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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=33003
Proper Citation: RRID:MMRRC_033003-MU
Description: Mus musculus with name 129S1.129(Cg)-Nr0b1tm1.1Lja/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Developmental Biology, Endocrine Deficiency, Models for Human Disease, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal testis morphology [MP:0001146]| small testis [MP:0001147]| Leydig cell hyperplasia [MP:0001152]| seminiferous tubule degeneration [MP:0001154]| abnormal spermatogenesis [MP:0001156]| male infertility [MP:0001925]| abnormal lipid homeostasis [MP:0002118]| Sertoli cell hyperplasia [MP:0002776]| abnormal Leydig cell morphology [MP:0002786]| abnormal Sertoli cell development [MP:0004109]| abnormal efferent ductules of testis morphology [MP:0004728]| absent germ cells [MP:0004806]| decreased testis weight [MP:0004852]| decreased male germ cell number [MP:0004901]| increased testis tumor incidence [MP:0006262]| rete testis obstruction [MP:0006417]| abnormal testis cord formation [MP:0006418]| disorganized testis cords [MP:0006419]| abnormal peritubular myoid cell morphology [MP:0006420]| decreased number of peritubular myoid cells [MP:0006421]| ectopic Leydig cells [MP:0006427]| ectopic Sertoli cells [MP:0006428]| retention of the adrenal gland x-zone [MP:0008297]| dilated seminiferous tubules [MP:0009257]| polyovular ovarian follicle [MP:0009433]| abnormal seminiferous tubule epithelium morphology [MP:0011750]| abnormal fetal Leydig cell differentiation [MP:0013603]
Affected Gene: Nr0b1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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