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http://www.scienceexchange.com/facilities/vib-compound-screening-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Compound screening facility that has several drug-like compound collections available that amount to a total of about 74,000 compounds and a human siRNA library that targets almost 8,000 genes. State-of-the-art liquid handling systems and detection technologies are available for screening in-house or custom collections in 96- or 384-well plate format. The platform is compatible with biochemical assays, cell-based assays in a broad range of cellular systems and assays in the model plant Arabidopsis thaliana. Its core activities consist of managing the VIB screening collections, assisting researchers in assay development / automation and performing high-throughput screenings. After hit clustering and selection, the VIB-CSF team can contribute in structure-activity analysis, IC50 measurements, cytotoxicity analysis, secondary screening for hit validation and counter screening for specificity analysis.

Proper citation: VIB Compound Screening Facility (RRID:SCR_012256) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/the-laboratory-for-developmental-biology

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Laboratory for Developmental Biology was established to help scientists at the Institute of Molecular Medicine and the University of Texas conduct research that requires the production of transgenic and knock-out animal models of human diseases.

Proper citation: UTHealth Laboratory for Developmental Biology (RRID:SCR_012259) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/chemodiversity-laboratory-cddi

The chemodiversity core facility offers a library of natural product-derived crude extracts, fractions and pure compounds for screening. Gas chromatography high-resolution mass spectrometry (MS) analysis, liquid chromatography MS targeted separation and high throughput screening (targeting solid tumor cell lines, anti-microbial activity, permeability and drug solubility determination) are provided. The services also include general chromatography (MPLC, HPLC) and spectrometric characterization (UV, IR) as well as microbiology workspace (biosafety cabinets), synthesis activities and training. Our facility offers advanced instrumentation (GC/MS Q-TOF, IR, UV, MPLCs, HPLCs, liquid handling robots, biosafety cabinets, and other essential lab equipment), consultation and services for sample isolation and analysis, derivatization and scale-up. Sample preparation and safety training are also available for commercial and USF clients using our chromatographic and analytical instrumentation.

Proper citation: USF Chemodiversity Laboratory (RRID:SCR_012262) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mass-spectrometry-biological-applications-and-high-throughput-proteomics-facility-cddi

The Mass Spectrometry, Biological Applications and High-Throughput Proteomics Facility is dedicated to the identification and quantification of components associated with complex biological matrices. The main goal of our lab is to produce high quality data related to any biological or environmental sample, i.e. cancer, Alzheimer_������_s, diabetes, cardiovascular disease, and parasitology, to name a few. To see a full list of facility activity, please visit our listed website.

Proper citation: USF Mass Spectrometry Biological Applications and High-Throughput Proteomics Facility (RRID:SCR_012261) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mcgill-spr-facility

For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (_������������bait_������_) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner _������������target_������_) are then flowed overtop.

Proper citation: McGill SPR Facility (RRID:SCR_012265) Copy   

•   Source: SciCrunch Registry

https://www.usf.edu/arts-sciences/departments/chemistry/research/core-facilities/nmr.aspx

NMR facility provides state-of-the-art ultra-high field (14 and 18 Tesla) instruments that enable researchers to characterize protein structure at atomic resolution (along with the characterization of small molecules). Technical support and training are available for all aspects of project development. Experiments include structure elucidation of small molecules (e.g. synthetic molecules, natural products, and small peptides etc.) to studying advanced protein-ligand interactions.

Proper citation: USF NMR Laboratory (RRID:SCR_012260) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/michigan-state-university

An Portal, Core facility

Proper citation: Michigan State University Labs and Facilities (RRID:SCR_012252) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/epigendx

EpigenDx is a genomic and epigenomic research company specializing in disease biomarker discovery and molecular diagnosis. The company provides products related to DNA methylation analysis research. Currently available products include DNA methylation controls and validated DNA methylation assays for human, mouse, and rat. EpigenDx also provides products and laboratory services for scientific researchers from academic, government and industrial communities. Our commitment to quality comes from our desire and dedication to provide the best products and services to our customers. EpigenDx has knowledge and expertise in Pyrosequencing and its many applications. CpG methylation and allele quantification analysis are conducted using Qiagen-Pyrosequencing PSQ MD system, while short-read sequence analysis is carried out using Qiagen-Pyrosequencing PSQ ID system.

Proper citation: EpigenDx (RRID:SCR_012624) Copy   

•   Source: SciCrunch Registry

http://www.phalanxbiotech.com/

Group service that provides expression profiling products and services. They manufacture DNA microarrays for gene expression and microRNA profiling.

Proper citation: Phalanx Biotech Group (RRID:SCR_002717) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/igentbio

A commercial facility handling induced pluripotent stem cell (iPSC) generation, cellular characterization, teratoma formation, karyotyping, and KO-mouse generation.

Proper citation: iGentBio (RRID:SCR_002722) Copy   

•   Source: SciCrunch Registry

http://www.umc.edu/Administration/Centers_and_Institutes/Center_for_Psychiatric_Neuroscience/Core_Research_Resources.aspx

Core facility that provides access to psychiatrically characterized post-mortem brain specimens, state-of-the-art equipment, cutting-edge technologies and the technical advice of highly trained faculty members who serve as Core Directors. The sophisticated imaging systems and biotechnologically advanced molecular core resources are provided on a shared-use basis to CPN and UMMC researchers. The CPN Research Resources Cores include the Human Brain Collection Core, Animal Core, Imaging Core, Molecular Biology Core, and Information Technologies Core.

Proper citation: UMMC Center for Psychiatric Neuroscience Labs and Facilities (RRID:SCR_002688) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/university-of-florida

Portal that lists and provides information on core facilities located at the University of Florida.

Proper citation: University of Florida Labs and Facilities (RRID:SCR_002912) Copy   

•   Source: SciCrunch Registry

http://functionalbio.com/web/

A service that provides low cost DNA sequencing. They utilize microfluidic technology.

Proper citation: Functional Biosciences (RRID:SCR_000943) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/university-of-colorado-at-boulder

A portal for the core labs and facilities at the University of Colorado at Boulder.

Proper citation: University of Colorado at Boulder Labs and Facilities (RRID:SCR_001054) Copy   

•   Source: SciCrunch Registry

http://www.ezbioresearch.com

A biotechnology company that develops, manufactures and distributes molecular biology tool kits and laboratory consumable products. Services include DNA and RNA microarrays, PCR and transgenic genotyping, and DNA/RNA analysis and quality control.

Proper citation: EZ BioResearch (RRID:SCR_001050) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/model-system-genomics-duke

Portal to the Duke University Model Systems Genomics facility equipped to perform molecular genetic research in Drosophilia. Equipment includes stereo microscopes for fly pushing and microdissection, a compound microscope and a microscope equipped to view GFP and RFP as well as two inverted microscopes for embryo injections.

Proper citation: Duke Model System Genomics (RRID:SCR_001051) Copy   

•   Source: SciCrunch Registry

https://gtac.wustl.edu

Genome Access Technology Center at the McDonnell Genome Institute offers comprehensive next generation sequencing, microarray, PCR and Bioinformatic services. In addition to generating high quality genomic, transcriptomic, and proteomic data, performs data analysis and provides technological support to users. Full service facility, from hypothesis to publication. Offers advanced analysis of microarray data. Provides free initial consultation to discuss project and offers several tiers of analysis packages to best suit your needs. NGS equipment includes NovaSeqs, Seqwell II, Oxford. Microarray expression and genotyping - all platforms.

Proper citation: Washington University School of Medicine Genome Technology Access Center Core Facility (RRID:SCR_001030) Copy   

•   Source: SciCrunch Registry

http://pnabio.com

A company which provides peptide nucleic acid products for use in research. It also provides engineered nuclease services to laboratories.

Proper citation: PNA Bio (RRID:SCR_001037) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/universite-de-sherbrooke--2

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Portal, Core facility

Proper citation: Universite de Sherbrooke Labs and Facilities (RRID:SCR_001034) Copy   

•   Source: SciCrunch Registry

http://www.renovoneural.com

A specialized preclinical research organization that provides services for biological research and development on neural therapies. Renovo offers preclinical assays and 3D-electron microscopy services that provide routine and customized solutions for basic science, preclinical and clinical research, and drug development.

Proper citation: Renovo Neural (RRID:SCR_001035) Copy   

•   Source: SciCrunch Registry