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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=69558
Proper Citation: RRID:MMRRC_069558-UCD
Description: Mus musculus with name B6.Cg-Rapgef3tm1.1Chen/ChengMmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Dermatology, Diabetes, Endocrine Deficiency, Immunology and Inflammation, Internal/Organ, Metabolism, Models for Human Disease, Neurobiology, Obesity, Research Tools, Virology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased body weight [MP:0001262]| abnormal glucose homeostasis [MP:0002078]| decreased circulating insulin level [MP:0002727]| increased insulin sensitivity [MP:0002891]| improved glucose tolerance [MP:0005292]| decreased circulating glucose level [MP:0005560]| decreased circulating leptin level [MP:0005668]| slow postnatal weight gain [MP:0008489]| decreased white fat cell size [MP:0009133]| decreased epididymal fat pad weight [MP:0009289]| decreased total body fat amount [MP:0010025]| abnormal adipose tissue development [MP:0011167]| decreased food intake [MP:0011940]
Affected Gene: Rapgef3
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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