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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ReadqPCR
 
Resource Report
Resource Website
ReadqPCR (RRID:SCR_000030) software application, software resource, standalone software A software package that provides functions to read raw RT-qPCR data of different platforms. standalone software, mac os x, unix/linux, windows, r, data import, gene expression, microtitre plate assay, qpcr, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: University College London; London; United Kingdom
PMID:22748112 Free, Available for download, Freely available biotools:readqpcr, OMICS_03936 https://bio.tools/readqpcr SCR_000030 ReadqPCR - Read qPCR data 2026-08-29 11:30:49 0
CRCView
 
Resource Report
Resource Website
CRCView (RRID:SCR_007092) CRCView analysis service resource, data analysis service, production service resource, service resource Web-based microarray data analysis and visualization system powered by CRC, or Chinese Restaurant cluster, a Dirichlet process model-based clustering algorithm recently developed by Dr. Steve Qin. It also incorporates several gene expression analysis programs from Bioconductor, including GOStats, genefilter, and Heatplus. CRCView also installs from the Bioconductor system 78 annotation libraries of microarray chips for human (31), mouse (24), rat (14), zebrafish (1), chicken (1), Drosophila (3), Arabidopsis (2), Caenorhabditis elegans (1), and Xenopus Laevis (1). CRCView allows flexible input data format, automated model-based CRC clustering analysis, rich graphical illustration, and integrated Gene Ontology (GO)-based gene enrichment for efficient annotation and interpretation of clustering results. CRC has the following features comparing to other clustering tools: 1) able to infer number of clusters, 2) able to cluster genes displaying time-shifted and/or inverted correlations, 3) able to tolerate missing genotype data and 4) provide confidence measure for clusters generated. You need to register for an account in the system to store your data and analyses. The data and results can be visited again anytime you log in. microarray, gene expression, cluster, gene, expression profile, data repository, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
is related to: Gene Ontology
has parent organization: University of Michigan; Ann Arbor; USA
University of Michigan; Michigan; USA ;
Institutional Fund ;
NIH U013422;
NIAID 1R21AI057875-01
PMID:17485426 Registration required biotools:crcview, nlx_99864 https://bio.tools/crcview http://helab.bioinformatics.med.umich.edu/crcview/ SCR_007092 Chinese Restaurant ClusterView 2026-08-29 11:29:56 0
epialleleR
 
Resource Report
Resource Website
1+ mentions
epialleleR (RRID:SCR_023913) software resource, software toolkit Software R package for calling hypermethylated variant epiallele frequencies at level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map files as input. Used for sensitive allele specific methylation analysis in next generation sequencing data. Used for sensitive detection, quantification and visualisation of mosaic epimutations in methylation sequencing data. BAM files, binary alignment map files, allele specific methylation analysis, methylation sequencing data, next generation sequencing data, hypermethylated variant epiallele frequencies calling, is listed by: Bioconductor K.G.Jebsen Foundation ;
Norwegian Cancer Society ;
Norwegian Research Council
DOI:10.1101/2022.06.30.498213 Free, Available for download, Freely available https://github.com/BBCG/epialleleR SCR_023913 2026-08-29 11:28:56 1
GeneNetworkBuilder
 
Resource Report
Resource Website
1+ mentions
GeneNetworkBuilder (RRID:SCR_006455) GeneNetworkBuilder software application, software resource Software application for discovering direct or indirect targets of transcription factors (TFs) using ChIP-chip or ChIP-seq, and microarray or RNA-seq gene expression data. Inputting a list of genes of potential targets of one TF from ChIP-chip or ChIP-seq, and the gene expression results, it generates a regulatory network of the TF. transcription factor, graph, network, microarray, sequencing, chip-chip, chip-seq, gene expression, regulatory network, target is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00806, OMICS_01971 http://www.bioconductor.org/packages/release/bioc/html/GeneNetworkBuilder.html SCR_006455 GeneNetworkBuilder - Build Regulatory Network from ChIP-chip/ChIP-seq and Expression Data 2026-08-29 11:30:48 2
PICS
 
Resource Report
Resource Website
1+ mentions
PICS (RRID:SCR_001093) data analysis software, data processing software, sequence analysis software, software application, software resource R package with tools that use probabilistic inference of ChIP-Seq. It follows an empirical Bayes mixture model approach. chip seq, bayes, data, r, sequence analysis software is listed by: OMICtools
is hosted by: Bioconductor
PMID:20528864 Free, Available for download, Freely available OMICS_00455 SCR_001093 Probabilistic inference of ChIP-seq 2026-08-29 11:27:24 3
DESeq2
 
Resource Report
Resource Website
10000+ mentions
DESeq2 (RRID:SCR_015687) data analysis software, data processing software, software application, software resource, software tool Software package for differential gene expression analysis based on the negative binomial distribution. Used for analyzing RNA-seq data for differential analysis of count data, using shrinkage estimation for dispersions and fold changes to improve stability and interpretability of estimates. differential, gene, expression, analysis, binominal, distribution, RNA-seq data, Bioconductor, bio.tools is used by: Glimma
is used by: TEtranscripts
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: SARTools
works with: tximport
European Union’s 7th Framework Programme ;
International Max Planck Research School for Computational Biology and Scientific Computing ;
NCI T32 CA009337
Free, Available for download, Freely available biotools:deseq2 https://github.com/mikelove/DESeq2, https://bio.tools/deseq2 SCR_015687 2026-08-29 11:27:39 50789
Extending Guilt by Association by Degree
 
Resource Report
Resource Website
1+ mentions
Extending Guilt by Association by Degree (RRID:SCR_018427) EGAD data analysis software, data processing software, software application, software resource, software toolkit Software package implements series of highly efficient tools to calculate functional properties of networks based on guilt by association methods. Ultra fast functional analysis of gene networks. Extending guilt, association by degree, functional properties calculation, guilt network, association method, functional analysis, gene network is listed by: Bioconductor Free, Available for download, Freely available SCR_018427 EGAD Bioconductor, Extending guilt by association by degree 2026-08-29 11:26:07 6
AUCell
 
Resource Report
Resource Website
50+ mentions
AUCell (RRID:SCR_021327) data analysis software, data processing software, software application, software resource, software toolkit Software R package to identify cells with active gene sets in single cell RNA-seq data. Used for analysis of gene set activity in single cell RNA-seq data.Used to calculate whether critical subset of input gene set is enriched within expressed genes for each cell. Identify cells with active gene sets, single cell RNA-seq data, gene set activity analysis is listed by: Bioconductor Free, Available for download, Freely available SCR_021327 Area Under the Curve 2026-08-29 11:28:15 56
iontree
 
Resource Report
Resource Website
iontree (RRID:SCR_002813) software resource Software package that provides utility functions to manage and analyse MS2/MS3 fragmentation data from ion trap mass spectrometry. It was designed for high throughput metabolomics data with many biological samples and a large numer of ion trees collected. Tests have been done with data from low-resolution mass spectrometry but could be readily extended to precursor ion based fragmentation data from high resoultion mass spectrometry. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24958264 Free, Freely available, Available for download OMICS_02656, biotools:iontree https://bio.tools/iontree SCR_002813 iontree: Data management and analysis of ion trees from ion-trap mass spectrometry 2026-08-29 11:28:15 0
StructuralVariantAnnotation
 
Resource Report
Resource Website
1+ mentions
StructuralVariantAnnotation (RRID:SCR_018683) data analysis software, data processing software, software application, software resource, software toolkit Software R package for structural variant analysis. Contains helper functions for dealing with structural variants in VCF format. Contains functions for parsing VCFs from number of popular callers as well as functions for dealing with breakpoints involving two separate genomic loci encoded as GRanges objects. Structural variant analysis, structural variant, VCF parsing, genomic loci, GRanger object, breakpoint is listed by: Bioconductor Free, Available for download, Freely available SCR_018683 2026-08-29 11:25:50 2
EnhancedVolcano
 
Resource Report
Resource Website
500+ mentions
EnhancedVolcano (RRID:SCR_018931) data processing software, data visualization software, software application, software resource Software R package to produce publication ready volcano plots with enhanced colouring and labeling. Used to visualise results of differential expression analyses. Publication ready plot, enhanced coloring, enhanced labeling, data visualisation, differential expression analyses, plot, volcano plot uses: ggplot2
uses: ggrepel
is listed by: Bioconductor
Free, Available for download, Freely available https://github.com/kevinblighe/EnhancedVolcano SCR_018931 2026-08-29 11:26:15 604
DEGreport
 
Resource Report
Resource Website
10+ mentions
DEGreport (RRID:SCR_018941) data analysis software, data processing software, software application, software resource Software R package for creation of HTML report of differential expression analyses of count data. Integrates some of code mentioned in DESeq2 and edgeR vignettes, and reports ranked list of genes according to fold changes mean and variability for each selected gene. HTML report creation, differential expression analyses, count data, code integration, gene list report is listed by: Bioconductor Free, Available for download, Freely available http://lpantano.github.io/DEGreport SCR_018941 2026-08-29 11:25:54 22
biomaRt
 
Resource Report
Resource Website
1000+ mentions
biomaRt (RRID:SCR_019214) data analysis software, data processing software, software application, software resource Software package that integrates BioMart data resources with data analysis software in Bioconductor. Can annotate range of gene or gene product identifiers including Entrez Gene and Affymetrix probe identifiers with information such as gene symbol, chromosomal coordinates, Gene Ontology and OMIM annotation. Enables retrieval of genomic sequences and single nucleotide polymorphism information, which can be used in data analysis. BioMart databases, Bioconductor, data analysis, BioMart data integration, gene annotation, gene product identifiers annotation, gene symbol retrival, chromosomal coordinates retrival, genomic sequence retrival, nucleotide polimorphism information, , bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: BioMart Project
is related to: BioMart MartView
is related to: Entrez Gene
is related to: Affymetrix
is related to: Gene Ontology
is related to: OMIM
is related to: Affymetrix
PMID:16082012 Free, Available for download, Freely available biotools:biomart https://bio.tools/biomart SCR_019214 biomaRt v 2.42.1 2026-08-29 11:26:19 2879
ReactomePA
 
Resource Report
Resource Website
50+ mentions
ReactomePA (RRID:SCR_019316) data analysis software, data processing software, data visualization software, software application, software resource Software R package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization. pathway analysis, REACTOME pathway, REACTOME database, enrichment analysis, gene set enrichment analysis, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
PMID:26661513 Free, Available for download, Freely available biotools:reactomepa https://bio.tools/reactomepa SCR_019316 Reactome Pathway Analysis 2026-08-29 11:26:20 86
MSnbase
 
Resource Report
Resource Website
10+ mentions
MSnbase (RRID:SCR_019317) data analytics software, data processing software, data visualization software, software application, software resource, software toolkit Software R package provides infrastructure for manipulation, processing and visualisation of mass spectrometry and proteomics data, ranging from raw to quantitative and annotated data. Used for isobaric tagged mass spectrometry data visualization, processing and quantitation. Mass spectrometry data processing, mass spectrometry data visualization, raw mass spectrometry data is listed by: Bioconductor BBSRC Tools and Resources Development Fund ;
European Union 7th Framework Program
PMID:22113085
PMID:32902283
Free, Available for download, Freely available SCR_019317 2026-08-29 11:26:02 10
GEO2R
 
Resource Report
Resource Website
50+ mentions
GEO2R (RRID:SCR_016569) data analysis software, data processing software, software application, software resource Software as an interactive web tool to compare two or more groups of samples in a Gene Expression Omnibus (GEO) series regardless of data type and quality. Used to identify genes that are differentially expressed across experimental conditions. Results are presented as a table of genes ordered by significance. compare, group, sample, gene, expression, omnibus, data, identify, differentially, expressed, across, condition, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
is related to: GEOquery
is related to: LIMMA
Free, Available for download, Freely available biotools:GEO2R https://bio.tools/GEO2R SCR_016569 2026-08-29 11:25:19 76
VisR
 
Resource Report
Resource Website
1+ mentions
VisR (RRID:SCR_016658) VisR data analysis software, data processing software, data visualization software, software application, software resource, software toolkit Software as an R-based visual framework for analysis of sequencing datasets. Provides a framework for integrative and interactive analyses. visual, framework, analysis, sequencing, data, dataset, integrative, interactive, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Bioconductor
Canadian Institutes of Health Research (CIHR) and Genome BC ;
Michael Smith Foundation for Health Research ;
NSERC PGS-D
PMID:26328469 Free, Available for download, Freely available biotools:VisR https://bio.tools/VisR SCR_016658 VisRseq, VisR 2026-08-29 11:25:20 5
riboSeqR
 
Resource Report
Resource Website
1+ mentions
riboSeqR (RRID:SCR_016947) data analysis software, data processing software, software application, software resource Software tool for analysis of sequencing data from ribosome profiling experiments. Used for plotting functions, frameshift detection and parsing of sequencing data from ribosome profiling experiments. analysis, sequencing, data, ribosome, profiling, experiment, plotting, function, frameshift, detect, parsing is listed by: Bioconductor
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_016947 2026-08-29 11:25:26 4
Rsubread
 
Resource Report
Resource Website
100+ mentions
Rsubread (RRID:SCR_016945) alignment software, data analysis software, data processing software, image analysis software, software application, software resource Software R package for sequence alignment and counting for R. Used for analyses of second and third generation sequencing data, for read mapping, read counting, SNP calling, short and long read alignment, quantification and mutation discovery. Includes assessment of sequence reads, read alignment, read summarization, exon-exon junction detection, fusion detection, detection of short and long indels, absolute expression calling and SNP calling. Can be used with reads generated from any of the major sequencing platforms including Illumina GA/HiSeq/MiSeq, Roche GS-FLX, ABI SOLiD and LifeTech Ion PGM/Proton sequencers. sequence, alignment, counting, multi, seed, strategy, mapping, read, reference, genome, analysis, data, SNP, calling, mutation, discovery, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
is related to: Subread
Australian Government ;
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support
PMID:23558742 Free, Available for download, Freely available biotools:rsubread https://bio.tools/rsubread SCR_016945 2026-08-29 11:25:23 203
scran
 
Resource Report
Resource Website
100+ mentions
scran (RRID:SCR_016944) SCRAN data analysis software, data processing software, software application, software resource Software package for low-level analyses of single-cell RNA-seq data. Used for quality control, data exploration and normalization, cell cycle phase assignment, identification of highly variable and correlated genes, clustering into subpopulations and marker gene detection. low, level, analysis, scRNA-seq, data, normalization, cell, cycle, phase, gene, variable, correlation, cluster, subpopulation, marker, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
Cancer Research UK ;
EMBL ;
National Health and Medical Research Council of Australia
PMID:27909575 Free, Available for download, Freely available biotools:scran https://bio.tools/scran SCR_016944 Single-Cell Rna-seq data ANalysis, SCRAN 2026-08-29 11:25:53 100

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