E2)-Ext-Chrom-RIA, Follicle-stimulating hormone (FSH)-Iodination-RIA, Gonadotropin-releasing hormone (GnRH)-Iodination-RIA, Growth hormone-releasing hormone (GHRH)-Iodination-RIA, Luteinizing hormone (LH)-Iodination-RIA, Neuropeptide Y (NPY)-Iodination-RIA, Progesterone (P4)-Ext-RIA, Progesterone (P4)-Ext-Chrom-RIA, 17-hydroxyprogesterone (17a-P)-Ext-Chrom-RIA, Testosterone (T)-Ext-RIA, Testosterone (T)-Ext-Chrom-RIA, Aldosterone-Active-RIA, Androstenedioine (A4)-CTC-RIA, Androstenedioine (A4)-Double-Antibody RIA, Corticosterone-RIA, Cortisol (17a-hydroxycorticosterone)-RIA, Cortisol (17a-hydroxycorticosterone)-ELISA, Dehydroepiandrosterone (DHEA)-ELISA, Dehydroepiandrosterone (DHEA)-RIA, Dexamethasone-ELISA, Dihydrotestosterone (DHT)-RIA, Estradiol-17b (E2)-Double-Antibody RIA, Estradiol-17b (E2)-Ultra-sensitive RIA, Estradiol-17b (E2)-Coat-the-Count RIA, Estradiol-17b (E2)-ELISA, Estrone (E1)-ELISA, Estrone (E1)-RIA, Free Testosterone (Free T)-Coat-the-count RIA, Free Testosteroine (Free T)-RIA, Glucagon-RIA, Insulin-RIA, Insulin-ELISA, Insulin (human)-RIA, Insulin (rat)-RIA, Insulin (sensitive rat)-RIA, Pregnenolone-EIA, Progesterone (P4)-RIA, Progesterone (P4) (17alpha-OH)-ELISA, Progesterone (P4)-EIA, Testosterone (T)-RIA, Testosterone (T)-EIA, Testosterone (T)-ELISA, Adiponectin (Rat)-ELISA, Adrenocorticotropins (ACTH)-RIA, Anti-Mullerian hormone-Active-ELISA, C-Peptide-RIA, Cotinine-ELISA, Cotinine (rat)-ELISA, C-reactive protein (CRP)-Ultra-sensitive ELISA, Cytokines, individual-ELISA, Dehydroepiandrosterone sulfate (DHEAS)-RIA, Delta-like 1 (DLK-1)-ELISA, Ethinyl estradiol (EE2)-Ext-RIA, Follicle-stimulating hormone (FSH)-RIA, Ghrelin (human)-RIA, Growth hormone (GH)-ELISA, Growth hormone (GH) (rat)-RIA, 5-Hydroxyindoleacetic acid (5-HIAA)-ELISA, Inhibin-a-ELISA, Inhibin-b-Active-ELISA, Insulin-like growth factor (IGF-1)-ELISA, Insulin-like growth factor (IGF-1) (mouse/rat)-ELISA, Leptin (mouse)-RIA, Leptin (primate)-RIA, Leptin (rat)-RIA, Levonorgestrel (LNG)-Ext-RIA, Low-density Lipoprotein (LDL)-EIA, Prolactin (rat)-ELISA, Prostate-specific antigen (PSA)-ELISA, Quantikine HS-High sensitivity ELISA, Serotonin (5-HT)-RIA, Serotonin (5-HT)-ELISA, Vasopressin-EIA-Extraction. The Endocrine Technology Support Core Lab (ETSL) has provided intra- and extramural investigators with analysis of protein and steroid content in blood, as well as in biological tissues and fluids for more than 3 decades. Principal support functions include provision of routine assays (for most naturally occurring steroid and protein hormones involved in the regulation of reproduction, metabolism, and the central nervous system) and development of new assays (e.g., Multiplex platforms for cytokines and signaling molecules).
Proper citation: OHSU Endocrine Technology Support Core Laboratory (RRID:SCR_009973) Copy
http://ohsu.eagle-i.net/i/0000012a-2500-0a1a-d994-629180000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Equipment design and fabrication service, Computer interfacing service, Embedded processor design service, Circuit board design service, Research equipment consulting. The Electronics & Instrument Design Core Resource provides hands-on design and fabrication of specialized equipment for research projects. Projects involve analog and digital electronics design, microcontroller, software development and optical and embedded processor design. The core director, John Hunt, MSEE, is a senior research engineer and instructor in the Department of Biomedical Engineering, OHSU School of Medicine. OHSU School of Medicine. He has worked as a research engineer at OGI/OHSU since 1980 and has developed equipment for many research projects and departments.
Proper citation: OHSU Electronics and Instrumentation Design Core Resource (RRID:SCR_009971) Copy
http://upr.eagle-i.net/i/0000012b-00bf-e710-9e37-5ded80000000
These facilities contain three examination/study rooms, two gynecological examination rooms, two infusion rooms, one dental room, and one record room.
Proper citation: Puerto Rico Clinical and Translational Research Consortium Nursing Services (RRID:SCR_009970) Copy
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