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http://harvard.eagle-i.net/i/0000012c-7441-2a90-c437-ff0b80000000

Core facility that provides the following services: Tissue trimming, cassetting, processing, and embedding, Cutting and staining of paraffin-embedded and cryostat sections, Immunohistochemistry for both routine and novel markers, In situ hybridization, using chromogenic or radioactive detection methods, Laser capture microdissection.

Tissue analysis is critical to validation and evaluation of animal models of human cancer, and human cancer tissues serve as the operating system for translational research. The facility supports a wide spectrum of cancer-relevant research, from basic studies on pathogenic mechanisms in cancer to translational research focused on the development of new tests for biomarkers that stratify patients and direct therapy. The Specialized Histopathology (SHP) Core, was created in 2005 by consolidating five histopathology cores into a single unit with two performance sites: Longwood, Directed by Jon Aster and based at the Brigham and Women?s Hospital and MGH, Directed by Anat Stemmer-Rachamimov and based at Massachusetts General Hospital East in Charlestown. The SHP Core provides professional and technical research pathology services to DF/HCC investigators working in diverse organisms (e.g., rodents, fish, and monkeys) or human tissues. The Core also assists in experimental design and the development and interpretation of tests and their results. As of July 2012, the Longwood site offers CLIA Certified services.

Proper citation: DF/HCC Specialized Histopathology Services Core (RRID:SCR_000872) Copy   

•   Source: SciCrunch Registry

http://wyss.harvard.edu/viewpage/594/

A core facility with access to imaging equipment and analysis software such as wide-field light microscopy, Total Internal Reflection Fluorescence microscopy (TIRF), confocal microscopy, Atomic Force Microscopy (AFM), Transmission Electron Microscopy (TEM), small animal imaging, spectroscopy, and flow cytometry.

Proper citation: Wyss Institute Imaging Core (RRID:SCR_000898) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013c-40b7-7a2a-f162-a2b280000000

Core facility that provides the following services: PET/SPECT/CT image analysis.

Proper citation: Penn Small Animal Imaging Facility: PET/SPECT/CT Sub-Core (RRID:SCR_000890) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-00bd-5152-3984-bcfb80000000

A research laboratory and facility which supports research on environmental toxicology at Jackson State University.

Proper citation: JSU Environmental Toxicology Core Lab (RRID:SCR_000884) Copy   

•   Source: SciCrunch Registry

http://www.cma.mgh.harvard.edu/

A center dedicated to developing and applying morphometric methods to biomedical imaging data such as high-resolution MRI. The lab uses automated and semi-automated software such that MRI brain images are segmented into anatomical regions of interest. Projects in both basic and applied brain research include research on strokes and tumors; medical image processing research includes shape analysis of anatomical brain regions and measurement and analysis of brain volumes.

Proper citation: MGH Center for Morphometric Analysis (RRID:SCR_000885) Copy   

•   Source: SciCrunch Registry

http://biology.hunter.cuny.edu/index.php?option=com_content&view=article&id=138&Itemid=117

Facility which provides instruments and instrument resources for analyzing DNA, RNA, protein, and radio-labeled substances.

Proper citation: Hunter Genomic Facility (RRID:SCR_001983) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250e-1301-43fb-601a80000000

THIS RESOURCE IS NO LONGER IN SERVICE, documented June 26, 2017. Lab that provides resources for researchers such as image analysis and access to confocal microscopes.

Proper citation: UPR Analysis Resource Center Confocal Microscopy Core Laboratory (RRID:SCR_002330) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-3517-ac53-550e-f59280000000

Core facility that provides metals analytical capabilities to biomedical and non-biomedical researchers and serves as a source for study design consultation and sample QA/QC requirements. The transport, fate, exposure, and toxic effects of heavy metals is a primary focus of research at the Center. It operates as a modified fee-for-service laboratory. Researchers have the option of having the samples run by the Service staff, or of receiving instruction (for themselves or a doctoral or post doctoral trainee) on how to operate the analytical equipment and analyze their own samples. Both options have associated fees and, as with other services, facility access funds can be requested internal or external services when individual grant support is not yet available.

Proper citation: HSPH Trace Metals Laboratory (RRID:SCR_002819) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-e19e-59a0-d807-77a880000000

Microscopists at Weld Hill will find a range of tools from the simple hand lens to the confocal microscope for 3-D reconstructions.

Proper citation: Arnold Arboretum of Harvard University: Weld Hill Microscopy Lab (RRID:SCR_004485) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c61a-a13e-b341-4bb480000000

Core facility that provides the following services: Energy Expenditure Assessment, Body Composition Assessment, Physical Activity Assessment. This component of the core utilizes existing institutional resources for measurement of energy balance and provides personnel support that permit assessment of research in energy balance and nutrition assessment.

Proper citation: Vanderbilt Energy Balance Core Laboratory (RRID:SCR_006665) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012a-24fd-6cc0-d8a1-249280000000

Core facility that provides the following services: 7500 fast Q-PCR service, MALDI MS service, Agilent 2100 bioanalyzer service, NanoDrop 1000 service.

Proper citation: Dartmouth Shared Instruments Core Laboratory (RRID:SCR_006415) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-60c2-395c-c437-ff0b80000000

Core facility that provides the following services: Cell immortalization through retroviral or lentiviral vectors service, Microscopy training, User-based microscopy service.

Proper citation: BWH Cell Culture and Microscopy Core (RRID:SCR_005562) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-56f2-62b7-2162-17a280000000

Core facility that provides the following services: Ultrasound/sonography access service. Ultrasound, which is also known as sonography, is a painless, non-invasive imaging technique that lets us look inside your child''s body without the use of radiation. It uses high-frequency sound waves to create pictures of organs, bones, tissues and blood vessels.

Proper citation: CHB Ultrasound (RRID:SCR_009608) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000013c-fd63-dfbb-ea7a-a3a980000000

Core facility that provides the following services: Circulating Tumor Cell analysis, Circulating Tumor Cell Purification. The Circulating Tumor Cell Core Facility uses immunomagnetic technology developed by Veridex, LLC (Raritan, NJ) to isolate rare tumor cells from whole blood. Isolated tumor cells can then be counted or used for downstream analysis such as molecular studies or flow cytometry.

Proper citation: BWH Circulating Tumor Cell Core (RRID:SCR_008258) Copy   

•   Source: SciCrunch Registry

http://cdrewu.eagle-i.net/i/00000136-0961-ccb9-1a88-e81c80000000

Core facility that provides the following services: Establishing primary cell line from human tissues, HLA genotyping, Immunohistochemical staining, Immortalization of primary cell lines, Testing RNA quality for mRNA array analysis. Molecular and Translational research in oncology

Proper citation: CDU Cancer Research and Training Core Facility (RRID:SCR_009580) Copy   

•   Source: SciCrunch Registry

http://cau.eagle-i.net/i/00000136-59de-ff9a-982a-4eef80000000

The mission of the CCRTD Research Support Core Facilities is to provide the scientists of CCRTD, Clark Atlanta University, and Atlanta University Center with access to modern technology, resources, and instruments essential for cutting-edge research in molecular biology, genomics, proteomics, cell biology, and biological imaging.

Proper citation: CAU CCRTD-Histology Core (RRID:SCR_009412) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000134-aa06-dbc4-bf4c-ca4080000000

Core facility that provides the following services: Flow cytometry equipment and software access, FACS machine training, FACS data analysis, FACS analysis and population isolation, FACS assay consultation. The goals of this Core Facility are to provide flow cytometry services for Howard University?s research investigators, and develop new applications.

Proper citation: Howard Flow Cytometry Core (RRID:SCR_008506) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c4-d136-db6e-7a3f80000000

Core facility that provides the following services: In Vivo Magnetic Resonance Imaging (MRI), Quantitative Image Analysis: Standard Uptake Value (SUV), 3D Volume Measurements, Animal Handling Techniques: Blood Collection, Injections (IV, IP), Oral Gavage, Tumor Inoculation, Transcardiac Perfusion, etc., Whole-body and Tissue Cryosectioning, Ex Vivo Tissue Radioactivity Measurement.

Our goal is to provide state-of-the-art small animal imaging services to researchers in the Longwood Medical Area of Harvard Medical School. These services include multi-modality imaging, advanced data analysis, image fusion resources, and a satellite animal facility for longitudinal studies. A detailed description of our instruments and services are provided on our website, and we welcome questions and comments.

Proper citation: BIDMC Longwood Small Animal Imaging Core Facility (RRID:SCR_009670) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2518-fb6c-5617-794280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27, 2023. Core provides services: RT PCR service, Gene expression profiling service, Proteomics analysis service, Bioinformatics and Systems Biology analyses, Next Generation Sequencing Service, Affymetrix Human and Mouse Gene 2.0 ST Arrays and 2.1 ST Arrayplates. Core proteomics facility for the Dana-Farber/Harvard Cancer Center. Workflows and algorithms for analysis of next-generation sequencing data including RNA-Seq, ChIP-Seq, Epigenetics-Seq and DNA seq, Comprehensive workflow for analysis of Microbiome sequencing data, Integrated systems biology analysis of transcriptome, miRNA, epigenome, metabolomics and proteomics data. Pipelines: MALDI Tissue imaging and targeted quantitative proteomics.

Proper citation: Beth Israel Deaconess Medical Center Genomics Proteomics Bioinformatics and Systems Biology Center (RRID:SCR_009668) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-6cd0-f03d-55da-381e80000000

Core facility that provides the following services: Cell sorting service.

The Department of Pathology Flow Cytometry Facility provides flow cytometric analysis and cell sorting services to investigators in the Harvard Medical School and in the Harvard affiliated hospitals and institutions. The facility currently has a FACSCalibur for assisted as well as unassisted flow cytometric acquisition and analysis, and a FACSAria for cell sorting (performed by an expert technician).

Proper citation: HMS Flow Cytometry Facility (RRID:SCR_009666) Copy   

•   Source: SciCrunch Registry