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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=42059
Proper Citation: RRID:MMRRC_042059-JAX
Description: Mus musculus with name B6;129P2-Ptentm1Mak/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Developmental Biology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal brain development [MP:0000913]| open neural tube [MP:0000929]| abnormal somite development [MP:0001688]| decreased embryo size [MP:0001698]| abnormal placenta morphology [MP:0001711]| abnormal allantois morphology [MP:0001726]| increased mammary adenocarcinoma incidence [MP:0001883]| increased tumor incidence [MP:0002020]| increased T cell derived lymphoma incidence [MP:0002024]| increased leukemia incidence [MP:0002026]| increased adrenal gland tumor incidence [MP:0002031]| increased carcinoma incidence [MP:0002038]| increased skin papilloma incidence [MP:0002051]| abnormal developmental patterning [MP:0002084]| abnormal embryonic tissue morphology [MP:0002085]| abnormal seminiferous tubule morphology [MP:0002216]| colon polyps [MP:0003269]| kinked neural tube [MP:0003400]| embryonic growth retardation [MP:0003984]| disorganized embryonic tissue [MP:0003988]| failure of initiation of embryo turning [MP:0004180]| increased incidence of tumors by ionizing radiation induction [MP:0004500]| enlarged allantois [MP:0004556]| increased endometrial carcinoma incidence [MP:0004868]| enlarged Peyer's patches [MP:0008136]| endometrium hyperplasia [MP:0009092]| failure of chorioallantoic fusion [MP:0009657]| increased skin squamous cell carcinoma incidence [MP:0009704]| increased mammary gland tumor incidence [MP:0010299]| increased hamartoma incidence [MP:0010306]| increased prostate gland tumor incidence [MP:0010357]| increased fibroadenoma incidence [MP:0010364]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0011108]| embryonic lethality during organogenesis [MP:0012431]
Affected Gene: Pten
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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