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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Cancer Genome Anatomy Project
 
Resource Report
Resource Website
100+ mentions
Cancer Genome Anatomy Project (RRID:SCR_003072) CGAP data or information resource, portal, topical portal Project to determine the gene expression profiles of normal, precancer, and cancer cells, whose generated resources are available to the cancer community. Interconnected modules provide access to all CGAP data, bioinformatic analysis tools, and biological resources allowing the user to find in silico answers to biological questions in a fraction of the time it once took in the laboratory. * Genes * Tissues * Pathways * RNAi * Chromosomes * SAGE Genie * Tools gene, gene expression, normal cell, precancer cell, cancer cell, cell, genome, anatomy, gene expression profile, tissue, pathway, rnai, chromosome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: National Cancer Institute
is parent organization of: CGAP GO Browser
Cancer, Normal, Precancer NCI Free, download Freely available biotools:cgap, nif-0000-30468 https://mitelmandatabase.isb-cgc.org/mb_search SCR_003072 Cancer Genome Anatomy Project (CGAP) 2026-08-29 11:21:41 108
Primer3Plus
 
Resource Report
Resource Website
1000+ mentions
Primer3Plus (RRID:SCR_003081) Primer3Plus analysis service resource, data analysis service, production service resource, service resource, software resource, source code A web interface to the Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3. primer, dna sequence, primer design, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Primer3
has parent organization: Wageningen University and Research Centre; Gelderland; Netherlands
Howard Hughes Medical Institute ;
NHGRI R01-HG00257;
NHGRI P50-HG00098
PMID:17485472 Free, Freely available biotools:primer3plus, OMICS_02347 https://bio.tools/primer3plus SCR_003081 Primer3Plus - pick primers from a DNA sequence 2026-08-29 11:21:42 1860
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-08-29 11:21:24 4
BRAIN
 
Resource Report
Resource Website
10+ mentions
BRAIN (RRID:SCR_003018) software resource Software package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23350948 GNU General Public License, v2 biotools:brain, OMICS_02410 https://bio.tools/brain SCR_003018 Baffling Recursive Algorithm for Isotopic distributioN calculations, Baffling Recursive Algorithm for Isotope distributioN 2026-08-29 11:21:19 47
DIALIGN
 
Resource Report
Resource Website
10+ mentions
DIALIGN (RRID:SCR_003041) DIALIGN analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Tool for multiple sequence alignment using various sources of external information that is particularly useful to detect local homologies in sequences with low overall similarity. While standard alignment methods rely on comparing single residues and imposing gap penalties, DIALIGN constructs pairwise and multiple alignments by comparing entire segments of the sequences. No gap penalty is used. This approach can be used for both global and local alignment, but it is particularly successful in situations where sequences share only local homologies. Several versions of DIALIGN are available online at GOBICS, http://dialign.gobics.de/ dna, protein, sequence alignment, sequence, alignment, fasta, genome, genomic sequence, homology, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Bielefeld University; North Rhine-Westphalia; Germany
PMID:15215344
PMID:23620293
DOI:10.1186/1748-7188-3-6
Free, Available for download, Freely available nif-0000-30417, OMICS_24606, OMICS_00973, biotools:dialign-tx http://dialign.gobics.de/, https://bio.tools/dialign-tx https://sources.debian.org/src/dialign-tx/ SCR_003041 DIALIGN at GOBICS 2026-08-29 11:21:40 44
FlipFlop
 
Resource Report
Resource Website
FlipFlop (RRID:SCR_000625) software resource Software that discovers which isoforms of a gene are expressed in a given sample together with their abundances, based on RNA-Seq read data. standalone software, unix/linux, mac os x, windows, r, rna-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24813214 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04028, biotools:flipflop https://bio.tools/flipflop SCR_000625 flipflop - Fast lasso-based isoform prediction as a flow problem 2026-08-29 11:20:33 0
BLASR
 
Resource Report
Resource Website
10+ mentions
Discontinued
BLASR (RRID:SCR_000764) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. C++ long-read aligner for PacBio reads., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Proovread
PMID:22988817
DOI:10.1186/1471-2105-13-23
THIS RESOURCE IS NO LONGER IN SERVICE biotools:blasr, OMICS_05134 https://bio.tools/blasr, https://sources.debian.org/src/blasr/ SCR_000764 Basic Local Alignment with Successive Refinement, BLASR: The PacBio long read aligner 2026-08-29 11:20:47 15
GMcloser
 
Resource Report
Resource Website
1+ mentions
GMcloser (RRID:SCR_000646) GMcloser software resource Software that fills and closes the gaps present in scaffold assemblies, especially those generated by the de novo assembly of whole genomes with next-generation sequencing (NGS) reads. Unlike other gap-closing tools that use only NGS reads, GMcloser uses preassembled contig sets or long read sets as the sequences to close gaps and uses paired-end (PE) reads and a likelihood-based algorithm to improve the accuracy and efficiency of gap closure. The efficiency of gap closure can be increased by successive treatments with different contig sets. scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:26261222 Free, Available for download, Freely available biotools:gmcloser, OMICS_00042 https://bio.tools/gmcloser SCR_000646 Gmcloser - Closing the gaps in scaffolds with preassembled contigs 2026-08-29 11:20:33 3
clipcrop
 
Resource Report
Resource Website
clipcrop (RRID:SCR_000678) software resource Software tool for detecting structural variations with single-base resolution using soft-clipping information from SAM files. structural variation, detecting structural variations, soft-clipping information, SAM files, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22373054 Free, Available for download, Freely available biotools:clipcrop, OMICS_00310 https://bio.tools/clipcrop SCR_000678 ClipCrop 2026-08-29 11:20:34 0
TriageTools
 
Resource Report
Resource Website
TriageTools (RRID:SCR_000675) TriageTools software resource A collection of tools for partitioning raw data (fastq reads) from high-throughput sequencing projects. The tools are designed for basic data management as well for prioritizing analysis of certain subsets. matlab, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23408855 Free, Available for download, Freely available biotools:triagetools, nlx_156740 https://bio.tools/triagetools SCR_000675 2026-08-29 11:20:45 0
Opera
 
Resource Report
Resource Website
1+ mentions
Opera (RRID:SCR_000665) software resource A sequence assembly software program that uses information from paired-end reads to optimally order and orient contigs assembled from shotgun-sequencing reads. sequence assembly, paired-end, orient contigs, shotgun-sequencing, shotgun, software program, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:27169502
PMID:21929371
Free, Available for download, Freely available biotools:opera, OMICS_00045 https://bio.tools/opera SCR_000665 OPERA-LG, Optimal Paired-End Read Assembler 2026-08-29 11:20:29 3
bsseq
 
Resource Report
Resource Website
1+ mentions
bsseq (RRID:SCR_001072) data analysis software, data processing software, sequence analysis software, software application, software resource R package with tools for analyzing and visualizing bisulfite sequencing data. bisulfite sequencing, analyze, r, sequence analysis software, data analysis software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01847, biotools:bsseq https://bio.tools/bsseq SCR_001072 bsseq - Analyze manage and store bisulfite sequencing data 2026-08-29 11:20:58 8
SplitSeek
 
Resource Report
Resource Website
1+ mentions
SplitSeek (RRID:SCR_001012) data analysis software, data processing software, sequence analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented September 20, 2016. A program for de novo prediction of splice junctions in RNA-seq data. bioinformatics alignment, sequence analysis software, de novo, prediction, rna seq, rna, splice junction, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20236510 THIS RESOURCE IS NO LONGER IN SERVICE biotools:splitseek, OMICS_01253 https://bio.tools/splitseek http://www.uppmax.uu.se/software/splitseek SCR_001012 2026-08-29 11:20:56 1
ASC
 
Resource Report
Resource Website
1+ mentions
ASC (RRID:SCR_001013) ASC software resource Borrows information across sequences to establish prior distribution of sample variation, so that biological variation can be accounted for even when replicates are not available. sample variation, rna, dna, biology, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Brown University; Rhode Island; USA
biotools:sqn, OMICS_01298 https://bio.tools/sqn SCR_001013 2026-08-29 11:20:34 1
AutoAssemblyD
 
Resource Report
Resource Website
AutoAssemblyD (RRID:SCR_001087) data analysis software, data processing software, sequence analysis software, software application, software resource Software which performs local and remote genome assembly by several assemblers based on an XML Template which can replace the large command lines required by most assemblers. genome, genome assembly, xml, sequence analysis software, local genome assembly, remote genome assembly, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24143057 Free, Available for download, Freely available biotools:autoassemblyd, OMICS_00874 https://bio.tools/autoassemblyd SCR_001087 2026-08-29 11:20:42 0
jmzML
 
Resource Report
Resource Website
1+ mentions
jmzML (RRID:SCR_001119) software resource A Java application programming interface (API) for the Proteomics Standards Initiative mzML data standard. standalone software, mac os x, unix/linux, windows, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:20127693 Free, Available for download, Freely available biotools:jmzml, OMICS_03340 https://bio.tools/jmzml SCR_001119 2026-08-29 11:20:59 1
massiR
 
Resource Report
Resource Website
massiR (RRID:SCR_001157) software resource Software that predicts the sex of samples in gene expression microarray datasets. standalone software, mac os x, unix/linux, windows, r, classification, clustering, gene expression, microarray, quality control, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24659105 Free, Available for download, Freely available biotools:massir, OMICS_03638 https://bio.tools/massir SCR_001157 massiR: MicroArray Sample Sex Identifier, MicroArray Sample Sex Identifier 2026-08-29 11:20:44 0
Reaper - Demultiplexing trimming and filtering sequencing data
 
Resource Report
Resource Website
1+ mentions
Reaper - Demultiplexing trimming and filtering sequencing data (RRID:SCR_001144) Reaper software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23, 2022. Software program for demultiplexing, trimming and filtering short read sequencing data. c, alignment, sequence, demultiplex, trim, filter, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: European Bioinformatics Institute
THIS RESOURCE IS NO LONGER IN SERVICE biotools:reaper, OMICS_02157 https://bio.tools/reaper SCR_001144 2026-08-29 11:20:44 1
Skylign
 
Resource Report
Resource Website
10+ mentions
Skylign (RRID:SCR_001176) Skylign analysis service resource, data analysis service, production service resource, service resource, software resource A tool for creating logos representing both sequence alignments and profile hidden Markov models. The interactive logos enable scrolling, zooming, and inspection of underlying values. Skylign can avoid sampling bias in sequence alignments by down-weighting redundant sequences and by combining observed counts with informed priors. It also simplifies the representation of gap parameters, and can optionally scale letter heights based on alternate calculations of the conservation of a position. sequence alignment, profile, logo, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Janelia Research
PMID:24410852 Creative Commons Attribution License, v3 Unported biotools:skylign, OMICS_02182 https://bio.tools/skylign SCR_001176 Skylign - Interactive logos for alignments and profile HMMs 2026-08-29 11:20:37 13
yaqcaffy
 
Resource Report
Resource Website
1+ mentions
yaqcaffy (RRID:SCR_001295) yaqcaffy software resource Software package for quality control of Affymetrix GeneChip expression data and reproducibility analysis of human whole genome chips with the MAQC reference datasets. microarray, one channel, quality control, report writing, affymetrix, gene expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available BioTools:yaqcaffy, biotools:yaqcaffy, OMICS_02040 http://www.bioconductor.org/packages/release/bioc/html/yaqcaffy.html SCR_001295 yaqcaffy - Affymetrix expression data quality control and reproducibility analysis 2026-08-29 11:21:01 3

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