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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.lajollaneuroscience.org/
Our NINDS Center Core Grant supports centralized resources and facilities shared by investigators with existing NINDS-funded research projects. Our Center is composed of three research cores, each of which will enrich the effectiveness of ongoing research, and promote new research directions. The three Core facilities support Electrophysiology, Neuropathology / Histology, and High-Throughput/High-Content Chemical and Genomic Library screening. By making these important Core Services available to the local Neuroscience community, the La Jolla Neurosciences Program hopes to promote the study of how the nervous system works and develop treatments for nervous system diseases. The cores and their services are available to La Jolla neuroscientists. Core services are available to NINDS-supported neuroscience projects from local investigators as well as young neuroscientists prior to obtaining their first NIH-funded grant. * Electrophysiology: SBMRI Electrophysiology ** The Electrophysiology Core consists of the Sanford-Burnham Electrophysiology Facility. This facility can perform patch-clamp intracellular and extracellular field recordings on a range of material including cultured cells and brain slices. The Sanford-Burnham facility emphasizes electrophysiological analysis of cultured cells and the detailed electrical properties of channels, receptors and recombinant proteins expressed in Xenopus oocytes or mammalian cells. * Neuropathology: UCSD Neuropathology ** The Neuropathology laboratory applies immunocytochemistry, neurochemistry, molecular genetics, transgenic models of disease, and imaging by scanning laser confocal microscopy to analysis of neurological disease in animal models. * Chemical Library Screening: SBIMR Assay Development, SBIMR Chemical Library Screening, SBIMR Cheminformatics, SBIMR High-content Screening ** The Chemical Library Screening core offers high-throughput screening (HTS) of biochemical and cell-based array using traditional HTS readouts and automated microscopy for high-content screening (HCS)> These facilities also offer array development and screening, as well as cheminformatics and medicinal chemistry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026.
Proper citation: La Jolla Interdisciplinary Neurosciences Center (RRID:SCR_002772) Copy
The long range goal of this laboratory is to understand the computational resources of brains from the biophysical to the systems levels. The central issues being addressed are how dendrites integrate synaptic signals in neurons, how networks of neurons generate dynamical patterns of activity, how sensory information is represented in the cerebral cortex, how memory representations are formed and consolidated during sleep, and how visuo-motor transformations are adaptively organized. Additionally, new techniques have been developed for modeling cell signaling using Monte Carlo methods (MCell) and the blind separation of brain imaging data into functionally independent components (ICA).
Proper citation: Computational Neurobiology Laboratory at the Salk Institute (RRID:SCR_002809) Copy
Material resource that provides germ-free and selectively colonized rodents to requesting investigators. Germ-free rodents are axenic, with no detectible bacteria, yeast, molds, parasites or viruses (except retroviruses).
Proper citation: National Gnotobiotic Rodent Resource Center (RRID:SCR_002768) Copy
http://jonathancrabtree.github.io/Circleator/
A Perl-based visualization software tool that generates circular figures of genome-associated data. Common uses of the tool include: * Displaying the sequence and/or genes in a GenBank flat file. * Highlighting differences and/or similarities in gene content between related organisms. * Comparing SNPs and indels between closely-related strains or serovars. * Comparing gene expression values across multiple samples or timepoints. * Visualizing coverage plots of RNA-Seq read alignments.
Proper citation: Circleator (RRID:SCR_002801) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone.. Documented on June 8, 2020.Macaque genomic and proteomic resources and how they are providing important new dimensions to research using macaque models of infectious disease. The research encompasses a number of viruses that pose global threats to human health, including influenza, HIV, and SARS-associated coronavirus. By combining macaque infection models with gene expression and protein abundance profiling, they are uncovering exciting new insights into the multitude of molecular and cellular events that occur in response to virus infection. A better understanding of these events may provide the basis for innovative antiviral therapies and improvements to vaccine development strategies.
Proper citation: Macaque.org (RRID:SCR_002767) Copy
http://www.imexconsortium.org/
Interaction database from international collaboration between major public interaction data providers who share curation effort and develop set of curation rules when capturing data from both directly deposited interaction data or from publications in peer reviewed journals. Performs complete curation of all protein-protein interactions experimentally demonstrated within publication and makes them available in single search interface on common website. Provides data in standards compliant download formats. IMEx partners produce their own separate resources, which range from all encompassing molecular interaction databases, such as are maintained by IntAct, MINT and DIP, organism-centric resources such as BioGrid or MPIDB or biological domain centric, such as MatrixDB. They have committed to making records available, via PSICQUIC webservice, which have been curated to IMEx rules and are available to users as single, non-redundant set of curated publications which can be searched at the IMEx website. Data is made available in standards-compliant tab-deliminated and XML formats, enabling to visualize data using wide range of tools. Consortium is open to participation of additional partners and encourages deposition of data, prior to publication, and will supply unique accession numbers which may be referenced within final article. Submitters may send their data directly to any of member databases using variety of formats, but should conform to guidelines as to minimum information required to describe data.
Proper citation: IMEx - The International Molecular Exchange Consortium (RRID:SCR_002805) Copy
https://www.uab.edu/medicine/neurobiology/
The Department of Neurobiology offers students interested in the nervous system a program of study that leads to the Ph.D. in Neurobiology or a combined M.D./Ph.D. through The University of Alabama School of Medicine located at UAB. The graduate program has numerous faculty members with active research programs from a broad range of areas in contemporary neuroscience with a major focus on topics of biomedical importance. Molecular, cellular and biophysical approaches are emphasized to address fundamental problems of brain function, development and disease. All students take a series of graduate courses in biochemistry and molecular biology, cell biology, ion channel biophysics, synaptic function, developmental neurobiology and medical neurobiology. Evidence of the faculty's national and international impact in fundamental Neuroscience research includes: their substantial number of publications in high impact journals; appointments to editorial boards and editorships of leading neuroscience journals; appointments to NIH and NSF study sections and review boards; awards of over 28 million dollars in annual research grant funds; and numerous invitations to speak at national and international research symposia. Faculty members also have received numerous national and international awards recognizing excellence in research and training.
Proper citation: University of Alabama Neurobiology (RRID:SCR_007493) Copy
https://medicine.tulane.edu/departments/basic-sciences/pharmacology
Department to educate and train medical and graduate students in principles of pharmacology using modern techniques and to conduct state of art research in pharmacology related fields in order to expand frontiers of science and medicine.
Proper citation: Tulane University Medical Center Department of Pharmacology (RRID:SCR_007492) Copy
http://www.uri.edu/pharmacy/programs/graduate/index.shtml
The University of Rhode Island College of Pharmacy is a professional school, but it is also an integral part of University of Rhode Island. The College of Pharmacy fosters a learning-centered, research-oriented educational environment that encourages individuals to make positive life-long contributions to global health. We prepare professional degree students to provide compassionate pharmacist-delivered patient care, and inspire our students through innovative problem-based learning, rich experiential curricula and inter-professional collaboration. We foster a community of scholars who will further the body of knowledge in pharmaceutical, biomedical, and clinical sciences. We strive to improve quality of life: locally, nationally and globally.
Proper citation: University of Rhode Island College of Pharmacy Graduate Programs (RRID:SCR_007529) Copy
The Institute of Neurobiology is an interdisciplinary, interdepartmental research center of the Medical Sciences Campus of the University of Puerto Rico. Its members carry out basic research in Neuroscience, with particular emphasis on the use of simple systems to understand basic mechanisms of nervous system function and development. There are currently 14 full-time faculty members who carry out research and graduate teaching at the Institute. Their research interests range from the development of insect synapses to the anatomy of retinal projections in mammals. Graduate students carrying out research at the Institute are enrolled in Ph.D. and M.Sc. programs in the Medical Sciences Campus and in the Department of Biology, UPR. The Institute houses laboratories equipped for electrophysiology, biochemistry, molecular biology and histology, including confocal and electron microscopy.Located in Old San Juan, the Institute overlooks the Atlantic Ocean and El Morro, the fortress which guards San Juan bay.
Proper citation: University of Puerto Rico Institute of Neurobiology (RRID:SCR_007528) Copy
https://www.jefferson.edu/academics/colleges-schools-institutes/skmc/departments/neurology.html
The Department of Neurology at Jefferson Medical College has a long tradition of excellence in clinical training and care. They are committed to providing an active and exciting research program, exemplified by the Farber Institute for the Neurosciences, established in the spring of 2002. Consolidation of our academic and research base with the neurology ambulatory care facility at the new Jefferson Hospital for the Neurosciences underscores the continuing evolution of the Neurology department, and of its many functions, including, our fully approved residency program.
Proper citation: Thomas Jefferson University Neurology (RRID:SCR_007488) Copy
https://unmhealth.org/services/sleep-medicine/sleep-studies.html
University of New Mexico Health Sciences Center Program in Sleep Medicine Sleep Disorders Center was established in 1983 and was the first nationally accredited sleep disorders center in the State of New Mexico receiving accreditation in March of 1992 from the American Academy of Sleep Medicine. They provide comprehensive services to individuals having symptoms occurring during sleep or while awake due to unrefreshing sleep. The Program combines a state-of-the-art outpatient sleep laboratory, inpatient sleep laboratory, sleep medicine clinic, and trained medical and technical staff dedicated to the diagnosis and treatment of sleep/wake disorders in adults and children. The University of New Mexico Health Sciences Center Program in Sleep Medicine has the distinction of having a first and many onlys attached to it. The criteria for accreditation is very stringent and to date, there is only one other accredited center in the entire state. The Center is also accredited by the Joint Commission on the Accreditation of Health Care Organizations.
Proper citation: University of New Mexico Sleep Disorders Clinic (RRID:SCR_007520) Copy
Department of Pharmacology, Physiology and Therapeutics at the University of North Dakota School of Medicine and Health Sciences is strongly committed to providing their students and the people of North Dakota excellent programs in education, research and service and they are dedicated to the development of leadership, innovation, and scholarly excellence. The translation of fundamental knowledge in the basic sciences to medically relevant problems is a major goal of the department and they are capable of providing the individualized attention and training necessary for the development of the medical scientist of the future.
Proper citation: University of North Dakota Department of Pharmacology Physiology and Therapeutics (RRID:SCR_007523) Copy
https://www.ttuhsc.edu/medicine/pharmacology/default.aspx
The Department of Pharmacology and Neuroscience at Texas Tech University is committed to providing a strong education experience for all trainees. The department's primary areas of training emphasis are neuroscience/ neuropharmacology and cardiovascular/ autonomic pharmacology.Our objective is to prepare students for careers in research and teaching. We currently have 14 faculty and who conduct research in a broad variety of subjects ranging from environmental toxicology to molecular pharmacology. This allows a broad basis for a strong theoretical as well as 'hands-on' education in pharmacology. The faculty of the program work hard to foster a creative and productive research atmosphere, to provide encouragement and positive challenges, and to equip students with the intellectual tools they will need to be good teachers and investigators.
Proper citation: Texas Tech University Department of Pharmacology and Neuroscience (RRID:SCR_007483) Copy
The Neuroscience Research Center (NRC) is a university-wide center where diverse and multidisciplinary research is conducted to further the understanding of neural and behavioral disorders. Whether conducting cellular research in laboratories or clinical trials in patient care settings, the work of NRC researchers may someday contribute to preventing and treating such devastating disorders as: * Dementias resulting from Alzheimer''s disease and stroke * Mental retardation and other learning disabilities * Mental illnesses, including schizophrenia and manic-depressive illness * Alcoholism and other substance abuse problems * Inability to process knowledge due to factors such as aging and head trauma * Disabilities due to disorders of the developing nervous system More than 280 faculty hold NRC appointments, and are on the faculties of the Medical School, School of Public Health, School of Nursing, Dental Branch, and School of Biomedical Informatics. Departments with significant NRC research activities within the Medical School include Neurobiology and Anatomy; Neurology; Neurosurgery; Ophthalmology and Visual Science; Psychiatry and Behavioral Sciences and Radiology. NRC activities are guided by an executive committee appointed by the President of the Health Science Center. The Neuroscience Research Center (NRC) is affiliated with educational opportunities at the graduate and postdoctoral levels.
Proper citation: UTHealth at Houston Neuroscience Research Center (RRID:SCR_007486) Copy
http://www.medicine.tamhsc.edu/basic-sciences/next/index.html
The Department of Neuroscience and Experimental Therapeutics (NExT) at the Texas A&M Health Science Center College of Medicine has 16 full-time faculty members and is one of four basic science departments within the College of Medicine. Program strengths within the department include brain development, cellular/molecular basis of drug addiction, circadian biology, ocular pharmacology and experimental therapeutics, neurobiology of aging, neurodegenerative diseases such as stroke and Alzheimer''s disease, neuro-oncology and neuroteratology of alcohol, nicotine and other drugs of abuse. The Department of Neuroscience and Experimental Therapeutics participates in an interdisciplinary graduate program in the Medical Sciences that leads primarily to the Ph.D. degree with special emphasis in interdisciplinary training in Neurosciences or Pharmaceutical Sciences. The Ph.D. program in Medical Science usually requires 4-5 years to complete. Graduates from our program are prepared for leadership roles in research and teaching in academic, industrial, or governmental positions. Faculty within the department are affiliated with university-wide interdisciplinary faculties including the TAMU Faculty of Neuroscience rand our clinical science partner, the Texas Brain and Spine Institute. The department is also home to the Women''s Health in Neuroscience Program, consisting of interdisciplinary research faculty and a clinical advisory group aimed at developing a cohesive preclinical approach to the impact of puberty, pregnancy and menopause on brain development, mental health and brain disease.
Proper citation: Texas A and M Health Science Center College of Medicine Department of Neuroscience and Experimental Therapeutics (RRID:SCR_007482) Copy
Research in the Department of Pharmacology focuses on three major areas: 1) cardiovascular science 2) cell signaling 3) cancer biology and therapeutics. Within those areas, research ranges from basic biological problems to those with clinical orientations. The cardiovascular science research strives to understand the normal and abnormal functioning of the heart at the molecular, cellular and organ levels, and is exceptionally strong in cardiac electrophysiology and the mechanisms of cardiac arrhythmia. The cell signaling research concerns regulation of cell function by extracellular factors, the molecular biology of signaling pathways, cell communication, and intracellular proteolysis. The cancer biology and therapeutics research is focused on molecular mechanisms regulating cell death and survival in human malignancies, development and testing of novel cancer therapeutics, novel tumor markers, oncogenic transformation and apoptosis, regulation of tumor suppressors and molecular mechanisms of leukemogensis. The Pharmacology Department has multiple research grants for the next five years. Most of the funding comes from the National Institutes of Health (NIH), with additional funding from the Association for International Cancer Research, the American Society of Hematology, the Department of Defense and the American Heart Association.
Proper citation: SUNY Upstate Medical University, Pharmacology (RRID:SCR_007481) Copy
Spanish higher education institution, located in the city of Salamanca, west of Madrid, in the autonomous community of Castile and León. It was founded in 1134 and given the Royal charter of foundation by King Alfonso IX in 1218.
Proper citation: University of Salamanca; Salamanca; Spain (RRID:SCR_007833) Copy
http://purl.bioontology.org/ontology/SPTO
Ontology for Solanaceae crop phenotypes and traits, developed in collaboration with the research community, especially for breeder traits of agronomic importance.
Proper citation: Solanaceae Phenotype Ontology (RRID:SCR_007832) Copy
http://bmserver.sce.ntu.edu.sg/INVERTER/
Software for a de novo exact match tandem repeat finder which main advantage is without the need to specify either the pattern or a particular pattern size, integrated with a data visualization tool and has a built-in user-friendly Graphical User Interface.
Proper citation: INVERTER (RRID:SCR_007956) Copy
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