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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=29875
Proper Citation: RRID:MMRRC_029875-MU
Description: Mus musculus with name B6.129S6-Ptprjtm1Taka/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Hematology, Immunology and Inflammation, Internal/Organ, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal vascular development [MP:0000259]| failure of vascular branching [MP:0000264]| abnormal heart development [MP:0000267]| distended pericardium [MP:0000292]| absent atrioventricular cushions [MP:0000298]| microcephaly [MP:0000433]| decreased embryo size [MP:0001698]| abnormal myocardial trabeculae morphology [MP:0002189]| thin myocardium [MP:0002652]| abnormal vascular branching morphogenesis [MP:0003227]| abnormal vitelline vasculature morphology [MP:0003229]| abnormal pericyte morphology [MP:0003719]| vascular smooth muscle hypoplasia [MP:0003814]| abnormal endocardium morphology [MP:0003974]| embryonic growth retardation [MP:0003984]| abnormal vitelline vascular remodeling [MP:0004076]| abnormal dorsal aorta morphology [MP:0004787]| abnormal vascular smooth muscle morphology [MP:0005592]| abnormal vascular endothelial cell morphology [MP:0006055]| increased vascular endothelial cell number [MP:0006056]| delayed heart looping [MP:0009328]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0011108]| embryonic lethality during organogenesis [MP:0012253]| incomplete penetrance [MP:0012501]
Affected Gene: Ptprj
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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