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URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245494
Proper Citation: RRID:RRRC_00633
Description: Rattus norvegicus with name SD-Tg(TRE-TARDBP-M337V) from RGD.
Species: Rattus norvegicus
Notes: Strain carries a transgene expressing human TDP43 with the M337V mutation under control of a tTA-dependent promoter (TRE). When mated to a second transgenic strain (RRRC:632) that carries a tetracycline-controlled transactivator driven by the mouse choline acetyltransferase (Chat) promoter, the expression of mutant TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center
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Source: Integrated Animals
Source Database: Rat Resource and Research Center (RRRC)
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