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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://med.stanford.edu/tktc.html
Services include genome editing of mice, rats and cell lines, mouse line cryopreservation and re-derivation, ES cell targeting, PDX models, drug screening.Crispr Mediated KO/KI and Conditional KO Mice,KI mouse by mouse ES cell genome editing,Integrase Mediated Transgenesis,Conventional Transgenic Mouse,Mouse Line Services,Cell Line Services. Tumor Model Services include In vivo tumor models,In vivo pharmacology,In vitro and biochemical assays,Translational imaging services.
Proper citation: Stanford University School of Medicine Transgenic, Knockout and Tumor model Center Core Facility (RRID:SCR_023382) Copy
https://www.cores.emory.edu/fcc/
Core provides sorting, sample analysis and analyzer training.Provides quantitative flow cytometric analyses on samples including blood, bone marrow, spleen, serum, plasma, solid tissues, cell extracts to support both clinical and basic research efforts. These analyses will provide insight on cell function and precursors whose abundance can be monitored as biomarkers to predict and follow progression of a wide range of diseases, such as H1N1, yellow fever, dengue, neurodegenerative diseases, stem cell studies.Provides consultations, expert training, and support for all systems and provides access to equipment.
Proper citation: Emory University School of Medicine Flow Cytometry Core Facility (RRID:SCR_023536) Copy
https://www.cores.emory.edu/tmf/index.html
Provides equipment and expertise for generating and characterizing genetically altered mouse models. Please contact us so that we can discuss your experimental needs.
Proper citation: Emory University Mouse Transgenic and Gene Targeting Core Facility (RRID:SCR_023535) Copy
Provides services with computing and data information for research proposals, data storage platforms,consultation,computational platforms and resources.Some services relate directly to physical hardware, including hosting and system administration. Hosting largely takes place at Stanford Research Computing Facility data center designed specifically to host high density, power consumptive computing equipment. SRCF is intended to meet research server hosting needs of campus for years to come.
Proper citation: Stanford University Research Computing (RRID:SCR_023413) Copy
https://www.cores.emory.edu/ici/index.html
Provides light microscopy. Offers expertise in imaging for experimental needs.
Proper citation: Emory University Emory Integrated Cellular Imaging Core Facility (RRID:SCR_023534) Copy
https://physics.stanford.edu/resources/machine-shop
Provides services for all departments on campus, including library of materials and parts suppliers, arranging for off-campus services such as plating and specialized machining services,help with laboratory and research apparatus and repair of existing equipment, designs from sketches to final assembly by mechanical means (welding, brazing or soldering),computer numerically controlled mill and lathe, electro discharge machining.
Proper citation: Stanford University Physics Machine Shop Core Facility (RRID:SCR_023412) Copy
https://winshipcancer.emory.edu/research/shared-resources/emory-cellular-immunotherapy-core.html
Clinical cell manufacturing facility that prepares cell and immunotherapy products under current Good Manufacturing Practices for development of investigational new drugs and diagnostics methods.Provides GMP compliant cell manufacturing and/or consultation for translational of Emory based or external research collaborations into early phase clinical trials.
Proper citation: Emory University Emory Cellular and Immunotherapy Core Facility (RRID:SCR_023533) Copy
Offers to run high-throughput compound, RNAi, and deletion library based screens for purpose of network analysis, drug and/or target discovery. Offers assistance to develop assay, carryout screen and/or analyze data. Equipment is also available for general (low-throughput) use. Helps with developing custom pipeline. Biomek FX liquid handling workstation with integrated Liconic shaker incubator (temperature, humidity, and CO2 controlled) can be used to setup and grow most cell types in 96 well plates. This robot is equipped to add RNAi constructs, drugs or other stimuli to each plate. Biomek FX can also be used to perform high-throughput biochemical assays. Cell based assays can be carried out using either Operetta CLS high-content analysis system or CLARIOstar plus. Both instruments have powerful, but easy to use software for data analysis.
Proper citation: University of Arizona Functional Genomics Core Facility (RRID:SCR_023433) Copy
https://med.miami.edu/research/cores/biomarker-and-immunoassay-laboratory
Provides biomarker testing for human clinilcal research studies across multiple disciplines.Provides expertise with chemistry, special chemistry, radioimmunoassay, nephelometric and ELISA and multiplexing assay methods utilizing automated and manual procedures. Laboratory has Clinical Laboratory Improvement Act certification and follows guidelines established by CLIA for quality control and proficiency testing to ensure results. Core coordinates proper pre-analytical sample collection and processing procedures with project leaders; performs biochemical assays on samples submitted to the laboratory by investigators in manner that assures strict quality control both within and between assay runs; reports results to project staff in timely fashion; makes available expertise and technical assistance for establishing and validating new methodologies to support University of Miami investigators.
Proper citation: University of Miami Miller School of Medicine Biomarkers and Immunoassay Laboratory Core Facility (RRID:SCR_023705) Copy
https://rnainnovation.med.upenn.edu/scientific-groups/targeting-core/
Core to support advancement of RNA biotherapeutics via enabling swift and low failure solutions of targeting related aspects. Provides methodologies, equipment, reagents, expertise and support in identification of epitopes and ligands, molecular design and testing of targeting RNA to diverse multitudes of desirable addresses in the body.
Proper citation: University of Pennsylvania Institute for RNA Innovation Targeting Core Facility (RRID:SCR_024573) Copy
https://www.med.upenn.edu/immunehealth/
Core provides infrastructure and technical support for scaling clinical immune profiling of large scale clinical cohorts. Provides biospecimen processing, sample storage, high dimensional immune assays, computational analysis, and project management. Services are only available to investigators and teams whose cohorts have been approved by the Immune Health leadership.
Proper citation: University of Pennsylvania Institute for Immunology and Immune Health I3H Core Facility (RRID:SCR_024574) Copy
https://www.huck.psu.edu/core-facilities/cryo-electron-microscopy-facility
Cryo-Electron Microscopy Facility houses FEI Titan Krios microscope that offers data collection for life sciences while incorporating materials science applications. Used for creating super high definition 3D images of atoms and molecules. Facility allows for fully automated atomic resolution single particle and high contrast tomography tilt-series data collection. Additional microscopy components permit a full range of materials science applications, including EELS, STEM, and DPC. Facility also houses ThermoFisher Arctica G2.
Proper citation: Pennsylvania State University Huck Institutes Cryo-Electron Microscopy Core Facility (RRID:SCR_024456) Copy
https://research.pasteur.fr/en/team/human-disease-models-core-facility/
Core Facility produces mice harboring human immune system and provides expertise for possible applications of this model. HIS mice engrafted with human Hematopoietic stem cells are advantageous in vivo models for long term studies in field of human immune cells biology, immune oncology and infectious disease. They constitute small animal model in which to analyze potency and safety of small animal model modulating immune system.
Proper citation: Pasteur Institute Human Disease Models Core Facility (RRID:SCR_023881) Copy
https://tnprc.tulane.edu/infectious-disease-aerobiology-core
Core focuses on infectious disease aerobiology. Core facilitates biomedical research efforts that require unique demands of aerosol and aerobiology in their respective performance.
Proper citation: Tulane University TNBRC Infectious Disease Aerobiology Core Facility (RRID:SCR_024608) Copy
https://tnprc.tulane.edu/clinical-pathology-core
Clinical Pathology Core performs clinical diagnostic testing for all research and colony animals. This includes complete blood counts, routine chemistry panels, and microbial culture workups. The lab is equipped with Sysmex XN1000v veterinary hematology analyzer, Beckman AU480 chemistry analyzer, and Matrix assisted laser desorption ionization time of flight MALDI-TOF instrument for microbe identification. CPC is staff with American Society of Clinical Pathologist certified licensed Medical Technologists.
Proper citation: Tulane University TNBRC Clinical Pathology Core Facility (RRID:SCR_024609) Copy
Core Facility offers equipment for wide range of light microscopy applications as well as access to advanced bioimaging software. Specialized staff offers personal training and assistance.
Proper citation: Aarhus University Bioimaging Core Facility (RRID:SCR_023876) Copy
https://www.beatson.gla.ac.uk/advanced-technologies/bair.html
Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.
Proper citation: Beatson Institute for Cancer Research United Kingdom Beatson Advanced Imaging Resource Core Facility (RRID:SCR_023875) Copy
https://tnprc.tulane.edu/anatomic-pathology-core
Anatomic Pathology Core is responsible for post-mortem examinations, tissue collection and distribution, fixation, processing, slide preparation, routine and special staining, and diagnostic gross and histologic pathology services. Processes and interprets biopsy specimens for both research and diagnostic purposes and provides tissue trimming, paraffin processing, sectioning, and routine and special staining for clinical and research staff and faculty. APC works closely with clinical veterinarians, and through diagnostic pathology on biopsies and necropsies, plays major role in monitoring and maintaining health of animals in breeding colonies.
Proper citation: Tulane University TNBRC Anatomic Pathology Core Facility (RRID:SCR_024606) Copy
https://www.huck.psu.edu/core-facilities/proteomics-and-mass-spectrometry-core-facility
Facility offers highly sensitive and accurate mass spectrometry analysis, including identification and quantitation of proteins by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) or by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-TOF-MS).
Proper citation: Pennsylvania State University Huck Institutes Proteomics and Mass Spectrometry Core Facility (RRID:SCR_024462) Copy
https://www.research.chop.edu/biorepository-resource-center
Core with capacity for approximately 2 million to 3 million samples, serves CHOP’s biobanking needs, avoiding specimen duplication, preserving precious materials, and providing organized data and materials. The BioRC operates under the following principles: An Operational Committee, which coordinates central and investigator-specific biobanking resources and programs at CHOP, governs and approves requests to utilize the BioRC; BioRC facilitates integration and enhancement of access to information about biorepository specimens and resources; BioRC assists investigators in developing new projects that require the collection and processing of shareable samples not currently available, or helps investigators with existing projects who would like to migrate storage and management of their shareable banked specimens and data to the BioRC. BioRC institutes and follows best-practice standard procedures for collection, processing, and storage of samples to ensure high quality specimens and data for all CHOP investigators.
Proper citation: Children's Hospital of Philadelphia Research Institute CHOP Biorepository Resource Center Core Facility (RRID:SCR_023768) Copy
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