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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154598
Proper Citation: RRID:RGD_598154598
Description: Rattus norvegicus with name F344.W-np/Shi from RGD.
Species: Rattus norvegicus
Notes: In 1983, Wistar rats with pleural and ascites effusions and severe skin oedema were found at the Shionogi Pharmaceutical Co. The rats were named Nephrose Shionogi (NPS) because they showed nephrosis (F12). Breeding revealed that this phenotype was dominated by a autosomal recessive gene, np. NPS rats develop nephrosis at 4 weeks of age and die within 2 weeks. To prolong survival, NPS rats (np/+) were backcrossed with F344/Shi rats to generate the congenic strain (N12-13). National BioResource Project for the Rat in Japan
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Source: Rat Genome Database (RGD) (RRID:SCR_006444)
Description: Database for genetic, genomic, phenotype, and disease data generated from rat research. Centralized database that collects, manages, and distributes data generated from rat genetic and genomic research and makes these data available to scientific community. Curation of mapped positions for quantitative trait loci, known mutations and other phenotypic data is provided. Facilitates investigators research efforts by providing tools to search, mine, and analyze this data. Strain reports include description of strain origin, disease, phenotype, genetics, immunology, behavior with links to related genes, QTLs, sub-strains, and strain sources.
URL: http://rgd.mcw.edu
Source Database: Rat Genome Database (RGD)