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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.nanostring.com/products/geomx-digital-spatial-profiler/geomx-dsp-overview/
Integrated commercial system comprising hardware, software and nCounter chemistry that enables simultaneous, highly multiplex spatial profiling of proteins or RNA in FFPE tissues. DSP platform quantifies abundance of protein or RNA by counting unique indexing oligonucleotides assigned to each target of interest. Used to rapidly and quantitatively assess biological implications of heterogeneity within tissue samples.
Proper citation: NanoString: GeoMx Digital Spatial Profiler (RRID:SCR_021660) Copy
https://meyerinst.com/library/NanoZoomer_RS_Brochure_Catalog.pdf
High speed, high resolution digital scanner with network features. User friendly full slide scanner designed to process up to 210 slides automatically.
Proper citation: Hamamatsu: NanoZoomer 2.0-HT (RRID:SCR_021658) Copy
System includes automated cell counter for trypan blue viability for cell lines and bright field imaging and pattern recognition software to quickly and accurately identify and count individual cells. Cell count, concentration, diameter, and % viability are automatically calculated and reported.
Proper citation: McKinley: Cellometer Auto T4 (RRID:SCR_021656) Copy
https://edspace.american.edu/openbehavior/project/openfeeder/
Project related to studying reward and feeding behavior. Provides open source automatic feeding system that can be customized for food types from seeds to pellets.System integrates plexiglass tubes, Arduino Uno, motor driver, and piezo sensor to reliably deliver accurate amounts of food, and can also be built using 3D printed parts.
Proper citation: OpenFeeder (RRID:SCR_021552) Copy
Project related to auditory behavioral task data collection.Provided high throughput operant conditioning in mouse homecage system was developed by University of Maryland,College Park, scientists.Automated system for training up to hundreds of mice in auditory behavioral task features custom Matlab GUI running on desktop which connects to Raspberry Pi to administer auditory stimuli from USB soundcard and collects auditory data as well as licking data from water spout with commercially available capacitive sensors. Parts list and build instructions are readily available from paper and associated GitHub repository.
Proper citation: ToneBox (RRID:SCR_021548) Copy
https://www.nanostring.com/products/ncounter-analysis-system/ncounter-systems-overview/
System includes hardware and software. Options include nCounter SPRINT,nCounter MAX or nCounter FLEX. Platform used for multiplex analysis of up to 800 RNA, DNA, or protein targets. System can be combined with GeoMx Digital Spatial Profiler (DSP) to enable high-plex, spatially-resolved RNA, and protein quantification.
Proper citation: NanoString: nCounter Analysis System (RRID:SCR_021712) Copy
https://www.leica-microsystems.com/products/confocal-microscopes/p/dive/
Multiphoton confocal microscope with spectrally tunable detection. Equipped with 4Tune, tunable, non descanned detection unit.
Proper citation: Leica: SP8 DIVE multi photon microscope (RRID:SCR_018852) Copy
https://www.sutter.com/MICROSCOPES/mom.html
Two photon microscope capable of imaging deep within living specimens when combined with Ti:Sapphire Laser. Provides 3D objective movement and rotation allowing specimen to remain stationary.
Proper citation: Sutter: Movable Objective Microscope (RRID:SCR_018860) Copy
http://www.harvardapparatus.com/media/harvard/pdf/Inspira_557058_9.pdf
Volume Controlled Ventilator delivers desired tidal volume to animal by precisely controlling stroke of piston. Since actual stroke length may be modified for given stroke, sigh breaths are supported.
Proper citation: Harvard Apparatus: Inspira Advanced Safety Ventilator, Volume Controlled (RRID:SCR_018834) Copy
https://millar.com/Clinical/Control-Units-and-Accessories/
Pressure Control Unit is two channel, patient isolated, line powered bridge amplifier for connecting one or two single sensor Millar Mikro-Tip catheters to clinical patient monitor or standalone data acquisition system. Provides built in ridge excitation eliminating need for separate bridge amplifier. Analog output signal level of 1V/100 mmHg is compatible with most pressure monitors and data acquisition systems. In line power supply adapts automatically to line voltages from 100 to 240 volts AC.
Proper citation: Millar: PCU-2000 Pressure Control Unit with Patient Isolation (RRID:SCR_018840) Copy
https://science-products.com/en/shop/491/23/data-aquisition/interfaces/micro1401-3
Unit records waveform data, digital event and marker information and can simultaneously generate waveform and digital outputs in real time for multi tasking experimental control.
Proper citation: CED: Micro1401-4 data acquisition unit (RRID:SCR_018846) Copy
https://rippleneuro.com/ripple-products/grapevine-processors/
Interface processor as 512 channel stimulation and recording electrophysiology tool. Designed to be safe for human subjects.
Proper citation: Ripple Neuro: Grapevine Neural Interface Processor (RRID:SCR_018897) Copy
https://www.leica-microsystems.com/products/light-microscopes/p/leica-dm4000-b/
Fluorescent microscope which supports fluorescence contrast techniques. This product is archived and has been replaced by the Leica DM4000 B LED.
Proper citation: Leica: DM4000 B Microscope (RRID:SCR_018895) Copy
https://millar.com/Research/PressureVolume-Loop-System/
Pressure volume loop system with seven available volume segments, range of gain settings, integrated internal ECG circuit and dual pressure amplifiers. System can be used in either large or small animal subjects, depending on which size catheter is used.
Proper citation: Millar: MPVS Ultra Pressure Volume Loop System (RRID:SCR_018894) Copy
https://www.beckman.com/flow-cytometry/instruments/moflo-astrios-eq
High speed flow cytometry sorter.
Proper citation: Beckman Coulter: Life Sciences MoFlo Astrios EQ Cell Sorter (RRID:SCR_018893) Copy
https://plexon.com/products/plexon-v-probe/
Linear electrode array used for intracranial electrophysiological recordings. V-Probe is multi-use, multi-site, linear electrode with recording sites positioned on side of sharpened, symmetric cone by Plexon Inc. Minimizes trauma to brain tissue upon insertion. Durable, highly customizable, and often used in acute research with medium to large animals.
Proper citation: Plexon: 16 channel V-Probe (RRID:SCR_018784) Copy
https://plexon.com/products/headstages/
Headstage that attaches to 16-channel linear electrode arrays by Plexon Inc. Digitizes analog voltage signals and outputs them to data acquisition systems.
Proper citation: Plexon: 16-channel digital headstage (RRID:SCR_018783) Copy
Axio Imager 2 resolves samples from tissue sections in pathology to brain specimens in neuroscience to multi dyed FISH specimens. Works with ZEN imaging software.
Proper citation: Zeiss: Axio Imager 2 (RRID:SCR_018876) Copy
Pulse generator that can hold 8 different pre-programmed paradigms all of which can use up to all 8 channels.
Proper citation: A.M.P.I.: Master 8 stimulator (RRID:SCR_018889) Copy
https://www.norlab.com/library/brochure/11566
Multi channel peristaltic pump for applications with different viscous or abrasive fluids. Allows for channel cartridges, from one to sixteen, to be changed while pump is running.
Proper citation: Gilson: Minipuls Evolution peristaltic pump (RRID:SCR_018955) Copy
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