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https://swissmodel.expasy.org/lddt

Web server for local superposition free score for comparing protein structures and models using distance difference tests. Superposition free score that evaluates local distance differences of all atoms in model, including validation of stereochemical plausibility.

Proper citation: lDDT (RRID:SCR_024524) Copy   

•   Source: SciCrunch Registry
  

https://github.com/adamallo/SimPhy

Software package for simulation of multiple gene families evolving under incomplete lineage sorting, gene duplication and loss, horizontal gene transfer, all three potentially leading to species tree/gene tree discordance and gene conversion. Used for phylogenomic simulation of gene, locus, and species trees.

Proper citation: SimPhy (RRID:SCR_024501) Copy   

•   Source: SciCrunch Registry
  

http://mutationassessor.org/r3/

Web server predicts functional impact of amino-acid substitutions in proteins, such as mutations discovered in cancer or missense polymorphisms. Functional impact is assessed based on evolutionary conservation of affected amino acid in protein homologs., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: Mutation Assessor (RRID:SCR_024502) Copy   

•   Source: SciCrunch Registry
  

https://github.com/pinellolab/CRISPResso2

Software pipeline designed to enable rapid and intuitive interpretation of genome editing experiments. Used for analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments.

Proper citation: CRISPResso2 (RRID:SCR_024503) Copy   

•   Source: SciCrunch Registry
  

https://silebat.github.io/FSK-Lab/openbugs.html

Software for analysing complex statistical models using Markov chain Monte Carlo methods.

Proper citation: OpenBUGS (RRID:SCR_024488) Copy   

•   Source: SciCrunch Registry
  

https://github.com/bzhanglab/AutoRT/

Software tool for peptide retention time prediction using deep learning. Supports peptide retention prediction for tryptic peptides, MHC bound peptides and PTM peptides.

Proper citation: AutoRT (RRID:SCR_024513) Copy   

•   Source: SciCrunch Registry
  

https://www.reading.ac.uk/bioinf/ModFOLD/

Web server for the global and local quality estimation of 3D protein models

Proper citation: ModFOLD (RRID:SCR_024518) Copy   

•   Source: SciCrunch Registry
  

http://metscape.ncibi.org

A software program that allows users to visualize and interpret human metabolim and expression profiling data by providing users with a bioinformatics framework. Its features include bulding and analyzing networks of genes and compounds, identifying enriched pathways from expression profiling data, and visualizing changes in metabolite data.

Proper citation: Metscape (RRID:SCR_014687) Copy   

•   Source: SciCrunch Registry
  

http://www.bic.mni.mcgill.ca/software/minc/

A medical imaging data format and an associated set of tools and libraries including a 3 level API for medical image analysis with a particular focus on the needs of research. There are also a number of tools including Registration and Non-Uniformity correction.

Proper citation: MINC (RRID:SCR_002391) Copy   

•   Source: SciCrunch Registry
  

http://www.originlab.com/index.aspx?go=PRODUCTS/Origin

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 4, 2025.Software application for data analysis and graphing. Origin contains a variety of different graph types, including statistical plots, 2D and 3D vector graphs, and counter graphs. More advance version is OriginPro which offers advanced analysis tools and Apps for Peak Fitting, Surface Fitting, Statistics and Signal Processing.

Proper citation: Origin (RRID:SCR_014212) Copy   

•   Source: SciCrunch Registry
  

http://www.ccp4.ac.uk/html/refmac5/description.html

A molecular refinement program with two main modes: REVIEW, which checks and updates the input model to establish that the geometric restraints can be properly set up, and REFINE mode, which is the standard mode and documented in keywords. In REVIEW users can: check model coordinates and write an extended output set of coordinates, find disulphide bonds and other covalent links, cis-peptides, output the sequence and REMARK records. In REFINEMENT mode users can carry out rigid body, tls, restrained or unrestrained refinement against Xray data, or idealisation of a macromolecular structure. Also in REFINEMENT mode, Refmac produces an MTZ output file containing weighted coefficients for SigmaA weighted mFo-DFcalc and 2mFo-DFcalc maps. The program is supported by CCP4.

Proper citation: Refmac (RRID:SCR_014225) Copy   

•   Source: SciCrunch Registry
  

https://www.phenix-online.org/

A Python-based software suite for the automated determination of molecular structures using X-ray crystallography and other methods. Phenix includes programs for assessing data quality, experimental phasing, molecular replacement, model building, structure refinement, and validation. It also includes tools for reflection data and creating maps and models. Phenix can also be used for neutron crystallography. Tutorials and examples are available in the documentation tab.

Proper citation: Phenix (RRID:SCR_014224) Copy   

•   Source: SciCrunch Registry
  

https://www.intelligent-imaging.com/slidebook.php

Digital microscopy software for research microscopy. It comes standard with drivers to control numerous instruments in and around the microscope. When online, data is acquired in a native-3D format over time, color and specimen locations in customizable experiment protocols. Data can be analyzed by a wide variety of tools for image processing including mathematical operations, statistics functions, analysis scripting and import to/export from MATLAB. Additional modules are available for special applications ranging from deconvolution to photomanipulation to multiphoton.

Proper citation: SlideBook (RRID:SCR_014300) Copy   

•   Source: SciCrunch Registry
  

https://www.thermofisher.com/order/catalog/product/IQLAAEGABSFAKJMAUH

Software for identifying, characterizing, and quantifying proteins in biological samples. Can be used for range of proteomics workflows such as protein and peptide identification, PTM analysis, and isobaric mass tagging for quantification. Supports multiple database search algorithms and multiple dissociation techniques., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: Proteome Discoverer (RRID:SCR_014477) Copy   

•   Source: SciCrunch Registry
  

http://www.biochem.mpg.de/5111795/maxquant

A quantitative proteomics software package for analyzing large-scale mass-spectrometric data sets. It is a set of algorithms that include peak detection and scoring of peptides, mass calibration, database searches for protein identification, protein quantification, and provides summary statistics.

Proper citation: MaxQuant (RRID:SCR_014485) Copy   

•   Source: SciCrunch Registry
  

https://uofa.ualberta.ca/biological-sciences/-/media/science/departments/biological-sciences/mbsu/fla-5000/mulitgauge20.pdf

A software application for one-dimensional electrophoretic analysis of multi-labeled fluorophores. It was designed to analyze multi-channel fluorescence data from Fujifilm FLA-5000 and FLA-8000 scanning systems. The software also works with other scanners in the BAS/FLA series and with the LAS series.

Proper citation: Multi Gauge (RRID:SCR_014299) Copy   

•   Source: SciCrunch Registry
  

http://actimetrics.com/products/clocklab/

Point and click program used to quickly analyse circadian activity data using algorithms and embedded controls to make every graph interactive and useful for data analysis. The analysis program has been used for a variety of species including mice, hamsters, rats, sheep, Drosophila, and humans. This program has three separate applications: one for data collection, one for analysis, and a chamber control program.

Proper citation: Clocklab (RRID:SCR_014309) Copy   

•   Source: SciCrunch Registry
  

http://www.ni.com/labview/

A development environment for engineers and scientists to visualize, create, and code engineering systems. The system design software is integrated with all measurement hardware and contains signal processing IP. Other features include multithreaded execution, software deployment to hardware, and program integration into a single environment.

Proper citation: LabView (RRID:SCR_014325) Copy   

•   Source: SciCrunch Registry
  

http://www.matrixscience.com/server.html

A software package and server used to identify and characterize proteins from primary sequence databases using mass spectrometry data. Mascot integrates peptide mass fingerprinting, sequence querying, and MS/MS ion searching in order to search for proteins in databases like SwissProt, NCBInr, EMBL EST divisions, contaminants, and cRAP. If a license is purchased, users may: search data sets that exceed the 1200 spectrum limit of the free version; set up automated, high throughput work; add and edit proteins and quantification methods; and search a preferred collection of sequence databases. The software package works with instruments from AB Sciex, Agilent, Bruker, Jeol, Shimadzu, Thermo Scientific, and Waters.

Proper citation: Mascot (RRID:SCR_014322) Copy   

•   Source: SciCrunch Registry
  

http://darwin.uvigo.es/software/prottest_server.html

Web-based software used for the selection of best-fit models of protein evolution., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: ProtTest (RRID:SCR_014628) Copy   

•   Source: SciCrunch Registry