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Ontology to describe and categorize chemical biology and drug screening assays and their results including high-throughput screening (HTS) data for the purpose of categorizing assays and data analysis. BAO is an extensible, knowledge-based, highly expressive (currently SHOIQ(D)) description of biological assays making use of descriptive logic based features of the Web Ontology Language (OWL). BAO currently has over 700 classes and also makes use of several other ontologies. It describes several concepts related to biological screening, including Perturbagen, Format, Meta Target, Design, Detection Technology, and Endpoint. Perturbagens are perturbing agents that are screened in an assay; they are mostly small molecules. Assay Meta Target describes what is known about the biological system and / or its components interrogated in the assay (and influenced by the Perturbagen). Meta target can be directly described as a molecular entity (e.g. a purified protein or a protein complex), or indirectly by a biological process or event (e.g. phosphorylation). Format describes the biological or chemical features common to each test condition in the assay and includes biochemical, cell-based, organism-based, and variations thereof. The assay Design describes the assay methodology and implementation of how the perturbation of the biological system is translated into a detectable signal. Detection Technology relates to the physical method and technical details to detect and record a signal. Endpoints are the final HTS results as they are usually published (such as IC50, percent inhibition, etc). BAO has been designed to accommodate multiplexed assays. All main BAO components include multiple levels of sub-categories and specification classes, which are linked via object property relationships forming an expressive knowledge-based representation.
Proper citation: Bioassay Ontology (RRID:SCR_002638) Copy
Computable knowledge regarding functions of genes and gene products. GO resources include biomedical ontologies that cover molecular domains of all life forms as well as extensive compilations of gene product annotations to these ontologies that provide largely species-neutral, comprehensive statements about what gene products do. Used to standardize representation of gene and gene product attributes across species and databases.
Proper citation: Gene Ontology (RRID:SCR_002811) Copy
http://purl.bioontology.org/ontology/WB-PHENOTYPE
A structured controlled vocabulary of Caenorhabditis elegans phenotypes.
Proper citation: C. elegans Phenotype Vocabulary (RRID:SCR_006924) Copy
http://purl.bioontology.org/ontology/CCON
Ontology of Cerrado wood plant dynamics to represent the set of concepts about the dynamics, that is, changes over time of the wood vegetation structure, of Cerrado. Ccon describes the main parameters used to measure the changes, such as mortality rate and recruitment rate.
Proper citation: Cerrado concepts and plant community dynamics (RRID:SCR_007174) Copy
http://purl.bioontology.org/ontology/EP
Ontology that contains terms describing single-channel electrophysiological experiments and data obtained using voltage-clamp, current clamp and fluorescence imaging techniques applied at the cell level and multi-channel fluorescence imaging techniques applied at the cell, tissue and whole heart levels.
Proper citation: Cardiac Electrophysiology Ontology (RRID:SCR_007065) Copy
http://purl.bioontology.org/ontology/GRO-CPGA
A structured controlled vocabulary for the anatomy of Gramineae. Please note that this ontology has now been superseded by the Plant Ontology, http://bioportal.bioontology.org/ontologies/1587.
Proper citation: Cereal Plant Gross Anatomy Ontology (RRID:SCR_007061) Copy
http://purl.bioontology.org/ontology/CCONT
ontology for the formal representation of cell lines and their correspnding culture conditions.
Proper citation: Cell Culture Ontology (RRID:SCR_007096) Copy
http://fireball.drexelmed.edu/birnlex/OWLdocs/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on April 26, 2011. Lexicon that provides entities for data and database annotation for the BIRN project, covering anatomy, disease, data collection, project management and experimental design. These sources may include complex image databases, such as data from structural and functional magnetic resonance imaging (MRI) on human subjects involved in studies on Alzheimer''s disease or schizophrenia. The BIRNLex is a specialized vocabulary utilized by BIRN scientists in the context of their research, including common terms for neuroanatomy, molecular species, subject information, behavioral and cognitive processes, experimental practice and design, and the associated elements of primary data provenance required for large-scale data integration across disparate experimental studies.The BIRNLex offers well defined terms from several domains of importance to neuroimaging across scales.
Proper citation: BIRNLex (RRID:SCR_007326) Copy
http://purl.bioontology.org/ontology/CNO
A controlled vocabulary of terms used in Computational Neurosciences to describe models of the nervous system. This first release of CNO is an alpha version and should be further aligned with other ontologies accessible on Bioportal and should be made compliant with the OBO foundry recommendations.
Proper citation: Computational Neuroscience Ontology (RRID:SCR_007289) Copy
http://purl.bioontology.org/ontology/SPTO
Ontology for Solanaceae crop phenotypes and traits, developed in collaboration with the research community, especially for breeder traits of agronomic importance.
Proper citation: Solanaceae Phenotype Ontology (RRID:SCR_007832) Copy
http://purl.bioontology.org/ontology/CPRO
A uniform core set of data elements (whose formal semantics are captured in OWL) for use in a Computer-Based Patient Record (CPR)
Proper citation: Computer-Based Patient Record Ontology (RRID:SCR_007540) Copy
http://purl.bioontology.org/ontology/SOY
Growth, trait and development ontology for soybean
Proper citation: Soy Ontology (RRID:SCR_007847) Copy
http://purl.bioontology.org/ontology/HCPCS
Ontology for the healthcare common procedure coding system.
Proper citation: Healthcare Common Procedure Coding System (RRID:SCR_007598) Copy
http://purl.bioontology.org/ontology/DIKB
An evidence taxonomy for pharmacologic studies that, when combined with a set of inclusion criteria, enable drug experts to specify what their confidence in a drug mechanism assertion would be if it were supported by a specific set of evidence.
Proper citation: Drug Interaction Knowledge Base Ontology (RRID:SCR_007591) Copy
http://purl.bioontology.org/ontology/CHD
An ontology that describes the Congenital Heart Defects data.
Proper citation: Congenital Heart Defects Ontology (RRID:SCR_007584) Copy
http://purl.bioontology.org/ontology/SSE
Memorial Sloan-Kettering Cancer Center''s ontology of surgical secondary events (adverse events).
Proper citation: Surgical Secondary Events (RRID:SCR_007894) Copy
http://purl.bioontology.org/ontology/JERM
An ontology to describe the entities and relationships in the SEEK database, a Systems Biology environment for the sharing and exchange of data and models. The SysMO-SEEK database contains the work of the SysMO consortium (Systems Biology of Micro-Organisms) https://seek.sysmo-db.org/
Proper citation: SysMO JERM Ontology of Systems Biology for Micro-Organisms (RRID:SCR_004569) Copy
http://www.proconsortium.org/pro/
An ontological representation of protein-related entities by explicitly defining them and showing the relationships between them. Each PRO term represents a distinct class of entities (including specific modified forms, orthologous isoforms, and protein complexes) ranging from the taxon-neutral to the taxon-specific. The ontology has a meta-structure encompassing three areas: proteins based on evolutionary relatedness (ProEvo); protein forms produced from a given gene locus (ProForm); and protein-containing complexes (ProComp). NOTICE: The PRO ID format has changed from PRO: to PR: (e.g. PRO:000000563 is now PR:000000563).
Proper citation: PR (RRID:SCR_004964) Copy
http://purl.bioontology.org/ontology/GRO-CPD
A structured controlled vocabulary for describing cereal plant development and growth stages. Please note that this ontology has now been superseded by the Plant Ontology.
Proper citation: Cereal Plant Development Ontology (RRID:SCR_005095) Copy
http://purl.bioontology.org/ontology/APO
A structured controlled vocabulary for the phenotypes of Ascomycete fungi.
Proper citation: Ascomycete Phenotype Ontology (RRID:SCR_003254) Copy
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