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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GENE-counter
 
Resource Report
Resource Website
1+ mentions
GENE-counter (RRID:SCR_013056) GENE-counter software resource A computational pipeline for analyzing RNA-Sequencing (RNA-Seq) data for differential gene expression of eukaryotes, prokaryotes, as well as organisms with no available genome reference sequence. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21998647 OMICS_01404, biotools:gene-counter https://bio.tools/gene-counter SCR_013056 2026-08-29 11:24:36 7
CloudAligner
 
Resource Report
Resource Website
1+ mentions
CloudAligner (RRID:SCR_012962) CloudAligner software resource A map/reduce based application for mapping short reads generated by the next-generation sequencing machines. matlab, mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21645377 GNU General Public License, v3 OMICS_00656, biotools:cloudaligner https://bio.tools/cloudaligner SCR_012962 2026-08-29 11:24:35 4
seqMINER
 
Resource Report
Resource Website
100+ mentions
seqMINER (RRID:SCR_013020) seqMINER software resource Software for a genome wide mapping data interpretation platform for NGS (ChIPSeq). java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21177645 GNU General Public License, v3 biotools:seqminer, OMICS_00460 https://bio.tools/seqminer SCR_013020 2026-08-29 11:24:26 190
cn.mops
 
Resource Report
Resource Website
10+ mentions
cn.mops (RRID:SCR_013036) cn.mops software resource A data processing pipeline for copy number variations and aberrations (CNVs and CNAs) from next generation sequencing (NGS) data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
biotools:cn.mops, OMICS_00335 https://bio.tools/cn.mops SCR_013036 Copy Number estimation by a Mixture Of PoissonS 2026-08-29 11:24:36 10
TopHat
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
TopHat (RRID:SCR_013035) alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Software tool for fast and high throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies. Fast splice junction mapper for RNA-Seq reads. Aligns RNA-Seq reads to mammalian-sized genomes using ultra high-throughput short read aligner Bowtie, and then analyzes mapping results to identify splice junctions between exons.TopHat2 is accurate alignment of transcriptomes in presence of insertions, deletions and gene fusions. align, RNA-Seq, read, cDNA, sequencing, transcriptomics, fast, splice, junction, mapper, exon, analysis, bio.tools uses: Bowtie
is used by: CIRCexplorer
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: HISAT2
has parent organization: University of Maryland; Maryland; USA
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: University of Washington; Seattle; USA
works with: GeneScissors
NHGRI R01 HG006102;
NHGRI R01 HG006677
PMID:23618408
PMID:19289445
DOI:10.1093/bioinformatics/btp120
Free, Available for download, Freely available biotools:tophat, OMICS_01257 https://github.com/infphilo/tophat, https://bio.tools/tophat, https://sources.debian.org/src/tophat/ http://tophat.cbcb.umd.edu/ SCR_013035 tophat, TopHat1, Tophat2 2026-08-29 11:24:28 9789
SAMMate
 
Resource Report
Resource Website
10+ mentions
SAMMate (RRID:SCR_013037) SAMMate software resource An open source GUI software suite to process RNA-Seq data. It is composed of two modules: assemblySAM and SAMMate. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
biotools:sammate, OMICS_01264 https://bio.tools/sammate SCR_013037 2026-08-29 11:24:26 11
Flexbar
 
Resource Report
Resource Website
100+ mentions
Flexbar (RRID:SCR_013001) Flexbar software resource Flexible barcode and adapter removal for sequencing platforms. bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
DOI:10.3390/biology1030895 biotools:flexbar https://bio.tools/flexbar, https://sources.debian.org/src/flexbar/ SCR_013001 2026-08-29 11:24:27 307
LOCAS
 
Resource Report
Resource Website
1+ mentions
LOCAS (RRID:SCR_013064) LOCAS software resource A software to assemble short reads of next generation sequencing technologies at low coverage. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21858125 OMICS_00019, biotools:locas https://bio.tools/locas SCR_013064 2026-08-29 11:24:29 2
PRICE
 
Resource Report
Resource Website
100+ mentions
PRICE (RRID:SCR_013063) PRICE software resource Software for a de novo genome assembler implemented in C++. c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at San Francisco; California; USA
OMICS_01430, biotools:price https://bio.tools/price SCR_013063 Paired-Read Iterative Contig Extension 2026-08-29 11:24:27 165
OntoQuest
 
Resource Report
Resource Website
OntoQuest (RRID:SCR_013281) OntoQuest software resource An ontology management module to perform ontology-based search over data sources. This management system permits a user to store, search and navigate any number of OWL-structured ontologies. Ontoquest may also be accessed through a variety of web services via the Neuroscience Information Framework. ontology, interoperability, owl, middleware, web service, bio.tools, bio.tools is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
is related to: NIFSTD
is related to: NIF Web Services
has parent organization: Neuroscience Information Framework
PMID:18958629 biotools:list_ontologies, biotools:ontoquest_ws, nlx_151737 https://bio.tools/list_ontologies, https://bio.tools/ontoquest_ws SCR_013281 Ontoquest 2026-08-29 11:24:33 0
RDXplorer
 
Resource Report
Resource Website
1+ mentions
RDXplorer (RRID:SCR_013290) RDXplorer software resource A computational tool for copy number variants (CNV) detection in whole human genome sequence data using read depth (RD) coverage. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
biotools:RDXplorer, OMICS_00349 https://bio.tools/RDXplorer SCR_013290 2026-08-29 11:24:30 7
GeneSigDB
 
Resource Report
Resource Website
10+ mentions
GeneSigDB (RRID:SCR_013275) GeneSigDB analysis service resource, data access protocol, data analysis service, data or information resource, data repository, database, production service resource, service resource, software resource, storage service resource, web service Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service. gene, gene signature, curated gene signature, gene expression, gene expression signature, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Computational Biology and Functional Genomics Laboratory at Harvard
Cancer Genome Research Institute ;
Dana-Farber Cancer Institute ;
Women's Cancers Program ;
Claudia Adams Barr Foundation ;
NLM 1R01 LM010129;
NCI 1U19 CA148065;
NHGRI 1P50 HG004233
PMID:22110038 biotools:genesigdb, nlx_149342 https://bio.tools/genesigdb SCR_013275 Gene Signature Data Base, GeneSigDB - Curated Gene Signatures Database 2026-08-29 11:24:33 24
PlantNATsDB - Plant Natural Antisense Transcripts DataBase
 
Resource Report
Resource Website
1+ mentions
PlantNATsDB - Plant Natural Antisense Transcripts DataBase (RRID:SCR_013278) PlantNATsDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Natural Antisense Transcripts (NATs), a kind of regulatory RNAs, occur prevalently in plant genomes and play significant roles in physiological and/or pathological processes. PlantNATsDB (Plant Natural Antisense Transcripts DataBase) is a platform for annotating and discovering NATs by integrating various data sources involving approximately 2 million NAT pairs in 69 plant species. PlantNATsDB also provides an integrative, interactive and information-rich web graphical interface to display multidimensional data, and facilitate plant research community and the discovery of functional NATs. GO annotation and high-throughput small RNA sequencing data currently available were integrated to investigate the biological function of NATs. A ''''Gene Set Analysis'''' module based on GO annotation was designed to dig out the statistical significantly overrepresented GO categories from the specific NAT network. PlantNATsDB is currently the most comprehensive resource of NATs in the plant kingdom, which can serve as a reference database to investigate the regulatory function of NATs. natural antisense transcript, annotation, high-throughput, small rna sequencing, function, regulatory function, predict, sequence, small rna, blast, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Gene Expression Omnibus
has parent organization: Zhejiang University; Zhejiang; China
National Natural Sciences Foundation of China 30971743;
National Natural Sciences Foundation of China 31050110121;
National Natural Sciences Foundation of China 31071659;
Ministry of Science and Technology of China 2009DFA32030;
Program for New Century Excellent Talents in University of China NCET-07-0740;
Huazhong Agricultural University Scientific and Technological Self-innovation Foundation 2010SC07
PMID:22058132 Free nlx_151492, biotools:plantnatsdb https://bio.tools/plantnatsdb SCR_013278 Plant Natural Antisense Transcripts DataBase 2026-08-29 11:24:30 9
CEM
 
Resource Report
Resource Website
1+ mentions
CEM (RRID:SCR_013241) CEM software resource An algorithm to assemble transcripts and estimate their expression levels from RNA-Seq reads. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at Riverside; California; USA
OMICS_01271, biotools:cem https://bio.tools/cem SCR_013241 CEM: Transcriptome Assembly and Isoform Expression Level Estimation from Biased RNA-Seq Reads 2026-08-29 11:24:32 1
BEADS
 
Resource Report
Resource Website
10+ mentions
BEADS (RRID:SCR_013229) BEADS software resource Software for a normalization scheme that corrects nucleotide composition bias, mappability variations and differential local DNA structural effects in deep sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: University of Cambridge; Cambridge; United Kingdom
PMID:21646344 OMICS_00466, biotools:beads https://bio.tools/beads SCR_013229 BEADS: Bias Elimination Algorithm for Deep Sequencing, Bias Elimination Algorithm for Deep Sequencing 2026-08-29 11:24:29 38
SeWeR - SEquence analysis using WEb Resources
 
Resource Report
Resource Website
SeWeR - SEquence analysis using WEb Resources (RRID:SCR_004167) data or information resource, portal, service resource, software resource, topical portal Sequence analysis using Web Resources (SeWeR) is an integrated, Dynamic HTML (DHTML) interface to commonly used bioinformatics services available on the World Wide Web. It is highly customizable, extendable, platform neutral, completely server-independent and can be hosted as a web page as well as being used as stand-alone software running within a web browser. It doesn''t require any server to host itself. The goal of SeWeR is to turn your web-browser into a powerful sequence-analysis tool. It is written entirely in JavaScript1.2. SeWeR can be downloaded and mirrored freely. The whole package is just around 300K. You can even run it from a floppy. SeWeR is not compatible with Netscape 6. SeWeR now generates graphics. Savvy is a plasmid drawing software that generates plasmid map in the revolutionary Scalable Vector Graphics format from W3C. nucleic acid, protein, pcr, alignment, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Centre for Cellular and Molecular Biology; Hyderabad; India
PMID:11395442 biotools:sewer, nlx_18981 https://bio.tools/sewer SCR_004167 SEquence analysis using WEb Resources, SeWeR 2026-08-29 11:22:05 0
PerM
 
Resource Report
Resource Website
50+ mentions
PerM (RRID:SCR_004223) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package to perform highly efficient genome scale alignments for hundreds of millions of short reads produced by the ABI SOLiD and Illumina sequencing platforms. It capable of providing full sensitivity for alignments within 4 mismatches for 50bp SOLID reads and 9 mismatches for 100bp Illumina reads.Efficient mapping of short sequencing reads with periodic full sensitive spaced seeds. Short sequencing mapping, short sequencing read, next-generation sequencing, genome, alignment, short read, abi, solid, illumina, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Clippers
has parent organization: Google Code
has parent organization: University of Southern California; Los Angeles; USA
PMID:19675096
DOI:10.1093/bioinformatics/btp486
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00675, biotools:perm https://bio.tools/perm, https://sources.debian.org/src/perm/ SCR_004223 PERiodic seed Mapping, Periodic seed Mapping 2026-08-29 11:21:49 60
TAGS
 
Resource Report
Resource Website
100+ mentions
TAGS (RRID:SCR_004294) TAGS data analysis software, data processing software, software application, software resource, time-series analysis software Software tool for gene set enrichment analysis for expression time series, which can incorporate existing knowledge and analyze the dynamic property of a group of genes that have functional or structural associations. The installation file is for Windows., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, enrichment analysis, time series, function, structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Tsinghua University; Beijing; China
THIS RESOURCE IS NO LONGER IN SERVICE biotools:tags, nlx_31187 https://bio.tools/tags http://166.111.130.26/member/yliu/TAGS/ SCR_004294 2026-08-29 11:22:00 139
BSRD
 
Resource Report
Resource Website
10+ mentions
BSRD (RRID:SCR_004249) BSRD data or information resource, data repository, database, service resource, storage service resource A repository for bacterial small regulatory RNA. They welcome you to submit new experimental validated sRNA targets. srna target, srna, small regulatory non-coding rna, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23203879 Acknowledgement requested, The community can contribute to this resource biotools:bsrd, OMICS_01533 https://bio.tools/bsrd SCR_004249 BSRD - Bacterial Small Regulatory RNA Database, Bacterial Small Regulatory RNA Database 2026-08-29 11:22:06 29
STAR
 
Resource Report
Resource Website
10000+ mentions
STAR (RRID:SCR_004463) alignment software, data processing software, image analysis software, software application, software resource Software performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays. RNA-seq data, alignment, RNA-seq reads alignment, reference genome, using uncompressed suffix arrays, bio.tools is used by: STARsolo
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
NHGRI U54 HG004557 PMID:23104886
DOI:10.1093/bioinformatics/bts635
biotools:star, OMICS_01254, SCR_015899 https://github.com/alexdobin/STAR, https://bio.tools/star, https://sources.debian.org/src/rna-star/ SCR_004463 Spliced Transcripts Alignment to Reference, Spliced Transcripts Alignment to a Reference (STAR), rna-star, ultrafast universal RNA-seq aligner 2026-08-29 11:22:05 26381

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