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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
PGS
 
Resource Report
Resource Website
PGS (RRID:SCR_000475) software resource Software tool for association study of high-dimensional microRNA expression data with repeated measures. The penalized regression model incorporates a grid search method for analyzing associations of high-dimensional microRNA expression data with repeated measures. standalone software, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24947752 Free, Available for download, Freely available biotools:pgs, OMICS_04651 https://bio.tools/pgs SCR_000475 SciCrunch Registry PGS: Penalized GEE with Grid Search, Penalized GEE with Grid Search 2026-10-24 12:44:17 0
Human Disease Ontology
 
Resource Report
Resource Website
1+ mentions
Human Disease Ontology (RRID:SCR_000476) DO controlled vocabulary, data or information resource, database, ontology Comprehensive hierarchical controlled vocabulary for human disease representation.Open source ontology for integration of biomedical data associated with human disease. Disease Ontology database represents comprehensive knowledge base of inherited, developmental and acquired human diseases. obo, pathological, organismal, cellular, disease, biomedical, health, neurologic disease, neurological disorder, phenotype, bio.tools, is used by: DOAF
is listed by: BioPortal
is listed by: OBO
is listed by: bio.tools
is listed by: Debian
is related to: PharmGKB Ontology
is related to: GWASdb
is related to: NUgene Project
is related to: FunDO
is related to: Neurocarta
has parent organization: University of Maryland School of Medicine; Maryland; USA
NHGRI U24 HG012557 PMID:22080554 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-35926, nlx_157432, SCR_003491, biotools:disease_ontology http://disease-ontology.org/, https://bio.tools/disease_ontology, http://purl.obolibrary.org/obo/doid.obo, http://do-wiki.nubic.northwestern.edu/index.php/Main_Page SCR_000476 SciCrunch Registry Human Disease Ontology Knowledgebase, Disease Ontology 2026-10-24 12:44:17 5
ContEst
 
Resource Report
Resource Website
1+ mentions
ContEst (RRID:SCR_000595) ContEst software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. A software tool (and method) for estimating the amount of cross-sample contamination in next generation sequencing data. java, contamination, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Broad Institute
PMID:21803805 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01038, biotools:contest https://bio.tools/contest SCR_000595 SciCrunch Registry 2026-10-24 12:44:20 6
MPscan
 
Resource Report
Resource Website
MPscan (RRID:SCR_000587) MPscan data access protocol, software resource, web service Web tool for index free mapping of multiple short reads on a genome. linux, macos, next-generation sequencing, genome, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: ATGC: Montpellier bioinformatics platform
Free, Available for download, Freely available biotools:mpscan, OMICS_00670 https://bio.tools/mpscan SCR_000587 SciCrunch Registry MPscan: index free mapping of multiple short reads on a genome 2026-10-24 12:44:20 0
Mfuzz
 
Resource Report
Resource Website
10+ mentions
Mfuzz (RRID:SCR_000523) software resource Software package for noise-robust soft clustering of gene expression time-series data (including a graphical user interface)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. r, time series, gene expression, clustering, microarray, preprocessing, time course, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:18084642 THIS RESOURCE IS NO LONGER IN SERVICE biotools:mfuzz, OMICS_02012 https://bio.tools/mfuzz http://itb.biologie.hu-berlin.de/~futschik/software/R/Mfuzz/ SCR_000523 SciCrunch Registry Mfuzz - Soft clustering of time series gene expression data 2026-10-24 12:44:15 16
Pindel
 
Resource Report
Resource Website
10+ mentions
Pindel (RRID:SCR_000560) Pindel software resource Software to detect breakpoints of large deletions, medium sized insertions, inversions, tandem duplications and other structural variants at single-based resolution from next-gen sequence data. It uses a pattern growth approach to identify the breakpoints of these variants from paired-end short reads., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. deletion, insertion, nucleotide, genome, read, inversion, tandem duplication, structural variant, next-generation sequencing, pattern growth, indel, breakpoint, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA
works with: cgpPindel
PMID:19561018 THIS RESOURCE IS NO LONGER IN SERVICE biotools:pindel, OMICS_00321 https://bio.tools/pindel SCR_000560 SciCrunch Registry 2026-10-24 12:44:19 25
FPSAC
 
Resource Report
Resource Website
1+ mentions
FPSAC (RRID:SCR_000555) FPSAC software resource Sogftware for fast Phylogenetic Scaffolding of Ancient Contigs. genome, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Simon Fraser University; British Columbia; Canada
PMID:24068034 biotools:fpsac, OMICS_00041 https://bio.tools/fpsac SCR_000555 SciCrunch Registry Fast Phylogenetic Scaffolding of Ancient Contigs (FPSAC) and application to the medieval Black Death agent, Fast Phylogenetic Scaffolding of Ancient Contigs, FPSAC: fast phylogenetic scaffolding of ancient contigs 2026-10-24 12:44:18 1
POPBAM
 
Resource Report
Resource Website
POPBAM (RRID:SCR_000464) POPBAM data analysis software, data processing software, software application, software resource A tool to perform evolutionary or population-based analyses of next-generation sequencing data. POPBAM takes a BAM file as its input and can compute many widely used evolutionary genetics measures in sliding windows across a genome. next-generation sequencing, evolution, population, bam, genome, evolutionary genetics, c++, short read, sequence alignment, sliding window, command-line, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: University of Rochester; New York; USA
PMID:24027417 Free, Available for download, Freely available biotools:popbam, OMICS_01559 https://bio.tools/popbam http://popbam.sourceforge.net/ SCR_000464 SciCrunch Registry 2026-10-24 12:44:14 0
drFAST
 
Resource Report
Resource Website
1+ mentions
drFAST (RRID:SCR_000586) drFAST software resource A software which maps di-base reads (SOLiD color space reads) to reference genome assemblies in a fast and memory-efficient manner. di-base, solid color space, genome assemblies, memory-efficient, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: SourceForge
PMID:21586516 Free, Available for download, Freely available biotools:drfast, OMICS_00661 https://bio.tools/drfast SCR_000586 SciCrunch Registry di-base read Fast Alignment Search Tool, drFAST: di-base read Fast Alignment Search Tool 2026-10-24 12:44:19 1
Genome BioInformatics Research Lab - gff2ps
 
Resource Report
Resource Website
1+ mentions
Genome BioInformatics Research Lab - gff2ps (RRID:SCR_000462) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software program for visualizing annotations of genomic sequences. The program has features such as the ability to create comprehensive plots, customizable parameters, and flexibility in file format. genome, sequence, visualization, parameters, bioinformatics, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:11099262
DOI:10.1093/bioinformatics/16.8.743
Free, Available for download, Freely available OMICS_17140, biotools:gff2ps, nif-0000-30611 https://bio.tools/gff2ps, https://sources.debian.org/src/gff2ps/ SCR_000462 SciCrunch Registry gff2ps 2026-10-24 12:44:16 1
Rdisop
 
Resource Report
Resource Website
Rdisop (RRID:SCR_000453) software resource Software for identification of metabolites using high precision mass spectrometry. MS Peaks are used to derive a ranked list of sum formulae, alternatively for a given sum formula the theoretical isotope distribution can be calculated to search in MS peak lists. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02416, biotools:rdisop https://github.com/sneumann/Rdisop, https://bio.tools/rdisop SCR_000453 SciCrunch Registry Rdisop - Decomposition of Isotopic Patterns, Rdisop: Decomposition of Isotopic Patterns, Decomposition of Isotopic Patterns 2026-10-24 12:44:16 0
pFind Studio: pLink
 
Resource Report
Resource Website
10+ mentions
pFind Studio: pLink (RRID:SCR_000084) pLink software resource Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. mass spectrometry, proteomics, pFind Studio, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chinese Academy of Sciences; Beijing; China
PMID:22772728 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02404, biotools:pLink-2 https://github.com/pFindStudio/pLink3/releases http://pfind.ict.ac.cn/software/pLink/index.html SCR_000084 SciCrunch Registry , pLink, pLink (pFind Studio), pLink2 2026-10-24 12:44:07 15
GEOquery
 
Resource Report
Resource Website
10+ mentions
GEOquery (RRID:SCR_000146) GEOquery software resource Software that establishes a bridge between GEO and BioConductor. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Expression Omnibus
is related to: GEO2R
has parent organization: Bioconductor
has parent organization: National Institutes of Health
PMID:17496320 Free, Available for download, Freely available biotools:geoquery, OMICS_01972 https://bio.tools/geoquery, https://sources.debian.org/src/r-bioc-geoquery/ SCR_000146 SciCrunch Registry GEOquery - Get data from NCBI Gene Expression Omnibus (GEO) 2026-10-24 12:44:08 20
GUARDD
 
Resource Report
Resource Website
GUARDD (RRID:SCR_000040) software resource MATLAB software designed to organize, automate, and enhance the analytical procedures which operate on CPMG RD NMR data. standalone software, matlab, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:22160811 Free, Available for download, Freely available biotools:guardd, OMICS_04020 https://bio.tools/guardd SCR_000040 SciCrunch Registry Graphical User-friendly Analysis of Relaxation Dispersion Data 2026-10-24 12:44:05 0
GASV
 
Resource Report
Resource Website
1+ mentions
GASV (RRID:SCR_000061) GASV data analysis software, data processing software, software application, software resource Software tool for identifying structural variants (SVs) from paired-end sequencing data.GASV distribution includes three components that are typically run in succession: the BAM file of unique paired-read mappings is processed; structural variants are identified by clustering discordant fragments; and a probabilistic algorithm improves the specificity of GASV predictions. paired-end sequencing data, structural variant, probabilistic algorithm, discordant fragment, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GASVPro
has parent organization: Brown University; Rhode Island; USA
ADVANCE Program at Brown University ;
Burroughs Wellcome Fund ;
Department of Defense Breast Cancer Research ;
NSF 0548311
PMID:19477992 Free, Available for download, Freely available biotools:gasv, OMICS_01352 http://compbio.cs.brown.edu/projects/gasv/, https://bio.tools/gasv SCR_000061 SciCrunch Registry Geometric Analysis of Structural Variants 2026-10-24 12:44:06 4
FACS
 
Resource Report
Resource Website
1+ mentions
FACS (RRID:SCR_000055) FACS software resource Software for classification of Sequences using Bloom filters that can accurately and rapidly align sequences to a reference sequence. unix/linux, sequence, bio.tools is listed by: OMICtools
is listed by: GitHub
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: SciLifeLab
PMID:20472541 Free, Available for download, Freely available OMICS_02147, biotools:facs https://bio.tools/facs SCR_000055 SciCrunch Registry Fast and Accurate Classification of Sequences 2026-10-24 12:44:06 6
CD-HIT
 
Resource Report
Resource Website
1000+ mentions
CD-HIT (RRID:SCR_007105) CD-HIT data processing software, software application, software resource, source code THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software program for clustering biological sequences with many applications in various fields such as making non-redundant databases, finding duplicates, identifying protein families, filtering sequence errors and improving sequence assembly etc. It is very fast and can handle extremely large databases. CD-HIT helps to significantly reduce the computational and manual efforts in many sequence analysis tasks and aids in understanding the data structure and correct the bias within a dataset. The CD-HIT package has CD-HIT, CD-HIT-2D, CD-HIT-EST, CD-HIT-EST-2D, CD-HIT-454, CD-HIT-PARA, PSI-CD-HIT, CD-HIT-OTU and over a dozen scripts. * CD-HIT (CD-HIT-EST) clusters similar proteins (DNAs) into clusters that meet a user-defined similarity threshold. * CD-HIT-2D (CD-HIT-EST-2D) compares 2 datasets and identifies the sequences in db2 that are similar to db1 above a threshold. * CD-HIT-454 identifies natural and artificial duplicates from pyrosequencing reads. * CD-HIT-OTU cluster rRNA tags into OTUs The usage of other programs and scripts can be found in CD-HIT user''s guide. CD-HIT was originally developed by Dr. Weizhong Li at Dr. Adam Godzik''s Lab at the Burnham Institute (now Sanford-Burnham Medical Research Institute)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. cluster, protein, sequence, classification, domain, analysis, nucleotide sequence, dna, protein sequence, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: University of California at San Diego; California; USA
has parent organization: Google Code
is parent organization of: CD-HIT-OTU
NCRR 1R01RR025030 PMID:20053844
PMID:16731699
DOI:10.1093/bioinformatics/btl158
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_05157, biotools:cd-hit, nif-0000-30240 http://cd-hit.org, https://code.google.com/p/cdhit/, https://bio.tools/cd-hit, https://sources.debian.org/src/cd-hit/ http://bioinformatics.ljcrf.edu/cd-hi/
SCR_007105 SciCrunch Registry CD-HIT Program 2026-10-24 12:45:57 3223
Expression Database in 4D
 
Resource Report
Resource Website
1+ mentions
Expression Database in 4D (RRID:SCR_007066) 4DXpress data or information resource, data repository, database, service resource, storage service resource This database provides a platform to query and compare gene expression data during the development of the major model animals (zebrafish, drosophila, medaka, mouse). The name 4DXpress stands for expression database in 4D. The 4D (four dimensions) of 4DXpress can be interpreted either as: 3 spatial dimensions plus time, or as 1. species 2. gene 3. developmental stage 4. anatomical structure. The major focus of this database lies in cross species comparison. The high resolution expression data was acquired through whole mount in situ hybridsation-, antibody- or transgenic experiments. Data was integrated from several species specific expression pattern databases, such as ZFIN, BDGP, GXD, MEPD as well as directly submitted by researchers of the participating groups at EMBL. The 4DXpress database is a project within the Centre for Computational Biology at EMBL. It is developed by Yannick Haudry, Thorsten Henrich and Ivica Letunic and coordinated by Thorsten Henrich. Hugo Berube is developing the 4D ArrayExpress Data Warehouse at EBI for integrating in situ data with microarray data. genes, anatomical structures, developmental stage, microarray data, species, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
European Molecular Biology Laboratory; Heidelberg; Germany PMID:17916571 nif-0000-02524, biotools:4dxpress https://bio.tools/4dxpress SCR_007066 SciCrunch Registry 4DXpress Database 2026-10-24 12:45:56 1
Chromosome 7 Annotation Project
 
Resource Report
Resource Website
10+ mentions
Chromosome 7 Annotation Project (RRID:SCR_007134) Chromosome 7 Annotation Project data or information resource, data repository, database, service resource, storage service resource Database containing the DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented; the most up to date collation of sequence, gene, and other annotations from all databases (eg. Celera published, NCBI, Ensembl, RIKEN, UCSC) as well as unpublished data. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. The objective of this project is to generate a comprehensive description of human chromosome 7 to facilitate biological discovery, disease gene research and medical genetic applications. There are over 360 disease-associated genes or loci on chromosome 7. A major challenge ahead will be to represent chromosome alterations, variants, and polymorphisms and their related phenotypes (or lack thereof), in an accessible way. In addition to being a primary data source, this site serves as a weighing station for testing community ideas and information to produce highly curated data to be submitted to other databases such as NCBI, Ensembl, and UCSC. Therefore, any useful data submitted will be curated and shown in this database. All Chromosome 7 genomic clones (cosmids, BACs, YACs) listed in GBrowser and in other data tables are freely distributed. duplication, gene expression, family, fish, gene, gene annotation, genome, breakpoint, chromosome, chromosome 7, clinical, deletion, disease, dna sequence, human, insertion, inversion, polymorphism, rearrangement, segmental duplication, snp, translocation, annotation, data analysis service, blat, cosmid, bac, yac, biomaterial supply resource, malignant, non malignant, bio.tools is listed by: One Mind Biospecimen Bank Listing
is listed by: Debian
is listed by: bio.tools
PMID:12690205 Free, (Genomic clones) nif-0000-03550, biotools:chr7, r3d100012136 https://bio.tools/chr7, https://doi.org/10.17616/R3VP9V SCR_007134 SciCrunch Registry The Chromosome 7 Annotation Project, Chromosome 7 Annotation Project 2026-10-24 12:45:53 13
Biological General Repository for Interaction Datasets (BioGRID)
 
Resource Report
Resource Website
1000+ mentions
Biological General Repository for Interaction Datasets (BioGRID) (RRID:SCR_007393) BioGRID data or information resource, database Curated protein-protein and genetic interaction repository of raw protein and genetic interactions from major model organism species, with data compiled through comprehensive curation efforts. budding yeast, fission yeast, protein, gene, protein interaction, genetic interaction, model organism, interaction, dataset, gene annotation, phenotype, orthologous interaction, yeast, cellular interaction network, physical interaction, protein-peptide, protein-rna, protein-protein interaction, genetics, publication, raw protein, genetic interaction, web service, pathway, network, biology, gene mapping, statistics, bio.tools, FASEB list is used by: NIF Data Federation
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: OMICtools
is listed by: DataCite
is listed by: NIH Data Sharing Repositories
is listed by: bio.tools
is listed by: Debian
is related to: TissueNet - The Database of Human Tissue Protein-Protein Interactions
is related to: Pathway Commons
is related to: Cytoscape
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: FlyMine
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Integrated Molecular Interaction Database
is related to: PSICQUIC Registry
is related to: PSI-MI
is related to: NIH Data Sharing Repositories
is related to: Agile Protein Interactomes DataServer
is related to: Integrated Manually Extracted Annotation
has parent organization: Princeton University; New Jersey; USA
has parent organization: University of Edinburgh; Scotland; United Kingdom
has parent organization: University of Montreal; Quebec; Canada
works with: IMEx - The International Molecular Exchange Consortium
BBSRC ;
Canadian Institutes of Health Research ;
NCRR R01 RR024031;
NHGRI HG02223;
NIH Office of the Director R24 OD011194
PMID:23203989
PMID:21071413
PMID:16381927
PMID:12620108
Free, Freely available nif-0000-00432, r3d100010350, OMICS_01901, biotools:the_grid https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources, https://bio.tools/the_grid, https://doi.org/10.17616/R34C7G SCR_007393 SciCrunch Registry , BioGRID, Biological General Repository for Interaction Datasets 2026-10-24 12:45:57 2824

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