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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PlantNATsDB - Plant Natural Antisense Transcripts DataBase
 
Resource Report
Resource Website
1+ mentions
PlantNATsDB - Plant Natural Antisense Transcripts DataBase (RRID:SCR_013278) PlantNATsDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Natural Antisense Transcripts (NATs), a kind of regulatory RNAs, occur prevalently in plant genomes and play significant roles in physiological and/or pathological processes. PlantNATsDB (Plant Natural Antisense Transcripts DataBase) is a platform for annotating and discovering NATs by integrating various data sources involving approximately 2 million NAT pairs in 69 plant species. PlantNATsDB also provides an integrative, interactive and information-rich web graphical interface to display multidimensional data, and facilitate plant research community and the discovery of functional NATs. GO annotation and high-throughput small RNA sequencing data currently available were integrated to investigate the biological function of NATs. A ''''Gene Set Analysis'''' module based on GO annotation was designed to dig out the statistical significantly overrepresented GO categories from the specific NAT network. PlantNATsDB is currently the most comprehensive resource of NATs in the plant kingdom, which can serve as a reference database to investigate the regulatory function of NATs. natural antisense transcript, annotation, high-throughput, small rna sequencing, function, regulatory function, predict, sequence, small rna, blast, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Gene Expression Omnibus
has parent organization: Zhejiang University; Zhejiang; China
National Natural Sciences Foundation of China 30971743;
National Natural Sciences Foundation of China 31050110121;
National Natural Sciences Foundation of China 31071659;
Ministry of Science and Technology of China 2009DFA32030;
Program for New Century Excellent Talents in University of China NCET-07-0740;
Huazhong Agricultural University Scientific and Technological Self-innovation Foundation 2010SC07
PMID:22058132 Free nlx_151492, biotools:plantnatsdb https://bio.tools/plantnatsdb SCR_013278 Plant Natural Antisense Transcripts DataBase 2026-09-12 12:58:01 9
CEM
 
Resource Report
Resource Website
1+ mentions
CEM (RRID:SCR_013241) CEM software resource An algorithm to assemble transcripts and estimate their expression levels from RNA-Seq reads. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at Riverside; California; USA
OMICS_01271, biotools:cem https://bio.tools/cem SCR_013241 CEM: Transcriptome Assembly and Isoform Expression Level Estimation from Biased RNA-Seq Reads 2026-09-12 12:58:00 1
BEADS
 
Resource Report
Resource Website
10+ mentions
BEADS (RRID:SCR_013229) BEADS software resource Software for a normalization scheme that corrects nucleotide composition bias, mappability variations and differential local DNA structural effects in deep sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: University of Cambridge; Cambridge; United Kingdom
PMID:21646344 OMICS_00466, biotools:beads https://bio.tools/beads SCR_013229 BEADS: Bias Elimination Algorithm for Deep Sequencing, Bias Elimination Algorithm for Deep Sequencing 2026-09-12 12:58:00 38
Trans-ABySS
 
Resource Report
Resource Website
50+ mentions
Trans-ABySS (RRID:SCR_013322) Trans-ABySS software resource A software pipeline for analyzing ABySS-assembled contigs from shotgun transcriptome data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
OMICS_01326, biotools:trans-abyss https://bio.tools/trans-abyss/ SCR_013322 2026-09-12 12:58:02 72
Probalign
 
Resource Report
Resource Website
10+ mentions
Probalign (RRID:SCR_013332) Probalign alignment software, data processing software, image analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software that uses partition function posterior probability estimates to compute maximum expected accuracy multiple sequence alignments. Computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities.Produces accurate alignments on long and heterogeneous length datasets containing protein repeats. is used by: eProbalign
is listed by: OMICtools
is listed by: Debian
has parent organization: New Jersey Institute of Technology; New Jersey; USA
PMID:16954142
DOI:10.1093/bioinformatics/btl472
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00985 https://sources.debian.org/src/probalign/ SCR_013332 Probalign: multiple sequence alignment using partition function posterior probabilities 2026-09-12 12:58:02 16
Dali Server
 
Resource Report
Resource Website
500+ mentions
Dali Server (RRID:SCR_013433) analysis service resource, data analysis service, production service resource, service resource, software resource Network service for comparing protein structures in 3D. You submit the coordinates of a query protein structure and Dali compares them against those in the Protein Data Bank (PDB). You receive an email notification when the search has finished. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing sequences. Requests can also be submitted by e-mail to dali-server at helsinki dot fi. The body of the e-mail message must contain atomic coordinates in PDB format. If you want to know the structural neighbours of a protein already in the Protein Data Bank (PDB), you can find them in the Dali Database. If you want to superimpose two particular structures, you can do it in the pairwise DaliLite server. Academic users may download the DaliLite program for local use. Protein structure comparison server, protein structure, comparison server, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: University of Helsinki; Helsinki; Finland
PMID:20457744 Free, Freely available biotools:dali https://bio.tools/dali SCR_013433 Dali 2026-09-12 12:58:03 534
ENIGMA
 
Resource Report
Resource Website
100+ mentions
ENIGMA (RRID:SCR_013400) data analysis software, data processing software, software application, software resource A software tool to extract gene expression modules from perturbational microarray data, based on the use of combinatorial statistics and graph-based clustering. The modules are further characterized by incorporating other data types, e.g. GO annotation, protein interactions and transcription factor binding information, and by suggesting regulators that might have an effect on the expression of (some of) the genes in the module. Version : ENIGMA 1.1 used GO annotation version : Aug 29th 2007 genome, gene, genetic software, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
is parent organization of: ENIGMA-DTI Pipeline
PMID:18402676 biotools:enigma, nlx_144365 https://bio.tools/enigma SCR_013400 2026-09-12 12:58:02 133
Pairwise Conservation Scores - An Algorithm to Identify Conserved K-mers
 
Resource Report
Resource Website
1+ mentions
Pairwise Conservation Scores - An Algorithm to Identify Conserved K-mers (RRID:SCR_013409) PCS software resource A stand-alone package to identify and analyze conserved k-mers in pairwise alignment. This program shows high performance for identifying miRNA seed binding sites in 3''-UTRs. perl, perl script, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Tsinghua University; Beijing; China
biotools:pcs, nlx_33020 https://bio.tools/pcs http://bioinfo.au.tsinghua.edu.cn/member/~gujin/pcs/ SCR_013409 Pairwise Conservation Scores 2026-09-12 12:58:03 3
TreeView
 
Resource Report
Resource Website
1000+ mentions
TreeView (RRID:SCR_013503) TreeView software resource Software to graphically browse results of clustering and other analyses from Cluster. is listed by: OMICtools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of California at Berkeley; Berkeley; USA
DOI:10.1093/bioinformatics/bth349 OMICS_01574 https://sources.debian.org/src/treeview/ SCR_013503 2026-09-12 12:58:03 2754
CNV-seq
 
Resource Report
Resource Website
100+ mentions
CNV-seq (RRID:SCR_013357) CNV-seq software resource A method for detecting DNA copy number variation (CNV) using high-throughput sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:cnv-seq, OMICS_00339 https://bio.tools/cnv-seq SCR_013357 2026-09-12 12:58:02 167
COPASI
 
Resource Report
Resource Website
100+ mentions
COPASI (RRID:SCR_014260) COPASI data analysis software, data processing software, simulation software, software application, software resource, standalone software Software application for simulation and analysis of biochemical network models and their dynamics. COPASI supports models in the SBML standard and can simulate their behavior using ODEs or Gillespies stochastic simulation algorithm. Arbitrary discrete events can be included in such simulations. Models in COPASI are based on reactions that convert a set of species into another set of species. Simulation can be performed either with stochastic kinetics or with differential equations. COPASI also includes various methods of analysis and data visualization. standalone software, simulation software, data analysis, biochemical system simulator, biochemical network model, biochemical network dynamics, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1093/bioinformatics/btl485 Free, Available for download, Acknowledgement requested biotools:copasi https://bio.tools/copasi SCR_014260 COPASI: Biochemical System Simulator 2026-09-12 12:58:14 445
CYANA
 
Resource Report
Resource Website
100+ mentions
CYANA (RRID:SCR_014229) data analysis software, data processing software, software application, software resource Software for automated structure calculation of biological macromolecules on basis of conformational constraints from nuclear magnetic resonance. Program for automated NMR protein structure calculation. CYANA requires a sufficient list of assigned chemical shifts and lists of cross-peak positions and columns from 2D, 3D, or4D NOESY spectra in order to calculate the assignment of the NOESY cross-peaks and the 3D structure of the protein in solution. protein structure, nmr, noesy, 3d structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Goethe University Frankfurt am Main; Hessen; Germany
has parent organization: RIKEN
PMID:15318003
PMID:25801209
Available to the academic community, Available to commercial user, Pay for license SCR_021949, biotools:cyana http://www.las.jp/english/products/cyana.html, https://bio.tools/cyana, https://dbpedia.org/page/CYANA_(software) SCR_014229 2026-09-12 12:58:14 428
Coot
 
Resource Report
Resource Website
10000+ mentions
Coot (RRID:SCR_014222) COOT data or information resource, model, simulation software, software application, software resource, software toolkit Software for macromolecular model building, model completion and validation, and protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, rigid-body fitting, ligand search, Ramachandran plots, non-crystallographic symmetry and more. Source code is available. software toolkit, simulation software, model manipulation, protein modeling, bio.tools is used by: PDB-REDO
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MolProbity
has parent organization: MRC Laboratory of Molecular Biology
PMID:15572765 Available for download, Acknowledgement requested biotools:coot http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Coot, https://bio.tools/coot SCR_014222 Crystallographic Object-Oriented Toolkit 2026-09-12 12:58:14 15682
SHELX
 
Resource Report
Resource Website
500+ mentions
SHELX (RRID:SCR_014220) data processing software, image analysis software, image reconstruction software, software application, software resource, standalone software A set of software programs that utilizes dual spaces algorithms for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. Libraries, extra files and environment variables are not required for the executables. SHELX is intended to be run on a command prompt but may be called from GUIs such as shelXle, Olex2, Oscail or WinGX, or hkl2map., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, image reconstruction software, image analysis software, crystal structure, crystal xray, neutron diffraction, bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1107/S2053273314026370 THIS RESOURCE IS NO LONGER IN SERVICE biotools:shelx https://bio.tools/shelx SCR_014220 2026-09-12 12:58:13 523
Crystallography and NMR System (CNS)
 
Resource Report
Resource Website
1+ mentions
Crystallography and NMR System (CNS) (RRID:SCR_014223) CNS data processing software, data visualization software, software application, software resource, software toolkit Software designed to provide a multi-level hierachical approach for the most commonly used algorithms in macromolecular structure determination. Features include heavy atom searching, experimental phasing (including MAD and MIR), density modification, crystallographic refinement with maximum likelihood targets, and NMR structure calculation using NOEs, J-coupling, chemical shift, and dipolar coupling data. Modules, libraries, utility programs, tutorials, and a syntax manual are available on the website. structure determination, software suite, macromolecular structure determination, data visualization software, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Yale University; Connecticut; USA
PMID:9757107 Available to academic institutions, Request form must be submitted biotools:cnssolve https://bio.tools/cnssolve SCR_014223 Crystallography and NMR System 2026-09-12 12:58:14 8
OpenWalnut
 
Resource Report
Resource Website
OpenWalnut (RRID:SCR_014157) data processing software, data visualization software, software application, software resource Open source tool for multi-modal medical and brain data visualization. It is a tool for the scientific user and a powerful framework for the visualization researcher. It is written in Standard C++ and uses a number of portable libraries (e.g. Qt, Boost and OpenSceneGraph). It runs on common GNU/Linux operating systems, Mac OSX and Windows. open source, data visualization software, brain data, medical tool is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
Free, Available for download, Freely available http://www.openwalnut.org, https://sources.debian.org/src/openwalnut-qt4/ SCR_014157 2026-09-12 12:58:13 0
PsyGeNET
 
Resource Report
Resource Website
10+ mentions
PsyGeNET (RRID:SCR_014406) data analysis software, data or information resource, data processing software, database, software application, software resource Knowledge platform on psychiatric disorders and their genes. Resource for exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of database and set of analysis tools and is the result of the integration of information from DisGeNET and data extracted from the literature by text mining, followed by curation by domain experts. psychiatric disease, associated gene, database, analysis tool, bio.tools is used by: DisGeNET
is listed by: Debian
is listed by: bio.tools
Psychiatric disorder DOI:10.1093/bioinformatics/btv301 Available for the research community biotools:psygenet2r https://bio.tools/psygenet2r SCR_014406 Psychiatric disorders Gene association NETwork, Psychiatric disorders Gene association Network 2026-09-12 12:58:16 11
SCRATCH
 
Resource Report
Resource Website
100+ mentions
SCRATCH (RRID:SCR_014291) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web protein structure and structural feature prediction server.Software suite includes predictors for secondary structure, relative solvent accessibility, disordered regions, domains, disulfide bridges, single mutation stability, residue contacts versus average, individual residue contacts and tertiary structure. User provides amino acid sequence and selects desired predictions, then submits to the server. Protein predictor, secondary structure, relative solvent accessibility, disordered regions, domains, disulfide bridges, single mutation stability, residue contacts versus average, individual residue contacts, tertiary structure prediction, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:15980571 Free, Freely available biotools:scratch https://bio.tools/scratch http://www.igb.uci.edu/servers/psss.html SCR_014291 Scratch Protein Predictor 2026-09-12 12:58:15 141
NNcon
 
Resource Report
Resource Website
1+ mentions
NNcon (RRID:SCR_014292) prediction, software tool Protein contact map prediction is useful for protein folding rate prediction, model selection and 3D structure prediction. Here we describe NNcon, a fast and reliable contact map prediction server and software. NNcon was ranked among the most accurate residue contact predictors in the Eighth Critical Assessment of Techniques for Protein Structure Prediction (CASP8), 2008. text mining objective, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:19420062 biotools:nncon https://bio.tools/nncon http://casp.rnet.missouri.edu/nncon.html SCR_014292 2026-09-12 12:58:15 2
RepeatScout
 
Resource Report
Resource Website
500+ mentions
RepeatScout (RRID:SCR_014653) algorithm resource, data analysis software, data processing software, sequence analysis software, software application, software resource Algorithm used to identify de novo repeat families in newly sequenced genomes. Repeat libraries for C. briggsae, M. muscles (X chromosome), R. novegicus (X chromosome), armadillo, H. sapiens (X chromosome), and various other mammals created using RepeatScout are available on the main site., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. algorithm, sequence analysis, repeat, genome sequence, de novo, repeat family, repeat library, bio.tools is used by: RepeatModeler
is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at San Diego; California; USA
PMID:15961478 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:RepeatScout, biotools:RepeatScout https://bio.tools/RepeatScout, https://bio.tools/RepeatScout, https://bio.tools/RepeatScout SCR_014653 2026-09-12 12:58:20 818

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