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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://drive5.com/usearch/manual/uchime_algo.html
An algorithm for detecting chimeric sequences.
Proper citation: UCHIME (RRID:SCR_008057) Copy
http://anya.igsb.anl.gov/Geneways/GeneWays.html
A system for automatically extracting, analyzing, visualizing and integrating molecular pathway data from the research literature. The system focuses on interactions between molecular substances and actions, providing a graphical consensus view on the collected information. GeneWays is designed as an open platform, allowing researchers to query, review and critique the integrated information. Knowledge integration in the domain of molecular biology is crucial for a deeper understanding of molecular cell functions. Integration can be accomplished by gathering research results published in the scientific literature. Unfortunately, researchers are facing a true challenge how to best integrate the sheer amount of scientific publications available. GeneWays is built to help integrating research results by providing automatic tools to gather knowledge from the scientific literature. The GeneWays project team comprises experts from biology, computer science and linguistics, who use natural language processing (NLP) to scan thousands of research articles in order to automatically extract relevant molecular knowledge. The key idea is rather simple: While a single author may be an ultimate expert on a specific molecular substance, the collective knowledge of the whole research community is currently unavailable in an integrated form. Molecular interactions are frequently represented in research articles by statements such as protein A activates protein B, which can be collected and integrated into knowledge about a complex molecular network consisting of thousands of genes, proteins, small molecules (along with other substances) and their interactions. GeneWays's architecture combines various modules designed to automatically gather knowledge on signal transduction pathways from online scientific journals. The core of the system is a knowledge base of molecular actions. The knowledge is provided by various system modules, which select scientific journals of interest, mark and identify substance names in the journal text and extract interactions between these substances and other actions by means of natural language processing (NLP). The integrated knowledge stored in a database can be queried, analyzed, critiqued and visualized by interested researchers.
Proper citation: GeneWays: A System for Extracting, Analyzing, Visualizing and Integrating Molecular Pathway Data (RRID:SCR_008368) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics.
Proper citation: QIIME (RRID:SCR_008249) Copy
http://cran.r-project.org/web/packages/RJaCGH/index.html
Software for Bayesian analysis of CGH microarrays fitting Hidden Markov Chain models.
Proper citation: RJaCGH (RRID:SCR_008381) Copy
http://www.cerc.utexas.edu/OnlineCall/
A fast basecalling scheme for Illumina''s Next Generation sequencing machines, specifically designed for GAII.
Proper citation: OnlineCall (RRID:SCR_008263) Copy
http://bioinfo.cipf.es/isacghtrac
Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations.
Proper citation: IsaCGH (RRID:SCR_008375) Copy
Database for microarray data storage, retrieval, analysis, and visualization.
Proper citation: UNC Microarray Database (RRID:SCR_010979) Copy
http://www.bcgsc.ca/platform/bioinfo/software/abyss-explorer
An interactive Java application that employs a novel graph-based representation to display a sequence assembly and associated meta data.
Proper citation: ABySS-Explorer (RRID:SCR_010980) Copy
http://dnptrapper.sourceforge.net/
An assembly editing and visualization tool specifically designed for manual analysis and finishing of repeated regions.
Proper citation: DNPTrapper (RRID:SCR_010981) Copy
http://sourceforge.net/apps/mediawiki/amos/index.php?title=Hawkeye
A visual analytics tool for genome assembly analysis and validation, designed to aid in identifying and correcting assembly errors.
Proper citation: Hawkeye (RRID:SCR_010982) Copy
http://www.raetschlab.org/suppl/palmapper
Computes both spliced and unspliced alignments at high accuracy while taking advantage of base quality information and splice site predictions.
Proper citation: PALMapper (RRID:SCR_011466) Copy
http://sourceforge.net/projects/seqexpress/
A cross-platform software that estimates gene/isoform expression level via mRNA-Seq data. SeqExpress exams the Sequencing bias in mRNA-Seq and correct it to get more accurate estimation.
Proper citation: SeqExpress (RRID:SCR_004013) Copy
Tool for extensively testing the discriminatory power of biologically relevant gene sets in microarray data classification. While the user can work with different gene set collections and several microarray data files to configure specific classification experiments, the tool is able to run several tests in parallel. It is able to render valuable information for diagnostic analyses and clinical management decisions based on systematically evaluating custom hypothesis over different data sets using complementary classifiers, a key aspect in clinical research.
Proper citation: GeneCommittee (RRID:SCR_004168) Copy
http://genomics.princeton.edu/AndolfattoLab/MSG.html
A pipeline of scripts to assign ancestry to genomic segments using next-gen sequence data. This method can identify recombination breakpoints in a large number of individuals simultaneously at a resolution sufficient for most mapping purposes, such as quantitative trait locus (QTL) mapping and mapping of induced mutations.
Proper citation: MSG (RRID:SCR_004161) Copy
http://taylorlab.ucsf.edu/software_data.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documentedt on January 10, 2023. Software that implements babel routines for identifying unusual ribosome protected fragment counts given mRNA counts, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Babel (RRID:SCR_004307) Copy
http://code.google.com/p/perm/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package to perform highly efficient genome scale alignments for hundreds of millions of short reads produced by the ABI SOLiD and Illumina sequencing platforms. It capable of providing full sensitivity for alignments within 4 mismatches for 50bp SOLID reads and 9 mismatches for 100bp Illumina reads.Efficient mapping of short sequencing reads with periodic full sensitive spaced seeds.
Proper citation: PerM (RRID:SCR_004223) Copy
Initiative to develop a systematic, evidence-based process for evaluating genetic tests and other applications of genomic technology that are rapidly moving from research to use in clinical practice. A key objective of this process is to provide objective, timely, and credible information that is clearly linked to the scientific evidence on specific applications of genetic and genomic tests. The primary focus of EGAPP activities is an independent, nonfederal expert panel, the EGAPP Working Group. Other components of the EGAPP initiative include a federal interagency, the CDC staff and consultants, and an EGAPP initiative evaluation team.
Proper citation: EGAPP (RRID:SCR_004189) Copy
http://sourceforge.net/projects/hlaseq/
An open-source software tool for accurate genotyping the human HLA genes from Illumina GA high-throughput sequencing data.
Proper citation: HLASeq (RRID:SCR_004185) Copy
http://pass.cribi.unipd.it/cgi-bin/pass.pl
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 9, 2023. A bisulfite aligner suitable for whole methylome analysis of Illumina and SOLiD reads.
Proper citation: PASS-bis (RRID:SCR_004176) Copy
http://kwanlab.bio.cuhk.edu.hk/BSRD/
A repository for bacterial small regulatory RNA. They welcome you to submit new experimental validated sRNA targets.
Proper citation: BSRD (RRID:SCR_004249) Copy
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