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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/flowUtils.html
Software that provides utilities for flow cytometry data.
Proper citation: flowUtils (RRID:SCR_001879) Copy
http://cran.r-project.org/web/packages/kdetrees/
R package using a non-parametric method for estimating distributions of phylogenetic trees, with the goal of identifying trees that are significantly different from the rest of the trees in the sample.
Proper citation: Kdetrees (RRID:SCR_004522) Copy
http://ftp://lausanne.isb-sib.ch/pub/databases/Bgee/general/IQRray.R
Software based on evolutionary conservation of expression profiles, implemented in R, for identification of poor quality arrays in dataset composed of arrays from many independent experiments.
Proper citation: IQRray (RRID:SCR_006057) Copy
http://cran.r-project.org/web/packages/YuGene/
Software providing a simple method for comparison of gene expression generated across different experiments, and on different platforms; that does not require global renormalization, and is not restricted to comparison of identical probes. YuGene works on a range of microarray dataset distributions, such as between manufacturers. The resulting output allows direct comparisons of gene expression between experiments and experimental platforms.
Proper citation: YuGene (RRID:SCR_006023) Copy
https://bitbucket.org/cob87icW6z/cafe/wiki/Home
R software package for the detection of gross chromosomal abnormalities from gene expression microarray data.
Proper citation: CAFE (RRID:SCR_005983) Copy
http://www.bioconductor.org/packages/devel/bioc/html/RUVSeq.html
Software package that implements the remove unwanted variation (RUV) methods for the normalization of RNA-Seq read counts between samples.
Proper citation: RUVSeq (RRID:SCR_006263) Copy
Statistical software to estimate tumor purity, ploidy and absolute copy numbers from next generation sequencing data.
Proper citation: AbsCN-seq (RRID:SCR_006409) Copy
http://cran.r-project.org/web/packages/aLFQ/
An R-package for estimating absolute protein quantities from label-free liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics data. It supports the commonly used absolute label-free protein abundance estimation methods (TopN, iBAQ, APEX, NSAF and SCAMPI) for LC-MS/MS proteomics data, quantifying on either MS1-, MS2-levels or spectral counts together with validation algorithms to enable automated data analysis and error estimation. Specifically, they used Monte-carlo cross-validation and bootstrapping for model selection and imputation of proteome-wide absolute protein quantity estimation.
Proper citation: aLFQ (RRID:SCR_005925) Copy
http://www-math.u-strasbg.fr/genpred/spip.php?article3
R software package to study, predict and simulate the diffusion of a signal through a temporal gene network. It predicts changes in gene expressions after a biological perturbation in the network and provides graphical outputs that allow monitoring the spread of a signal through the network., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Cascade (RRID:SCR_005861) Copy
http://biit.cs.ut.ee/gprofiler/
Web server for functional enrichment analysis and conversions of gene lists. Web based tool for functional profiling of gene lists from large scale experiments. Has web interface with powerful visualization. Used for analyzing data from any organism.
Proper citation: g:Profiler (RRID:SCR_006809) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/bars.htm
Software application that is a statistical method that bridges the gap between single-locus and haplotype-based tests of association. It is based on the non-parametric regression techniques embodied by Bayesian Adaptive Regression Splines. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: BARS (RRID:SCR_009123) Copy
https://github.com/dbitton/LaSSO
An R script that creates a FASTA database containing all possible lariat signatures from a given set of introns.
Proper citation: LaSSO (RRID:SCR_003418) Copy
http://cran.r-project.org/web/packages/FisHiCal/
Software that integrates Hi-C and FISH data, offering a modular and easy-to-use tool for chromosomal spatial analysis.
Proper citation: FisHiCal (RRID:SCR_002799) Copy
https://github.com/ahmohamed/NetPathMiner
Software that implements a flexible module-based process flow for network path mining and visualization, which can be fully inte-grated with user-customized functions. It supports construction of various types of genome scale networks from three different pathway file formats (KGML, SBML and BioPAX), enabling its utility to most common pathway databases. In addition, it provides different visualization techniques to facilitate the analysis of even thousands of output paths.
Proper citation: NetPathMiner (RRID:SCR_002757) Copy
http://www.bioconductor.org/packages/devel/bioc/html/CGHnormaliter.html
Software for normalization and centralization of array comparative genomic hybridization (aCGH) data with imbalanced aberrations. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).
Proper citation: CGHnormaliter (RRID:SCR_002936) Copy
http://www.bioconductor.org/packages/release/bioc/html/chimera.html
A Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools. The current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion, tophat-fusion-post and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools.
Proper citation: Chimera (RRID:SCR_002959) Copy
http://cran.r-project.org/web/packages/pairheatmap/
A software tool to compare two heatmaps and discover patterns within and across groups. In the context of biology, group can be defined based on gene ontology.
Proper citation: pairheatmap (RRID:SCR_003109) Copy
http://www.bioconductor.org/packages/release/bioc/html/triplex.html
Software package that provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many canonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.
Proper citation: Triplex (RRID:SCR_003061) Copy
http://cran.r-project.org/web/packages/enviPat/
Software for fast and very memory-efficient calculation of isotope patterns, subsequent convolution to theoretical envelopes (profiles) plus valley detection and centroidization or intensoid calculation. Batch processing, resolution interpolation, wrapper, adduct calculations and molecular formula parsing.
Proper citation: enviPat (RRID:SCR_003034) Copy
http://r3cseq.genereg.net/Site/index.html
An R/Bioconductor package to identify chromosomal interaction regions generated by chromosome conformation capture (3C) coupled to next-generation sequencing (NGS), a technique termed 3C-seq. It performs data analysis for a number of different experimental designs, as it can analyze 3C-seq data with or without a control experiment and it can be used to facilitate data analysis for experiments with multiple replicates. The r3Cseq package provides functions to perform data normalization, statistical analysis for cis/trans interactions and visualization in order to help scientists identify genomic regions that physically interact with the given viewpoints of interest. This tool greatly facilitates hypothesis generation and the interpretation of experimental results.
Proper citation: r3Cseq (RRID:SCR_003198) Copy
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