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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/devel/bioc/html/CNTools.html
Software package that provides tools to convert the output of segmentation analysis using DNAcopy to a matrix structure with overlapping segments as rows and samples as columns so that other computational analyses can be applied to segmented data.
Proper citation: CNTools (RRID:SCR_000281) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMap.html
Software package that quantifies the similarity of cell populations across multiple flow cytometry samples using a nonparametric multivariate statistical test. The algorithm allows the users to specify a reference sample for comparison or to construct a reference sample from the available data. The output of the algorithm is a set of text files where the cell population labels are replaced by a metaset of population labels, generated from the matching process.
Proper citation: flowMap (RRID:SCR_002269) Copy
https://scicrunch.org/resolver/SCR_002250
THIS RESOURCE IS NO LONGER IN SERVICE. Documented Jul 19, 2024. Metadatabase manually curated that provides web accessible tools related to genomics, transcriptomics, proteomics and metabolomics. Used as informative directory for multi-omic data analysis.
Proper citation: OMICtools (RRID:SCR_002250) Copy
https://www.bioconductor.org/packages//2.13/bioc/html/shinyTANDEM.html
Software package that provides a GUI interface for rTANDEM, an R/Bioconductor package for MS/MS protein identification. The GUI is primarily designed to visualize rTANDEM result object or result xml files. But it will also provides an interface for creating parameter objects, launching searches or performing conversions between R objects and xml files.
Proper citation: shinyTANDEM (RRID:SCR_002169) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMatch.html
Software for matching cell populations and building meta-clusters and templates from a collection of flow cytometry (FC) samples.
Proper citation: flowMatch (RRID:SCR_002283) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMeans.html
Software that identifies cell populations in Flow Cytometry data using non-parametric clustering and segmented-regression-based change point detection.
Proper citation: flowMeans (RRID:SCR_002275) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowMerge.html
Software for merging of mixture components for model-based automated gating of flow cytometry data using the flowClust framework.
Proper citation: flowMerge (RRID:SCR_002224) Copy
https://bioconductor.org/packages/2.11/bioc/html/flowPhyto.html
An R package that performs aggregate statistics on virtually unlimited collections of raw flow cytometry files and provides a memory efficient, parallelized solution for analyzing high-throughput flow cytometric data.
Proper citation: flowPhyto (RRID:SCR_002183) Copy
http://www.bioconductor.org/packages/devel/bioc/html/BEAT.html
Software that implements all bioinformatics steps required for the quantitative, high-resolution analysis of DNA methylation patterns from bisulfite sequencing data.
Proper citation: BEAT (RRID:SCR_002387) Copy
http://www.bioconductor.org/packages/release/bioc/html/CAMERA.html
A Bioconductor package integrating algorithms to extract compound spectra, annotate isotope and adduct peaks, and propose the accurate compound mass even in highly complex data.
Proper citation: CAMERA - Collection of annotation related methods for mass spectrometry data (RRID:SCR_002466) Copy
http://www.bioconductor.org/packages/devel/bioc/html/MethylAid.html
Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored.
Proper citation: MethylAid (RRID:SCR_002659) Copy
http://www.bioconductor.org/packages/devel/bioc/html/CGHnormaliter.html
Software for normalization and centralization of array comparative genomic hybridization (aCGH) data with imbalanced aberrations. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).
Proper citation: CGHnormaliter (RRID:SCR_002936) Copy
http://www.bioconductor.org/packages/release/bioc/html/chimera.html
A Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools. The current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion, tophat-fusion-post and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools.
Proper citation: Chimera (RRID:SCR_002959) Copy
http://www.bioconductor.org/packages/release/bioc/html/triplex.html
Software package that provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many canonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.
Proper citation: Triplex (RRID:SCR_003061) Copy
http://bioinfo.cipf.es/noiseq/doku.php?id=start
Software used for the identification of differentially expressed genes from count data or previously normalized count data. It empirically models the noise distribution of count changes by contrasting fold-change differences (M) and absolute expression differences (D) for all the features in samples within the same condition. This reference distribution is then used to assess whether the M-D values computed between two conditions for a given gene is likely to be part of the noise or represent a true differential expression.
Proper citation: NOISeq (RRID:SCR_003002) Copy
https://bioconductor.org/packages//2.13/bioc/html/virtualArray.html
Software package that permits the user to combine raw data of different microarray platforms into one virtual array. It consists of several functions that act subsequently in a semi-automatic way. Doing as much of the data combination and letting the user concentrate on analyzing the resulting virtual array.
Proper citation: virtualArray (RRID:SCR_001361) Copy
http://www.bioconductor.org/packages/release/bioc/html/stepNorm.html
Software for stepwise normalization functions for cDNA microarray data.
Proper citation: stepNorm (RRID:SCR_001359) Copy
http://www.bioconductor.org/packages/release/bioc/html/rama.html
Software package for robust estimation of cDNA microarray intensities with replicates. It uses a Bayesian hierarchical model for the robust estimation. Outliers are modeled explicitly using a t-distribution, and the model also addresses classical issues such as design effects, normalization, transformation, and nonconstant variance.
Proper citation: RAMA (RRID:SCR_001358) Copy
http://www.bioconductor.org/packages/release/bioc/html/MANOR.html
Software packqge for importation, normalization, visualization, and quality control functions to correct identified sources of variability in array-CGH (Comparative genomic hybridization) experiments.
Proper citation: MANOR (RRID:SCR_001305) Copy
http://www.bioconductor.org/packages/release/bioc/html/dyebias.html
Software package using the GASSCO method for correcting for slide-dependent gene-specific dye bias.
Proper citation: dyebias (RRID:SCR_001308) Copy
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