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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_JK07
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: More sensitive to the ALK inhibitor crizotinib when compared to the parental cell line. Can be a useful model to study tyrosine kinase signaling pathway and to screen ALK inhibitors., Characteristics: An EML4-ALK4 fusion was generated by CRISPR/Cas9., Population: Caucasian.
Proper citation: RRID:CVCL_JK07 Copy
https://web.expasy.org/cellosaurus/CVCL_XE68
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: Caucasian.
Proper citation: RRID:CVCL_XE68 Copy
https://web.expasy.org/cellosaurus/CVCL_XI06
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Group: Patented cell line.
Proper citation: RRID:CVCL_XI06 Copy
https://web.expasy.org/cellosaurus/CVCL_A7UW
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Expresses ACE2 with C-terminal HA and FLAG tags under the control the CMV promoter (BEI_Resources=NR-53522)., Population: Caucasian., From: Garcia-Sastre, Adolfo; Icahn School of Medicine at Mount Sinai Medical School; New York; USA., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A7UW Copy
https://web.expasy.org/cellosaurus/CVCL_YZ46
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_YZ46 Copy
https://web.expasy.org/cellosaurus/CVCL_5I73
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB binding sites. The Lucia luciferase reporter gene is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=a549d-nfis)., Population: Caucasian.
Proper citation: RRID:CVCL_5I73 Copy
https://web.expasy.org/cellosaurus/CVCL_RX08
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter., Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency., Population: Caucasian.
Proper citation: RRID:CVCL_RX08 Copy
https://web.expasy.org/cellosaurus/CVCL_UR31
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CCL-185-LUC2)., Population: Caucasian.
Proper citation: RRID:CVCL_UR31 Copy
https://web.expasy.org/cellosaurus/CVCL_A1ZW
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Selected to grow at low density., Population: Caucasian.
Proper citation: RRID:CVCL_A1ZW Copy
https://web.expasy.org/cellosaurus/CVCL_A9MB
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Transduced with a Cas9-FLAG-Neo construct., Population: Caucasian.
Proper citation: RRID:CVCL_A9MB Copy
https://web.expasy.org/cellosaurus/CVCL_QZ84
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with the LV-iRFP-P2A-Neo which encodes for iRFP linked via a P2A cleavage peptide to the PuroR gene and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL081)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ84 Copy
https://web.expasy.org/cellosaurus/CVCL_XB31
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_XB31 Copy
https://web.expasy.org/cellosaurus/CVCL_QZ80
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Reporter cell line, transduced with the LV-hNIS-IRES-Neo vector encoding for human SLC5A5 linked via an internal ribosomal entry site (IRES) to the Neo gene and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL004)., Population: Caucasian.
Proper citation: RRID:CVCL_QZ80 Copy
https://web.expasy.org/cellosaurus/CVCL_A7UV
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Expresses ACE2 under the control of the EF1a promoter (BEI_Resources=NR-53821)., Population: Caucasian., From: Baric, Ralph Steven; Department of Epidemiology, University of North Carolina at Chapel Hill; Chapel Hill; USA., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A7UV Copy
https://web.expasy.org/cellosaurus/CVCL_IP03
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_IP03 Copy
https://web.expasy.org/cellosaurus/CVCL_YA87
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Established following in vivo propagation of parent cell line as an ascites tumor (PubMed=3129183)., Population: Caucasian.
Proper citation: RRID:CVCL_YA87 Copy
https://web.expasy.org/cellosaurus/CVCL_W192
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_W192 Copy
https://web.expasy.org/cellosaurus/CVCL_UJ32
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_UJ32 Copy
https://web.expasy.org/cellosaurus/CVCL_A5KB
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Virology: Highly susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) and/or spike-pseudotyped lentiviral particles (InvivoGen=a549-hace2tpsa)., Population: Caucasian., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A5KB Copy
https://web.expasy.org/cellosaurus/CVCL_A7ZQ
Organism: Homo sapiens (Human)
Disease: Lung adenocarcinoma
Category: Cancer cell line
Comments: Characteristics: Stably expresses two reporter genes: SEAP (secreted ALPP) and the Lucia luciferase. In this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB binding sites. The Lucia luciferase reporter gene is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=a549d-cov2r)., Characteristics: Ideal for studying SARS-CoV-2 viral entry into host cells, the viral RNA sensing pathway, as well as screening small molecule inhibitors and neutralizing antibodies. These cells are permissive to infection by SARS-CoV-2 Spike-pseudotyped viral particles (InvivoGen=a549d-cov2r)., Population: Caucasian., Group: SARS-CoV-2 research cell line.
Proper citation: RRID:CVCL_A7ZQ Copy
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