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Proper Citation: RRID:MGI:3697081
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal cochlear endolymph ionic homeostasis, thin spiral ligament, endocrine/exocrine gland phenotype, abnormal strial basal cell morphology, small scala tympani, thin stria vascularis, stria vascularis degeneration, organ of Corti degeneration, absent endocochlear potential, abnormal strial marginal cell morphology, abnormal strial intermediate cell morphology, sensorineural hearing loss, dilated endolymphatic duct, dilated cochlea, decreased endocochlear potential, deafness, abnormal calcium ion homeostasis, increased or absent threshold for auditory brainstem response, head tilt, enlarged otoliths, abnormal vestibular endolymph, abnormal calcium ion homeostasis, circling, abnormal vestibular endolymph ionic homeostasis, abnormal spiral limbus morphology, dilated scala media, type II spiral ligament fibrocyte degeneration, type I spiral ligament fibrocyte degeneration, distended Reissner membrane, absent endocochlear potential, abnormal strial intermediate cell morphology, thin spiral ligament, organ of Corti degeneration, abnormal strial basal cell morphology, cochlear hair cell degeneration, enlarged otoliths, abnormal strial marginal cell morphology, stria vascularis degeneration, endocrine/exocrine gland phenotype, nonsyndromic hearing loss
Affected Gene: Slc26a4
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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