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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CHOP Human Embryonic stem cell/induced pluripotent stem cell Core
 
Resource Report
Resource Website
1+ mentions
CHOP Human Embryonic stem cell/induced pluripotent stem cell Core (RRID:SCR_009727) access service resource, core facility, service resource Core facility that provides the following services: Stem cell differentiation, Stem cell line propagation. The human embryonic stem cell/induced pluripotent Stem Cell (hESC/iPSC) Core generates control and patient-specific iPSC lines by cellular reprogramming using current technologies. The core has a training course in cell maintenance and growth, specialized differentiation protocols for disease modeling and drug screening, and quality-control reagents for the Children?s Hospital and University of Pennsylvania academic communities. The facility maintains five NIH-approved human ESC lines and has generated more than 60 disease-specific iPSC lines. embryonic stem cell culture, culture and propagation is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156189 SCR_009727 2026-09-12 01:03:20 1
BWH-BRI Antibody Core Facility
 
Resource Report
Resource Website
BWH-BRI Antibody Core Facility (RRID:SCR_009689) access service resource, core facility, service resource The BWH-BRI Antibody Core Facility provides high quality, purified monoclonal antibodies to the BWH research community. Because the antibodies are made in-house and require no shipping, they are available at a cost substantially lower than that of commercial vendors. Antibodies are of standardized quality and are available in two convenient aliquots: 500ugs and 10mgs. The Core maintains an inventory of commonly used antibodies, which allows orders to be filled quickly. is listed by: Eagle I nlx_156148 http://www.brighamandwomens.org/research/resources/abcore/ SCR_009689 2026-09-12 01:03:19 0
CHOP CTRC Cardiovascular Imaging Core
 
Resource Report
Resource Website
CHOP CTRC Cardiovascular Imaging Core (RRID:SCR_009722) access service resource, core facility, service resource Core facility that provides the following services: Vascular laboratory services, Vascular laboratory service, Carotid intima medial thickness measurment (IMT), Vascular laboratory service, Brachial Artery Reactivity (BART), Echocardiographic laboratory services, Exercise physiology laboratory services, Vascular laboratory service, Continuous arterial spin-labeling perfusion magnetic resonance imaging. The Cardiovascular Core provides cardiac testing services for children. The Core provides the technical services and expertise to conduct the highest quality research, provides research tests in a cost-effective manner, and provides unparalleled training opportunities in clinical research for investigators, fellows, students and technicians. ultrasonography, echocardiogram, exercise stress tests, magnetic resonance imaging is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156184 http://www.itmat.upenn.edu/ctrc/cardiovascular_related_core.shtml SCR_009722 2026-09-12 01:03:20 0
BWH Transgenic Core Facility
 
Resource Report
Resource Website
BWH Transgenic Core Facility (RRID:SCR_009688) access service resource, core facility, service resource Core facility that provides the following services: ES cell transfection (electroporation), Thawing/expansion of targeted ES cells, Microinjection of ES cells into blastocysts, Microinjection of DNA constructs into egg pronuclei for generating transgenic mice, Microinjection of BAC DNAs, DNA injection and microdissection, Lentiviral transgenics service, Injection of induced pluripotent stem cells for testing totipotency, Tail biopsy service, Breeding services, Mouse manipulation consultation. The Brigham & Women''s Hospital Transgenic Core Facility provides services for generating transgenic and knockout mice. Established in 1992, the BWH Core Facility has been providing gene targeting and microinjection services using state-of-the-art facilities and equipment. Dr. Lina Du, formerly a plastic surgeon in Beijing and an expert in microvascular surgery, performs both blastocyst and pronuclear injections. She has over 15 years of experience in embryo manipulation and the generation transgenic mice. The Core Facility has all of the equipment necessary for generation of transgenic mice including a Nikon Diaphot microscope equipped with Nomarski Optics and Narishige micromanipulators for microinjections, Nikon surgical microscopes for egg isolation ad transfer, a sutter needle puller and a de Fonbrune microforge. The facility maintains mice necessary for egg donors, egg recipients, and vasectomized males. This is a non-profit facility and charges are based upon anticipated mouse costs, maintenance of mice and equipment, and purchase of necessary surgical supplies and chemicals. The ES cell culture service has been offered for 6 years. Our staff carries out electroporation of targeting vectors into ES cells and provides investigators with DNA to identify ES cells carrying the desired recombination events. Then they expand the appropriate ES Cells for microinjection into blastocysts by the BWH Transgenic Core. embryonic stem cell electroporation, embryonic stem cell culture, blastocyst injection, transgenic mouse model generation, oocyte injection, microdissection, viral infection, tail biopsy, laboratory animal care is listed by: Eagle I nlx_156147 http://brighamandwomens.org/research/depts/pathology/transgenic/default.aspx SCR_009688 2026-09-12 01:03:19 0
CHOP CTRC Behavioral Neurosciences Core
 
Resource Report
Resource Website
CHOP CTRC Behavioral Neurosciences Core (RRID:SCR_009721) access service resource, core facility, service resource Core facility that provides the following services: Development of assessment methods for pediatric psychological, neuropsychological, and psychiatric research, Intervention development and implementation. The Behavioral Neurosciences Core provides consultation and assistance to investigators regarding psychological, neuropsychological, and psychiatric components of research studies involving pediatric subjects. Together, the services provided by the Behavioral Neurosciences Core offer research infrastructure support across the entire process of research, from pre-design consultation to development and analysis of behavioral data, and across multiple domains of functioning and outcomes. clinical trial technique, treatment portion of study execution is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156183 http://www.itmat.upenn.edu/ctrc/neurobehavioral_related_core.shtml SCR_009721 2026-09-12 01:03:20 0
BWH Flow Cytometry Core Laboratory
 
Resource Report
Resource Website
BWH Flow Cytometry Core Laboratory (RRID:SCR_009683) access service resource, core facility, service resource Core facility that provides the following services: Sorting or analysis with operator service, Calcium flux measurements service, DNA analysis service, Cell sorting service.

This lab''s mission is to provide high standard cell sorting and analysis services to the research community at the Brigham and Women?s Hospital and the Longwood Medical area.
flow cytometry assay, fluorescence activated cell sorting (facs) is listed by: Eagle I nlx_156142 http://sites.google.com/site/bwhflowcytometry/, http://www.partners.org/researchcores/cytometry/cytometry_BWH.html SCR_009683 2026-09-12 01:03:19 0
BWH CytoGenomics
 
Resource Report
Resource Website
BWH CytoGenomics (RRID:SCR_009681) access service resource, core facility, service resource Core facility that provides the following services: Fluorescence in situ hybridization.

The CytoGenomics Core provides an invaluable technical resource to the investigators of the BWH, MGH, and affiliated institutions. Services are also available to external academic and commercial laboratories; these should contact us via our website for sample submission and pricing. Cytogenetic studies can provide insight into regions of the genome that are pathogenetic in various neoplasms leading to an understanding of the molecular pathways participating in the biology of cancer. It is appropriate to consider cytogenetics as a fundamental adjunct to a variety of investigations underway, including basic and clinical research. For example, a rather simple cytogenetic analysis of mouse ES cells to determine ploidy prior to injections into blastulas leads to a greater success rate in establishing founders for knock-out and knock-in experiments. The primary chromosomal assignment of a gene by a FISH experiment may lead to correlation of a disease with that gene. Other cytogenetic studies may be important in establishing a diagnosis for correlation with clinical outcome. The advent of molecular probes for FISH analysis has facilitated cytogenetic studies in the mouse, and other model organisms and this Core aggressively implements such technologies. In addition to state-of-the-art analyses for human samples, the BWH CytoGenomics Core also performs routine mouse karyotyping and a variety of other molecular cytogenetic analyses, services not easily obtainable elsewhere.
fluorescent in situ hybridization is listed by: Eagle I nlx_156140 http://cytogenomics.bwh.harvard.edu/ SCR_009681 2026-09-12 01:03:19 0
BWH Biostatistics Center
 
Resource Report
Resource Website
BWH Biostatistics Center (RRID:SCR_009680) access service resource, core facility, service resource Biostatistics support is available to investigators in the Brigham and Women''s and Harvard Medical research community for statistical consulting on issues such as study design and data analysis for manuscripts and grant applications. Resources are limited, so planning ahead is essential. The Biostatistics Consulting Service is part of the Biostatistics Core of the BWH Center for Clinical Investigation (CCI). is listed by: Eagle I nlx_156137 http://biostatistics.bwh.harvard.edu/ SCR_009680 2026-09-12 01:03:19 0
CHB Small Animal Imaging Core Laboratory
 
Resource Report
Resource Website
CHB Small Animal Imaging Core Laboratory (RRID:SCR_009719) access service resource, core facility, service resource In recognition of the value of small animal imaging to the research community, Children''s Hospital Boston has committed to developing a state-of-the-art Small Animal Imaging Laboratory. The SAIL facility is located within the Department of Radiology''s Kresge Laboratory. is listed by: Eagle I nlx_156179 http://childrenshospital.org/cfapps/research/data_admin/Site2245/mainpageS2245P0.html SCR_009719 2026-09-12 01:03:20 0
CHB Radiopharmaceutical Chemistry Laboratory
 
Resource Report
Resource Website
CHB Radiopharmaceutical Chemistry Laboratory (RRID:SCR_009718) access service resource, core facility, service resource The radiopharmaceutical chemistry research program occupies two research laboratories in the Enders research building at Children''s: a radiopharmaceutical chemistry laboratory and a hot laboratory. A separate cell-culture laboratory is also available. The radiopharmaceutical chemistry laboratory contains four fume hoods, approximately 50 linear feet of bench space, and is set up to accommodate three postdoctoral researchers. is listed by: Eagle I nlx_156178 http://www.childrenshospital.org/sites/Site2575/mainpageS2575P38sublevel84.html SCR_009718 2026-09-12 01:03:20 0
Dartmouth Biomedical NMR Research Center
 
Resource Report
Resource Website
1+ mentions
Dartmouth Biomedical NMR Research Center (RRID:SCR_009759) access service resource, core facility, service resource Core facility that provides the following services: Animal in vivo MRI and MRS Service.

The Biomedical NMR Research Center belongs to the Research Division of the Department of Diagnostic Radiology. Dr. Barjor Gimi is currently Director of the MR center. The Center houses a 7T horizontal bore Varian MR scanner in Vail and a 9.4T horizontal bore Varian MR scanner in Borwell. Research at the Biomedical NMR Research Center aims to advance applications of NMR techniques for tissue characterization in health and disease. We are developing non-invasive MR techniques to reveal unexplored details of anatomy, physiology and biochemistry in vivo. We use multinuclear MR technique both in imaging and spectroscopy modes and work with several animal models to achieve the goals above. Biomedical NMR Research Center provides a wide range of in vivo MR protocols for Dartmouth College and Dartmouth-Hitchcock Medical Center scientists. These include high resolution anatomical and functional MRI scanning procedures from rodents. Localized ��������H and ����������������P NMR spectroscopy can be acquired from several target organs to map, for instance metabolite concentrations, energy state, intracellular pH or tissue temperature.
magnetic resonance spectroscopy is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156220 http://med.dartmouth-hitchcock.org/biomedical_nmr.html SCR_009759 2026-09-12 01:03:21 1
Dartmouth-Hitchcock Bioinformatics Shared Resource
 
Resource Report
Resource Website
Dartmouth-Hitchcock Bioinformatics Shared Resource (RRID:SCR_009758) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 29,2022. Core to support the implementation of bioinformatics resources for cancer research at Dartmouth. Provides consultation and collaboration for research projects of NCCC members, regular workshops, seminars, services including applied bioinformatics and data mining, computer programming and software engineering, database development and programming and high performance computing and systems administration. cancer, research, core, service, bioinformatics, data, mining, computer, programming, software, engineering, database, administration is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156219 http://cancer.dartmouth.edu/res/bioinformatics.html http://dartmouth.eagle-i.net/i/0000012b-3a21-22b4-bd3e-55f580000000 SCR_009758 Center, Dartmouth, Norris Cotton, Hitchcock, Dartmouth-Hitchcock, Shared Resource, BISR, Bioinformatics, Cancer 2026-09-12 01:03:21 0
DFCI Microarray Core Facility
 
Resource Report
Resource Website
DFCI Microarray Core Facility (RRID:SCR_009753) access service resource, core facility, service resource Core facility that provides the following services: Gene expression profiling service, Single nucleotide polymorphism analysis service, Tiling arrays service.

The Microarray Core provides services for genome-wide analysis of gene expression, nucleotide variation, copy number variation, and chromatin protein binding sites. The core platforms include microarrays and next generation sequencing. Consultation on experimental design, and assistance with data analysis are also available. The Microarray Core carries out gene expression profiling on 3'' arrays and on Exon arrays; genotyping and comparative genomic hybridization both on single nucleotide polymorphism (SNP) arrays, and Chromatin ImmunoPrecipitation localization (ChIP-on-Chip). All services use oligonucleotide microarrays. Biostatistical support to assist in analyzing the data is available. The services of the Core are accessible to DFCI investigators and to investigators outside of DFCI.
nucleic acid microarray assay, single-nucleotide polymorphism analysis is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156213 SCR_009753 2026-09-12 01:03:21 0
DFCI Blais Proteomics Center
 
Resource Report
Resource Website
DFCI Blais Proteomics Center (RRID:SCR_009748) access service resource, core facility, service resource Core facility that provides the following services: Mass spectrometry service.

The Blais Proteomics Center develops and applies state-of-the-art proteomics, informatics, and related technologies for direct interrogation of protein expression, modification, and function in response to biological perturbation in cell-based models of human cancer and primary tissues. The Blais Proteomics Center serves as a valuable resource to support individual research labs at the Dana-Farber and throughout the surrounding research community. As a key component of Dana-Farber?s Strategic Plan for Research, Blais Proteomics actively participates with other Dana-Farber Strategic Research Centers in large-scale studies, designed to leverage disparate capabilities in pursuit of novel, in-depth, and otherwise unattainable insights into human biology and disease. Consistent with our role as a world-class, center of excellence in proteomics science, members of the Blais Proteomics center contribute to the teaching mission at Harvard Medical School and participate in outreach activities designed to introduce and train young scientists and others who may not otherwise have access to these advanced technologies.
mass spectrometry assay is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156209 http://blais.dfci.harvard.edu/ SCR_009748 2026-09-12 01:03:20 0
DFCI Clinical Research Laboratory
 
Resource Report
Resource Website
DFCI Clinical Research Laboratory (RRID:SCR_009749) access service resource, core facility, service resource Core facility that provides the following services: Separation of plasma and serum from blood samples, Mononuclear cell counting and isolation, DNA isolation, 24 hour urine volume and aliquoting, Research specimen processing, Bone marrow aspiration and blood fixation, Research specimen storage.

The Clinical Research Laboratory (CRL) utilizes protocol-driven standard operating procedures for the processing of pharmacokinetics, pharmacodynamic, and biomarker samples. This includes the processing, storage, and tracking of all research specimens to ensure the successful completion of clinical trials associated with patient treatment. The CRL is dedicated to the highest standards of specimen handling to maintain the integrity of data procurement and analysis for clinical trials.
material component separation, cell separation, dna extraction, clinical monitoring, clinical assay, fixation, material storage is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156210 http://www.dana-farber.org/Research/Core-Facilities.aspx SCR_009749 2026-09-12 01:03:20 0
DFCI Biohazard Containment Core Facility
 
Resource Report
Resource Website
DFCI Biohazard Containment Core Facility (RRID:SCR_009746) access service resource, core facility, service resource The Biocontainment Core Facility supports researchers whose experiments require a Biosafety Level 2 enhanced (BL2+) containment level. The Biocontainment Core adheres to Biosafety Level 3 (BL3) practices. Protective apparel, equipment, and other materials are provided by the core. Two core facilities are available: one is located at the Jimmy Fund building at Dana Farber; the second at The Center for Life Science. Authorized core users may have access to both facilities. Use of the facility is limited to researchers who receive training in BL3 procedures and comply with authorized user requirements. Training is provided by the Biosafety Officer, Core Manager, and authorized users. is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156207 http://www.dana-farber.org/Research/Core-Facilities.aspx#biocontainment SCR_009746 2026-09-12 01:03:20 0
DFCI Animal Resources Facility
 
Resource Report
Resource Website
DFCI Animal Resources Facility (RRID:SCR_009745) access service resource, core facility, service resource Core facility that provides the following services: Mouse breeding management, Mouse irradiation service, Technical services for laboratory animal experimentation, Veterinary care, Animal care training.

The facility provides services and resources for investigators looking to accomplish animal research objectives. This includes housing mice and rats, purchasing animals, training researchers regarding proper animal care and use, and monitoring the safety of all personnel with laboratory animal contact in conjunction with Dana-Farber?s Environmental Health and Safety and Occupational Health Services. Dana-Farber has established an Institutional Care and Use Committee (IACUC) to oversee the Institute?s animal program, facilities, and projects involving the use of animals. The IACUC serves as the approval body for all protocols involving animal research, and assists faculty, students and staff in upholding Dana-Farber?s commitment to providing the finest care and most humane utilization of laboratory animals. In addition to basic husbandry services, the ARF staff provides technical and veterinary services, mouse breeding management and mouse irradiation.
laboratory animal care, rodent irradiation is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156206 http://www.dana-farber.org/Research/Core-Facilities.aspx#animal SCR_009745 2026-09-12 01:03:20 0
DF/HCC Tissue Microarray and Imaging Core Facility
 
Resource Report
Resource Website
DF/HCC Tissue Microarray and Imaging Core Facility (RRID:SCR_009743) access service resource, core facility, service resource Core facility that provides the following services: Construction of standard and custom TMA service, Nucleic acid isolation from paraffin embedded tissue service, Immunofluorescent staining service, Access to the Automated Quantitative Analysis (AQUA) system, Tissue microarray consultation service.

The mission of the Tissue Microarray and Imaging Core is to generate tissue microarrays by allowing placement of up to 480 0.6 mm diameter tissue samples into a single standard tissue block, allowing hundreds of tumors and samples to be evaluated on a single slide. The DF/HCC Tissue Microarray & Imaging (TMI) Core is dedicated to the construction and evaluation of high quality TMAs for cancer research. In addition, the Core performs high-throughput isolation of DNA and RNA from formalin-fixed paraffin-embedded tissues. The Core also provides web-based digital pathology services using the Aperio system. These services include slide scanning, image viewing and storage, and quantitative image analysis, which facilitate tissue-based research. Finally, the Core provides access to the Automated Quantitative Analysis (AQUA) system.
nucleic acid microarray assay, nucleic acid isolation, staining, immunofluorescence microscopy assay, digital imaging is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156204 http://harvard.eagle-i.net/i/0000012c-adf9-c87f-02c0-2b6880000000 SCR_009743 2026-09-12 01:03:20 0
DF/HCC Monoclonal Antibody Core
 
Resource Report
Resource Website
DF/HCC Monoclonal Antibody Core (RRID:SCR_009740) access service resource, core facility, service resource Core facility that provides the following services: Protein development/cloning, Western blot service, ELISA service, Flow cytometry service.

The mission of the DF/HCC Monoclonal Antibody Core (MAC) is to produce novel monoclonal antibodies that are directed against antigens of interest to Dana-Farber, the Harvard Cancer Center, and affiliated investigators. These monoclonal antibodies may be useful for basic research, drug discovery and clinical applications including diagnosis, surrogate markers for disease status, response to therapy or drug toxicity. Given the diverse research needs of investigators at DFCI and the Harvard Community, the MAC should strive to support a wide range of antibody requests. A key component of the DF/HCC MAC is the ability to explore and develop new technologies that facilitate generation of monoclonal antibodies. The DF/HCC MAC should be capable of supporting all basic functions of generating, screening, storing and producing monoclonal antibodies.
material processing, western blot analysis, elisa, cell staining is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156200 https://dfci.ilabsolutions.com/service_center/show_external/6059/dfci-monoclonal-antibody-core SCR_009740 2026-09-12 01:03:20 0
Dartmouth SYNERGY: Ethics Consultation Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Ethics Consultation Core (RRID:SCR_009775) Dartmouth ECC access service resource, core facility, service resource The Ethics Consultation Core (ECC) leverages current ethics activities across Dartmouth, and thus provides the capacity for real-time collaborative ethics advice for investigators throughout the translational research community. is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156239 SCR_009775 2026-09-12 01:03:21 0

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