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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
The Beckman Institute BNMC brings together researchers from many disciplines at Caltech to address problems in the mechanistic modeling of coupled genomic, intercellular and intracellular processes. It represents an attempt to encourage closer interaction and collaboration between groups in Biology, Control and Dynamical Systems, and the Center for Advanced Computing Research. The focus of BNMC is biochemical phenomena occurring within and between cells, in particular the mechanistic modeling of molecular networks of all kinds (e.g., transcriptional, regulatory, metabolic, signal transduction, mechanical, etc.) with and without spatial variation and intercellular communication. BNMC is formed as a coordinated effort aimed at (1) applying existing capabilities to collaboratively solve biological modeling problems that arise in answering scientific questions in Caltech laboratories, (2) exploring a diversity of novel approaches in order to achieve fundamental advances necessary to address the classes of modeling problems biologists want to solve, and (3) organizing projects to better share human experience as well as common infrastructure to avoid duplication and maximize solution interoperability.
Proper citation: Caltech, The Beckman Institute: The Biological Network Modeling Center (RRID:SCR_008060) Copy
https://bioinformatics.forsyth.org/
Core specializes in oral microbial genomics, taxonomy, phylogenetics and the next generation sequence (NGS) data analysis with both in house and cloud high performance computational resource. In addition to supporting funded bioinformatics projects, Bioinformatics Core will also provide computational support to Forsyth and other researchers for processing, analyzing, and interpreting biological data.
Proper citation: Forsyth Institute Bioinformatics Core Facility (RRID:SCR_009783) Copy
http://www.sanger.ac.uk/science/tools/ssaha2-0
A program designed for the efficient mapping of sequence reads onto genomic references. The software is capable of reading most sequencing platforms and giving a range of outputs are supported.
Proper citation: Sequence Search and Alignment by Hashing Algorithm (RRID:SCR_000544) Copy
http://www.scienceexchange.com/facilities/centrillion-biosciences-inc
Centrillion offers a portfolio of genomic services to academic, clinical and industrial researchers. Core provides experimental design consultation, data production services, and bioinformatics analyses for a wide variety of genomic applications. Core offers access to next-gen sequencing, genotyping and bioinformatics analysis.
Proper citation: Centrillion Biosciences Inc. (RRID:SCR_012358) Copy
http://www.salk.edu/science/core-facilities/integrative-genomics-and-bioinformatics-core/
Core facility established to assist the Salk community with integrating genomics data into their research. The primary focus of the core is to provide analysis support for next-generation sequencing applications.
Proper citation: Salk Institute Razavi Newman Integrative Genomics and Bioinformatics Core Facility (IGC) (RRID:SCR_014842) Copy
Core laboratory for nucleic acid sequencing and bioinformatics. Used for research support, education, and training. Services include genomic techniques and applications, sequencing technologies, and bioinformatics analyses, writting letters of support for grant applications submitted to funding agencies. GGBC operates multiple platforms for short-, long-, and single-molecule sequencing reads (i.e., Illumina MiSeq and NextSeq, PacBio Sequel, and Oxford Nanopore MinIon).
Proper citation: Georgia Genomics and Bioinformatics Core at the University of Georgia (RRID:SCR_010994) Copy
http://bioinf.wehi.edu.au/folders/melanie/haploclusters.html
Software program designed to detect excess haplotypes sharing in datasets consisting of case and control haplotypes. Excess haplotype sharing can be seen around disease loci in case samples since LD persists longer here than in the controls where LD is persisting only according to the relatedness of the individuals in the population, i.e. the age of the population. (entry from Genetic Analysis Software)
Proper citation: HAPLOCLUSTERS (RRID:SCR_007439) Copy
http://gaow.github.io/genetic-analysis-software/l-1.html#ldsupport
Software application (entry from Genetic Analysis Software)
Proper citation: LDSUPPORT (RRID:SCR_007036) Copy
http://cedar.genetics.soton.ac.uk/pub/PROGRAMS/BETA
Software application for non-parametric linkage analysis using allele sharing in sib pairs (entry from Genetic Analysis Software)
Proper citation: BETA (RRID:SCR_007556) Copy
http://www.wesbarris.com/mapcreator/
Software application to create gene maps using either radiation hybrid data or linkage data (entry from Genetic Analysis Software)
Proper citation: MAPCREATOR (RRID:SCR_008001) Copy
http://www.sph.umich.edu/csg/abecasis/GOLD/
Software package that provides a graphical summary of linkage disequilibrium in human genetic data. The graphical summary is well suited to the analysis of dense genetic maps, where contingency tables are cumbersome to interpret. An interface to the Simwalk2 application allows for the analysis of family data.
Proper citation: Graphical Overview of Linkage Disequilibrium (RRID:SCR_007151) Copy
http://bios.ugr.es/BMapBuilder/
Software application (entry from Genetic Analysis Software)
Proper citation: BMAPBUILDER (RRID:SCR_007264) Copy
https://cran.r-project.org/web/packages/stepwise/index.html
Software application that is a stepwise approach to identifying recombination breakpoints in a sequence alignment (entry from Genetic Analysis Software)
Proper citation: R/STEPWISE (RRID:SCR_007420) Copy
NIH initiative to support production of cDNA libraries, clones and 5'/3' sequences and to provide set of full-length (open reading frame) sequences and cDNA clones of expressed genes for Xenopus laevis and Xenopus tropicalis. Clones distribution is outsourced to for profit companies. Project concluded in September 2008. Resources generated by XGC are publicly accessible to biomedical research community. All sequences are deposited into GenBank.Corresponding clones are available through IMAGE clone distribution network. With conclusion of XGC project, GenBank records of XGC sequences will be frozen, without further updates. Since knowledge of what constitutes full-length coding region for some of genes and transcripts for which we have XGC clones will likely change in future, users planning to order XGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene).
Proper citation: Xenopus Gene Collection (RRID:SCR_007023) Copy
http://www.mds.qmw.ac.uk/statgen/dcurtis/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application for TDT test on markers with more than two alleles using a logistic regression analysis. (entry from Genetic Analysis Software).
Proper citation: ETDT (RRID:SCR_007576) Copy
Part of zebrafish genome project. ZGC project to produce cDNA libraries, clones and sequences to provide complete set of full-length (open reading frame) sequences and cDNA clones of expressed genes for zebrafish. All ZGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of ZGC project in September 2008, GenBank records of ZGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which we have ZGC clones will likely change in future, users planning to order ZGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene).
Proper citation: Zebrafish Gene Collection (RRID:SCR_007054) Copy
http://www-gene.cimr.cam.ac.uk/clayton/software/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2023. Software application that tests for association between genetic marker and disease by examining the transmission of markers from parents to affected offspring. The main features which differ from other similar programs are: (1) It can deal with transmission of multi-locus haplotypes, even if phase is unknown, and (2) Parental genotypes may be unknown. (entry from Genetic Analysis Software)
Proper citation: TRANSMIT (RRID:SCR_007571) Copy
http://gaow.github.io/genetic-analysis-software/l/linkage---ceph/
Software application (entry from Genetic Analysis Software)
Proper citation: LINKAGE - CEPH (RRID:SCR_007048) Copy
http://compgen.rutgers.edu/multimap.shtml
Software program for automated construction of genetic maps (entry from Genetic Analysis Software)
Proper citation: MULTIMAP (RRID:SCR_007168) Copy
https://github.com/gaow/genetic-analysis-software/blob/master/pages/MAPMAKER%26SIBS.md
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. Data analysis software for complete multipoint analysis.
Proper citation: MAPMAKER/SIBS (RRID:SCR_008012) Copy
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