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URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: hemoglobin beta chain complex|nicotinamide nucleotide transhydrogenase|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|glucose homeostasis QTL 2|purinergic receptor P2X; ligand-gated ion channel; 7|microwave induced increase in complement receptor B cells|nuclear encoded tRNA arginine 5 (anticodon TCT)|annexin A6|forebrain weight 2|arylalkylamine N-acetyltransferase|gamma-aminobutyric acid type A receptor subunit alpha 2|MX dynamin-like GTPase 1|CD5 antigen|forebrain weight 1|beta-2 microglobulin|glucose homeostasis QTL 3|glucose homeostasis QTL 1|latent transforming growth factor beta binding protein 4|aryl-hydrocarbon receptor|cytochrome c oxidase subunit 7A2 like|NLR family; pyrin domain containing 12|cadherin related 23 (otocadherin); inbred strain: Hbb|Nnt|Apobec3|Gluchos2|P2rx7|Micrl|n-TRtct5|Anxa6|Fbrwt2|Aanat|Gabra2|Mx1|Cd5|Fbrwt1|B2m|Gluchos3|Gluchos1|Ltbp4|Ahr|Cox7a2l|Nlrp12|Cdh23
Affected Gene: hemoglobin beta chain complex|nicotinamide nucleotide transhydrogenase|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|glucose homeostasis QTL 2|purinergic receptor P2X; ligand-gated ion channel; 7|microwave induced increase in complement receptor B cells|nuclear encoded tRNA arginine 5 (anticodon TCT)|annexin A6|forebrain weight 2|arylalkylamine N-acetyltransferase|gamma-aminobutyric acid type A receptor subunit alpha 2|MX dynamin-like GTPase 1|CD5 antigen|forebrain weight 1|beta-2 microglobulin|glucose homeostasis QTL 3|glucose homeostasis QTL 1|latent transforming growth factor beta binding protein 4|aryl-hydrocarbon receptor|cytochrome c oxidase subunit 7A2 like|NLR family; pyrin domain containing 12|cadherin related 23 (otocadherin)
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: JAX Mice and Services
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