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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_E8FK
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: FGFR1 gene expression was genetically up-regulated. First transduced with a CRISPR-based Synergistic Activation Mediator (SAM) system composed of two lentiviral vectors dCAS-VP64_Blast (EF1a-dCas9-VP64-Bsd-WPE) and MS2-P65-HSF1-Hygro (EF1a-MS2(N55K)-SV40(NLS)-RELA-HSF1-hygR-WPRE) and then a PiggyBac transposon containing three unique SAM compatible gRNAs spanning the promoter region of FGFR1 (gFGFR1) and a puroR-IRES-AsRed-CMV construct (PubMed=30562682)., Population: Chinese; Han and Japanese.
Proper citation: RRID:CVCL_E8FK Copy
https://web.expasy.org/cellosaurus/CVCL_E3NZ
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: Fukushima Translational Research Project Patient-Derived Organoids (F-PDO) collection., Group: Cancer organoid.
Proper citation: RRID:CVCL_E3NZ Copy
https://web.expasy.org/cellosaurus/CVCL_E6J7
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: The ROS1 mutation introduced is most prevalent among patients presenting relapsed disease. Shows resistance to ceritinib, crizotinib, entrectinib and lorlatinib (DOI=10.63028/10067/2105480151162165141).
Proper citation: RRID:CVCL_E6J7 Copy
https://web.expasy.org/cellosaurus/CVCL_E6JC
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Does not show resistance to the five compounds tested (ceritinib, crizotinib, entrectinib, lorlatinib and repotrectinib) (DOI=10.63028/10067/2105480151162165141).
Proper citation: RRID:CVCL_E6JC Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0023
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed=29468137)., Characteristics: Expresses HPRT1 at the surface of the cell membrane (PubMed=28408844)., Population: Caucasian., Part of: NCI-7 clinical proteomics reference material cell line panel., Part of: NCI-60 cancer cell line panel., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: KuDOS 95 cell line panel., Part of: JFCR39 cancer cell line panel., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 2., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_0023 Copy
https://web.expasy.org/cellosaurus/CVCL_U094
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese and Lao.
Proper citation: RRID:CVCL_U094 Copy
https://web.expasy.org/cellosaurus/CVCL_U093
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RCB Cat# RCB2816, RRID:CVCL_U093 Copy
https://web.expasy.org/cellosaurus/CVCL_YD59
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_YD59 Copy
https://web.expasy.org/cellosaurus/CVCL_H268
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_H268 Copy
https://web.expasy.org/cellosaurus/CVCL_4V07
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_4V07 Copy
https://web.expasy.org/cellosaurus/CVCL_B0A6
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Has also reduced expression of IFITM1., Population: Caucasian.
Proper citation: RRID:CVCL_B0A6 Copy
https://web.expasy.org/cellosaurus/CVCL_A9ME
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: Caucasian.
Proper citation: RRID:CVCL_A9ME Copy
https://web.expasy.org/cellosaurus/CVCL_LI35
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9 a red fluorescent protein (RFP) tag was added to the C-terminal of the VIM gene. Allows to monitor the epithelial-to-mesenchymal transition (EMT) status of cells in vitro by monitoring RFP expression., Population: Caucasian.
Proper citation: RRID:CVCL_LI35 Copy
https://web.expasy.org/cellosaurus/CVCL_XB30
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_XB30 Copy
https://web.expasy.org/cellosaurus/CVCL_A0VZ
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a CBG-T2A-GFP construct., Population: Caucasian.
Proper citation: RRID:CVCL_A0VZ Copy
https://web.expasy.org/cellosaurus/CVCL_RQ89
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Using ZFN a TagGFP2 construct was integrated at the C-terminus of the STAT1 gene (Sigma-Aldrich=CLL1158)., Population: Caucasian.
Proper citation: RRID:CVCL_RQ89 Copy
https://web.expasy.org/cellosaurus/CVCL_DF40
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Discontinued: Sartorius/Essen Biosciences; Catalog number 4491., Characteristics: Stably expresses a non-perturbing nuclear restricted red fluorescent label., Population: Caucasian.
Proper citation: RRID:CVCL_DF40 Copy
https://web.expasy.org/cellosaurus/CVCL_QZ78
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with both the LV-Fluc-P2A-Neo and LV-iRFP-P2A-Puro vectors. LV-Fluc-P2A-Neo encodes for luciferase linked via a P2A cleavage peptide to the neo gene and under control of the spleen focus-forming virus (SFFV) promoter. LV-iRFP-P2A-Puro encodes for iRFP linked via a P2A cleavage peptide to the PuroR gene and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL098)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ78 Copy
https://web.expasy.org/cellosaurus/CVCL_5I86
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_5I86 Copy
https://web.expasy.org/cellosaurus/CVCL_A9MD
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: Caucasian.
Proper citation: RRID:CVCL_A9MD Copy
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