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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Software library that contains functions that calculate various statistics of differential expression for microarray data, including t statistics, fold change, F statistics, SAM, moderated t and F statistics and B statistics. It also implements methodology (Differential Expression via Distance Summary) which selects differentially expressed genes by integrating and summarizing a set of statistics using a weighted distance approach.
Proper citation: DEDS (RRID:SCR_001339) Copy
https://bioconductor.org/packages//2.13/bioc/html/virtualArray.html
Software package that permits the user to combine raw data of different microarray platforms into one virtual array. It consists of several functions that act subsequently in a semi-automatic way. Doing as much of the data combination and letting the user concentrate on analyzing the resulting virtual array.
Proper citation: virtualArray (RRID:SCR_001361) Copy
http://www.bioconductor.org/packages/release/bioc/html/stepNorm.html
Software for stepwise normalization functions for cDNA microarray data.
Proper citation: stepNorm (RRID:SCR_001359) Copy
http://www.bioconductor.org/packages/release/bioc/html/rama.html
Software package for robust estimation of cDNA microarray intensities with replicates. It uses a Bayesian hierarchical model for the robust estimation. Outliers are modeled explicitly using a t-distribution, and the model also addresses classical issues such as design effects, normalization, transformation, and nonconstant variance.
Proper citation: RAMA (RRID:SCR_001358) Copy
http://www.bioconductor.org/packages/release/bioc/html/MANOR.html
Software packqge for importation, normalization, visualization, and quality control functions to correct identified sources of variability in array-CGH (Comparative genomic hybridization) experiments.
Proper citation: MANOR (RRID:SCR_001305) Copy
http://www.bioconductor.org/packages/release/bioc/html/dyebias.html
Software package using the GASSCO method for correcting for slide-dependent gene-specific dye bias.
Proper citation: dyebias (RRID:SCR_001308) Copy
http://www.bioconductor.org/packages/release/bioc/html/limmaGUI.html
Software package for a Graphical User Interface for the limma Microarray package.
Proper citation: limmaGUI (RRID:SCR_001306) Copy
http://www.bioconductor.org/packages/release/bioc/html/ffpe.html
Software to identify low-quality data using metrics developed for expression data derived from Formalin-Fixed, Paraffin-Embedded (FFPE) data. Also a function for making Concordance at the Top plots (CAT-plots).
Proper citation: ffpe (RRID:SCR_001307) Copy
http://www.bioconductor.org/packages/release/bioc/html/SNAGEE.html
Software package that uses signal-to-noise ratios (SNRs) as a proxy for quality of gene expression studies and samples. The SNRs can be calculated on any gene expression data set as long as gene IDs are available, no access to the raw data files is necessary. This allows to flag problematic studies and samples in any public data set.
Proper citation: SNAGEE (RRID:SCR_001301) Copy
http://www.bioconductor.org/packages/release/bioc/html/ACME.html
A set of tools for analysing tiling array ChIP/chip, DNAse hypersensitivity, or other experiments that result in regions of the genome showing enrichment. It does not rely on a specific array technology (although the array should be a tiling array), is very general (can be applied in experiments resulting in regions of enrichment), and is very insensitive to array noise or normalization methods. It is also very fast and can be applied on whole-genome tiling array experiments quite easily with enough memory.
Proper citation: ACME (RRID:SCR_001464) Copy
http://www.bioconductor.org/packages/release/bioc/html/CoGAPS.html
Software that infers biological processes which are active in individual gene sets from corresponding microarray measurements. It achieves this inference by combining a MCMC matrix decomposition algorithm (GAPS) with a novel statistic inferring activity on gene sets.
Proper citation: CoGAPS (RRID:SCR_001479) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowFP.html
A Bioconductor software package for fingerprint generation of flow cytometry data, used to facilitate the application of machine learning and datamining tools for flow cytometry.
Proper citation: flowFP (RRID:SCR_001537) Copy
http://www.bioconductor.org/packages/release/bioc/html/ArrayExpress.html
Software to access the ArrayExpress Repository at EBI and build Bioconductor data structures: ExpressionSet, AffyBatch, NChannelSet
Proper citation: ArrayExpress (R) (RRID:SCR_000120) Copy
http://www.bioconductor.org/packages/release/bioc/html/AffyRNADegradation.html
Software package that helps with the assessment and correction of RNA degradation effects in Affymetrix 3' expression arrays. The parameter d gives a robust and accurate measure of RNA integrity. The correction removes the probe positional bias, and thus improves comparability of samples that are affected by RNA degradation.
Proper citation: AffyRNADegradation (RRID:SCR_000118) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/VariantAnnotation.html
Software package to annotate variants, compute amino acid coding changes, and predict coding outcomes.
Proper citation: VariantAnnotation (RRID:SCR_000074) Copy
http://www.bioconductor.org/packages/release/bioc/html/timecourse.html
Software functions for data analysis and graphical displays for developmental microarray time course data.
Proper citation: timecourse (RRID:SCR_000077) Copy
http://www.bioconductor.org/packages/release/bioc/html/ncdfFlow.html
Software package that provides netCDF storage based methods and functions for manipulation of flow cytometry data.
Proper citation: ncdfFlow (RRID:SCR_000009) Copy
http://bioconductor.org/packages/release/bioc/html/CorMut.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16,2023. Software package for computing correlated mutations based on selection pressure. Three methods are provided for detecting correlated mutations, including conditional selection pressure, mutual information and Jaccard index. The computation consists of two steps: First, the positive selection sites are detected; second, the mutation correlations are computed among the positive selection sites. Note that the first step is optional. Meanwhile, CorMut facilitates the comparison of the correlated mutations between two conditions by the means of correlated mutation network.
Proper citation: CorMut (RRID:SCR_000053) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowBin.html
A software package to combine flow cytometry data that has been multiplexed into multiple tubes with common markers between them. It establishes common bins across tubes in terms of the common markers, then determines expression within each tube for each bin in terms of the tube-specific markers.
Proper citation: flowBin (RRID:SCR_000051) Copy
http://www.bioconductor.org/packages/release/bioc/html/metaSeq.html
Software package for meta-analysis of RNA-Seq count data in multiple studies. The probabilities by one-sided NOISeq are combined by Fisher's method or Stouffer's method.
Proper citation: metaSeq (RRID:SCR_000056) Copy
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