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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PeakRanger
 
Resource Report
Resource Website
10+ mentions
PeakRanger (RRID:SCR_010863) PeakRanger software resource Software for a multi-purpose ChIP Seq peak caller. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21554709 OMICS_00451, biotools:peakranger https://bio.tools/peakranger SCR_010863 2026-09-12 12:57:25 21
SEAL
 
Resource Report
Resource Website
100+ mentions
SEAL (RRID:SCR_010914) SEAL software resource A suite of distributed software applications for aligning short DNA reads, and manipulating and analyzing short read alignments. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21697132 biotools:seal, OMICS_00682 https://bio.tools/seal SCR_010914 2026-09-12 12:57:26 121
DIME
 
Resource Report
Resource Website
10+ mentions
DIME (RRID:SCR_010874) DIME software resource R-package for identifying differential ChIP-seq based on an ensemble of mixture models. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
biotools:DIME, OMICS_00473 https://bio.tools/DIME SCR_010874 2026-09-12 12:57:25 31
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/, https://bio.tools/bwa-sw, https://sources.debian.org/src/bwa/ SCR_010910 Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-09-12 12:57:25 2638
CloudBurst
 
Resource Report
Resource Website
CloudBurst (RRID:SCR_010911) CloudBurst software resource A new parallel read-mapping algorithm optimized for mapping next-generation sequence data to the human genome and other reference genomes, for use in a variety of biological analyses including SNP discovery, genotyping, and personal genomics. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:19357099 Free OMICS_00657, biotools:cloudburst https://bio.tools/cloudburst SCR_010911 2026-09-12 12:57:26 0
T1DBase
 
Resource Report
Resource Website
100+ mentions
T1DBase (RRID:SCR_007959) data or information resource, data repository, database, resource, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 26,2019. In October 2016, T1DBase has merged with its sister site ImmunoBase (https://immunobase.org). Documented on March 2020, ImmunoBase ownership has been transferred to Open Targets (https://www.opentargets.org). Results for all studies can be explored using Open Targets Genetics (https://genetics.opentargets.org). Database focused on genetics and genomics of type 1 diabetes susceptibility providing a curated and integrated set of datasets and tools, across multiple species, to support and promote research in this area. The current data scope includes annotated genomic sequences for suspected T1D susceptibility regions; genetic data; microarray data; and global datasets, generally from the literature, that are useful for genetics and systems biology studies. The site also includes software tools for analyzing the data. genetics, beta cell, gene, variant, region, genomics, gene expression, genome-wide association study, data analysis service, bio.tools is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is listed by: NIDDK Information Network (dkNET)
is listed by: Debian
is listed by: bio.tools
is related to: dkCOIN
has parent organization: University of Cambridge; Cambridge; United Kingdom
Type 1 diabetes. Diabetes Wellcome Trust ;
NIDDK ;
Juvenile Diabetes Research Foundation
PMID:20937630 THIS RESOURCE IS NO LONGER IN SERVICE. nif-0000-03531, biotools:t1dbase https://bio.tools/t1dbase SCR_007959 T1DBase - Type 1 Diabetes Database 2026-09-12 12:56:58 147
HilbertVis
 
Resource Report
Resource Website
1+ mentions
HilbertVis (RRID:SCR_007862) HilbertVis software resource Software tool that allows to display very long data vectors in a space-efficient manner, allowing the user to visually judge the large scale structure and distribution of features simultaneously with the rough shape and intensity of individual features. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Bioinformatics Institute
DOI:10.1093/bioinformatics/btp152 OMICS_00627, biotools:hilbertvis https://bio.tools/hilbertvis, https://sources.debian.org/src/r-bioc-hilbertvis/ SCR_007862 2026-09-12 12:56:57 4
BRIG
 
Resource Report
Resource Website
500+ mentions
BRIG (RRID:SCR_007802) BRIG software resource A cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
DOI:10.1186/1471-2164-12-402 OMICS_00929, biotools:brig https://bio.tools/brig, https://sources.debian.org/src/brig/ SCR_007802 BLAST Ring Image Generator 2026-09-12 12:56:57 561
dbEST
 
Resource Report
Resource Website
100+ mentions
dbEST (RRID:SCR_008132) data or information resource, data repository, database, service resource, storage service resource Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms. data, sequence, single, pass, cDNA, express, tag, bio.tools, gold standard is listed by: Debian
is listed by: bio.tools
has parent organization: NCBI
PMID:8401577 biotools:dbest, nif-0000-20937, r3d100010648 http://www.ncbi.nlm.nih.gov/dbEST/, https://bio.tools/dbest, https://doi.org/10.17616/R3FG8P SCR_008132 database Expressed Sequence Tag (EST), database Expressed Sequence Tag 2026-09-12 12:57:00 186
lobSTR
 
Resource Report
Resource Website
10+ mentions
lobSTR (RRID:SCR_008030) lobSTR software resource A software tool for profiling Short Tandem Repeats (STRs) from high throughput sequencing data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
PMID:22522390 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00109, biotools:lobstr https://bio.tools/lobstr SCR_008030 lobSTR - Profiling STRs in personal genomes 2026-09-12 12:56:59 47
ActiveDriver
 
Resource Report
Resource Website
10+ mentions
ActiveDriver (RRID:SCR_008104) ActiveDriver data analysis software, data processing software, sequence analysis software, software application, software resource A statistical method for interpreting variations in protein sequence (e.g. coding SNPs in the population, SNVs in cancer genomes) in the context of protein post-translational signaling modifications. Protein sequence variation, variation interpretation, protein sequence, protein post-translational signaling modifications, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:ActiveDriver, OMICS_00140 http://reimandlab.org/software/activedriver/, https://cran.r-project.org/web/packages/ActiveDriver/ActiveDriver.pdf, https://bio.tools/ActiveDriver SCR_008104 2026-09-12 12:57:00 27
QIIME
 
Resource Report
Resource Website
10000+ mentions
QIIME (RRID:SCR_008249) data analysis software, data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics. microbiome, microbial community, sequence data, data analysis software, bio.tools is used by: SortMeRNA
is used by: Nephele
is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Colorado Boulder; Colorado; USA
DOI:10.1038/nmeth.f.303 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01118, SCR_011948, OMICS_01521, biotools:qiime https://bio.tools/qiime SCR_008249 Quantitative Insights Into Microbial Ecology 2026-09-12 12:57:01 11177
IsaCGH
 
Resource Report
Resource Website
IsaCGH (RRID:SCR_008375) IsaCGH software resource Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations. microarray, array cgh, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00727, biotools:isacgh https://bio.tools/isacgh SCR_008375 2026-09-12 12:57:03 0
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) analysis service resource, production service resource, resource, service resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 Griffin 2026-09-12 12:57:02 21
FigTree
 
Resource Report
Resource Website
10000+ mentions
FigTree (RRID:SCR_008515) data processing software, data visualization software, software application, software resource A graphical viewer of phylogenetic trees and a program for producing publication-ready figures. It is designed to display summarized and annotated trees produced by BEAST. data visualization software, graphical viewer, phylogenetic tree, annotate is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: University of Edinburgh; Scotland; United Kingdom
OMICS_04268, nif-0000-30567 https://sources.debian.org/src/figtree/ SCR_008515 FigTree 2026-09-12 12:57:05 12345
BioSig: An Imaging Bioinformatics System for Phenotypic Analysis
 
Resource Report
Resource Website
100+ mentions
BioSig: An Imaging Bioinformatics System for Phenotypic Analysis (RRID:SCR_008428) BioSig data processing software, image processing software, software application, software library, software resource, software toolkit Software library for processing of electroencephalogram (EEG) and other biomedical signals like electroencephalogram (EEG), electrocorticogram (ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG), respiration, and so on. Biosig contains tools for quality control, artifact processing, time series analysis, feature extraction, classification and machine learning, and tools for statistical analysis. Many tools are able to handle data with missing values (statistics, time series analysis, machine learning). Another feature is that more then 40 different data formats are supported, and a number of converters for EEG,, ECG and polysomnography are provided. Biosig has been widely used for scientific research on EEG-based BraiN-Computer Interfaces (BCI), sleep research, and ECG and HRV analysis. It provides software interfaces several programming languages (C, C++, Matlab/Octave, Python), and it provides also an interactive viewing and scoring software for adding, and editing of annotations, markers and events. application, autocorrelation, bsd, c, c++, connectivity analysis, correlation, cross-correlation, directed transfer analysis, discriminant analysis, domain independent, eeg, meg, electrocorticography, end event related potential, format conversion, german, gnome, granger causality, information theory, kde, linux, matlab, microsoft, multivariate analysis, partial directed coherence, posix/unix-like, python, regression, spectral analysis, statistical operation, temporal transformation, time domain analysis, win32 (ms windows), windows, electrocorticogram, electrocardiogram, electrooculogram, electromyogram, respiration, signal, processing, biosignal is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: Lawrence Berkeley National Laboratory
DOI:10.1109/MC.2008.407 Free, Available for download, Freely available nif-0000-30190 http://www.nitrc.org/projects/biosig, https://sources.debian.org/src/biosig-tools/ SCR_008428 2026-09-12 12:57:04 165
CAT
 
Resource Report
Resource Website
10+ mentions
CAT (RRID:SCR_008421) CAT software resource A repository of tools for analysis and annotation of CAZYmes (Carbohydrate Active enZYmes)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01676, biotools:CAt https://bio.tools/CAT SCR_008421 2026-09-12 12:57:03 13
Augustus
 
Resource Report
Resource Website
1000+ mentions
Augustus (RRID:SCR_008417) data analysis software, data processing software, sequence analysis software, software application, software resource, web application Software for gene prediction in eukaryotic genomic sequences. Serves as a basis for further steps in the analysis of sequenced and assembled eukaryotic genomes. software, gene, prediction, eucaryotic, genomic, sequence is used by: BRAKER
is used by: BRO_annotation
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
works with: Gsnap2Augustus
Deutsche Forschungsgemeinschaft (DFG) HO4545/1-1;;
STA1009/6-1 ;
Institute for Mathematics and Computer Science ;
Ernst Moritz Arndt University of Greifswald
PMID:23700307
DOI:10.1093/bioinformatics/btw494
Free, Available for download, Freely available SCR_015981, OMICS_07777, nif-0000-30133 https://sources.debian.org/src/autodock-vina/ SCR_008417 Augustus: Gene Prediction, WebAUGUSTUS, Augustus, Augustus [gene prediction] 2026-09-12 12:57:03 3886
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) data analysis software, data processing software, sequence analysis software, software application, software resource Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-09-12 12:58:23 1
DOGMA
 
Resource Report
Resource Website
100+ mentions
DOGMA (RRID:SCR_015060) software resource, web application Web-based annotation tool for plant chloroplasts and animal mitochondrial genomes. DOGMA allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. chloroplast, mitochondria, genome annotation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
PMID:15180927 Freely available biotools:DOGMA https://bio.tools/DOGMA SCR_015060 Dual Organellar GenoMe Annotator, Dual Organellar GenoMe Annotator (DOGMA) 2026-09-12 12:58:25 428

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