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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
DFCI Blais Proteomics Center
 
Resource Report
Resource Website
DFCI Blais Proteomics Center (RRID:SCR_009748) access service resource, core facility, service resource Core facility that provides the following services: Mass spectrometry service.

The Blais Proteomics Center develops and applies state-of-the-art proteomics, informatics, and related technologies for direct interrogation of protein expression, modification, and function in response to biological perturbation in cell-based models of human cancer and primary tissues. The Blais Proteomics Center serves as a valuable resource to support individual research labs at the Dana-Farber and throughout the surrounding research community. As a key component of Dana-Farber?s Strategic Plan for Research, Blais Proteomics actively participates with other Dana-Farber Strategic Research Centers in large-scale studies, designed to leverage disparate capabilities in pursuit of novel, in-depth, and otherwise unattainable insights into human biology and disease. Consistent with our role as a world-class, center of excellence in proteomics science, members of the Blais Proteomics center contribute to the teaching mission at Harvard Medical School and participate in outreach activities designed to introduce and train young scientists and others who may not otherwise have access to these advanced technologies.
mass spectrometry assay is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156209 http://blais.dfci.harvard.edu/ SCR_009748 2026-09-05 06:33:32 0
DFCI Clinical Research Laboratory
 
Resource Report
Resource Website
DFCI Clinical Research Laboratory (RRID:SCR_009749) access service resource, core facility, service resource Core facility that provides the following services: Separation of plasma and serum from blood samples, Mononuclear cell counting and isolation, DNA isolation, 24 hour urine volume and aliquoting, Research specimen processing, Bone marrow aspiration and blood fixation, Research specimen storage.

The Clinical Research Laboratory (CRL) utilizes protocol-driven standard operating procedures for the processing of pharmacokinetics, pharmacodynamic, and biomarker samples. This includes the processing, storage, and tracking of all research specimens to ensure the successful completion of clinical trials associated with patient treatment. The CRL is dedicated to the highest standards of specimen handling to maintain the integrity of data procurement and analysis for clinical trials.
material component separation, cell separation, dna extraction, clinical monitoring, clinical assay, fixation, material storage is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156210 http://www.dana-farber.org/Research/Core-Facilities.aspx SCR_009749 2026-09-05 06:33:32 0
DFCI Biohazard Containment Core Facility
 
Resource Report
Resource Website
DFCI Biohazard Containment Core Facility (RRID:SCR_009746) access service resource, core facility, service resource The Biocontainment Core Facility supports researchers whose experiments require a Biosafety Level 2 enhanced (BL2+) containment level. The Biocontainment Core adheres to Biosafety Level 3 (BL3) practices. Protective apparel, equipment, and other materials are provided by the core. Two core facilities are available: one is located at the Jimmy Fund building at Dana Farber; the second at The Center for Life Science. Authorized core users may have access to both facilities. Use of the facility is limited to researchers who receive training in BL3 procedures and comply with authorized user requirements. Training is provided by the Biosafety Officer, Core Manager, and authorized users. is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156207 http://www.dana-farber.org/Research/Core-Facilities.aspx#biocontainment SCR_009746 2026-09-05 06:33:32 0
DFCI Animal Resources Facility
 
Resource Report
Resource Website
DFCI Animal Resources Facility (RRID:SCR_009745) access service resource, core facility, service resource Core facility that provides the following services: Mouse breeding management, Mouse irradiation service, Technical services for laboratory animal experimentation, Veterinary care, Animal care training.

The facility provides services and resources for investigators looking to accomplish animal research objectives. This includes housing mice and rats, purchasing animals, training researchers regarding proper animal care and use, and monitoring the safety of all personnel with laboratory animal contact in conjunction with Dana-Farber?s Environmental Health and Safety and Occupational Health Services. Dana-Farber has established an Institutional Care and Use Committee (IACUC) to oversee the Institute?s animal program, facilities, and projects involving the use of animals. The IACUC serves as the approval body for all protocols involving animal research, and assists faculty, students and staff in upholding Dana-Farber?s commitment to providing the finest care and most humane utilization of laboratory animals. In addition to basic husbandry services, the ARF staff provides technical and veterinary services, mouse breeding management and mouse irradiation.
laboratory animal care, rodent irradiation is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156206 http://www.dana-farber.org/Research/Core-Facilities.aspx#animal SCR_009745 2026-09-05 06:33:32 0
DF/HCC Tissue Microarray and Imaging Core Facility
 
Resource Report
Resource Website
DF/HCC Tissue Microarray and Imaging Core Facility (RRID:SCR_009743) access service resource, core facility, service resource Core facility that provides the following services: Construction of standard and custom TMA service, Nucleic acid isolation from paraffin embedded tissue service, Immunofluorescent staining service, Access to the Automated Quantitative Analysis (AQUA) system, Tissue microarray consultation service.

The mission of the Tissue Microarray and Imaging Core is to generate tissue microarrays by allowing placement of up to 480 0.6 mm diameter tissue samples into a single standard tissue block, allowing hundreds of tumors and samples to be evaluated on a single slide. The DF/HCC Tissue Microarray & Imaging (TMI) Core is dedicated to the construction and evaluation of high quality TMAs for cancer research. In addition, the Core performs high-throughput isolation of DNA and RNA from formalin-fixed paraffin-embedded tissues. The Core also provides web-based digital pathology services using the Aperio system. These services include slide scanning, image viewing and storage, and quantitative image analysis, which facilitate tissue-based research. Finally, the Core provides access to the Automated Quantitative Analysis (AQUA) system.
nucleic acid microarray assay, nucleic acid isolation, staining, immunofluorescence microscopy assay, digital imaging is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156204 http://harvard.eagle-i.net/i/0000012c-adf9-c87f-02c0-2b6880000000 SCR_009743 2026-09-05 06:33:32 0
DF/HCC Monoclonal Antibody Core
 
Resource Report
Resource Website
DF/HCC Monoclonal Antibody Core (RRID:SCR_009740) access service resource, core facility, service resource Core facility that provides the following services: Protein development/cloning, Western blot service, ELISA service, Flow cytometry service.

The mission of the DF/HCC Monoclonal Antibody Core (MAC) is to produce novel monoclonal antibodies that are directed against antigens of interest to Dana-Farber, the Harvard Cancer Center, and affiliated investigators. These monoclonal antibodies may be useful for basic research, drug discovery and clinical applications including diagnosis, surrogate markers for disease status, response to therapy or drug toxicity. Given the diverse research needs of investigators at DFCI and the Harvard Community, the MAC should strive to support a wide range of antibody requests. A key component of the DF/HCC MAC is the ability to explore and develop new technologies that facilitate generation of monoclonal antibodies. The DF/HCC MAC should be capable of supporting all basic functions of generating, screening, storing and producing monoclonal antibodies.
material processing, western blot analysis, elisa, cell staining is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156200 https://dfci.ilabsolutions.com/service_center/show_external/6059/dfci-monoclonal-antibody-core SCR_009740 2026-09-05 06:33:32 0
Dartmouth SYNERGY: Ethics Consultation Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Ethics Consultation Core (RRID:SCR_009775) Dartmouth ECC access service resource, core facility, service resource The Ethics Consultation Core (ECC) leverages current ethics activities across Dartmouth, and thus provides the capacity for real-time collaborative ethics advice for investigators throughout the translational research community. is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156239 SCR_009775 2026-09-05 06:33:33 0
Dartmouth SYNERGY: Biostatistics Consultation Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Biostatistics Consultation Core (RRID:SCR_009773) Dartmouth BCC access service resource, core facility, service resource The BCC provides essential statistical and quantitative methods support to Dartmouth investigators, helping to remove impediments to initiating new clinical translational research programs for young physicians and other scientists. Specialized support for statistical genetics/genomics, decision sciences and comparative effectiveness research, health services research, mathematical demography, psychometrics, geographic information systems, and imaging applications. The BCC also provides statistical expertise related to critical data management, in cooperation with the SYNERGY Biomedical Informatics Core, and fully supports statistical education initiatives throughout SYNERGY is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156237 http://synergy.dartmouth.edu/research_core_bcc.html SCR_009773 2026-09-05 06:33:33 0
Dartmouth Molecular Biology Shared Resource
 
Resource Report
Resource Website
Dartmouth Molecular Biology Shared Resource (RRID:SCR_009766) access service resource, core facility, service resource Core facility that provides the following services: Genotyping service, DNA sequencing service, DNA fragment analysis.

DNA Sequencing, DNA Fragment Analysis
polymerase chain reaction, genotyping assay, southern blot analysis, dna sequencing, nucleic acid fragment analysis, amplified fragment length polymorphism pcr, microsatellite analysis, single-nucleotide polymorphism analysis is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156230 http://www.dartmouth.edu/~mbcf/index.shtml SCR_009766 2026-09-05 06:33:33 0
Dartmouth Multi-Photon Imaging
 
Resource Report
Resource Website
Dartmouth Multi-Photon Imaging (RRID:SCR_009767) access service resource, core facility, service resource Core facility that provides the following services: Multi-photon imaging. This SynergyT1 Shared Resource Core includes two microscopes sharing two femtosecond pulsed Ti:Sapphire lasers (tunable between 690 and 1080 nm) for imaging fluorescently-tagged molecules in tissues in vivo and in vitro. fluorescent microscopy is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156231 http://synergy.dartmouth.edu/research_t1_shared_cores.html SCR_009767 2026-09-05 06:33:33 0
Dartmouth Electron Microscope Facility
 
Resource Report
Resource Website
Dartmouth Electron Microscope Facility (RRID:SCR_009762) access service resource, core facility, service resource Core facility that provides the following services: Electron micrscopy facility access.

The EM Facility is an institutional resource to meet the electron microscopy needs of faculty, staff and students of the Dartmouth College community, including the College, Thayer School of Engineering, the Dartmouth Medical School, and the Dartmouth-Hitchcock Medical Center. The instruments are housed in the EM wing of Remsen. Because the facility is intended to provide service to all the campus, yet has limited personnel, a major effort is made to provide training in the use of appropriate instruments to enable users to do their own microscopy. In addition to this training, there will be service assistance available for those unable to spend time on the microscopes, and for processing of biopsy samples from DHMC.
electron microscopy is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156225 http://www.dartmouth.edu/~emlab/ SCR_009762 2026-09-05 06:33:33 0
Dartmouth Genomics Shared Resource
 
Resource Report
Resource Website
1+ mentions
Dartmouth Genomics Shared Resource (RRID:SCR_009763) access service resource, core facility, service resource Core facility that provides the following services: Illumina Bead Array service, Affymetrix Microarray service.

The Genomics Shared Resource provides technologies to the Norris Cotton Cancer Center and Dartmouth community investigators that enable profiling of gene expression, miRNA, GpC Island, and CGH on a whole-genome scale. The long-term goal of the Genomics Shared Resource is to provide an efficient and affordable fee-for-service operation that will provide high quality genomics and microarray data for the growing number of Cancer Center investigators who require this service.
nucleic acid microarray assay is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156226 http://dartmouth.eagle-i.net/i/0000012e-0783-585d-4bd3-f7c180000000, http://cancer.dartmouth.edu/res/genomics.html, https://freedom7.dartmouth.edu/login SCR_009763 2026-09-05 06:33:33 1
Dartmouth Cigarette Smoke Exposure Analysis Laboratory
 
Resource Report
Resource Website
Dartmouth Cigarette Smoke Exposure Analysis Laboratory (RRID:SCR_009761) access service resource, core facility, service resource Core facility that provides the following services: Cigarette smoke exposure analysis service.

Our lab is interested in the innate immune system at the mucosal surfaces of the female reproductive and respiratory tracts. A special focus of this work is to determine the effects of cigarette smoke on changes in immune protection. The relationship of cigarette smoke exposure to increased risk of infection is well established, however the mechanisms involved are not. Our research shows that cigarette smoke exposure reduces production of a key antimicrobial chemokine, CCL20. Ongoing research in the lab seeks to determine if similar responses to cigarette smoke exposure underlie increased rates of infection and how cigarette smoke exposure associated infection is linked to the development of cancer. Consulting; training; planning; experimental management assistance. Banked tissue samples available for preliminary studies. Small animal cigarette exposure.
high throughput sample analysis is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156222 http://dms.dartmouth.edu/faculty/facultydb/view.php?uid=3392 SCR_009761 2026-09-05 06:33:33 0
CHB Molecular Genetics Core Facility
 
Resource Report
Resource Website
CHB Molecular Genetics Core Facility (RRID:SCR_009715) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8,2024. Core facility that provides the following services: DNA sequencing (standard) service, Taqman gene expression service, Taqman SNP genotyping, Digital PCR service, Genomic mapping facility standard service, DNA purification from blood and saliva, RNA purification service, Master 96-well plate sample preparation, Gene expression service, SNP genotyping service, Bioanalysis of RNA and DNA, Next-generation sequencing service, Sequenom SNP genotyping, SNP and qPCR 7900HT instrument access. The Molecular Genetics Core Facility (MGCF) is a non-profit core laboratory in the Program in Genomics and Genetics Division of Children''s Hospital Boston offering genomics services for academic research institutions. The majority of MGCF users are investigators from Children''s Hospital Boston and the surrounding Harvard affiliates, but the MGCF also serves laboratories throughout the entire United States. The MGCF is comprised of a compilation of smaller cores partially supported by private and federal funds. Funding is provided in part through The Intellectual and Developmental Disabilities Research Center, The Manton Center for Orphan Disease Research, The Wellstone Center for Muscular Dystrophy, and The Neuromuscular Disease Project of the Program in Genomics at Children''s Hospital Boston. The overall objective of the MGCF is to provide a location where researchers can have access to high quality, low cost genomic technology services and expertise in a timely, affordable manner. The services offered include DNA sequencing, Next-Gen sequencing, Affymetrix and Illumina whole-genome expression and genotyping microarray technology, microsatellite genotyping, high-throughput qPCR and SNP services on the Fluidigm Biomark System, multiplex SNP genotyping on the Sequenom MassARRAY, and sample extraction and banking. The MGCF also assists investigators with project design and collaborates on linkage and association study analysis. polymerase chain reaction, dna sequencing, gene expression analysis assay, genotyping assay, microsatellite analysis, dna purification, purification, sample preparation for assay, rna quality analysis, dna quality analysis, next generation sequencing, real-time pcr, single-nucleotide polymorphism analysis is listed by: Eagle I THIS RESOURCE IS NO LONGER IN SERVICE nlx_156175 http://harvard.eagle-i.net/i/0000012c-bcb1-7724-02c0-2b6880000000, http://core.iddrc.org/molecular-genetics/ SCR_009715 2026-09-05 06:33:32 0
CHB Molecular and Cellular Biochemistry Core
 
Resource Report
Resource Website
CHB Molecular and Cellular Biochemistry Core (RRID:SCR_009716) access service resource, core facility, service resource Core facility that provides the following services: Lipoprotein analysis, Biliary lipid concentrations analysis, Biliary particle analysis, Quantitative real-time PCR, Sequential ultracentrifugation for lipoproteins, Radiolabeling of lipoproteins, Fluorescence labeling of lipoproteins, Purification of biliary lipid aggregatesfrom model biles, Preparation of recombinant proteins, Protein identification from gel bands, Protein Identification from complex mixtures. The Molecular and Cellular Biochemistry Core is dedicated to providing HDDC investigators and their trainees with access to a variety of methods to determine the compositions of tissues, as well as their cellular and subcellular specimens. The Core Scientists offer a broad range of analyses and preparatory services including Proteomics. Importantly, the Core also provides training in the application of state-of-the-art techniques in molecular analysis of proteins, lipids and nucleic acids. The main Core laboratory is located at Brigham and Women?s Hospital (BWH) and the satellite Core laboratory is located at Children?s Hospital Boston (CHB). We perform a broad array of biochemical and analytical assays that are not typically available within laboratories of HDDC members. These have generally been adapted so that they may be performed in large numbers on microplates. These include quantification of lipids, mRNA and protein and a full array of mass spectroscopy services for protein analysis (and soon to be expanded for lipidomics). We also offer both analytical and preparatory separations by a variety of methods. material component separation, high performance liquid chromatography, real-time pcr, centrifugation, radiolabeling, immunofluorescence microscopy assay, purification, recombinant protein production, mass spectrometry assay, protein identification is listed by: Eagle I nlx_156176 http://www.hms.harvard.edu/hddc/services/proteomic/ SCR_009716 2026-09-05 06:33:32 0
CHB Magnetic Resonance Imaging
 
Resource Report
Resource Website
CHB Magnetic Resonance Imaging (RRID:SCR_009714) access service resource, core facility, service resource Core facility that provides the following services: Magnetic resonance imaging (MRI) access. Magnetic Resonance Imaging (MR or MRI) at Children''s Hospital Boston performs pediatric MRIs in a friendly, child-centered environment designed to make your child''s experience as pleasant as possible. Our dedicated staff has years of experience imaging children and teens. Physicians order MRI studies to rule out or diagnose diseases. The technology produces incredibly detailed pictures of your child''s organs, bones and tissues without using ionizing radiation (X-rays). Instead, it uses strong magnets, radiofrequency waves and powerful computers to generate 2- and 3-dimensional images of a given organ or body part. We use protocols and procedures developed specifically for babies and children, which means age-appropriate care for your child and the best possible images for the radiologist. magnetic resonance imaging is listed by: Eagle I nlx_156174 http://www.childrenshospital.org/clinicalservices/Site2131/mainpageS2131P0.html SCR_009714 2026-09-05 06:33:32 0
CHB Diagnostic Radiology Core
 
Resource Report
Resource Website
CHB Diagnostic Radiology Core (RRID:SCR_009711) access service resource, core facility, service resource Within Children''s Hospital Boston''s Department of Radiology, Diagnostic Radiology offers standard radiography (conventional X-rays) and fluoroscopy, an imaging technique that uses X-rays to create real-time images of the body. We perform more than 135,000 exams each year in Boston and at our satellite locations, which makes us one of the country''s largest general diagnostic centers for children. is listed by: Eagle I nlx_156171 http://www.childrenshospital.org/clinicalservices/Site2119/mainpageS2119P0.html SCR_009711 2026-09-05 06:33:32 0
BIDMC eData Collection Core
 
Resource Report
Resource Website
BIDMC eData Collection Core (RRID:SCR_009679) access service resource, core facility, service resource Core facility that provides the following services: Data acquisition service, Data storage service.

The Research Electronic Data Collection Core can help you capture research data by supporting all aspects of data acquisition, storage and retrieval. The core is designed to significantly improve the efficiency, cost structure and overall quality of research data collection. The Data Collection Core will provide expert services including: study forms design and implementation; training in all aspects of using TELEform software; database construction and exporting / preparing data for statistical applications such as SAS and SPSS; and technical assistance with scanners and computers running electronic form capture process.
data acquisition, data storage is listed by: Eagle I nlx_156136 http://bidmc.org/Research/CoreFacilities/eDataCollectionCore.aspx SCR_009679 2026-09-05 06:33:31 0
CHB Computed Tomography Core Imaging Facilities
 
Resource Report
Resource Website
CHB Computed Tomography Core Imaging Facilities (RRID:SCR_009710) access service resource, core facility, service resource Computed Tomography (CT) at Children''s Hospital Boston helps doctors quickly answer urgent questions about your child''s health. In just seconds or minutes, CT scans can produce incredibly detailed, three-dimensional images of your child''s bone, tissue and blood vessels. CT exams in our powerful multi-detector scanners are quick, painless and non-invasive. Located at two locations: Boston and Waltham. Should be contacted about scanner technology, image acquisition, etc., but not for actual access to the facility. is listed by: Eagle I nlx_156170 http://www.childrenshospital.org/clinicalservices/Site1947/mainpageS1947P0.html SCR_009710 2026-09-05 06:33:31 0
CHB Cellular Neuroscience Core Laboratory
 
Resource Report
Resource Website
CHB Cellular Neuroscience Core Laboratory (RRID:SCR_009708) access service resource, core facility, service resource Core facility that provides the following services: Rapid golgi staining service, Luxol fast blue service, Electron microscopy service, Electron microscopy embedding service, Electron microscopy sectioning service, H&E and cresyl violet staining service, Golgi Cox service, Cryostat, vibratome, and microtome usage service, Ultramicrotome usage service. The core allows investigators to perform diverse types of histological studies at several levels, including light and electron microscopy. Furthermore, since mental retardation may not be associated with structural abnormalities visible at the light microscopic level, analysis of protein expression by immunohistochemistry and gene expression by in situ hybridization are also facilitated by this Core. histology, tissue embedding, tissue sectioning, tissue fixation, electron microscopy, cryoembedding, cryosectioning is listed by: Eagle I nlx_156168 http://core.iddrc.org/cellular-neuroscience/ SCR_009708 2026-09-05 06:33:31 0

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