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URL: https://www.mmrrc.org/catalog/cellLineSDS.php?mmrrc_id=60318
Proper Citation: RRID:MMRRC_060318-UCD
Description: Mus musculus with name KOMP ES cell line Pkn2tm1a(KOMP)Wtsi from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP
Phenotype: abnormal vascular development [MP:0000259]| open neural tube [MP:0000929]| abnormal somite development [MP:0001688]| abnormal embryo turning [MP:0001700]| absent vitelline blood vessels [MP:0001719]| disorganized yolk sac vascular plexus [MP:0001723]| pericardial edema [MP:0001787]| abnormal developmental patterning [MP:0002084]| abnormal neural tube morphology [MP:0002151]| no abnormal phenotype detected [MP:0002169]| abnormal neural crest cell migration [MP:0002950]| abnormal vitelline vasculature morphology [MP:0003229]| absent pharyngeal arches [MP:0003874]| abnormal rostral-caudal body axis extension [MP:0003885]| abnormal neural fold formation [MP:0004837]| abnormal mesenchyme morphology [MP:0006301]| craniorachischisis [MP:0008784]| delayed heart looping [MP:0009328]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0011702]| abnormal fibroblast proliferation [MP:0012176]| abnormal head development [MP:0013925]| abnormal vascular plexus formation [MP:0014138]
Affected Gene: |Pkn2|
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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